Clinical trials: Depression Mild
Dementia, Mild, Depression
Decision Making Tool for Firearm Storage
This is a one-arm pilot study testing the feasibility and acceptability of a decision aid about safe firearm storage.
- Trial name
- NCT06382194
- Testing
- Decision aid
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Washington
Depression, Post-COVID-19 Syndrome
Evaluation of DEPREXIL in Patients With Clinical Depression Through Psychological and Neuroendocrine Assessment
Clinical depression is a mood disorder that affects people of all ages with symptoms such as sadness, anger or frustration, appetite changes, difficulty concentrating and suicidal thoughts.
- Conditions
- Depression, Post-COVID-19 Syndrome, Depression Mild, Depression Moderate
- Trial name
- NCT06496087
- Testing
- DEPREXIL
- Where
- Colombia
- Volunteers
- 100 people
- Sponsor
- Catalysis SL
Late-Life Depression
Determining Changes in Brain Structure Associated With Symptoms of Late-life Depression
This study will determine the changes in brain structure and function that are responsible for mood and cognition changes that are sometimes associated with late-life depression.
- Trial name
- NCT00178087
- Where
- 2 sites in United States
- Volunteers
- 331 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Major Depressive Disorder
Efficacy of Cognitive Behavioral to Hypnotherapeutic Treatment of Depression
The purpose of the study is to compare the efficacy of an Hypnotherapeutic Treatment of Depression to Cognitive Behavioral Treatment of Depression in patients with mild to moderate Major Depressive Episodes.
- Trial name
- NCT02375308
- Testing
- HDT, ACDT
- Where
- Germany
- Volunteers
- 153 people
- Sponsor
- University Hospital Tuebingen
Concussion, Brain, Treatment
Modulating Exercise Dosage to Improve Concussion Recovery
Aerobic exercise has emerged as an effective treatment to reduce sport-related concussion symptom severity, yet existing work lacks rigor regarding the precise exercise volume and intensity required to elicit therapeutic effects…
- Conditions
- Concussion, Brain, Treatment, Aerobic Exercise, Inflammation
- Trial name
- MEDIC (NCT05434130)
- Testing
- High Dose Exercise
- Where
- 3 sites in United States
- Volunteers
- 178 people
- Sponsor
- University of Colorado, Denver
Impaired Cognition, Depression/Anxiety
Switching From Efavirenz/Atripla to Rilpivirine Among Patients With Neurocognitive or Neuropsychological Side Effects
Despite long-term use in clinical practice, chronic treatment with efavirenz (EFV) has been associated with persistent central nervous system symptoms or mild or even asymptomatic neurocognitive impairment.
- Conditions
- Impaired Cognition, Depression/Anxiety, Poor Quality Sleep, Quality of Life
- Trial name
- SWEAR (NCT02042001)
- Testing
- Immediate switch to TDF/FTC/RPV, Switch to TDF/FTC/RPV after 24 weeks
- Where
- 5 sites in Italy
- Volunteers
- 74 people
- Sponsor
- Azienda Ospedaliera San Gerardo di Monza
Perimenopause, Depression
Effectiveness and Safety of Electro-acupuncture for Mild-to-moderate Perimenopausal Depression
Main objective: to compare the effects of electro-acupuncture and escitalopram oxalate tablets on mild-to-moderate perimenopausal depression, and to evaluate the safety of electroacupuncture stimulation.
- Trial name
- NCT02423694
- Testing
- electro-acupuncture, escitalopram oxalate tablets
- Where
- China
- Volunteers
- 252 people
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
Mild Cognitive Impairment (MCI), Depression
Brain Aging and Treatment Response in Geriatric Depression
The proposed project will evaluate the role of neuroimaging biomarkers of brain aging (i.e., neurodegenerative and vascular brain changes) and mild cognitive impairment in the patterns of treatment response to memantine combined…
- Trial name
- NCT01902004
- Testing
- Escitalopram, Memantine
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- University of California, Los Angeles
Depression Mild, Depression Moderate
Treatment of Depression Using a Mobile Application in the Dominican Republic
The overall objective of this study is to develop a feasible and acceptable mental health app which delivers Cognitive Behavioral Therapy (CBT) for depressed patients in the Dominican Republic.
- Trial name
- NCT04948996
- Testing
- El Buen Consejo Móvil- Group (EBCM-G), El Buen Consejo Móvil- Individual (EBCM-I)
- Where
- 2 sites in United States, Dominican Republic
- Volunteers
- 27 people
- Sponsor
- Northern Illinois University
Dementia, Mild, Depressive Disorder
Dignity Therapy for Patients With Early Dementia and Their Family
Developed by Harvey M. Chochinov in 2005, Dignity Therapy (DT) invites individuals with life-limiting illnesses to reflect on matters of importance to them and compiles them in a narrative document for the patient to share.
- Trial name
- DTD (NCT03692988)
- Testing
- Dignity Therapy
- Where
- Switzerland
- Volunteers
- 54 people
- Sponsor
- University of Zurich
Inflammatory Bowel Diseases, Mild Cognitive Impairment
Cognitive Impairment and Affective Mood Disorders in Patients With IBD
The aim is to evaluate the presence of mild cognitive impairment (MCI) in patients with inflammatory bowel disease (IBD). This will be done by cognitive tests.
- Conditions
- Inflammatory Bowel Diseases, Mild Cognitive Impairment, Depression, Anxiety
- Trial name
- COGN-IBD-1 (NCT05760729)
- Testing
- Cognitive testing
- Where
- 3 sites in Romania
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Depression, Multiple Sclerosis
The Efficacy and Safety of Escitalopram for Depression in Multiple Sclerosis
Emotionally labile, depressed participants with multiple sclerosis treated with escitalopram will have a greater reduction in emotional lability scores and in their psychological distress scores than those who are randomized to…
- Trial name
- NCT00151294
- Testing
- escitalopram oxalate antidepressant
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Weill Medical College of Cornell University
Mild Depressive Disorder Comorbid With Anxiety Disorder
A Clinical Study Evaluating the Efficacy and Safety of CreNeuroS CNS Herbal Nutrition Capsules for Participants With Mild Depressive Disorder Comorbid With Anxiety Disorder
The incidence of Mild Depressive Disorder Comorbid With Anxiety Disorder is dramatically increasing. dietary supplements may show better efficiency and less side effect.Here investigators intend to assess Efficacy and Safety of…
- Trial name
- NCT07295444
- Testing
- A Clinical Study Evaluating the Efficacy and Safety of CreNeuroS CNS Herbal Nutrition Capsules for Participants With Mild Depressive Disorder Comorbid With Anxiety Disorder
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Depression, Anxiety Disorders
Investigating Transcranial Ultrasound as a Potential Intervention for Depression
Depression is the leading cause of disability worldwide. Because a significant number of people with depression do not respond to medication or therapy, alternative treatment options are greatly needed.
- Trial name
- NCT02685488
- Testing
- Transcranial Ultrasound Power
- Volunteers
- 26 people
- Sponsor
- University of Arizona
Specific Learning Disorder, Intellectual Disability, Mild to Moderate
SWELE Program: An Unstructured Outdoor Play With Mindfulness-based Interventions to Promote Mental Health Among Students With Special Education Needs
This is an observational study with the aim of SWELE Programme is to raise mental health knowledge and awareness by implementing a play-based approach on Supporting Wellness in E-Child Learning Environments (SWELE) programme…
- Conditions
- Specific Learning Disorder, Intellectual Disability, Mild to Moderate, Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
- Trial name
- SEN (NCT06112483)
- Testing
- SWELE Programme
- Volunteers
- 1,064 people
- Sponsor
- Chinese University of Hong Kong
Depression and/or Anxiety in the Mild-to-moderate Range
Personalized Need-focused Single Session Intervention
This is a two-site randomized controlled trial, with two goals. First, the investigators aim to demonstrate that single-session interventions for mild-to-moderate anxiety and depression can generate statistically significant…
- Trial name
- NCT05953779
- Testing
- Clinician-administered Need-focused Single Session Intervention
- Where
- 2 sites in United States, Israel
- Volunteers
- 240 people
- Sponsor
- Bar-Ilan University, Israel
Mild Cognitive Impairment (MCI), Dementia
Culturally Familiar Nostalgic VR Cognitive Training for Older Adults
This randomized controlled trial investigates the effects of a nostalgia-based cognitive training intervention delivered via Virtual Reality (VR) on emotional well-being and cognitive functioning among community-dwelling older…
- Conditions
- Mild Cognitive Impairment (MCI), Dementia, Cognitive Decline, Psychological Well-being
- Trial name
- NCT06973551
- Testing
- Brain Health Nostalgic VR Program
- Where
- Taiwan
- Volunteers
- 64 people
- Sponsor
- National Taiwan Normal University
Cognition Function, Mild Depression
Effect of Probiotic on Cognitive Function
The goal of this clinical trial is to learn if daily single-strain probiotic supplementation (Lactobacillus plantarum) works to improve cognitive function and depressive symptoms in Egyptian women aged 50-64 years with mild…
- Trial name
- NCT07776145
- Testing
- Lactobacillus plantarum
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Cairo University
Mild Cognitive Impairment, Major Depressive Disorder, Recurrent, In Remission
Prevention of Alzheimer's Disease With CR Plus tDCS in Mild Cognitive Impairment and Depression (PACt-MD)
This 7-year randomized controlled trial will compare the efficacy of non-invasive brain stimulation (trans-cranial Direct Current Stimulation - tDCS) combined with cognitive remediation (CR) versus sham ("placebo") tDCS combined…
- Conditions
- Mild Cognitive Impairment, Major Depressive Disorder, Recurrent, In Remission, Major Depressive Disorder, Single Episode, in Full Remission
- Trial name
- PACt-MD (NCT02386670)
- Testing
- tDCS + CR
- Where
- 5 sites in Canada
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Traumatic Brain Injury, Concussion, Mild
fMRI-neuronavigated rTMS Treatment for Symptoms of Depression Associated With Concussive TBI in the Military Population
This study aims to investigate the efficacy and tolerability of fMRI-targeted repetitive transcranial magnetic stimulation (rTMS) in the treatment of depressive symptoms in service members with a history of concussive traumatic…
- Conditions
- Traumatic Brain Injury, Concussion, Mild, Depressive Symptoms
- Trial name
- NCT03523507
- Testing
- Active: rTMS
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine