Clinical trials: Diabetes and Heart Failure
Heart Failure, Type 2 Diabetes
Transform: Teaching, Technology, and Teams
This initiative supports a quality improvement effort evaluating the use of strategies (including technology-based decision support, referral to a virtual GDMT team, and general educational tools/resources for clinicians and…
- Conditions
- Heart Failure, Type 2 Diabetes, Atrial Fibrillation
- Trial name
- T3 (NCT05572814)
- Testing
- Decision Support, Referral
- Where
- United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- American College of Cardiology
Asthma, Chronic Obstructive Pulmonary Disease (COPD)
Comparative Effectiveness of Telemedicine in Primary Care
Leveraging a natural experiment approach, the investigators will examine rapidly changing telemedicine and in-person models of care during and after the COVID-19 crisis to determine whether certain patients could safely choose to…
- Conditions
- Asthma, Chronic Obstructive Pulmonary Disease (COPD), Congestive Heart Failure, Diabetes
- Trial name
- NCT04684836
- Testing
- Exposure to telemedicine, after the onset of the pandemic
- Where
- 4 sites in United States
- Volunteers
- 33,100 people
- Sponsor
- Weill Medical College of Cornell University
Diabetes (DM), Hypertension
Multimodal Cardiovascular Magnetic Resonance Imaging for Cardiometabolic Pre-HF and HFpEF
This is an observational study aiming to characterize the pathophysiological features and clinical significance of cardiometabolic early-stage heart failure using advanced multimodal cardiovascular magnetic resonance (CMR)…
- Conditions
- Diabetes (DM), Hypertension, Heart Failure, Obesity & Overweight
- Trial name
- NCT07336316
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Diabetes Mellitus Type 2
A Comparative Study of Aleglitazar and Actos in Patients With Type 2 Diabetes Mellitus and New York Heart Association (NYHA) Class II Heart Failure.
This 2 arm study will compare the safety, tolerability and efficacy of aleglitazar and Actos in patients with type 2 diabetes and symptomatic NYHA class II heart failure.
- Trial name
- NCT00461058
- Testing
- Actos, aleglitazar
- Where
- 45 sites in United States, Israel and 4 more
- Volunteers
- 14 people
- Sponsor
- Hoffmann-La Roche
Heart Failure, Diabetes (DM)
The Force Frequency Relationship in Heart Failure and Diabetes Mellitus: a Metabolic Aetiology?
The present investigation is a non-randomised, observational study involving an unselected but highly phenotyped cohort of patients undergoing pacemaker or defibrillator implantation from whom a small sample of fat and muscle…
- Trial name
- NCT07309523
- Where
- United Kingdom
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Heart Failure Acute, Diabetes Type 2
SGLT-2 Inhibitor and High-Dose Furosemide Plus Small-Volume Hypertonic Saline Solution in Acute HF
The purpose of the current investigation is to demonstrate the efficacy of high-dose furosemide plus small-volume hypertonic saline solution and a Sodium-Glucose cotransporter-2 (SGLT-2) inhibitor among patients admitted for…
- Conditions
- Heart Failure Acute, Diabetes Type 2, Heart Failure With Reduced Ejection Fraction, Heart Failure With Preserved Ejection Fraction
- Trial name
- DAPA-TONIC (NCT06442280)
- Testing
- Dapagliflozin tablet, Hypertonic Saline Solution, 1 Ml, Furosemide Injection
- Volunteers
- 544 people
- Sponsor
- University of Palermo
Heart Failure, Coronary Artery Disease
PAtient Similarity for Decision-Making in Prevention of Cardiovascular Toxicity (PACT): A Feasibility Study
This is a single-center, double-arm, open-label, randomized feasibility study that will determine whether a novel clinical decision aid accessed via the electronic health record will be acceptable to both cancer survivors and…
- Conditions
- Heart Failure, Coronary Artery Disease, Peripheral Artery Disease, Ischemia
- Trial name
- NCT05377320
- Testing
- Clinical Decision Aid, Standard Care
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Medical College of Wisconsin