Clinical trials: Desflurane
Delirium, Postoperative Cognitive Dysfunction
Impact of Desflurane and Sevoflurane on Postoperative Delirium in Elderly Patients
Advanced age is a consistent risk factor for the incidence of postoperative cognitive decline, which is associated with longer hospital stays, decreased quality of life, and increased mortality.
- Trial name
- NCT06176144
- Testing
- Desflurane, Sevoflurane
- Where
- China
- Volunteers
- 890 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Ear Deformities, Acquired
The Effect of General Anesthesia on the Middle Ear Pressure
The investigators aimed to examine the effect of sevoflurane and desflurane, agents used in patients who do not have any ear pathology and undergo surgery under general anesthesia, on the MEP.
- Trial name
- NCT03100604
- Testing
- desflurane,, Sevoflurane
- Volunteers
- 50 people
- Sponsor
- Trakya University
Status; Splenectomy
Effects of Desflurane Versus Propofol on Hemostasis During Splenectomy
The aim of this prospective randomized study is to evaluate the perioperative effects of inhalational anesthesia (desflurane) and intravenous anesthesia (propofol) on hemostasis in patients undergoing splenectomy with liver…
- Trial name
- NCT02079064
- Testing
- Desflurane, Propofol
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Theodor Bilharz Research Institute
Quality of Recovery, Anesthesia Recovery Period
Comparing Quality of Recovery Between Desflurane & Isoflurane in Eye Surgery Patients at Dr George Mukhari Acad Hospital
Recovery after surgery and anaesthesia has traditionally been assessed with objective measures including time to awakening, time to regaining airway reflexes, duration of stay in the recovery room and/or hospital, and incidence…
- Trial name
- DIQoR (NCT04188314)
- Testing
- Desflurane, Isoflurane
- Where
- South Africa
- Volunteers
- 170 people
- Sponsor
- Sefako Makgatho Health Sciences University
Agitation
ED50 of Dexmedetomidine to Prevent Emergence Agitation in Children
There are several recommended doses of dexmedetomidine for prevention of emergence agitation in children. In this study, the investigators examine ED50 in prevention of emergence agitation after tonsillectomy or adenoidectomy in…
- Trial name
- NCT01374737
- Testing
- Dexmedetomidine
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- Seoul National University Hospital
Atelectasis, Nasal Septal Deviation
Fresh Gas Flow Rate and Perioperative Lung Aeration Assessed by Lung Ultrasound in Septoplasty
This prospective, single-center observational cohort study evaluated the association between fresh gas flow rate during inhalational anesthesia and perioperative changes in lung aeration in adults undergoing elective surgery for…
- Trial name
- NCT07758517
- Testing
- Fresh Gas Flow Rate of 1 L/min, Fresh Gas Flow Rate of 3 L/min
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Postoperative Cognitive Dysfunction
LINC01844 as a Diagnostic Biomarker for POCD in Elderly Patients
Postoperative cognitive dysfunction (POCD) is a common complication after surgery that is associated with more adverse events and death.
- Trial name
- NCT06387836
- Testing
- Isoflurane 0.8 MAC, Desflurane 0.8MAC
- Where
- China
- Volunteers
- 85 people
- Sponsor
- Shanghai Zhongshan Hospital
Postoperative Complications
Effect of Desflurane Versus Sevoflurane With Recent Bio-markers on Renal and Hepatic Functions
Studying the effects of both inhalational anesthetics desflurane and sevoflurane on hepatic integrity and renal function, guided by recent blood and urine biomarkers in patients undergoing laparoscopic cholecystectomy surgery.
- Trial name
- NCT05027191
- Testing
- Neutrophil Gelatinase-Associated Lipocalin (NGAL), Desflurane, Sevoflurane
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Theodor Bilharz Research Institute
DNA Damage, Anesthesia
Comparison of the Genotoxicity of Desflurane and Propofol
The purpose of this study is to evaluate if the anesthetics propofol and desflurane can damage DNA according to comet essay in patients submitted to lumbar disc surgery.
- Trial name
- NCT05185167
- Testing
- Anesthetics, General Desflurane Maintenance, Anesthetics, General Propofol Maintenance
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Muğla Sıtkı Koçman University
Obesity, Bariatric Surgery
Swap Anesthetic Versus Continuous Desflurane in Adults Undergoing Bariatric Surgery
This randomized, parallel-group, non-inferiority clinical trial aims to evaluate whether an anesthetic swap strategy consisting of sevoflurane followed by desflurane 30 minutes before the end of surgery is non-inferior to…
- Trial name
- SWAP (NCT07748247)
- Testing
- Desflurane, Sevoflurane-Desflurane
- Where
- Chile
- Volunteers
- 82 people
- Sponsor
- Clínica Dávila
Hepatectomy
Propofol/Dexmedetomidine Versus Desflurane Effects on Post Hepatectomy Hepatocellular Injury
This study will compare the effects of propofol/dexmedetomidine versus desflurane for maintenance of general anesthesia on hepatocellular injury in patients undergoing partial hepatectomy.
