Clinical trials: Depression Mild
Mild Cognitive Impairment
WAVE: AudioVisual Stimulation Enhances Cognitive, Mental and Physical Health in Elderly
The goal of this randomized controlled trial is to 1) carry out a screening of cognitive function, depressive symptoms, agility and functional balance and chronic inflammatory conditions in older adults; 2) analyze the influence…
- Trial name
- NCT06686563
- Testing
- Intervention Group: Gamma stimulation, Control Group: Theta stimulation
- Where
- Portugal
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Maria Paço
Dementia, Bipolar Disorder (BD)
Lithium for Prevention of Cognitive Declining in Mood Illnesses
INTRODUCTION: Mood disorders, bipolar disorder and recurrent unipolar depression, are among the most common mental health conditions worldwide.
- Conditions
- Dementia, Bipolar Disorder (BD), Depression - Major Depressive Disorder, Mild Cognitive Impairment (MCI)
- Trial name
- NCT06662526
- Testing
- Trace lithium dose plus treatment as usual
- Where
- 2 sites in Chile
- Volunteers
- 250 people
- Sponsor
- University of Chile
Anxiety, Anxiety Depression (Mild or Not Persistent)
The Effect of Patient-Family Communication Via Audio Recording
The study was conducted as a randomized controlled blinded study. The sample consisted of 55 patient relatives (27 in the experimental group and 28 in the control group).
- Conditions
- Anxiety, Anxiety Depression (Mild or Not Persistent), Satisfaction With Care
- Trial name
- NCT06627725
- Testing
- Patient-Family Communication
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Yasemin Kalkan Uğurlu
Depression in Old Age, Psychotherapy
Engage for Late-Life Depression and Comorbid Executive Dysfunction
Although there are an increasing number of mental health treatment adaptations for older adults, there are still a number of factors to consider when making these adaptations.
- Conditions
- Depression in Old Age, Psychotherapy, Mild Cognitive Impairment, Executive Dysfunction
- Trial name
- NCT05356611
- Testing
- Engage
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Nevada, Las Vegas
Depressive Episode, Depression
Sleep Signal Analysis for Current Major Depressive Episode (SAMDE)
The objective of this study is to collect data to finalize the development of MEB-001 software as a medical device. The data collected in this study will be used to develop MEB-001 machine learning algorithms by training the…
- Conditions
- Depressive Episode, Depression, Depressive Disorder, Depressive Disorder, Major
- Trial name
- SAMDE (NCT05708222)
- Testing
- MEB-001
- Where
- 13 sites in United States
- Volunteers
- 715 people
- Sponsor
- Medibio Limited
Depression, Post-COVID-19 Syndrome
Evaluation of DEPREXIL in Patients With Clinical Depression Through Psychological and Neuroendocrine Assessment
Clinical depression is a mood disorder that affects people of all ages with symptoms such as sadness, anger or frustration, appetite changes, difficulty concentrating and suicidal thoughts.
- Conditions
- Depression, Post-COVID-19 Syndrome, Depression Mild, Depression Moderate
- Trial name
- NCT06496087
- Testing
- DEPREXIL
- Where
- Colombia
- Volunteers
- 100 people
- Sponsor
- Catalysis SL
Depressive Symptoms, Mild Traumatic Brain Injury
Digital Therapeutic for Depression After Head Injury in Current and Former US Military Personnel
The Center for Neuroscience and Regenerative Medicine (CNRM) Clinical Trials Unit has developed the first cognitive-behavioral therapy (CBT) digital therapeutic (DTx) mobile application to counteract depressive symptoms in…
- Trial name
- NCT05147506
- Testing
- CNRM DTx, Psychoeducation Comparison
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Depression Moderate, Depression Mild
A Pilot Study Comparing the Efficacy of Traditional Buddhist Mindfulness Training Versus Secular Mindfulness-based Cognitive Therapy for Patients Having Residual Depressive Symptoms
This interventional study is conducted with the goal of comparing the efficacy of traditional Buddhist mindfulness training versus secular mindfulness based cognitive therapy among patients with depressive disorders.
- Trial name
- NCT06456931
- Testing
- Traditional Buddhist mindfulness, secular mindfulness based cognitive therapy
- Where
- Sri Lanka
- Volunteers
- 60 people
- Sponsor
- Anuradha Baminiwatta
Depression Mild, Depression Moderate
Integrated Depression Care
The Integrated DEpression CAre (IDECA) Programme is a multi-faceted intervention strategy aiming to improve guideline adherence and shared care practices for depression management in both providers and patients, as measured…
- Conditions
- Depression Mild, Depression Moderate, Depression Severe
- Trial name
- IDECA (NCT05788198)
- Testing
- Integrated care
- Where
- 2 sites in Belgium
- Volunteers
- 150 people
- Sponsor
- University Ghent
Mild-to-moderate Depression
Treating Depression With Transcutaneous Electrical Cranial-auricular Acupoint Stimulation (TECAS).
