Clinical trials: Depth of Anesthesia Monitoring
Heart Valve Diseases
Depth of Anesthesia in Cardiac Surgery
The aim of our study was to evaluate the significance of monitoring anesthetic depth for the conduct of anesthesia and the early postoperative period in patients subjected to surgical correction of combined valvular disorders.
- Trial name
- NCT01524354
- Testing
- maintenance of anesthesia
- Volunteers
- 28 people
- Sponsor
- Northern State Medical University
Retrograde Intrarenal Surgery (RIRS), Urolithiasis
Evaluation of Sevoflurane Consumption During Initial Phase of Minimal-Flow Anesthesia in Retrograde Intrarenal Surgery
This study aimed to compare the effects of minimal-flow (0.5 L/min) and low-flow (1.0 L/min) sevoflurane anesthesia on agent consumption, anesthetic depth, and cardiorespiratory safety during retrograde intrarenal surgery (RIRS).
- Conditions
- Retrograde Intrarenal Surgery (RIRS), Urolithiasis, Minimal-flow Anesthesia, Sevoflurane
- Trial name
- SEVOMIN-RIRS (NCT07248917)
- Testing
- Sevoflurane Anesthesia with Minimal-flow, Sevoflurane Anesthesia with Low-flow
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Aging, Inflammation
Macrophage/Monocyte Driven Inflammation and Anesthetic Sensitivity in Aging
The goal of this observational study is to determine whether macrophage/monocyte mediated inflammatory signaling contributes to reduced anesthetic requirements in older adults undergoing major abdominal surgery.
- Conditions
- Aging, Inflammation, Blood-Brain Barrier Permeability, Anesthesia Brain Monitor
- Trial name
- MACRO-AGE (NCT07372417)
- Where
- Chile
- Volunteers
- 60 people
- Sponsor
- University of Chile
Monitoring of Depth of Anesthesia, AAI Index
Monitoring of Adequate Course of General Anesthesia
Clinical monitoring is the most common method of adjustment of the appropriate level of general anesthesia. However, the episodes of intraoperative awareness are still reported, suggesting that clinical observations may not be…
- Trial name
- MoDA (NCT03331692)
- Testing
- monitoring of the proper level of general anesthesia
- Where
- Poland
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Military Institute od Medicine National Research Institute
Cardiopulmonary Bypass, Hypothermia; Anesthesia
Effect of Hypothermia on BIS and PSI Correlation During Cardiopulmonary Bypass
The goal of this observational study is to evaluate whether hypothermia affects the relationship between electroencephalography-derived indices during cardiac surgery in adult patients undergoing cardiopulmonary bypass.
- Conditions
- Cardiopulmonary Bypass, Hypothermia; Anesthesia, Depth of Anesthesia Monitoring
- Trial name
- NCT07508579
- Testing
- Simultaneous BIS and PSI Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sakarya University
Infertility, Female, Anesthesia Awareness
Preoperative Anxiety at Oocyte Retrieval
This study evaluated the effects of preoperative anxiety and dosage of anesthesia on IVF success. Half of participants according to the recorded Beck's Anxiety Inventory (BAI) score: a low-anxiety group, while the other half…
- Conditions
- Infertility, Female, Anesthesia Awareness, Anxiety State
- Trial name
- NCT03134651
- Testing
- Monitoring brain function, propofol
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Trakya University
Anesthesia, Emergence Delirium
The Effect of Anesthesia Depth Monitoring on Emergence Delirium in Pediatrics
Some changes in the patient's cognitive state are observed during the recovery period from general anesthesia. This period of behavioral dysregulation has been called emergence agitation (EA) and emergence delirium (ED).
- Conditions
- Anesthesia, Emergence Delirium, Anesthesia Awareness, Behavior Child Problems
- Trial name
- NCT06323616
- Testing
- MAC adjustment to PSI between 25 and 50
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Istanbul University
Rhinoplasty, Depth of Anesthesia
Processed EEG Monitoring During Controlled Hypotension in Patients Undergoing Rhinoplasty
This prospective observational study evaluates intraoperative processed electroencephalography parameters in adult patients undergoing elective rhinoplasty under total intravenous anesthesia with controlled hypotension.
- Conditions
- Rhinoplasty, Depth of Anesthesia, Surgical Bleeding, Postoperative Recovery
- Trial name
- NCT07671781
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Gazi University
Spine Surgery
Motor Evoked Potentials and SedLine
To determine if using usual clinical practice plus a depth of anesthesia monitor, SedLine, to guide anesthetic administration improves the quality and ease of MEP monitoring in patients undergoing corrective spinal procedures.
- Trial name
- NCT00805844
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of California, San Francisco
Hypnotic; Withdrawal State With Delirium, Neurological Disorder
Efficacy of BIS Monitoring in Deep Hypnotic State
Determining the efficacy of the BIS monitor in monitoring deep hypnotic states as well as intra- and post-operative outcomes in neurosurgery patients
- Conditions
- Hypnotic; Withdrawal State With Delirium, Neurological Disorder, Postoperative Delirium, Postoperative Confusion
- Trial name
- NCT06177847
- Testing
- BIS
- Volunteers
- 50 people
- Sponsor
- Universitas Indonesia
Anesthesia, General
Monitoring of Anesthetic Depth and EEG Band Power Using PLE (Phase Lag Entropy) During Propofol Anesthesia
The evaluation of the anesthetic depth monitoring using PLE (Phase Lag Entropy) during propofol anesthesia
- Trial name
- PLE (NCT03299621)
- Testing
- PLE (Phase Lag Entropy), Muscle Relaxant
- Where
- 2 sites in South Korea
- Volunteers
- 35 people
- Sponsor
- Korea University Anam Hospital
Cardiac Arrythmias, Anesthesia
Minimally Invasive Hemodynamic Monitoring in Cardiac Ablation
This prospective observational clinical study aims to evaluate the clinical utility of Pressure Recording Analytical Method (PRAM)-based minimally invasive hemodynamic monitoring in patients undergoing cardiac ablation…
- Trial name
- NCT07603765
- Testing
- Minimally invasive hemodynamic monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Istanbul University - Cerrahpasa
BIS-EEG, PSI
Comparison of the Factors Affecting PSI and BIS Values in Monitoring Anesthetic Depth During Open-Heart Surgery
Measurement of anesthetic depth has long been a subject of investigation, aiming to titrate anesthetic agents appropriately and to prevent intraoperative awareness and consciousness.
- Conditions
- BIS-EEG, PSI, Open Heart Surgery, Anesthesia Depth Monitoring
- Trial name
- NCT07042906
- Testing
- anesthesia depth monitorizing, awareness
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Kocaeli University
Awareness During General Anesthesia
Is Density Spectral Array Display Along With Bispectral Index Superior to the Display of Bispectral Index Alone
A study to evaluate the use of density spectral array display in comparison with Bispectral index in a clinical setting.
- Trial name
- DSA-Light (NCT07232160)
- Testing
- Depth of anesthesia monitoring using processed EEG
- Where
- Australia
- Volunteers
- 70 people
- Sponsor
- The University of Queensland
Nociception
Quantitative Consciousness Index Monitoring (qNOX) of Sedation During Endoscopy
Nociception is the encoding and processing of noxious stimulation and is considered an objective indicator for monitoring pain. Currently, a new clinically-applied medical-engineering integrated monitoring device for noxious…
- Trial name
- NCT06777589
- Testing
- Monitoring of anesthesia depth
- Where
- China
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Min Su
General Anesthesia
Comparison of Two Electroencephalograms (EEG) Monitors in Patients Undergoing General Intravenous Anesthesia
Quantium Medical Company has an ElectroEncephalograph-based (EEG-based) algorithm with two outputs: qCON for unconsciousness and qNOX for anti-nociception.
- Trial name
- Bis-qCON-IV (NCT03753217)
- Testing
- qCON Monitor
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Hopital Foch
Postoperative Delirium, Cognitive Impairment
Predictive Efficacy of Ratio of Median Frequency to Spectral Edge Frequency Used in the Depth of Anaesthesia Monitoring on Post-operative Cognitive Functions
The primary objective of this observational study is to evaluate the effectiveness of preoperative anaesthesia depth monitoring parameters in predicting postoperative cognitive functions in non-cardiac adult patients.
- Trial name
- NCT06644209
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people
- Sponsor
- Ankara University
The Association of Postoperative Cognitive Dysfunction With Glymphatic Function and Neuroinflammation, The Association of Postoperative Cognitive Dysfunction With CSF Metabolomic Change
CSF Metabolomics and Glymphatic Function in Patients Receiving VP- Shunt Surgery.
In this randomized control study, the investigators intended to evaluate the influence of different anesthetics on postoperative cognitive dysfunction, neuroinflammation, CSF metabolomics, and glymphatic function in patients with…
- Trial name
- NCT06005363
- Testing
- Dexmedetomidine, anesthesia depth monitoring
- Where
- Taiwan
- Volunteers
- 48 people
- Sponsor
- Chang Gung Memorial Hospital
Low Flow Anesthesia
Low-Flow Anesthesia Without Wash-in: Effects on Oxygenation and Depth of Anesthesia
This study aims to evaluate whether adjusting the fresh gas flow rate to low-flow immediately after intubation, without performing a wash-in, is a reliable approach with respect to depth of anesthesia and oxygenation.
- Trial name
- NCT07534839
- Testing
- Initiation of low-flow anesthesia without wash-in following intubation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Erzincan Binali Yildirim Universitesi
Movement Disorders, Depth of Anesthesia Monitors
BIS and Entropy in Deep Brain Simulation
The main objective of the study is to determine whether depth of anesthesia (DOA) monitoring such as Bispectral Index (BIS) and entropy are accurate in patients with neuro-psychological conditions such as Parkinson's disease by…
- Trial name
- NCT02386995
- Testing
- BIS monitor, Entropy monitor
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University Health Network, Toronto