- Trial name
- NCT05246371
- Testing
- Propofol, dexmedetomidine, Desflurane
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Non-small Cell Lung Cancer, Surgery
Anesthesia and Non-small Cell Lung Cancer Recurrence
There has been ongoing debate about the relationship between cancer recurrence and anesthetic management. Therefore, the investigators will test the hypothesis that the recurrence free survival (RFS) after curative resection of…
- Conditions
- Non-small Cell Lung Cancer, Surgery, Anesthesia
- Trial name
- GASTIVA (NCT06330038)
- Testing
- Propofol, Inhaled anesthetics
- Where
- South Korea
- Volunteers
- 5,384 people
- Sponsor
- Samsung Medical Center
Remimazolam, Desflurane
Remimazolam vs Desflurane for General Anesthesia for Ablation of Arrhythmia
In anesthesia for ablation for cardiac arrhythmias, abrupt hemodynamic changes or fatal arrhythmias can be seen frequently. Remimazolam is a novel ultra-short acting benzodiazepine that provides good hemodynamic stability…
- Conditions
- Remimazolam, Desflurane, Cryoablation, Arrhythmia
- Trial name
- NCT05486377
- Testing
- Remimazolam besylate
- Where
- South Korea
- Volunteers
- 96 people
- Sponsor
- Seoul National University Bundang Hospital
PD - Parkinson's Disease, Dexmedetomidine
Choice of Anesthesia in Microelectrode Recording Guided Deep Brain Stimulation for Parkinson's Disease
Subthalamic nucleus (STN)-deep brain stimulation (DBS) under general anesthesia has been applied to PD patients who cannot tolerate awake surgery, but general anesthesia will affect the electrical signal in microelectrode…
- Conditions
- PD - Parkinson's Disease, Dexmedetomidine, Desflurane, Deep Brain Stimulation
- Trial name
- CHAMPION (NCT05550714)
- Testing
- general anesthesia, Conscious sedation
- Where
- China
- Volunteers
- 188 people
- Sponsor
- Beijing Tiantan Hospital
Opioid Use, Bariatric Surgery Candidate
Evaluation of the Stress Response in Anesthesia Use Inhalation Anesthetic (Desflurane) Versus TIVA for Bariatric Surgery
The goal of this clinical trial is to compare the effects of Opioid Free Anesthesia (OFA) with and without volatile anesthetics (in this case desflurane) in patients undergoing bariatric surgery.
- Conditions
- Opioid Use, Bariatric Surgery Candidate, TCI Eleveld, Obesity
- Trial name
- NCT07568938
- Testing
- opioid free anesthesia, Opiod Free Anesthesia with TCI ELEVELD
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- G.Gennimatas General Hospital
Lung Volume Reduction Surgery
Effects of Desflurane and Propofol During Lung Volume Reduction Surgery
Patients presenting for lung volume reduction are very high risk patients and it is important they receive the best anesthetic available. This study aims to answer which is the best anesthetic for managing such cases.
- Trial name
- NCT04226625
- Testing
- Propofol, Desflurane
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Columbia University
General Anesthesia
Comparison of Desflurane and Propofol on Quality of Recovery in Patients Undergoing Robotic or Laparoscopic Gastrectomy
The purpose of this study is to investigate whether propofol can improve quality of recovery compared to desflurane in patients undergoing robotic or laparoscopic gastrectomy.
- Trial name
- NCT02515968
- Testing
- Desflurane, Propofol
- Sponsor
- Yonsei University
Anesthesia
1-1-12 Wash-in for Desflurane Low Flow Anesthesia
We propose a new wash-in technique for desflurane low flow anesthesia with fresh gas flow of O2:N2O 1:1 L/min with desfluraene 12%.
- Trial name
- NCT02013882
- Testing
- 1-1-12 wash-in
- Where
- Thailand
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Postoperative Pain
Pain After Laparoscopic Cholecystectomy
To the investigators' knowledge, no study has looked at differences in postoperative pain when comparing maintenance of anesthesia with isoflurane, desflurane, sevoflurane, and propofol in laparoscopic cholecystectomy.
- Trial name
- NCT00983918
- Testing
- Desflurane, Sevoflurane, Isoflurane
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Baylor College of Medicine
Emergence Agitation
Comparison of Emergence Agitation Between Sevoflurane and Desflurane Anesthesia After Orthognathic Surgery
Emergence agitation is a major concern in patients undergoing orthognathic surgery. The patients may experience the sense of suffocation during emergence due to nasotracheal intubation and orofacial edema.
- Trial name
- NCT01878656
- Testing
- Sevoflurane, Desflurane
- Where
- South Korea
- Volunteers
- 144 people
- Sponsor
- Chung-Ang University Hospital