Clinical trials: Depression Mild
Mental Health, Depression and/or Anxiety in the Mild-to-moderate Range
Effect of a Programme Including an AI-enhanced Mobile Application on the Mental Well- Being of Young Adolescents in Hong Kong
Study Aim and Methods (≈250 words) It aims to evaluate the effectiveness, user perceptions, and applicability of the e-CAMP intervention in improving mental well-being and reducing depressive symptoms among adolescents aged 11-15…
- Trial name
- AI-eCAMP_RCT (NCT07704996)
- Testing
- Control Group :health talk and usual care by school, mobile app group
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Tung Wah College
Depression and/or Anxiety in the Mild-to-moderate Range, Stress (Psychology)
SanaMente: A Peer-Led Program to Reduce Health Disparities in Rural Latino/a Communities
The goal of this clinical trial is to evaluate the feasibility, acceptability, and preliminary effectiveness of the SanaMente peer-led mental health and lifestyle program for rural Latino/a adults with chronic medical conditions…
- Conditions
- Depression and/or Anxiety in the Mild-to-moderate Range, Stress (Psychology), Chronic Medical Illness
- Trial name
- SanaMente (NCT07705776)
- Testing
- SanaMente
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Traumatic Brain Injury, Insomnia
CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms
This study is a prospective two-arm, single blind randomized controlled trial design to compare the clinical effectiveness of telemedicine-delivered, 6-session, standardized cognitive behavioral therapy for insomnia (CBT-I) and…
- Conditions
- Traumatic Brain Injury, Insomnia, Depression, Post-traumatic Stress
- Trial name
- NCT05663034
- Testing
- Mindfulness-based treatment for insomnia (MBTI), Cognitive behavioral therapy for insomnia (CBT-I)
- Where
- 5 sites in United States
- Volunteers
- 360 people
- Sponsor
- Johns Hopkins University
Depression Mild, Depression
fMRI Neurofeedback With Matter Neuroscience App
Study will utilize an app, Matter Neuroscience, designed to help users with depression understand positive emotions and the neurotransmitters that create them.
- Conditions
- Depression Mild, Depression, Depression Moderate
- Trial name
- NCT06735885
- Testing
- Matter Neuroscience App, Stock Photos, No Home Training
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Stanford University
Anxiety Depression (Mild or Not Persistent)
Implementation and Evaluation of an Internet-Based Stress Management Program for Health Students in the Sfax Region
The objective of this experimental study (randomized controlled trial) is to evaluate the effectiveness of an internet-based stress management program, inspired by the French program "Je gère mon stress," among healthcare…
- Trial name
- NCT07123311
- Testing
- Online Stress Management Program
- Where
- Tunisia
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- University of Sfax
Mild-to-moderate Depression, Neural Activity
Probiotics for Depressive Symptomatology and Neural Activity.
This study aims to investigate the acute and chronic effects of 16-week probiotic supplementation (Ecologic® Barrier) on depressive symptoms and neural activity in those with mild-to-moderate depression.
- Conditions
- Mild-to-moderate Depression, Neural Activity, Executive Function (Cognition)
- Trial name
- PRODAN (NCT07667530)
- Testing
- Ecologic® Barrier
- Where
- United Kingdom
- Volunteers
- 76 people
- Sponsor
- University of Reading
Concussion (Diagnosis), Concussion, Mild Traumatic Brain Injury
Multidimensional Sleep Health Intervention to Optimize Concussion Recovery
Following adolescent concussion, poor sleep health is common and relates to the development of persisting post-concussion symptoms, and uninjured adolescents (independent of concussion) also commonly experience sleep…
- Conditions
- Concussion (Diagnosis), Concussion, Mild Traumatic Brain Injury, Treatment, Sleep Health
- Trial name
- SCORE (NCT07082218)
- Testing
- Sleep Intervention
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Colorado, Denver
Mild Cognitive Impairment (MCI), Depressive Symptoms
rTMS Combined With Aerobic Exercise for Older Adults With Mild Cognitive Impairment and Comorbid Depression
This study aims to evaluate the effects of repetitive transcranial magnetic stimulation (rTMS) and aerobic exercise on cognitive function and mental health in older adults with mild cognitive impairment (MCI) and comorbid…
- Trial name
- NCT07652775
- Testing
- Repetitive Transcranial Magnetic Stimulation, Aerobic Exercise
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- Cheng-Hsin General Hospital
Depression, Mild or Moderate
Green VR for Depression
Depression is a common mental health condition that can cause low mood, lack of energy, sleep problems, and difficulties in daily functioning.
- Trial name
- VR&depression (NCT07530952)
- Testing
- Studio-based VR experiences, Self-managed VR experiences, Standard Treatment
- Where
- Norway
- Volunteers
- 45 people
- Sponsor
- Sykehuset Innlandet HF
Depression, Mild Traumatic Brain Injury
Combined Neuromodulation and Cognitive Training for Post-mTBI Depression
The primary goal of this clinical trial is to evaluate whether Personalized Augmented Cognitive Training (PACT) plus intermittent theta burst stimulation (iTBS) is effective for treating depression in Service Members, Veterans…
- Conditions
- Depression, Mild Traumatic Brain Injury, Concussion, Brain
- Trial name
- NCT05682677
- Testing
- iTBS, Personalized, Augmented Cognitive Training (PACT)
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of California, San Diego
Depression Mild, Depressive Disorder, Major
Cognitive Fitness for Depression in Older Adults
This research is being done to determine if computerized administered cognitive fitness activities will improve thinking and depression in older depressed adults who are being treated with antidepressants.
