Clinical trials: Depressive Symptoms, Postpartum
Post Partum Depression
Risk of Maternal Depression From 1 Year to 4 Years Postpartum in Yvelines
This observational study aims to estimate the prevalence of women from 1 to 4 years postpartum in Yvelines, who are suspected to suffer from postpartum depression, using the Edinburg Post natal Depression Scale (EPDS) and the…
- Trial name
- DeTaPoP (NCT06042972)
- Testing
- Questionnaire including Edinburgh postnatal depression scale, Patient Health Questionnaire 2 and background variables
- Where
- France
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Centre Médical Porte Verte
Perinatal Depression, Post Partum Depression
Characterizing the Neural Substrates of Irritability in Women: an Experimental Neuroendocrine Model
The proposed study involves experimentally manipulating reproductive hormones in nonpregnant, euthymic women to create a scaled down version of the changes that occur during pregnancy and the postpartum period.
- Conditions
- Perinatal Depression, Post Partum Depression, Depression, Postpartum, Depression
- Trial name
- NCT04051320
- Testing
- Leuprolide Acetate 3.75 MG/ML, Estradiol 2 Mg tablet, Micronized progesterone
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Premature, Low Birth Weight
Effect of Kangaroo Baby Massage on Mother-infant Interaction at Home
The objective of this randomized clinical trial will determine the effectiveness of nursing intervention (Kangaroo Baby Massage) on the interaction between mothers and premature, low birth weight infants at home The dyad mother…
- Conditions
- Premature, Low Birth Weight, Mother-Infant Interaction, Gain, Weight
- Trial name
- KBM (NCT04908332)
- Testing
- Kangaroo Baby Massage
- Where
- Colombia
- Volunteers
- 68 people
- Sponsor
- Universidad Nacional de Colombia
Postpartum Depression (PPD)
Moringa Oleifera and Phoenix Dactylifera L. Effects on Cortisol and Breast Milk in Postpartum Depression
Postpartum depression affects 10-20% of new mothers globally, potentially disrupting breast milk production. This study aimed to provide valuable insights into effective interventions to improve the health and well-being of…
- Trial name
- NCT07337512
- Testing
- Phoenix dactylifera L, Moringa oleifera
- Where
- Indonesia
- Volunteers
- 363 people, healthy volunteers welcome
- Sponsor
- Melania Asi
Overweight and Obesity, Depression, Postpartum
Madres Para la Salud (Mothers for Health)
The purpose of "Madres Para la Salud" [Mothers for Their Health] is to see how support and encouragement can help women to make positive changes in their health.
- Conditions
- Overweight and Obesity, Depression, Postpartum, Mother (Person)
- Trial name
- NCT01908959
- Testing
- Madres para la Salud
- Where
- United States
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Postpartum Depression
The ROSE Scale-up Study: Informing a Decision About ROSE as Universal PPD Prevention
The Reach Out, Stand Strong, Essentials for New Mothers (ROSE) program is an evidence-based intervention that prevents half of cases of postpartum depression and was one of two interventions recommended by the US Preventive…
- Trial name
- ROSES-II (NCT05700760)
- Testing
- ROSE (Reach Out, Stay Strong, Essentials for mothers of newborns), Enhanced Care as Usual (CAU)
- Where
- United States
- Volunteers
- 2,320 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Postpartum Depression (PPD)
A Mobile Application for Early Detection and Symptoms Trajectories of Postpartum Depression Using Ecological Momentary Assessment (EMA)
This pilot study will recruit 120 perinatal pregnant women and follow them up for 6 months. Both momentary and retrospective assessments of emotional well-being and psychosocial factors will be conducted on a mobile application.
- Trial name
- EMA For PND (NCT07382336)
- Testing
- Ecological momentary assessment and retrospective assessment
- Where
- Hong Kong
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Postpartum Depression, Parenting
Social Media Intervention for Postpartum Depression
This study is intended to compare the acceptability and feasibility and explore outcomes related to two different formats of a parenting program for mothers with postpartum depressive symptoms.
- Trial name
- NCT02355067
- Testing
- Social Media Intervention, Traditional In-Person Intervention
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Depression, Postpartum
Cerebral Synchronization Between Mothers and Their Newborns During Breastfeeding
Different reciprocal positions of mother and newborn during breastfeeding may be adopted. Other than the one derived from UNICEF guidelines, or standard position, an approach called biological nurturing has been recently…
- Trial name
- NCT05821569
- Testing
- Standard approach, Biological nurturing
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Burlo Garofolo
Perinatal Depression, Postpartum Depression
A Pilot Randomized Trial of Video-based Family Therapy for Depressed Home Visited Mothers
Depressed mothers (pregnant and post-delivery) make up a significant portion of Maternal, Infant, and Early Childhood Home Visiting (MIECHV) clients.
