Clinical trials: Depression During Pregnancy
Pregnancy Related, Mental Health Issue
MamaConecta: Digital Tool for Maternal Mental Health
The goal of this randomized controlled trial is to validate a digital health tool, Dana app, that enhances well-being and supports mental health monitoring for women during the perinatal period.
- Conditions
- Pregnancy Related, Mental Health Issue, Postpartum Depression, Postpartum Anxiety
- Trial name
- DDT (NCT06442774)
- Testing
- Mobile application, Monitoring via wearable
- Where
- 3 sites in Spain
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- A Thousand Colibris, S.L
Insomnia in Pregnancy
Efficacy of Digital CBT-I Intervention During Pregnancy
This randomized controlled trial aims to evaluate the efficacy of Cognitive Behavioral Therapy for Insomnia in pregnant women. Particularly, this study aim to explore the effect of this intervention in ameliorating insomnia…
- Trial name
- NCT04350333
- Testing
- CBT-I, Assertive communication training
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of Rome G. Marconi
Postnatal Depression
Impact of Giving Birth During the Covid 19 Pandemia on Postnatal Women's Depression
Postnatal depression is an important problematic in French population with approximatively 10 -20% of women who suffer from postnatal depression. This pathology may have strong negative impact on both women and neonate's health.
- Trial name
- DEPRECOVID (NCT04368208)
- Testing
- Assessment of postnatal depression using the the Edinburgh questionnaire between 4 and 6 weeks after delivery
- Where
- France
- Volunteers
- 501 people
- Sponsor
- Poitiers University Hospital
High-risk Pregnancy, Hospitalization
LLM-Generated Medical Summaries During Hospitalization to Improve Patient Activation in High-Risk Pregnancies
The goal of this clinical trial is to learn if AI-generated medical summaries help hospitalized pregnant participants better understand and actively participate in their own care.
- Conditions
- High-risk Pregnancy, Hospitalization, Patient Activation, Artificial Intelligence (AI)
- Trial name
- NCT07823517
- Testing
- LLM-Generated Medical Summaries
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Sheba Medical Center
Premature Birth, Sedation During Labor and Delivery; Complications, Pulmonary
Magnesium for Neonatal Neuroprotection and Mothers
Magnesium is a treatment for mothers to protect brains of babies born early. This study investigates combined effects of magnesium and spinal or epidural anesthesia on mothers having cesareans.
- Conditions
- Premature Birth, Sedation During Labor and Delivery; Complications, Pulmonary, Respiratory Depression
- Trial name
- MnMs (NCT01482078)
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of British Columbia
Depressive Disorder
Omega-3 Fatty Acids for Major Depressive Disorder During Pregnancy
Whether high-dose omega-3 fatty acids supplement would be an effective treatment in patients with major depressive disorder during pregnancy and breast-feeding.
- Trial name
- NCT00618865
- Testing
- Omega-3 fatty acids
- Volunteers
- 36 people
- Sponsor
- National Science and Technology Council, Taiwan
Depression During Pregnancy
The Association Between Gut Microbiota Diversity and Postpartum Depression
This study aims to examine whether naturally occurring bacteria in the gastrointestinal tract are associated with mood changes following childbirth, including postpartum depression.
- Trial name
- NCT07227753
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Newborn Infant, Bonding
The Effect of Lullaby During Bath Time on Mother-Infant Bonding, Postpartum Depression, and Parental Self-Efficacy in Infants
This randomized, single-blind controlled trial aims to evaluate the effects of maternal lullaby singing during infant bathing on mother-infant bonding, postpartum depressive symptoms, and perceived parenting self-efficacy in…
- Conditions
- Newborn Infant, Bonding, Self Efficacy, Postpartum Depression (PPD)
- Trial name
- NCT07370025
- Testing
- Maternal Lullaby Singing
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Postoperative Pain, Postpartum Depression
Dose Low Dose Ketamine in Casesarian
The results of ketamine, ketamine and midazolom can be copied after birth in cesareans subjected to spinal anesthesia.
- Trial name
- ketamine (NCT06237569)
- Testing
- Application of ketamine and midazolam or ketamine alone to patients undergoing cesarean section under spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Inonu University
Pregnancy Related, Depression
Art Therapy in Obstetric Patients
This is a prospective study examining the potential impact art therapy has on postpartum depression and mother-baby bonding in women. Women who receive care at Washington Hospital Center's will be recruited for this study.
- Trial name
- NCT05503056
- Testing
- art therapy, nothing
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Depression, Anxiety Disorders
Effects of Interpersonal Psychotherapy on Depression During and After Pregnancy
This study will evaluate the impact of interpersonal psychotherapy on the course of depression during and after pregnancy, as well as its effect on infant birth outcomes.