- Conditions
- Depression Mild, Depressive Disorder, Major, Mild Cognitive Impairment
- Trial name
- NCT04790630
- Testing
- Computerized Cognitive Remediation of Executive Functioning (CCR-EF), Active Control
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- UConn Health
Depressive Symptoms, Mild Traumatic Brain Injury
rTMS for Military TBI-related Depression
The purpose of this study is to investigate the efficacy, safety, and tolerability of two dorsolateral prefrontal cortex (DLPFC) repetitive transcranial magnetic stimulation (rTMS) protocols to alleviate symptoms of depression in…
- Conditions
- Depressive Symptoms, Mild Traumatic Brain Injury, Concussion
- Trial name
- ADEPT (NCT05426967)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- 3 sites in United States
- Volunteers
- 198 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Dementia, Mild, Depression
Decision Making Tool for Firearm Storage
This is a one-arm pilot study testing the feasibility and acceptability of a decision aid about safe firearm storage.
- Trial name
- NCT06382194
- Testing
- Decision aid
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Washington
Depressive Symptoms Mild to Moderate in Severity
Therapeutic Touch and Acupressure on Depressive Symptoms
Therapeutic touch intervention Participants in the therapeutic touch group received eight sessions over four weeks (two sessions per week), with each session lasting approximately 20 minutes.
- Trial name
- Postmenopausal (NCT07532512)
- Testing
- Therapeutic touch intervention, Acupressure intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Osmaniye Korkut Ata University
Mild Cognitive Impairment, Depression
Transcranial Magnetic Stimulation for MCI
The goal of this phase II study is to establish the dose-response curves of a safe and clinically feasible non-invasive brain stimulation technique (accelerated Transcranial Magnetic Stimulation (TMS)) to improve both depression…
- Trial name
- PUSH2 (NCT05992831)
- Testing
- Accelerated iTBS
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Medical University of South Carolina
Mild Cognitive Impairment (MCI), Subjective Cognitive Decrease (SCD)
A Graphene Far-infrared Intervention Study of Cognitive Status in Older Adults
This study is a 4-week group controlled trial to explore whether graphene far-infrared intervention can improve the cognitive status of older adults presenting with symptoms of Subjective Cognitive Decline (SCD), Mild Cognitive…
- Conditions
- Mild Cognitive Impairment (MCI), Subjective Cognitive Decrease (SCD), Alzheimer's Disease(AD), Depression/Anxiety Symptoms
- Trial name
- NCT06843824
- Testing
- a custom-made graphene therapy cap, A regular cap that generates heat
- Where
- China
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Institute of Psychology, Chinese Academy of Sciences
Mild Cognitive Impairment (MCI), Dementia Alzheimer Type
Global Collaborative Research on Establishing a Korean Cognitive Aging Cohort
The goal of this observational study is to learn how daily emotional stress affects cognitive function and inflammation in community-dwelling older adults aged 60 and older in Seoul, Republic of Korea.
- Conditions
- Mild Cognitive Impairment (MCI), Dementia Alzheimer Type, Chronic Pain, Depression - Major Depressive Disorder
- Trial name
- KoCoA cohort (NCT07485387)
- Where
- South Korea
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Korea University
Mental Health Issue, Anxiety Disorders
Arts-based Social Prescribing for Mental Health
This is a parallel-group randomised-controlled trial aiming to assess the effect of exposure to the arts on mental health and wellbeing of community dwelling recipients of mental health care.
- Conditions
- Mental Health Issue, Anxiety Disorders, Affective Disorders, Affective Disorders, Psychotic
- Trial name
- AoP-II (NCT07137572)
- Testing
- Art Prescription
- Where
- Greece
- Volunteers
- 541 people
- Sponsor
- KAVADIA ELENI
Mild Depression
Prefrontal Glutamatergic Modulation by NAC and MBCT for Depression in Youth
The primary goal is to investigate to what extent changes in glutamate and glutathione modulation and functional integration between brain networks associated with emotion and attention regulation are associated with treatment…
- Trial name
- NAC+MIND (NCT07464886)
- Testing
- N-acetylcysteine, Mindfulness-based cognitive therapy
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- University of Cincinnati
Neurocognitive Disorders, Mild, Cognitive Impairment, Mild
Effects of Personalized Digital Reminiscence Therapy on Patients With Neurocognitive Disorders
This study aims to observe the effects of daily personalized digital reminiscence sessions, conducted with the help of a digital conversational agent, and to determine whether these sessions lead to improvements in symptoms such…
- Conditions
- Neurocognitive Disorders, Mild, Cognitive Impairment, Mild, Depression Mild, Apathy
- Trial name
- NCT07237009
- Where
- 5 sites in France
- Volunteers
- 80 people
- Sponsor
- KompanionCare SAS