Clinical trials: Depressive Symptoms, Postpartum
Postpartum Depression, Infant Development
Social Circumstances, Parenting Techniques, and Infant Development
1. Investigators aim to assess a novel behavioral intervention (currently approved in Protocol #6285) behavioral intervention that promotes maternally-mediated behavioral changes in young infants to reduce the risk of postpartum…
- Conditions
- Postpartum Depression, Infant Development, Rhythm; Sleep
- Trial name
- NCT02121496
- Testing
- Resources for Postpartum Parenting
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Maternal Health, Pregnancy
Understanding the Role of Doulas in Supporting People With PMADs
Detailed Description The doula-led intervention developed during the first phase of this project will be pilot tested for feasibility.
- Conditions
- Maternal Health, Pregnancy, Delivery, Obstetric, Self Efficacy
- Trial name
- NCT05763537
- Testing
- Standard Doula Care Plus PMAD Intervention, Standard Doula Care
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Montana
Depression, Postpartum
The Impact of Creative Interventions on Symptoms of Postnatal Depression
Post-natal depression (PND) is anticipated to affect 12.9% of new mothers with at least 75,000 cases per year in the UK alone. However, despite this, there is currently a worrying lack of support for new mothers, with data…
- Trial name
- NCT02526407
- Testing
- Singing, Group play
- Where
- 2 sites in United Kingdom
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Royal College of Music
Pain, Postoperative, Depression, Postpartum
Ketamine Tolerated Dose for Postpartum Depression and Pain After Cesarean Delivery (PREPARE 1)
The purpose of this study is to identify a tolerable dose for postpartum ketamine infusion using a maximum tolerated dose (MTD) 3+3 design.
- Trial name
- NCT05907213
- Testing
- Ketamine (Ketalar) Dose Level 1, Ketamine (Ketalar) Dose Level 2, Ketamine (Ketalar) Dose Level 3
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Grace Lim, MD, MS
Depression, Postpartum, Depression, Unipolar
Tracking Depression Symptoms With a Health Chatbot
The goal of this research is to bridge a significant "effectiveness" gap in the treatment of depression. The investigators have developed a chatbot which will assist in performing measurement-based care (MBC) via Facebook…
- Trial name
- NCT03990389
- Testing
- Chatbot Intervention
- Where
- 2 sites in United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Postpartum Depression (PPD)
A Mobile Application for Early Detection and Symptoms Trajectories of Postpartum Depression Using Ecological Momentary Assessment (EMA)
This pilot study will recruit 120 perinatal pregnant women and follow them up for 6 months. Both momentary and retrospective assessments of emotional well-being and psychosocial factors will be conducted on a mobile application.
- Trial name
- EMA For PND (NCT07382336)
- Testing
- Ecological momentary assessment and retrospective assessment
- Where
- Hong Kong
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Overweight and Obesity, Depression, Postpartum
Madres Para la Salud (Mothers for Health)
The purpose of "Madres Para la Salud" [Mothers for Their Health] is to see how support and encouragement can help women to make positive changes in their health.
- Conditions
- Overweight and Obesity, Depression, Postpartum, Mother (Person)
- Trial name
- NCT01908959
- Testing
- Madres para la Salud
- Where
- United States
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Depression, Depressive Disorder, Major
The Feasibility, Usability and Satisfaction of an Online Tool for Perinatal Mental Health Problems
With this study the investigators aim to examine through a mixed method study the feasibility, usability and satisfaction with the developed online tool for perinatal mental health problems.
- Conditions
- Depression, Depressive Disorder, Major, Depression, Postpartum, Anxiety
- Trial name
- e-PMG (NCT06035159)
- Testing
- online psychotherapy
- Where
- Belgium
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Postoperative Pain, Cesarean Section
Effects of Nerve Blocks on Pain After Caesarean Section and Postpartum Depression
At the end of your cesarean section surgery, which is started by applying medication to the spinal cavity from your waist, pain medication will be applied between the relevant muscle and its covering from your lower abdomen or…
- Conditions
- Postoperative Pain, Cesarean Section, Postpartum Depression
- Trial name
- NCT06221280
- Testing
- Nerve block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Obstetric Pain, Postpartum Depression
Ketamine to Improve Recovery After Cesarean Delivery - Part 1
The objective of this study is evaluate the breastmilk transfer and pharmacokinetics (Part 1) and effectiveness (Part 2) of a post-cesarean delivery intravenous ketamine bolus-and-infusion strategy, as a preventive analgesic…
- Conditions
- Obstetric Pain, Postpartum Depression, Breastfeeding, Pain, Acute
- Trial name
- KINETIC (NCT04037085)
- Testing
- Ketamine
- Where
- 2 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Grace Lim, MD, MS
Premature Birth, Birth Weight
Fresh RX: NHS 2020
This study is an evaluation of the Fresh Rx: Nourishing Healthy Starts program administered by Operation Food Search, a St. Louis-based nonprofit organization.
