Clinical trials: Diaphragm
Diaphragm; Relaxation, Low Back Pain
Influence of Manual Relaxation of the Diaphragm on the Tension of the Posterior Superficial Fascia
The diaphragm performs many functions that are vital to the body as a whole. Some of them are not related only to ventilation. The diaphragm is part of the myofascial system in the human body.
- Trial name
- NCT05197907
- Testing
- Fascial release of diaphragm muscle., Classic massage of the abdomen.
- Where
- Poland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Amyotrophic Lateral Sclerosis (ALS)
Motor-Point Stimulation for Conditioning the Diaphragm of Patients With Amyotrophic Lateral Sclerosis (ALS)
The overall goal of this research is to delay the respiratory decline of patients with Amyotrophic Lateral Sclerosis (ALS) thereby increasing their lifespan by conditioning the diaphragm with laparoscopically placed electrodes.
- Trial name
- NCT00420719
- Testing
- Intramuscular diaphragm electrodes
- Where
- 8 sites in United States, France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Synapse Biomedical
Postoperative Pulmonary Complications, Cardiac Surgery
Diaphragmatic Inspiratory Amplitude as a Prognosticator for Postoperative Pulmonary Complications After Cardiac Surgery
Cardiac surgery is a critical intervention for a variety of cardiovascular conditions, yet it can frequently results in a spectrum of postoperative complications.
- Trial name
- NCT06396767
- Testing
- DIA measured via Ultrasonography
- Where
- Canada
- Volunteers
- 130 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Diaphragm Disease, Covid19
Effects of COVID-19 Infection and Critical Illness on Diaphragm Tissue Characteristics and Movement, Visualized With MRI
COVID-19-infection has a large impact on the respiratory system and possibly on the diaphragm, the main respiratory muscle. In ICU-patients, diaphragm weakness is associated with prolonged ICU-stay, difficult weaning and…
- Trial name
- NCT04735757
- Testing
- Contrast-enhanced MRI, Measurement of respiratory muscle force
- Where
- Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Acute Respiratory Failure, Mechanically Ventilated Patients
Concurrent Trigger Sensitivity Adjustment And Diaphragmatic Facilitation On Weaning From Mechanical Ventilation
As Acute respiratory failure (ARF) is a challenging serious condition especially when it necessitates intubation to deliver mechanical ventilation which is a fundamental strategy for supporting the respiratory function when the…
- Trial name
- NCT05387720
- Testing
- Manual diaphragmatic facilitation (PNF) technique, Trigger sensitivity adjustment on mechanical ventilation, concurrent trigger sensitivity adjustment and manual diaphragmatic facilitation (PNF) technique
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Cairo University
Obesity & Overweight, Childhood Obesity
Combined Inspiratory Muscle Training and Functional High-Intensity Interval Training in Boys With Obesity
Childhood obesity is associated with reduced cardiorespiratory fitness, impaired exercise tolerance, and altered respiratory mechanics.
- Trial name
- IMT and HIIT (NCT07810361)
- Testing
- Inspiratory Muscle Training, Functional High-Intensity Interval Training
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Gümüşhane Universıty
Mechanical Ventilation
DIAPHRAGM STRENGTH AND LUNG VOLUMES
Diaphragm dysfunction (loss of diaphragm strength) is common in the intensive care unit (ICU) patients using ventilators. The diaphragm is the main muscle of respiration and its dysfunction can prolong mechanical ventilation and…
- Trial name
- DIAVOLA (NCT07206459)
- Testing
- Healthy Patients, Critically Care Patients
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Pulmonary Fibrosis
Diaphragmatic Release vs Inspiratory Muscle Training in Pulmonary Fibrosis
This study evaluates the efficacy of adding manual Diaphragmatic Release Technique (DRT) versus Targeted Inspiratory Muscle Training (IMT) to standard medical therapy in patients with stable pulmonary fibrosis.
- Trial name
- DR-IMT-PF (NCT07810153)
- Testing
- Diaphragmatic Release Technique (DRT), Targeted Inspiratory Muscle Training (IMT)
- Volunteers
- 40 people
- Sponsor
- Pharos University in Alexandria
Muscle Weakness, Critical Illness
Electromagnetic Stimulation of the Phrenic Nerve in Critically Ill Mechanically Ventilated Patients (STIMIT-II)
Ventilator-induced diaphragmatic dysfunction is a common issue in critically ill patients. Muscle stimulation has shown to have beneficial effects in muscle groups on the extremities.
