Clinical trials: Diabetes type2
Diabetes, Sleep Apnea
CPAP in Diabetes Type 2 Patients With Sleep Apnea
Aim: To assess if six months of treatment with CPAP associated with conventional drug therapy, contribute to improved glycemic control in patients with type 2 diabetes and sleep apnea-hypopnea syndrome SAHS)
- Trial name
- DM-SAHS (NCT01801150)
- Testing
- CPAP nasal treatment
- Where
- Spain
- Volunteers
- 61 people
- Sponsor
- Hospital Universitario La Paz
Diabetes Mellitus, Type 2
Impact of High Protein and Low Carbohydrate Smoothie Drinks in Type-2 Diabetes Mellitus
We compared between a regular high protein or a high protein and low carbohydrate smoothie drinks with conventional diabetic enteral drinks (Glucerna) on glucose homeostasis, insulin and lipid metabolism in type 2 diabetic and…
- Trial name
- NCT04577274
- Testing
- smoothie with regular formulas (SM), smoothie with low carbohydrate formulas (SMLS), conventional diabetic enteral drinks (Glucerna)
- Where
- Thailand
- Volunteers
- 43 people
- Sponsor
- Mahidol University
Diabetes Mellitus, Type II
Safety and Efficacy of Dutogliptin in Patients With Type 2 Diabetes Mellitus (T2DM) on Background Therapy With Pioglitazone
This study will evaluate the safety and efficacy of dutogliptin in patients with type 2 diabetes mellitus (T2DM) who are receiving background treatment with pioglitazone.
- Trial name
- NCT00970424
- Testing
- Dutogliptin
- Where
- 118 sites in United States, Belarus and 4 more
- Volunteers
- 252 people
- Sponsor
- Forest Laboratories
Type 2 Diabetes Mellitus
Efficacy and Safety of Dorner Tablets and Aspirin for Prevention of Arteriosclerosis Progress in Type 2 Diabetes Mellitus Patients
The objective was to evaluate the efficacy and safety of combination of beraprost and aspirin for prevention of arteriosclerosis progress in type 2 diabetes mellitus patients.
- Trial name
- NCT02786979
- Testing
- Beraprost, Aspirin
- Where
- 6 sites in China
- Volunteers
- 190 people
- Sponsor
- Astellas Pharma Inc
Diabetes Mellitus, Type 2
Effect of Probiotic Supplements on Metabolic Control of People With Type 2 Diabetes Mellitus in Greece
The goal of this interventional clinical study is to examine if there will be a change in metabolic indices (glycemic and lipid parameters) among persons with type 2 diabetes (T2D) who will receive a probiotic dietary supplement…
- Trial name
- NCT06032988
- Testing
- LactoLevure
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- Konstantinos Makrilakis, MD
Type 2 Diabetes Mellitus
Open Trial of Miglitol in Type 2 Diabetic Patients Treated With Biguanide
The purpose of this study is to evaluate the clinical efficacy and safety of Miglitol in patients with Type2 Diabetes Mellitus treated with Biguanide.
- Trial name
- NCT00334503
- Testing
- Miglitol
- Where
- 13 sites in Japan
- Sponsor
- Sanwa Kagaku Kenkyusho Co., Ltd.
Hypertension, Type 2 Diabetes Mellitus
Home Monitoring in the Management of Hypertension and Diabetes Mellitus
The home monitoring of automated measuring devices may improve the management of the chronic diseases, and may decrease the incidence of fatal disease.
- Trial name
- NCT00968786
- Testing
- Home monitoring
- Volunteers
- 100 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Kidney Transplant, Type 2 Diabetes
Sitagliptin Treatment in Patients With Type 2 DM After Kidney Transplant
This study is designed to look at the effect sitagliptin has on tacrolimus and sirolimus drug levels in kidney transplant patients. It is also designed to look at the side effects experienced in the transplant population.
- Trial name
- NCT00466518
- Testing
- Administration of sitagliptin
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Oklahoma
Type 2 Diabetes
Sitagliptin in the Elderly
Diabetes is common in the elderly; by the age of 70, approximately 25% of the population will have diabetes. Unfortunately, currently available medications are often not as effective or not well tolerated in older adults.
- Trial name
- NCT00451113
- Testing
- Sitagliptin 100 mg
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of British Columbia
Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1
Increasing DR Screening Through TOP: Supporting Implementation and Identifying Opportunities for Scale up in Ontario
It is recommended that people with diabetes have their eyes screened for retinopathy every 1-2 years. Retinopathy can lead to visual impairment and blindness, but early detection through regular retinal screening can help to…
- Trial name
- TOP (NCT03927859)
- Testing
- a mail letter, a phone call and a phone call plus mailed letter
- Where
- 2 sites in Canada
- Volunteers
- 420 people
- Sponsor
- Women's College Hospital
Diabetes Type 2
A Comparison Chocolate With and Without High Cocoa Solids in Patients With Type 2 Diabetes in a Randomised Clinical Trial
Type 2 diabetes is being acknowledged as a potential public health time bomb, whose incidence is predicted to double over the next 10 years in the UK, associated with the rise in obesity and increasing sedentary lifestyles.
- Trial name
- NCT01617603
- Testing
- Cocoa Polyphenols
- Where
- United Kingdom
- Volunteers
- 62 people
- Sponsor
- Société des Produits Nestlé (SPN)
Diabetes Mellitus, Type 2
Efficacy Assessment of Insulin Glargine Versus LiraglutidE After Oral Agents Failure
Primary objective: To demonstrate the superiority of insulin glargine over liraglutide in terms of percentage of patients reaching a Glycosylated Haemoglobin (HbA1c) < 7% at the end of the comparative period (24 weeks) in Type 2…
- Trial name
- EAGLE (NCT01117350)
- Testing
- Insulin glargine, Liraglutide, Metformin
- Where
- 136 sites in United States, Austria and 15 more
- Volunteers
- 978 people
- Sponsor
- Sanofi
Type 2 Diabetes Mellitus
Effect of Sitagliptin on Incretin Effect in Patients With Type 2 Diabetes Mellitus
The purpose of this study is to assess the effect of the DPP-4 inhibitor sitagliptin on the incretin effect in patients with type 2 diabetes mellitus.
- Trial name
- NCT00551590
- Testing
- Sitagliptin tablet, Saline infusion, Exendin(9-39) infusion
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Endothelial Dysfunction, Diabetes Mellitus
Endothelial Disfunction Treatment With Glimepiride/Metformin Combination (Glimetal) in Type 2 Diabetes Patients
The Purpose of this study was to evaluate the effect of the combination glimepiride/metformin over endothelial dysfunction (ED) in asymptomatic patients with type 2 diabetes mellitus (DM) using 13N-ammonia-positron emission…
- Trial name
- NCT01429818
- Testing
- Glimepiride/metformin, Metformin
- Where
- Mexico
- Volunteers
- 16 people
- Sponsor
- Laboratorios Silanes S.A. de C.V.
Heart Failure, Type 2 Diabetes Mellitus
Ketones, Muscle Metabolism, and SGLT2 Inhibitors - Protocol 1
To examine the effect of an increase in plasma beta-hydroxy-butyrate (B-OH-B) levels, spanning the physiologic and pharmacologic range (+0.5, +2.0, and +5.0 mmol/L), on: (i) parameters of left ventricular (LV) systolic and…
- Trial name
- Protocol1 (NCT03560323)
- Testing
- Beta-hydroxy-butyrate
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Diabetic Nephropathies
Doppler Ultrasound in Early Detection of Diabetic Nephropathy Type 2 Diabetes Mellitus.
Doppler sonography provides an easily applicable, non-invasive, and well-established method for investigating renal morphologic characteristics and measuring vascular resistance in the renal parenchyma.
- Trial name
- NCT03284996
- Testing
- Doppler ultrasonography
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Diabetes Mellitus, Type 2, Heat Exposure
Home-based Heat Therapy for Type 2 Diabetes
Insulin resistance and hyperglycemia predispose individuals with type 2 diabetes mellitus (T2DM) to endothelial dysfunction and a greater risk of cardiovascular diseases (CVD).
- Trial name
- NCT05269589
- Testing
- Thermoneutral water, Hot water
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- Montreal Heart Institute
Type 2 Diabetes, Multidisciplinary Communication
Visualisation of a Digital Care Pathway.
As part of the EFRO (Europees Fonds Regionale Ontwikkeling) 1302 project "Digital Care Support in Practice with Limburg as a Stepping Stone for Flanders", this study aims to evaluate the concept and added value of visualising a…
- Conditions
- Type 2 Diabetes, Multidisciplinary Communication, Empowerment, Patient Empowerment
- Trial name
- NCT05226182
- Testing
- visualisation of a digital care path
- Where
- Belgium
- Volunteers
- 45 people
- Sponsor
- Jessa Hospital
Type 2 Diabetes Mellitus
Safety And Tolerability Of Lixisenatide In Monotherapy In Patients With Type 2 Diabetes
Primary Objective: To assess the overall safety of lixisenatide once daily treatment in monotherapy over 24 and 52 weeks in patients with type 2 diabetes in Japan Secondary Objective: To assess the effects of lixisenatide once…
- Trial name
- NCT01960179
- Testing
- lixisenatide AVE0010
- Where
- 30 sites in Japan
- Volunteers
- 361 people
- Sponsor
- Sanofi
Type 2 Diabetes Mellitus
Targeting Inflammation Using Salsalate for Type 2 Diabetes-Stage II
Growing evidence over recent years supports a potential role for low grade chronic inflammation in the pathogenesis of insulin resistance and type 2 diabetes.
- Trial name
- TINSALT2D-II (NCT00799643)
- Testing
- Salsalate
- Where
- 21 sites in United States
- Volunteers
- 638 people
- Sponsor
- Joslin Diabetes Center