Clinical trials: Development
Autism Spectrum Disorder
Transcranial Magnetic Stimulation (rTMS) and Autism.
In this protocol we aim to use rTMS to better characterize STS role in normal and abnormal social cognition. With that purpose, we will measure the effect of inhibitory and excitatory rTMS on the fixation time on social scenes…
- Trial name
- TMSAUTISME (NCT01648868)
- Testing
- Transcranial Magnetic Stimulation (rTMS)
- Where
- France
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cockayne Syndrome
Metabolic Study of Cockayne Syndrome
Cockayne syndrome (CS) is related to defective DNA transcription and/or repair and belongs to the family of Nucleotide Excision Repair.
- Trial name
- METABO-CS (NCT03044210)
- Testing
- Metabolic evaluation
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Emergency Nursing Education, Cardiopulmonary Resuscitation Training
Development and Evaluation of an Emergency Nursing Care Training Program Focusing on CPR and Triage for the Lao People's Democratic Republic
In low- and middle-income countries, particularly the Lao People's Democratic Republic, limited infrastructure and constrained educational access create competency gaps and limited training opportunities for emergency nurses.
- Conditions
- Emergency Nursing Education, Cardiopulmonary Resuscitation Training, Triage Training
- Trial name
- NCT07871474
- Testing
- Emergency Nursing Training Program
- Where
- Laos
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Inje University
Inherited Metabolic Disorders
AI for Newborn Metabolic Screening
The goal of this clinical trial is to evaluate whether an artificial intelligence (AI)-based interpretation system can accurately diagnose inherited metabolic disorders in newborns undergoing routine screening.
- Trial name
- NCT07368504
- Testing
- Artificial intelligence-based interpretation system for newborn genetic metabolic disease screening
- Where
- China
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Molar Incisor Hypomineralization
HYPERSENSITIVITY IN MOLAR INCISOR HYPOMINERALISATION USING LOW LEVEL LASER IN CHILDREN
Molar Incisor Hypomineralisation (MIH) is a qualitative defect of enamel that shows asymmetrically involvement of one to four on first permanent molars (FPM) with or without incisor teeth involvement.
- Trial name
- NCT06154733
- Testing
- Photobiomodulation usinf low level laser therapy, Resin-based sealant, Glass ionomer sealant
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Executive Function
Fatty Acids and Executive Function Development in 7-12 Year Olds
Purpose: To examine the effect of the omega-6 to omega-3 fatty acid ratio on age-related changes in executive functions in children and older adults. Participants: Eighty-four typically-developing 7-to 12-year-old children.
- Trial name
- NCT02199808
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Obesity, Overweight
Use of a Mobile Application by Parents to Prevent Obesity in Their Children Apply for Your Health
Background. Lifestyles that promote a positive energy balance increase the prevalence of obesity. Due to the magnitude of this problem, community-level strategies are required on how to provide families with useful information to…
- Trial name
- NCT07376252
- Testing
- Applícate por tu salud
- Where
- Mexico
- Volunteers
- 743 people, healthy volunteers welcome
- Sponsor
- Hospital Infantil de Mexico Federico Gomez
Traumatic Dental Injury, Autism Spectrum Disorder
Occurrence of Traumatic Dental Injury in a Group of Egyptian Autistic Children Compared to Normal Children: (A Cohort Study)
The aim of the study is to assess the occurrence of traumatic dental Injury in a group of Egyptian Autistic Children compared to normal children. Population: Egyptian children Exposure: Autistic children.
- Conditions
- Traumatic Dental Injury, Autism Spectrum Disorder, Dental Trauma
- Trial name
- NCT04235543
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Cairo University
Autism Spectrum Disorder
Development and Validation of a System for the Anticipation of Challenging Behaviors
Most people with autism spectrum disorder (ASD) present at least one form of challenging behavior (CB). Self-injurious, aggressive, and disruptive CBs linked with social interaction, community-based service exclusion, and a life…
- Trial name
- NCT05340608
- Testing
- Smart, non-invasive shirt - Physiological parameters, Smart, non-invasive shirt - Relation with challenging behaviors, Smart, non-invasive shirt - Proof of Concept
- Where
- Israel
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Ariel University
Healthy Volunteers
Imaging Techniques in CT: Technical Development
Background: Computed tomography (CT) scanning is a procedure that helps doctors with diagnoses. It uses X-ray radiation to produce an image in three dimensions.
