Clinical trials: Diabetes Mellitus Risk
Incidence and Types of Systemic Reactions Occurring After Spinal Steroid Injection in a Large Population
Incidence of Various Types of Systemic Reactions Related to Spinal Steroid Injection: A Prospective Study
Many systemic reactions occur commonly after spinal steroid injections, especially in patients, and may be associated with underlying disease, such as hypertension and diabetes mellitus, as well as steroid dose and repetition of…
- Trial name
- NCT01756196
- Testing
- Spinal Steroid Injection
- Where
- South Korea
- Volunteers
- 997 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Diabetes Mellitus, Type II
Empagliflozin Reduces Progression of Diabetic Retinopathy in Patients With High Risk of Diabetic Macular Edema
This is a prospective, randomized, active control, two-arm parallel, double-blind, monocenter phase IV clinical trial. The trial compares empagliflozin to glimepiride in patients with type 2 diabetes mellitus in addition to…
- Trial name
- NCT02985242
- Testing
- Empagliflozin, Glimepiride
- Where
- Germany
- Volunteers
- 6 people
- Sponsor
- Hannover Medical School
Gestational Diabetes
The Use of Early Pregnancy HbA1c in Predicting Excessive Fetal Growth in Women at Risk of Glucose Intolerance
The association of hyperglycaemia in pregnancy (gestational diabetes mellitus; GDM) with adverse maternal and fetal outcomes is clearly recognised.
- Trial name
- SHAPE (NCT04858386)
- Where
- United Kingdom
- Volunteers
- 1,314 people, healthy volunteers welcome
- Sponsor
- Belfast Health and Social Care Trust
RELATED REGISTRY SEARCH
HF Prevalence and Evolution of HF in DM II Patients at High Risk
This is an epidemiological, single-country, multicenter, 2-year prospective cohort study based on both primary and secondary data collection, which will include a representative sample of 300 eligible T2DM patients managed in…
- Trial name
- HF-LanDMark (NCT04482283)
- Where
- 10 sites in Greece
- Volunteers
- 245 people
- Sponsor
- AstraZeneca
Two-Dimensional Echocardiography
The Cardiopathic Features and Analysis of Risk Factors in the Elderly Diabetic
Objectives: To investigate the cardiac condition of the diabetic patients in our hospital in order to seek for the new diagnostic method of warning its cardiovascular complications in early times.
- Trial name
- NCT00940082
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Third Military Medical University
Diabetes Mellitus, Type 2, Cardiovascular Disease
High Potency Statins and the Risk of Diabetes
Statins are a class of cholesterol lowering medications that are prescribed for the prevention and treatment of cardiovascular disease.
- Trial name
- Statins-DM (NCT02518503)
- Testing
- Rosuvastatin (≥10 mg), Atorvastatin (≥20 mg), Simvastatin (≥40 mg)
- Volunteers
- 136,966 people
- Sponsor
- Canadian Network for Observational Drug Effect Studies, CNODES
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Managing Type 1 and High Risk Type 2 Diabetes in the Hospital Setting: Glucose as a Vital Sign
This program will provide patients with type 1 and high risk type 2 diabetes the safest hospitalization by using wireless continuous glucose monitoring devices (CGM) to track their glucose parameters in real-time similar to other…
- Trial name
- CGM (NCT03068273)
- Testing
- Real-time CGM data
- Where
- United States
- Volunteers
- 157 people
- Sponsor
- Scripps Whittier Diabetes Institute
Hyperglycemia, Diabetes Mellitus
Early Detection Initiative for Pancreatic Cancer
The Early Detection Initiative for Pancreatic Cancer is a multi-center prospective study to determine if algorithm-based screening in patients with glycemically defined new onset hyperglycemia and diabetes has the potential for…
- Conditions
- Hyperglycemia, Diabetes Mellitus, Pancreas Ductal Adenocarcinoma
- Trial name
- EDI (NCT04662879)
- Testing
- Enriching New-onset Diabetes for Pancreatic Cancer (ENDPAC) score, Abdominal imaging
- Where
- 2 sites in United States
- Volunteers
- 8,869 people
- Sponsor
- Pancreatic Cancer Action Network
Type 2 Diabetes Mellitus, Bone Fractures
Microarchitecture, Bone Strength and Fracture Risk in Type 2 Diabetes
This multicenter, prospective, observational cohort study will assess bone differences in women and men with type 2 diabetes mellitus (T2DM) with and without fragility fractures.
- Trial name
- DiabOS (NCT02551315)
- Where
- 5 sites in Switzerland
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Diabetic Foot, Amputation
Predictors of Foot Amputation in Diabetic Foot Ulcers
Diabetes affects 463 million population of the world. Diabetic foot is one of the complications of uncontrolled diabetes which can lead to amputation in 5- 24% of non-healing diabetic foot ulcers.
- Conditions
- Diabetic Foot, Amputation, Antibiotic Resistant Strain, Diabetic Foot Ulcer
- Trial name
- NCT05551988
- Testing
- Retrospective observational study of diabetic foot ulcer
- Where
- Pakistan
- Volunteers
- 110 people
- Sponsor
- Bolan Medical Complex Hospital Quetta Pakistan
Diabetes, Heart Disease
Worksite Lifestyle Program for Reducing Diabetes and Cardiovascular Risk in India
This study will test the implementation, effectiveness, cost-effectiveness, and acceptability of a worksite lifestyle improvement program that includes lifestyle education classes led by trained individuals from the worksite and…
- Conditions
- Diabetes, Heart Disease, Obesity
- Trial name
- NCT02813668
- Testing
- Lifestyle Intervention Training Program
- Where
- 2 sites in India
- Volunteers
- 2,108 people
- Sponsor
- Emory University
Atherosclerosis, Cardiovascular Diseases
Intensive Glycemic Control and Skeletal Health Study
The purpose of the ACCORD-BONE Study is to investigate the effects of intensive glycemic control for type 2 diabetes (in ACCORD participants) on factors related to bone health, including, fractures, falls, and bone mineral…
- Conditions
- Atherosclerosis, Cardiovascular Diseases, Hypercholesterolemia, Hypertension
- Trial name
- ACCORD-BONE (NCT00324350)
- Testing
- hypoglycemic agents, hydroxymethylglutaryl-CoA Reductase inhibitors, hypertensive agents
- Where
- 5 sites in United States, Canada
- Volunteers
- 7,287 people
- Sponsor
- University of California, San Francisco
Type 2 Diabetes, Dietary Intervention
Effects of Combining Cocoa and Soy in Type 2 Diabetes
Diabetes is an increasingly common condition affecting millions of people world wide. The cornerstone of treatment is lifestyle that includes looking at the way how people eat.
- Trial name
- NCT01754662
- Testing
- Soy protein, Isoflavones, Cocoa
- Where
- United Kingdom
- Volunteers
- 84 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Obesity
Comparison of Weight Loss Induced by Bariatric Surgery vs Conventional Treatment
Patients with overweight or obesity are in need to loose weight and represent a particularly challenging medical condition. Undoubtedly, any intervention achieving a negative energy balance over an extended time period will…
- Trial name
- NCT01572090
- Testing
- Lifestyle Changes, Adjustment of oral antidiabetics/insulin therapy, Laparoscopic sleeve gastrectomy
- Where
- Spain
- Volunteers
- 600 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Diabetes Mellitus, Insulin-Dependent
Analysis of Viral Infections' Exposition Preceding the Type 1 Diabetes (T1D) Diagnostic in Children of the Isis-Diab Cohort. Search for Explanations of of the Disease's Early Onset
The purpose of this study is to investigate viral factors determining the early onset of T1D. Thanks to the quantification of viral exposures of T1D patients before the disease onset with questionnaires and environmental…
- Trial name
- ISIS-VIRUS (NCT02425410)
- Testing
- Collect of data on viral environment of T1D patients, Collect of blood samples for DNA extraction and genetic characterization (GWAS)
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diabetes
Diabetes Outcomes and Unmet Resources
This study will refine and test the effectiveness of CareAvenue, an automated e-health tool that informs and activates patients with uncontrolled diabetes to take steps in accessing resources and engaging in self-care.
- Trial name
- NCT03950973
- Testing
- CareAvenue, Guest Assistance Program
- Where
- United States
- Volunteers
- 667 people
- Sponsor
- University of Michigan
Diabetes Mellitus, Hypertension
Impact of INsulin Sensitivity on Cardiovascular Risk Markers During 10-20 Years of FOllow up
The purpose of this study is to identify risk factors for insulin resistance and to investigate the influence of insulin sensitivity on development of cardiovascular risk markers like blood pressure, heart rate, body build…
- Conditions
- Diabetes Mellitus, Hypertension, Ischemic Heart Disease, Stroke
- Trial name
- INFO (NCT01412554)
- Where
- Norway
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Obesity, Type 2 Diabetes
Strength Training and Nutrition Development for African American Youth
The investigators are conducting an intervention study to examine the effects of a 16-week exercise and diet interventions on prevention of disease, specifically type 2 diabetes and heart disease, in African American youth.
- Conditions
- Obesity, Type 2 Diabetes, Cardiovascular Risk, Cancer
- Trial name
- STAND (NCT01441323)
- Testing
- Nutrition, Strength Training & Nutrition
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Diabetes Mellitus Type 2, Kidney Disease, Chronic
A Study of Alegitazar in Patients With Type 2 Diabetes And Chronic Kidney Disease (Alerenal Study)
This randomized, double-blind, placebo-controlled study will evaluate the potential of aleglitazar to reduce the risk of end stage renal disease and cardiovascular mortality in patients with type 2 diabetes mellitus and chronic…
- Trial name
- NCT01893242
- Testing
- Aleglitazar
- Sponsor
- Hoffmann-La Roche
Hypertension, Type 2 Diabetes
Lifestyle Intervention in Primary Health Care - the Björknäs Study
The purpose of this study is to determine whether a short group intervention programe aiming at lifestyle changes at a local health centre can improve risk factors for cardiovascular disease
- Conditions
- Hypertension, Type 2 Diabetes, Obesity, Dyslipidemia
- Trial name
- NCT00486941
- Testing
- Exercise and diet - based on DPS and DPP
- Where
- Sweden
- Volunteers
- 151 people
- Sponsor
- Umeå University
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