- Conditions
- Perinatal Depression, Postpartum Depression, Family Conflict
- Trial name
- NCT04741776
- Testing
- Resilience Enhancement Skills Training, Problem-Solving Individual Therapy
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Microbial Colonization
Comparing Impacts of Donor Human Milk to Formula Supplementation on the Gut Microbiome of Full-term Infants
The goal of this pilot randomized controlled trial (RCT) is to examine donor human milk (DHM) as a clinical intervention targeted at achieving beneficial microbiome signatures in full-term infants who are exposed to intrapartum…
- Trial name
- PPDHM (NCT05815433)
- Testing
- Donor Human Milk - Nutritional Replacement
- Where
- Canada
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Depression, Unipolar, Pain, Postoperative
Maternal Mindfulness: Depression and Postpartum Pain
This phase I clinical trial tests the feasibility and safety of a self-guided, mobile mindfulness-based intervention to reduce post-cesarean pain and prevent postpartum depression.
- Trial name
- MaMiDaPP (NCT05400382)
- Testing
- Mindfulness
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Depression, Depression, Postpartum
TrueBlue Clinical Study - Investigating the Use of a Mobile Phone App TrueBlue for Monitoring Depression and Anxiety
This trial will assess the safety, feasibility, acceptability, usability and agreement with validated scales of an automated mood monitoring App (TrueBlue), in adult, perinatal participants (recruited between 12 weeks of…
- Conditions
- Depression, Depression, Postpartum, Anxiety in Pregnancy, Anxiety
- Trial name
- NCT06364488
- Testing
- TrueBlue App
- Where
- 2 sites in United Kingdom
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- BlueSkeye AI
Postnatal Depression
Home-based Transcranial Direct Current Stimulation in Postpartum Depression: the Feasibility Study and Pilot Study
Postpartum Depression (PPD) is a Major Depressive (MD) Disorder occurring within the 12 months after delivery with negative effects to the mother, the child and the family and an estimated prevalence in Europe of 10-15%.
- Trial name
- 4MUMs (NCT05046405)
- Testing
- Transcranial Direct Current Stimulation
- Volunteers
- 50 people
- Sponsor
- Ana Ganho Ávila
Postpartum Depression
Can Oxytocin Level Predict Postpartum Depression?
The goal of this research study is to understand the relationship between the hormone oxytocin and postpartum mood.
- Trial name
- NCT02020148
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Postoperative Pain, Cesarean Section Surgery
Analysis of the Incidence and Risk Factors of Chronic Pain After Cesarean Section
Persistent postoperative pain is a globally recognized issue that deserves attention. Cesarean section is one of the surgeries that may cause persistent postoperative pain.
- Trial name
- NCT06704490
- Testing
- Cesarean section
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Huazhong University of Science and Technology
Postpartum Depression
Early Diagnosis of PPD Through Self-portraits
the target of the research is development of a predictive tool for early identification of women which are at higher risk for development of postpartum depression.
- Trial name
- ppd (NCT03791021)
- Testing
- draw a person (DAP), Edinburgh Postnatal Depression Scale (EPDS), Beck Depression Inventory- II (BDI-II)
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Sheba Medical Center
Postpartum Depression (PPD), Cardiac Event
Living Healthy for Moms RCT
LHMoms is a novel integrated care intervention that focuses intensively on care continuity and community-to-healthcare linkages for postpartum birthing individuals.
- Trial name
- LHMoms (NCT06666400)
- Testing
- LHMoms Intervention, No intervention
- Where
- 4 sites in United States
- Volunteers
- 21 people
- Sponsor
- Columbia University
Depression, Postpartum, Pregnancy
Labor Pain and Postpartum Behavioral Health Outcomes Study
In this pilot prospective longitudinal observational study, women who are pregnant and who will be experiencing childbirth for the first time will be recruited at the third trimester and observed longitudinally for psychiatric…
- Conditions
- Depression, Postpartum, Pregnancy, Child Development, Pain
- Trial name
- LPPD (NCT02692404)
- Where
- 2 sites in United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Depression, Clinical Depression
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Depression
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records
- Conditions
- Depression, Clinical Depression, Depression, Anxiety, Depression, Postpartum
- Trial name
- NCT04211467
- Testing
- No Intervention
- Where
- United States
- Sponsor
- ProgenaBiome