One multi-center, randomized controlled clinical trial is designed to examine whether transcutaneous electrical cranial-auricular acupoint stimulation (TECAS) is non-inferior to the antidepressant drug (Escitalopram) in treating…
- Trial name
- TECAS (NCT03909217)
- Testing
- TECAS Procedure, Escitalopram, Insomnia medication
- Where
- 6 sites in China
- Volunteers
- 470 people
- Sponsor
- The University of Hong Kong
Dementia, Mild, Mild Cognitive Impairment
CAPABLE Family Pilot - Adapting CAPABLE for Older Adults With Mild Cognitive Impairment (MCI)/Early Stage Dementia and Their Care Partners
The purpose of this study is to test the adapted protocol, CAPABLE Family which builds upon the evidenced based CAPABLE program to address older adults with co-occurring physical disability and mild cognitive impairment or early…
- Conditions
- Dementia, Mild, Mild Cognitive Impairment, Disability Physical, Impairment, Cognitive
- Trial name
- NCT05187117
- Testing
- CAPABLE Family - Open Label Pilot, CAPABLE Family - Randomized Control Trial
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Depression, Mild Cognitive Impairment
The Rapid Diagnosis of MCI and Depression in Patients Ages 60 and Over
Mild cognitive impairment (MCI) leading to Alzheimer's disease and related disorders (ADRD) represents a significant health and economic burden of the rapidly expanding senior population.
- Trial name
- NCT06011681
- Where
- 2 sites in United States
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- Miro Health
Low Mood, Mild Depression
Feasibility Study of an Online Physical Activity Intervention for Youth With Depression
Physical activity (PA) has recently been established as both a primary intervention for mild to moderate, and a secondary therapy for moderate to severe Major Depressive Disorder (MDD; Fortier et al., 2020).
- Conditions
- Low Mood, Mild Depression, Moderate Depression, Inactivity, Physical
- Trial name
- NCT05386745
- Testing
- physical activity
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Victoria
Mild to Moderate Depressive Symptoms
Effectiveness of Online Group-based Nonviolent Communication Interventions
This is a randomized controlled trial (RCT) to test the effectiveness of nonviolent communication (NVC) intervention for reducing parenting stress to parents with children in primary schools and mild to moderate depression.
- Trial name
- NCT05371002
- Testing
- Online group nonviolent communication (NVC) interventions, Waitlist control group
- Where
- China
- Volunteers
- 250 people
- Sponsor
- The University of Hong Kong
Exercise, Gait
Rhythmically Entrained Exercise in Community-Dwelling Older Adults
Researchers at the University of North Carolina at Greensboro conduct a single-arm intervention trial to investigate the efficacy of a music-based group exercise program for community-dwelling older adults.
- Conditions
- Exercise, Gait, Cognitive Decline, Caregiver Burden
- Trial name
- REECO (NCT05462977)
- Testing
- Group exercise program
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Greensboro
Specific Learning Disorder, Intellectual Disability, Mild to Moderate
SWELE Program: An Unstructured Outdoor Play With Mindfulness-based Interventions to Promote Mental Health Among Students With Special Education Needs
This is an observational study with the aim of SWELE Programme is to raise mental health knowledge and awareness by implementing a play-based approach on Supporting Wellness in E-Child Learning Environments (SWELE) programme…
- Conditions
- Specific Learning Disorder, Intellectual Disability, Mild to Moderate, Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
- Trial name
- SEN (NCT06112483)
- Testing
- SWELE Programme
- Volunteers
- 1,064 people
- Sponsor
- Chinese University of Hong Kong
Depression Mild, Depression Moderate
Long-term Effects ReSet Your Mind - Mechanisms
See: ClinicalTrials.gov ID: NCT05402150 Relevant for this Paper: This investigation aims to evaluate the stability of the effectiveness of different two-week online interventions in a four months follow-up regarding reward…
- Trial name
- NCT06072209
- Testing
- Behavioral Activation, Mindfulness and Gratitude, Combination of Behavioral Activation and Mindfulness and Gratitude
- Where
- Germany
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Philipps University Marburg
Depression Mild, Depression Moderate
An Online Intervention Targeting Depression and Low Reward Sensitivity
This study aims to evaluate and compare the effectiveness of different online interventions targeting reward sensitivity and depressive symptoms.
- Trial name
- NCT05402150
- Testing
- Behavioral Activation, Mindulness and Gratitude, Combination of Behavioral Activation and Mindfulness and Gratitude
- Where
- Germany
- Volunteers
- 224 people
- Sponsor
- Philipps University Marburg
Depression Mild, Cardiovascular Diseases
The Effect of Probiotics on Depression Syndrome and Risk Factors of Cardiovascular Disease in Hemodialysis Patients
As the investigators know, only few researches focus on the effect of probiotics on depression in hemodialysis patients. Besides, probiotics also have benefit effect on dyslipidemia and hypertension in general population.
- Trial name
- NCT05724511
- Testing
- MIYAIRI 588
- Where
- Taiwan
- Volunteers
- 55 people
- Sponsor
- China Medical University Hospital
Depressive; Episode, Major, Recurrent Depressive Disorder, Current Episode Moderate
Efficacy of Edupression.Com® in Depressive Patients
The aim of the study is to investigate the efficacy and adherence of the digital self-help programme edupression.com®.
- Conditions
- Depressive; Episode, Major, Recurrent Depressive Disorder, Current Episode Moderate, Recurrent Depressive Disorder, Current Episode Mild
- Trial name
- eFICASY (NCT04839822)
- Testing
- edupression.com®, Health tips, Surveys
- Where
- Austria
- Volunteers
- 250 people
- Sponsor
- Medical University of Vienna