- Conditions
- Muscle Weakness, Critical Illness, Mechanical Ventilation Complication
- Trial name
- STIMIT-II (NCT05238753)
- Testing
- Non-invasive electromagnetic stimulation
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- Charite University, Berlin, Germany
Bariatric Surgery, Bariatric Surgery Candidate
Effect of Transcutaneous Electrical Nerve Stimulation on PODD in Bariatric Surgery Patients
Researchers aim to evaluate impact of transcutaneous electric nerve stimulator on the incidence of postoperative diaphragmatic dysfunction in patients living with obesity undergoing bariatric surgery
- Trial name
- NCT07569705
- Testing
- Transcutaneous nerve stimulator
- Where
- 2 sites in Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Hyperemesis Gravidarum
The Effect of Guided Imagery and Diaphragmatic Breathing Exercise in Pregnant Women With Hyperemesis Gravidarum
Objective: The aim of the researchers is to determine the effects of guided imagery and diaphragmatic breathing exercise application on nausea, vomiting severity, and anxiety level in pregnant with hyperemesis gravidarum.
- Trial name
- NCT05829473
- Testing
- Breathing Exercise Group, Guided Imagery Group
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Gaziantep Islam Science and Technology University
Chronic Neck Pain
Diaphragmatic Breathing and Electroacupuncture for Chronic Neck Pain
Chronic non specific neck pain is a prevalent musculoskeletal disorder with significant impact on pain, forward head posture, and neck disability.
- Trial name
- NCT07684092
- Testing
- physiotherapy care, diaphragmatic breathing, and electroacupuncture, physiotherapy care, simple focused breathing exercises, and electroacupuncture
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- University of Lahore
Respiratory System Abnormalities
Manual Diaphragm Release in Cleaning Laborer
This study intended to examine the effect of manual diaphragm release on pulmonary function, chest wall mobility, and functional ability in female occupational cleaners with respiratory hazards.
- Trial name
- NCT05802355
- Testing
- Manual Diaphragm Release, control group
- Where
- Saudi Arabia
- Volunteers
- 36 people
- Sponsor
- Maged Basha
Paraesophageal Hernia, Large Hiatal Hernia
Ovitex in Paraesophageal and Large Hiatal Hernia Repair
The purpose of the study is to evaluate the success of hiatal hernia repairs in patients with large (>5cm) or paraesophageal hernias when Ovitex LPR mesh used during the repair.
- Trial name
- OviPHeR (NCT06193551)
- Testing
- Ovitex LPR
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Foregut Research Foundation
Ovarian Cancer
Diaphragmatic Resection And Gynecological Ovarian Neoplasm
Prospective randomized phase IV study aimed to value the impact of diaphragmatic surgery and the useful of intra-operatory thoracic drain in advanced ovarian cancer.
- Trial name
- DRAGON (NCT03543462)
- Testing
- thoracic Drain Tube 24 Fr.
- Where
- Italy
- Volunteers
- 88 people
- Sponsor
- Catholic University of the Sacred Heart
COPD
Dose Response of Pursed Lip Breathing With Diaphragmatic Breathing On Pulmonary Functions in Patients With COPD
1. To determine the Effects of combined pursed lip breathing with diaphragmatic breathing on pulmonary functions in patient with COPD. 2.
- Trial name
- NCT04928729
- Testing
- Pursed Lip Breathing, Pursed Lip Breathing +DB, Conservative care
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Diaphragm
Defining the Normal Range for Maximal Sniff Diaphragm Thickening Fraction
This study is investigating the normal range of maximal diaphragm thickness during a sniff inspiratory manoeuvre using ultrasound in healthy subjects stratified by age and gender.
- Trial name
- SNIFF II (NCT03129386)
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Phrenic Nerve Palsy
Does Saline Injection Around Phrenic Nerve Reduce Incidence of Diaphragmatic Paresis Following Interscalene Block?
Hemi-diaphragmatic palsy is a common undesirable effect of interscalene block, with an incidence of up to 100%. Mechanism of palsy is thought to be related to spread of local anaesthetic anterior to the anterior scalene muscle.
- Trial name
- NCT02893228
- Testing
- Saline, Levobupivacaine
- Where
- Ireland
- Volunteers
- 36 people
- Sponsor
- The Adelaide and Meath Hospital, incorporating The National Children's Hospital
Premature Birth
Changes in Respiratory Effort in Preterm Infants
Continuous Positive Airway Pressure (CPAP) is used to treat preterm infants with an immature respiratory center and having respiratory distress. CPAP requires intensive care monitoring and special qualified staff.
- Trial name
- NCT02014493
- Testing
- High Flow Nasal Cannulae (HFNC), Continuous Positive Airway Pressure (CPAP)
- Where
- Norway
- Volunteers
- 21 people
- Sponsor
- St. Olavs Hospital
Postural Orthostatic Tachycardia Syndrome (POTS), Post-acute COVID-19 Syndromes
Effects of Auricular Vagus Nerve Stimulation Combined With Slow-paced Breathing on Individuals With Postural Orthostatic Tachycardia Syndrome.
This study investigates a non-pharmacological treatment approach for Postural Orthostatic Tachycardia Syndrome (POTS), a disorder of the autonomic nervous system characterized by an excessive increase in heart rate upon standing.
- Trial name
- NCT06996314
- Testing
- TVNS + Slow-Paced Breathing (TVNS+SDB), TVNS without Breathing Training (TVNS+NB)
- Volunteers
- 100 people
- Sponsor
- Ali Kapan