- Trial name
- NCT02242448
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
T1DM, Brain Development
Brain Health and Development With T1DM
Type 1 diabetes mellitus (T1DM) is typically diagnosed in childhood and over time can lead to complications affecting the retina, heart, kidneys, peripheral nerves, and more recently appreciated, the brain.
- Trial name
- NewT (NCT03335878)
- Where
- United States
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Polycystic Ovarian Syndrome
In-Vitro Maturation of Oocytes From Polycystic Ovarian Patients Undergoing IVF
Retrieval of immature oocytes from women with polycystic ovaries, their in-vitro maturation, fertilization and embryo transfer can prevent hormonal treatment that can lead to ovarian hyperstimulation.
- Trial name
- IVM (NCT00561808)
- Testing
- In-vitro maturation oocytes
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Stress
The Effects of a Relaxation Intervention on College Students' Social-emotional Competence
Objective: To examine the impact of a psychomotor relaxation program on college students' social-emotional competence, personal and professional development. Participants: Twenty female college students participated.
- Trial name
- NCT05694468
- Testing
- Psychomotor Relaxation
- Where
- Portugal
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Évora
Abdominal Surgery
Development of a Patient-Reported Outcome Measure to Assess Recovery After Abdominal Surgery
As surgery enters the era of value-based care, it is advocated that postoperative recovery be measured using patient-reported outcomes (PROs) as they provide a mean to incorporate the patient's perspectives and experiences into…
- Trial name
- NCT03461497
- Where
- 7 sites in United States, Brazil and 3 more
- Volunteers
- 530 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Cortical Excitability, Brain Stimulation
Cortical Excitability and Role of Non Invasive Brain Stimulation in ADHD and AUTISM
This double-blind, randomized, sham-controlled clinical trial will evaluate the effects of repetitive transcranial magnetic stimulation (rTMS) on children and adolescents with attention-deficit/hyperactivity disorder (ADHD) or…
- Conditions
- Cortical Excitability, Brain Stimulation, ADHD, Autism
- Trial name
- NCT07315217
- Testing
- Active repetitive transcranial magnetic stimulation (rTMS)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Breast Cancer
Xpress Digital Mammography System Images for Computer Aided Detection Development
The primary objective of this study is to acquire digital mammography images produced by the Xpress Digital Mammography System in order to develop Computer Aided Detection software and systems.
- Trial name
- NCT01061138
- Where
- 5 sites in United States
- Volunteers
- 597 people, healthy volunteers welcome
- Sponsor
- Konica Minolta Medical Imaging, USA
Autism Spectrum Disorder
Translating Evidence-based Interventions for ASD: Multi-Level Implementation Strategy
The purpose of this study is to test the effectiveness of the "Translating Evidence-based Interventions (EBI) for ASD: Multi-Level Implementation Strategy" (TEAMS) model on provider-level implementation outcomes when used to…
- Trial name
- TEAMS (NCT03380078)
- Testing
- Teams Leadership Institute (TLI), Motivational Enhancement (TIPS for Training), Classroom Pivotal Response Teaching (CPRT)
- Where
- 3 sites in United States
- Volunteers
- 1,206 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Exposures Associated With Pregnancy, Delivery and Lactation
Impact of Perinatal Exposure to Non-caloric Sweeteners on Food Preferences and Weight Gain in the First Year of Life
During last years, non-caloric sweeteners (NCSs) have been increasingly incorporated into foodstuffs in replacement of sucrose in Chile.
- Trial name
- NCT03972176
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- University of Chile
Neurodevelopmental Disorders, Autism Spectrum Disorder
Early Recognition and Intervention in Siblings at High-risk for Neurodevelopmental Disorder
H1The primary goal of this intervention study is to learn if very early parent-mediated intervention in children at risk for neurodevelopmental disorders in the first year of life can be implemented in routine care, positively…
- Trial name
- ERI-SIBS (NCT06512649)
- Testing
- Early intervention, Active monitoring
- Where
- Italy
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Autism Spectrum Disorder, Asperger Disorder
Understanding the Effects of Intervention on the Brain in Autism
This study examines how the PEERS (Laugeson \& Frankel, 2010; Laugeson, 2016) social-behavioral intervention affects social relationships and brain development and function in autistic preschoolers, adolescents, and young adults.
- Conditions
- Autism Spectrum Disorder, Asperger Disorder, PDD-NOS, Autism
- Trial name
- NCT02680015
- Testing
- PEERS
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Marquette University
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