- Conditions
- Premature Birth, Birth Weight, Post Partum Depression, Health Care Utilization
- Trial name
- NCT04845230
- Testing
- FreshRx Nourishing Healthy Starts
- Where
- United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Hyperbilirubinemia, Jaundice
Improving Health Outcomes for New Mothers and Babies
Because adherence to postnatal care guidelines across the United States (U.S.) is poor, newborns and mothers often are placed at undue risk for adverse medical and social outcomes.
- Conditions
- Hyperbilirubinemia, Jaundice, Dehydration, Postpartum Depression
- Trial name
- NCT00360204
- Testing
- Home Nurse Visit
- Where
- 2 sites in United States
- Volunteers
- 1,154 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Postpartum Depression (PPD), Postpartum Anxiety
Investigation of TVNS Administration on Postpartum Mental Health
The aim of the study is to explore whether transcutaneous vagus nerve stimulation (tVNS) may be effective in preventing mood swings and depressive symptoms in the postpartum phase, as well as serving as a supplementary…
- Conditions
- Postpartum Depression (PPD), Postpartum Anxiety, Postpartum Sadness, Postpartum Blues
- Trial name
- NCT06682689
- Testing
- transcutaneous vagus nerve stimulation
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Depression, Postpartum, Stress, Psychological
MAMA NO STRESS Project. The Effects of the "HAPPY MAMA" Intervention
This study evaluates the effects of a postpartum intervention in increasing the maternal well-being and self-efficacy of Italian women in the first one to six months after childbirth, as well as in reducing postpartum depression…
- Conditions
- Depression, Postpartum, Stress, Psychological, Postpartum Sadness, Self Efficacy
- Trial name
- NCT04093791
- Testing
- Collective Intervention "G", Individual Intervention "I"
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Postpartum Urinary Incontinence, Postpartum Depression (PPD)
Prenatal Exercise Including Perineal Massage and Maternal-Neonatal Outcomes
The study is divided into three phases: Phase 1: Baseline survey to obtain an overall understanding of the current situation of voluntary participation in prenatal perineal massage.
- Conditions
- Postpartum Urinary Incontinence, Postpartum Depression (PPD), Neonatal Complications, Gestational Diabetes
- Trial name
- PEPM-RCT (NCT07314502)
- Testing
- Supervised prenatal exercise including antenatal perineal massage
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- South China Normal University
Premature Birth, Low Birth Weight
Pilot Trial of CenteringPregnancy With Mindfulness Skills
In the U.S., rates of preterm birth and low birth weight have increased over the past 30 years. Poor birth outcomes are especially high among racial/ethnic minority populations.
- Conditions
- Premature Birth, Low Birth Weight, Postpartum Depression
- Trial name
- NCT01646463
- Testing
- CenteringPregnancy, CenteringPregnancy with Mindfulness Skills
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Anxiety and Depression, Postpartum Depression
Virtual Reality Biofeedback for Postpartum Anxiety and Depression
The purpose of this study is to test patient feasibility and acceptability of virtual reality biofeedback program in postpartum women for anxiety and depression outcomes.
- Conditions
- Anxiety and Depression, Postpartum Depression, Pregnancy Related
- Trial name
- VITALISE (NCT04925765)
- Testing
- Virtual Reality Biofeedback Session
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Grace Lim, MD, MS
Depression, Depression, Postpartum
Chronobiology, Sleep Related Risk Factors and Light Therapy in Perinatal Depression: the Life-ON Project
In a 3 years longitudinal, observational, multicentre study, about 500 women will be recruited and followed-up from early pregnancy (10-15 gestational week) until 12 months after delivery.
- Conditions
- Depression, Depression, Postpartum, Depressive Disorder, Depressive Disorder, Major
- Trial name
- NCT02664467
- Testing
- Philips EnergyUp EnergyLight HF3419/01
- Where
- Switzerland
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Ospedale Regionale di Lugano
Postpartum Depression
The ROSE Scale-up Study: Informing a Decision About ROSE as Universal PPD Prevention
The Reach Out, Stand Strong, Essentials for New Mothers (ROSE) program is an evidence-based intervention that prevents half of cases of postpartum depression and was one of two interventions recommended by the US Preventive…
- Trial name
- ROSES-II (NCT05700760)
- Testing
- ROSE (Reach Out, Stay Strong, Essentials for mothers of newborns), Enhanced Care as Usual (CAU)
- Where
- United States
- Volunteers
- 2,320 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Depression
Effectiveness of Group Interpersonal Psychotherapy in Treating Women With Prenatal Depression
This study will evaluate the effectiveness of group interpersonal psychotherapy for preventing postpartum depression in pregnant women with depression and for improving healthy outcomes in their babies.
- Trial name
- NCT00633178
- Testing
- Group interpersonal therapy (IPT), Treatment as usual (TAU)
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute