Clinical trials: Dietary Modification
Metabolic Syndrome X, Weight Loss
Effect of Two Diets With Different Content of Protein on Weight Loss in Adults With Metabolic Syndrome
Randomised clinical trial with a 6-month follow-up in Mexican adult men and women (20-65 years) with Metabolic Syndrome (MS). The sample size was calculated using a formula that compares two means, an alpha of 0.05 and a power of…
- Trial name
- DPMS (NCT02278757)
- Testing
- High protein diet, Low protein diet
- Where
- Mexico
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Mexican National Institute of Public Health
Diabete Type 2, Diabetes
The Healthy Eating and Active Living to Reverse Diabetes Pilot Study
The HEAL Diabetes Program is a multicomponent intensive plant-forward healthy eating program designed to reverse diabetes. Several recent studies, most notably the Diabetes UK-funded Diabetes Remission Clinical Trial (DiRECT) in…
- Conditions
- Diabete Type 2, Diabetes, Overweight , Obesity
- Trial name
- HEAL Diabetes (NCT07316569)
- Testing
- Intensive Multicomponent Healthy Eating and Weight Loss Intervention, Enhanced Usual Diabetes Care
- Where
- 2 sites in United States
- Volunteers
- 35 people
- Sponsor
- University of Tennessee
Diabetes, Diabetes Mellitus, Type 2
INITIATE Plus (INITiation of Insulin to Reach A1c TargEt) Study
This trial is conducted in the United States of America (USA). The purpose of this study is to compare the effectiveness and safety of a biphasic insulin aspart standard titration regimen when coupled with dietary intervention to…
- Trial name
- INITIATE plus (NCT00101751)
- Testing
- biphasic insulin aspart, dietary regimen
- Where
- United States
- Volunteers
- 4,877 people
- Sponsor
- Novo Nordisk A/S
Cystic Fibrosis, Cystic Fibrosis-related Diabetes
A Pilot Study of a Low Glycemic Load Diet in Adults With Cystic Fibrosis
This pilot study will evaluate the safety and tolerability of a low glycemic load dietary intervention in adult patients with cystic fibrosis (CF) in a rigorous feeding study.
- Conditions
- Cystic Fibrosis, Cystic Fibrosis-related Diabetes, Cystic Fibrosis With Intestinal Manifestations
- Trial name
- NCT04519853
- Testing
- Low Glycemic Load Diet
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Boston Children's Hospital
Alzheimer Disease
Nutrition Interventions for Cognitive Enhancement
By doing this study, researchers hope to learn how the Mediterranean and low-fat eating patterns affect memory, brain volume, brain antioxidant status and cardio-metabolic biomarkers, such as blood pressure and blood glucose, in…
- Trial name
- NICE (NCT03841539)
- Testing
- Mediterranean Diet, Study Supplement, Low-fat Diet
- Where
- United States
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Type 2 Diabetes
The DR-EAM Type 2 Diabetes Study
The goal of this 12-month interventional study is to analyse the clinical outcome benefits, scalability and cost-effectiveness of a digital Low-Calorie digital Type 2 diabetes mellitus (T2DM) remission program compared to usual…
- Trial name
- NCT05626842
- Testing
- Total Diet Replacement (800kcal/day)
- Where
- United Kingdom
- Volunteers
- 197 people
- Sponsor
- Oviva UK Ltd
Bipolar Disorder
Dietary Intervention for Bipolar Disorder
Bipolar disorder (BD) is a chronic, often disabling illness, and many individuals remain symptomatic despite pharmacotherapy. Significant mood variability often persists throughout the lifespan and predicts relapse, leading to…
- Trial name
- NCT02272010
- Testing
- Experimental Diet, Comparator Diet
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Milton S. Hershey Medical Center
Obesity, Metabolically Healthy Obesity
Exercise and Diet Responses in Adult Men With Obesity by MC4R Genotype and Metabolic Health
This study evaluated whether differences in the MC4R rs17782313 gene variant and metabolic health status were associated with different responses to a 12-week exercise and dietary intervention in adult men with obesity.
- Conditions
- Obesity, Metabolically Healthy Obesity, Metabolically Unhealthy Obesity
- Trial name
- NCT07750197
- Testing
- Supervised Aerobic and Resistance Exercise
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Harbin Sport University
Obesity
Health After Birth Intervention Trial
This trial is to assess the feasibility of a larger, definitive RCT and determine the clinical effectiveness of an NHS 1:1 programme versus a modified programme with a low carbohydrate dietary intervention (as per Feinman and…
- Trial name
- HABIT (NCT05137691)
- Testing
- Adapted NHS weight management 1:1 programme, NHS 1:1 weight management programme
- Where
- United Kingdom
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Queen Margaret University
Obesity, Pregnancy
CO-OP Trial: Community-based Outreach on Obesity in Pregnancy
Obesity is becoming more common and disproportionately affects the younger generation, the poor and certain ethnic groups. Nearly 50% of reproductive aged women are obese or overweight.
- Trial name
- CO-OP (NCT01841424)
- Testing
- Dietary counseling. Maintain a food diary.
- Where
- 2 sites in United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Missouri, Kansas City
Liver Transplantation, Metabolic Syndrome X
Mediterranean Diet and Protein-Sparing Modified Diet for Metabolic Syndrome in Liver Transplant Recipients
Many metabolic complications can develop after liver transplant including: diabetes, high blood pressure, obesity, heart attacks and stroke.
- Conditions
- Liver Transplantation, Metabolic Syndrome X, Obesity
- Trial name
- NCT02174783
- Testing
- Control group, Mediterranean diet, Protein-Sparing Modified Fast (PSMF)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- The Cleveland Clinic
Type 2 Diabetes
Application and Effectiveness Analysis of Internet-based Diabetes Prevention Program
This study was conducted to test the possibility of preventing or delaying the development of type 2 diabetes in individuals with impaired glucose tolerance and elevated fasting plasma glucose concentrations by internet-based…
- Trial name
- NCT01085682
- Testing
- Lifestyle counseling, Standard care
- Where
- South Korea
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea
Ketogenic Dieting, Weight Loss
Weight Loss for a Healthier You Programme
In view of the research gap in the safety of traditional ketogenic diet, there is a need for a healthy alternative to the ketogenic diet that reduces the individual's propensity to adverse diet choices.
- Conditions
- Ketogenic Dieting, Weight Loss, Obesity, Metabolic Syndrome
- Trial name
- NCT05049954
- Testing
- Calorie-Restricted Healthy Ketogenic Diet, Calorie-Restricted Low Fat Diet
- Where
- Singapore
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Hypertriglyceridemia, Diabetes Mellitus
Effect of Changing Diet on Fasting and Post Fat Load Lipoproteins
The study examines the effect of two diets on fasting and post fat load lipoproteins of subjects with type 2 diabetes with moderate hypertriglyceridemia.
- Trial name
- NCT00593424
- Testing
- Low Fat/High Carbohydrate, High Monounsaturated Fat/Low Carbohydrate
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Arkansas
Overweight and Obesity
Sulfur Amino Acids, Energy Metabolism and Obesity
The primary objective of the trial is to establish the effects of dietary sulfur amino acid (SAA) restriction on body weight, body composition and energy expenditure in humans.
- Trial name
- STAY (NCT04701346)
- Testing
- Low SAA diet, High SAA diet
- Where
- Norway
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Obesity
Effect of Speed of Weight Loss on Compensatory Mechanisms Activated During Weight Reduction
Obesity has become a global epidemic with huge public health implications. Although clinical significant weight loss (WL) can be achieved by a combination of diet and behavioral modification, strong metabolic adaptations, with…
- Trial name
- FVS (NCT01912742)
- Testing
- Very-low calorie diet (VLCD), Low calorie diet (LCD)
- Where
- Norway
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Iron Deficiency Anemia
Effect of Consuming Food Cooked in Iron Utensils on Iron Status in Children With Iron Deficiency Anemia (IDA)
Iron deficiency is a common problem in the world and more so in the developing countries with a prevalence of 64 % (using WHO cut-off values of Hb <11.0 g/dl) among children, 9-36 months of age.
- Trial name
- IDA (NCT01115023)
- Testing
- iron cooking pot
- Where
- India
- Volunteers
- 36 people
- Sponsor
- Dhande, Leena Ajay, M.D.
Nutritional Status, Omega 3 Fat Status
Association of Seafood Consumption and Nutritional Status Among Adolescent Girls
This study examines how seafood consumption, social changes, and climate change affect the nutrition and well-being of adolescent girls in south-western Bangladesh.
- Conditions
- Nutritional Status, Omega 3 Fat Status, Micronutrient Status, Fish Consumption
- Trial name
- AQUAFOOD (NCT07555197)
- Testing
- Assess natural behavior
- Where
- Bangladesh
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Pregnancy Related, Diet Modification
Effects of Diet on Pregnancy Outcome and Child Obesity
The purpose of the study is to compare 3 different diets in pregnancy, equal in calories, and fats, different in refined grains compared to whole grains as a source of carbohydrates, and in calories from carbohydrate, compared to…
- Conditions
- Pregnancy Related, Diet Modification, Obesity, Hypertension
- Trial name
- NCT03232762
- Testing
- Refined Grains, Whole Grains
- Where
- United States
- Volunteers
- 303 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Diabetes, Type 2, Obesity &Amp; Overweight
Calorie Restricted Dietary Intervention in Type 2 Diabetes Patients With Obesity for Remission
This study aims to induce remission of type 2 diabetes through dietary intervention for weight reduction.
- Trial name
- K-Direct2 (NCT07753447)
- Testing
- Contrave ER, Low-calorie meal box
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- Yeouido St. Mary's Hospital