- Trial name
- NCT00380419
- Testing
- Interpersonal Psychotherapy (IPT)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Michigan
Depression During Pregnancy, Postpartum Depression (PPD)
Treatment With Repetitive Transcranial Magnetic Stimulation in Peripartal Depression
The goal of this clinical trial is to learn whether repetitive transcranial magnetic stimulation (rTMS) can reduce depressive symptoms in women who are pregnant or up to 12 months after childbirth and have peripartum depression.
- Conditions
- Depression During Pregnancy, Postpartum Depression (PPD), Peripartum Depression
- Trial name
- PPD and rTMS (NCT07774559)
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- 2 sites in Switzerland
- Volunteers
- 60 people
- Sponsor
- Psychiatric University Hospital, Zurich
Depression, Pregnancy Related
Preventing Depressive Relapse in Pregnant Women With Recurrent Depression
The purpose of this investigation is to conduct a pragmatic effectiveness trial comparing digital mindfulness-based cognitive therapy (MBCT) plus usual care to usual care (UC) only among euthymic pregnant women with recurrent…
- Conditions
- Depression, Pregnancy Related, Antenatal Depression
- Trial name
- NCT03623620
- Testing
- Digital Delivery of Mindfulness-Based Cognitive Therapy
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- Massachusetts General Hospital
Postpartum Depression
Birth Experience During COVID-19 Confinement
Different studies have demonstrated that the absence of companionship during labor and childbirth may be responsible for a negative birth experience, an increased risk of postnatal depression and/or post traumatic stress…
- Trial name
- CONFINE (NCT04348929)
- Testing
- Self-administered questionnaires
- Where
- France
- Volunteers
- 927 people
- Sponsor
- Central Hospital, Nancy, France
Substance-Related Disorders, Pregnancy, High Risk
A Prenatal Mentalization-focused 4D Ultrasound and a Pregnancy Diary Intervention for Substance-abusing Women
Objective: This randomized and controlled trial was aimed at exploring the effect of a new mentalization-focused 4D interactive ultrasound and a week-by-week pregnancy diary intervention with substance-abusing pregnant women.
- Conditions
- Substance-Related Disorders, Pregnancy, High Risk, Prenatal Care, Maternal-Fetal Relations
- Trial name
- NCT03413631
- Testing
- Prenatal mentalization intervention, Prenatal obstetric treatment as usual
- Where
- Finland
- Volunteers
- 126 people
- Sponsor
- Turku University Hospital
Sexuality, Depression
Sexual Health Education During Pregnancy
This experimental, randomized controlled, single-blind study includes intervention and control groups. Pregnant women between 16 and 20 weeks of gestation who meet the inclusion criteria and agree to participate will be included…
- Conditions
- Sexuality, Depression, Pregnancy Related
- Trial name
- NCT07517549
- Testing
- sexuality health education group
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ordu University
Pregnancy, Primiparous Women
Maternal Reflective Functioning During the Transition to Motherhood
The goal of this clinical trial is to learn about Maternal Reflective Function (MRF) during the transition to motherhood. The main questions it aims to answer are: Does MRF mediates the connection between risk factors for mental…
- Trial name
- NCT06476626
- Testing
- Maternal Reflective Function Workshop
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Covid19
Anxiety and Depression Among Pregnant Women During COVID-19 Pandemic
Pregnancy and early parenthood are life changing periods characterized by intense emotions and a high vulnerability to emotional problems.
- Trial name
- NCT04558749
- Testing
- State-trait anxiety inventory scale, Edinburgh Postnatal Depression Scale (EDPS)
- Where
- Egypt
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Assiut University
Maternal Psychological Distress, Postpartum Depression
Mindfulness Based Cognitive Therapy (MBCT) During Pregnancy
The study is a pilot randomized control trial of a validated intervention, Mindfulness Based Cognitive Therapy (MBCT) adapted for pregnancy, developed to reduce risk for postpartum depression.
- Conditions
- Maternal Psychological Distress, Postpartum Depression, Prenatal Stress
- Trial name
- NCT03809572
- Testing
- Mindfulness Based Cognitive Therapy
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Pregnancy
Nutritional Status and Mental Health During Pregnancy and Postpartum: a Cohort Study in Rio de Janeiro, Brazil
There is increasing evidence that psychosocial factors may affect health by means of biological effects and changes in behavioral health.
- Trial name
- NCT01660165
- Where
- Brazil
- Volunteers
- 299 people
- Sponsor
- Universidade Federal do Rio de Janeiro