Clinical trials: Diabetes, open to volunteers
Type2 Diabetes, Coronary Heart Disease
Coronary Artery Calcium-guided Primary Prevention of Major Coronary Heart Disease in Asymptomatic Diabetes
To evaluate benefits of primary prevention of major coronary heart disease for asymptomatic coronary artery disease in type 2 diabetes mellitus based on the coronary artery calcium score Our proposal 1.
- Trial name
- NCT05267990
- Testing
- Multi-Detector Computed Tomography
- Where
- Taiwan
- Volunteers
- 2,000 people
- Sponsor
- JuFeng, Hsiao
Type 1 Diabetes
Clinical Characteristics of People With Long-term Type 1 Diabetes
Type 1 diabetes (T1D) is characterized by absolute insulin deficiency. Although the discovery and application of exogenous insulin has prolonged the lifespan of T1D patients, the chronic diabetic complications caused by long-term…
- Trial name
- NCT05359796
- Testing
- Chronic hyperglycemia, Residual islet function, Genetic variation
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Second Xiangya Hospital of Central South University
Autoimmune Diseases, Cardiovascular Disorders
Mesenchymal Stem Cells for the Treatment of Various Chronic and Acute Conditions
This multi-arm, multi-site study investigates the safety, tolerability, and efficacy of stem cell therapy for the treatment of various acute and chronic conditions.
- Conditions
- Autoimmune Diseases, Cardiovascular Disorders, Diabetes Complications, Integumentary Disease
- Trial name
- NCT04684602
- Testing
- PrimePro™/ PrimeMSK™
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Thomas Advanced Medical LLC
Diabete Type 2
Assessment of Personalized Follow-up in Prevention of Type 2 Diabetes
In France, the overall prevalence of diabetes was estimated at 5% of population in 2016, type 2 diabetes (T2DM) corresponding to 90% of cases.
- Trial name
- Proxipart (NCT05325710)
- Testing
- Study nurse intervention
- Where
- France
- Volunteers
- 230 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Sport Injury, Diabetes
A Complex Health Promotion Intervention in Parasport - The Safe & Healthy Parasport Project
The interest in Para sport is steadily increasing. A concern is, though, that elite Para athletes report a high incidence of injuries and illnesses.
- Conditions
- Sport Injury, Diabetes, Health Behavior, Illness Behavior
- Trial name
- NCT05317130
- Testing
- Athlete health monitoring
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Lund University
Non-Alcoholic Fatty Liver Disease, Non-alcoholic Fatty Liver
European Paediatric Non-Alcoholic Fatty Liver Disease Registry (EU-PNAFLD)
The EU-PNAFLD (The European Paediatric NALFD Registry) will be a network composed of European centres involved in the care of children with NAFLD, and will include Hepatologists, Endocrinologists, and Scientists, supported by…
- Conditions
- Non-Alcoholic Fatty Liver Disease, Non-alcoholic Fatty Liver, Non-alcoholic Steatohepatitis
- Trial name
- EU-PNAFLD (NCT04190849)
- Where
- 3 sites in Netherlands, United Kingdom
- Volunteers
- 2,000 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Type 1 Diabetes Mellitus, Autoimmune Diabetes
Effects Of Berberine Plus Inulin On Diabetes Care in Patients With LADA
The primary purpose of this study is to evaluate the effects of oral berberine (BBR) and inulin combined with insulin therapy on diabetes care in patients with LADA.
- Trial name
- NCT04698330
- Testing
- Berberine, Inulin
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Second Xiangya Hospital of Central South University
Gestational Diabetes, Insulin Resistance
Pregnancy Outcomes: Effects of Metformin Study (POEM Study)
One approach to prevent the rising burden of diabetes is to address the issue of gestational diabetes mellitus (GDM). GDM has a growing prevalence up to 5-10% (and even higher in specific subgroups), with a pregnant population…
- Trial name
- POEM (NCT02947503)
- Testing
- Metformin TEVA 850 mg
- Where
- 4 sites in Netherlands
- Volunteers
- 500 people
- Sponsor
- Bethesda Diabetes Research Center
Diabetes Mellitus, Type 2, Bariatric Surgery
Comparisons of Metabolic Effect of Sleeve Gastrectomy With Duodenojejunal Bypass and Sleeve Gastrectomy (MEDUSA): A Multicenter Randomized Controlled Trial
In this study, the effects of SG with DJB and SG alone for the treatment of type 2 diabetes mellitus (T2DM) will be compared in patients other than the two groups at both extremes who are expected to show excellent effects of…
- Conditions
- Diabetes Mellitus, Type 2, Bariatric Surgery, Surgical Procedures, Operative, Asians
- Trial name
- NCT05211375
- Testing
- Duodenojejunal bypass, Sleeve gastrectomy
- Where
- South Korea
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Diabetes Mellitus, Cardiovascular Diseases
The Risk Factors of Cardiovascular Disease in Elderly Diabetic Patients: A Prospective Cohort Study
In the previous cohort studies focused on diabetes in China, there were few studies on elderly patients with diabetes. The aim of this prospective cohort study was to investigate the prevalence, management and nutritional status…
- Conditions
- Diabetes Mellitus, Cardiovascular Diseases, Complication Diabetic
- Trial name
- NCT04544527
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Shanghai Zhongshan Hospital
Cardiac Arrest;In-hospital Cardiac Arrest; Methylprednisolone; Vasopressin; Adrenaline; Randomized Clinical Trial
VAsopressin and STeroids in Addition to Adrenaline in Cardiac Arrest - a Randomized Clinical Trial
This is an investigator initiated randomized, placebo controlled, double blind, superiority, multi-centre clinical trial. The estimated study project period runs over 3-4 years, including pilot phase.
- Trial name
- VAST-A (NCT05139849)
- Testing
- Vasopressin; Methylprednisolone; Hydrocortisone, Sodium chloride
- Where
- 2 sites in Sweden
- Volunteers
- 1,276 people
- Sponsor
- Tiohundra AB
Metabolic Syndrome
Cardiovascular Diseases and Diabetes Prevention Programme in Metabolic Syndrome (CDPP)
The metabolic syndrome population is at high-risk of cardiovascular diseases and diabetes. How to effectively control the risk factors of this population is the key to primary prevention of cardiovascular diseases and diabetes in…
- Trial name
- CDPP (NCT05105321)
- Testing
- Berberine, Healthy lifestyle intervention
- Where
- China
- Volunteers
- 5,200 people
- Sponsor
- Tang Yida
Diabete Type 2, Substance Abuse
Cost-effectiveness of the Care Pathways
In this study we research patient segmentation made by Suuntima-service and it´s impacts to Quality of care, Service use and Costs of care among Type 2 Diabetes patients and Substance Abuse patients.
- Trial name
- NCT04619836
- Where
- Finland
- Volunteers
- 2,500 people
- Sponsor
- Tampere University Hospital
Schizophrenia, Forensic Psychiatry
Dundrum Forensic Redevelopment Evaluation Study: D-FOREST Study.
The DUNDRUM Forensic Redevelopment Evaluation study (D-FOREST study) is a multi-site comprehensive evaluation of a complete National Forensic Mental Health Service.
- Conditions
- Schizophrenia, Forensic Psychiatry, Outcome Measure, Violence
- Trial name
- D-FOREST (NCT05074732)
- Where
- Ireland
- Volunteers
- 350 people
- Sponsor
- Health Service Executive, Ireland
Type 2 Diabetes, Vascular Calcification
Coronary Artery Calcification in Type 2 Diabetes Mellitus (USCAC Study)
Coronary artery calcification (CAC) is a common complication of type 2 diabetes mellitus(T2DM), which can significantly increase all-cause mortality and the incidence of serious cardiovascular events, and increase the burden of…
- Conditions
- Type 2 Diabetes, Vascular Calcification, Coronary Artery Calcification, Strains
- Trial name
- NCT04889053
- Where
- China
- Volunteers
- 1,400 people
- Sponsor
- University of South China
Gestational Diabetes, Type2 Diabetes
iGlucose® Remote Patient Monitoring Device as an Adjunct to Routine Glucose Meter Devices for Glycemic Management and Control in Gestational Diabetes
The purpose of this study is to investigate whether automation of glucose monitoring data to facilitate the total number of recommended and completed SMBG checks improve clinical outcomes for women living with gestational and…
- Conditions
- Gestational Diabetes, Type2 Diabetes, Pregnancy in Diabetic
- Trial name
- iGlucose (NCT04206748)
- Testing
- iGlucose Smart Meter System, Routine Care-RX meter
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Diabetes Complications, Cardiovascular Diseases
Diabetes Complications and the Risk of Cardiovascular and Cerebrovascular Diseases
This study is intended to include 3000 diabetic patients in our hospital to collect complete medical history data, comprehensively improve the screening of diabetic complications and cardiovascular and cerebrovascular risk…
- Conditions
- Diabetes Complications, Cardiovascular Diseases, Cerebrovascular Disease
- Trial name
- NCT04983277
- Testing
- no intervention
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Diabetes Mellitus, Biomarkers
Establishment and Clinical Validation of a New Technique for Early Diagnosis of Diabetic Nephropathy
Diabetic kidney disease(DKD) is a leading cause of chronic kidney disease and end-stage renal disease across the world. Early identification of DKD is vitally important for the effective prevention and control of it.
- Conditions
- Diabetes Mellitus, Biomarkers, Diabetic Kidney Disease, Early Diagnosis
- Trial name
- NCT04976426
- Volunteers
- 1,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Diabetes Mellitus, Type 2, Lifestyle Risk Reduction
Patient-Driven Lifestyle Modification Using FreeStyle Libre in Type 2 Diabetes Patients
We aim to provide medical nutritional therapy to patients with type 2 diabetes who are on oral hypoglycemic agents or on basal insulin only and monitor the glycemic response with flash glucose monitoring or self-monitoring of…
- Trial name
- PDF (NCT04932928)
- Testing
- FreeStyle Libre, Blood glucose meter
- Where
- South Korea
- Volunteers
- 126 people
- Sponsor
- Seoul National University Hospital
Diabetes Mellitus, Cardiovascular Diseases
Asian Diabetes Outcomes Prevention Trial
The aim of this study is to identify patients with DM at high risk of CVD using elevated N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels (>125pg/mL), and (2) intensify therapy using renin-angiotensin system (RAS)…
- Trial name
- ADOPT (NCT04286399)
- Testing
- Renin-angiotensin-aldosterone system inhibitors, Beta blocker, SGLT2 Inhibitor - Sodium Glucose Cotransporter Subtype 2 Inhibitor Product
- Where
- Singapore
- Volunteers
- 2,400 people
- Sponsor
- National Heart Centre Singapore