Clinical trials: Diarrhoea;Acute
Diarrhea, Gastroenteritis
Rifaximin 200 mg Plus Oral Rehydration vs Oral Rehydration Alone in Children With Acute Diarrhea
The goal of this clinical trial is to learn how rifaximin 200 mg is processed in the body (pharmacokinetics) in children 6 to 11 years old with acute diarrhea that may be caused by bacteria.
- Conditions
- Diarrhea, Gastroenteritis, Bacterial Infection, Acute Diarrhea
- Trial name
- NCT07285785
- Testing
- Rifaximin 200 mg Tablet, Oral Rehydration Therapy (ORT)
- Where
- 10 sites in United States
- Volunteers
- 54 people
- Sponsor
- Bausch Health Americas, Inc.
Gastroenteritis Acute, Dehydration
Balanced Crystalloid vs Normal Saline in Pediatric Acute Gastroenteritis
Acute gastroenteritis (AGE) is among the most common reasons for paediatric emergency visits. Children with significant dehydration often require intravenous (IV) fluid therapy.
- Conditions
- Gastroenteritis Acute, Dehydration, Acidosis, Metabolic, Diarrhea
- Trial name
- NCT07610382
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Aydin Adnan Menderes University
Acute Watery Diarrhea
Comparison of WHO Treatment of Acute Watery Diarrhea With or Without Probiotic (Bacillus Clausii) in Children
This study aimed to compare WHO treatment of acute watery diarrhea with or without probiotic (bacillus clausii) in term of mean duration of diarrhea in children
- Trial name
- NCT06887374
- Testing
- Probiotic Bacillus Clausii
- Where
- Pakistan
- Volunteers
- 184 people
- Sponsor
- Muhammad Aamir Latif
Gastroenteritis
ENterogermina® (Bacillus Clausii) In the manaGeMent of diarrheA in Children
Primary: To demonstrate the efficacy of Enterogermina® in reducing the duration of acute diarrhea in children Secondary: To evaluate the safety of Enterogermina® in acute diarrhea in Indian children
- Trial name
- ENIGMA (NCT00457353)
- Testing
- Bacillus Clausii, Oral rehydration therapy
- Where
- India
- Volunteers
- 264 people
- Sponsor
- Sanofi
Diarrhoea;Acute
Effectiveness of Folic Acid Supplementation in Acute Watery Diarrhea Among Children Under 5 Years of Age
Folic acid is a palatable and easily available drug with no serious adverse effects. L-methylfolate is its biologically activated form and is preferred because of its direct availability for certain metabolic processes.
- Trial name
- NCT04782037
- Testing
- L-Methylfolate Calcium
- Where
- Pakistan
- Volunteers
- 324 people
- Sponsor
- King Edward Medical University
Diarrhea
Study to Evaluate Smecta® vs Placebo on the Time to Recovery Following an Acute Diarrhoea Episode in Adults
The purpose of this study is to evaluate whether Smecta® is more effective than placebo with respect to time to recovery following an acute diarrhoea episode.
- Trial name
- NCT00276328
- Testing
- Diosmectite (Smecta®)
- Where
- 31 sites in Morocco, Tunisia
- Volunteers
- 346 people
- Sponsor
- Ipsen
Diarrhea
Influence of Carob and Probiotics on Acute Diarrhea in Children
Comparison of Carob powder with probiotics vs oral hydration solution in diarrhea treatment in children.
- Trial name
- NCT01501305
- Testing
- Mineral solution, Carob powder with probiotics
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Hillel Yaffe Medical Center
Acute Diarrhea
Study With Medical Nutrition Product PTM202 in Pediatric Diarrhea
The purpose of this study is to determine whether a medical nutrition product, PTM202, along with standard of care, enhances recovery and reduces diarrhea morbidity in young children
- Trial name
- NCT01814202
- Testing
- PTM202
- Where
- Bangladesh
- Volunteers
- 68 people
- Sponsor
- PanTheryx, Inc.
Diarrhea
High Amylose Maize Starch for Treatment of Cholera
A randomized, double-blind trial in adult males with acute dehydrating diarrhea of cholera comparing the safety, tolerability and efficacy of HAMS HO-ORS, HAMS 2.5% Acetate HO-ORS, HAMS 6% Acetate HO-ORS and HO-ORS.
- Trial name
- RESTORS (NCT01823952)
- Where
- Bangladesh
- Volunteers
- 106 people
- Sponsor
- PATH
Acute Gastroenteritis
Efficacy of Gelatin Tannate in Treatment Acute Gastroenteritis in Children.
Gelatin tannate possesses astringent, antibacterial, and anti-inflammatory properties. It is increasingly being marketed as an antidiarrheal drug.
- Trial name
- NCT02280759
- Testing
- Gelatin Tannate
- Where
- Poland
- Volunteers
- 72 people
- Sponsor
- Medical University of Warsaw
Acute Gastroenteritis
Optimizing the Management of Acute Diarrhoeal Disease
Many children admitted to hospital in Botswana without bloody diarrhoea are presumed to have viral gastroenteritis and so not treated with antibiotics - but they may indeed have a treatable cause for their illness.
- Trial name
- NCT02803827
- Testing
- Rapid diagnostics, Probiotic
- Where
- 4 sites in Botswana
- Volunteers
- 276 people
- Sponsor
- Hamilton Health Sciences Corporation
Multiple Myeloma, Myelodysplastic Syndromes
A Study of Special Use Results Surveillance of Revlimid 5mg Capsules
To understand the safety and efficacy of Revlimid® 5 mg Capsules (hereinafter referred to as Revlimid) in all patients who are treated with it under the actual condition of use pursuant to the conditions of approval. 1.
- Trial name
- NCT02921802
- Where
- Japan
- Volunteers
- 4,626 people
- Sponsor
- Celgene
Acute Diarrhea, Acute Gastroenteritis
Efficacy of Racecadotril in Acute Watery Diarrhea in Children
The purpose of this study is to determine the effect of racecadotril in acute watery diarrhea in children. The investigators will evaluate the effect of product versus placebo.
- Trial name
- NCT01577043
- Testing
- Racecadotril
- Where
- Bolivia
- Volunteers
- 52 people
- Sponsor
- Centro Pediatrico Albina de Patino
Acute Infectious Diarrhoea in Children
Isoleucine Added ORS in Children With Diarrhoea
Efforts are continuing to improve the efficacy of oral rehydration solution in terms of reducing the severity (stool volume) and duration of diarrhoea (enhancement of recovery).
- Trial name
- NCT01034228
- Testing
- ORS + Isoleucine, ORS without Isoleucine
- Where
- Bangladesh
- Volunteers
- 50 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Chronic Pancreatitis, Inflammatory Bowel Diseases
Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study
This is a prospective, descriptive, observational research study designed to observe and document the clinical practice by domain experts, and how the knowledge of new findings that are published in the medical literature affect…
- Conditions
- Chronic Pancreatitis, Inflammatory Bowel Diseases, Hepatitis, NASH - Nonalcoholic Steatohepatitis
- Trial name
- GREAT1 (NCT04306939)
- Testing
- venipuncture, Questionnaires, Additional Sample Collections
- Where
- United States
- Volunteers
- 120,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Acute Diarrhea
Effects of Probiotics and/or Prebiotics on the Duration of Diarrhea and Hospitalization in Children
Acute diarrhea continues to be a major cause of childhood morbidity and mortality in developed and developing countries. Prevention and treatment of dehydration are the mainstays of therapy.
- Trial name
- PROBAGE (NCT01927094)
- Testing
- Probiotic, ORS
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 1,280 people
- Sponsor
- Eskisehir Osmangazi University
Diarrhoea
Immunological and Clinical Responses to Zinc in Children With Diarrhoea
Zinc deficiency has been found to be widespread among children in developing countries.Clinical and field studies have consistently observed an association between zinc deficiency and higher rates of infectious diseases…
- Trial name
- NCT00408356
- Testing
- Zinc
- Where
- Bangladesh
- Volunteers
- 338 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Acute Diarrhea, Acute Respiratory Infection
Improving Nighttime Access to Care and Treatment (Part 2)
Children in resource-limited settings who develop illness at night are often isolated from pre-emergency care, resulting in progression to an emergency because families are forced to wait until morning to seek care.
- Conditions
- Acute Diarrhea, Acute Respiratory Infection, Acute Febrile Illness
- Trial name
- INACT2 (NCT03943654)
- Testing
- MotoMeds Healthline- illness assessment and treatment recommendation for non-emergent cases by telephone
- Where
- Haiti
- Volunteers
- 391 people
- Sponsor
- University of Florida
Acute Respiratory Infection, Acute Bacterial Diarrhea
Clinical Decision Rules in the Emergency Department to Improve the Management of Acute Respiratory Infection and Acute Infectious Diarrhea
Acute respiratory infections (such as influenza-like illness and upper respiratory tract infection) and acute infectious diarrhea are, for the most part, conditions that do not require medical management or specific treatment.
- Trial name
- NCT05322694
- Where
- 3 sites in Canada
- Volunteers
- 1,474 people
- Sponsor
- Simon Berthelot
Diarrhoea;Acute, Diarrhea Travelers
Single Dose Antibiotic Treatment of Acute Watery Diarrhea, Rifaximin Versus Azithromycin, With Loperamide Adjunct
The purpose of this study is to compare a single dose of rifaximin with loperamide to the current standard approach of single dose azithromycin with loperamide for the treatment of acute watery traveler's diarrhea (TD).
- Trial name
- TrEAT_TD2 (NCT05677282)
- Testing
- Rifaximin 550 MG, Azithromycin 500 MG, Loperamide
- Where
- 4 sites in Djibouti, Honduras and 2 more
- Volunteers
- 150 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine