Clinical trials: Depression Disorders, open to volunteers
Depressive Disorder, Major Depressive Disorder
Ketogenic Diet for Depression
Globally, it's estimated that around 300 million people are affected by depressive illness, and even with access to modern mental health care, long-term recovery is uncommon.
- Conditions
- Depressive Disorder, Major Depressive Disorder, Depression, Bipolar
- Trial name
- KETO-MOOD (NCT06105762)
- Testing
- Ketogenic Diet
- Volunteers
- 120 people
- Sponsor
- University Psychiatric Clinics Basel
Kidney Transplant; Complications, Frailty Syndrome
Comprehensive Geriatric Assessment in Kidney Transplantation
This observational study aims to analyze the results of comprehensive geriatric assessment and to monitor the development of functional status in geriatric kidney transplant candidates and recipients.
- Conditions
- Kidney Transplant; Complications, Frailty Syndrome, Depressive Syndrome
- Trial name
- CoGeriaTx (NCT06104696)
- Testing
- Functional geriatric assessment
- Where
- Czechia
- Volunteers
- 1,000 people
- Sponsor
- Institute for Clinical and Experimental Medicine
Treatment Resistant Depression
Studying Patterns in Patient Engagement Among Treatment Resistant Depression Patients
Clinical studies, with a distinct focus on treatment resistant depression, play a crucial role in evaluating the safety and effectiveness of novel treatments.
- Trial name
- NCT06101914
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Power Life Sciences Inc.
Depression, Anxiety
Peripartum Mental Health Cohort Study in Guangzhou
The purpose of this study is to determine the incidence,development trajectory and risk factors of the main peripartum mental health problems as well as explore its adverse outcomes.
- Trial name
- NCT04499066
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Alcohol Use Disorder, Severe
Impact of Omega 3 in Alcohol Use Disorder
The goal of this clinical trial is to investigate the biological pathways underlying the beneficial effect of omega-3 polyunsaturated fatty acids (n-3 PUFA) on mental health in patients with alcohol use disorder.
- Trial name
- W3-AUD (NCT05899660)
- Testing
- Active Comparator: Omega-3
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Université Catholique de Louvain
Miscarriage
Interest of a Short Early Psychological Care in Women With Miscarriage
Miscarriage is a very common complication of pregnancy, accounting for 15.3% (95% CI 12.5-18.7%) of diagnosed pregnancies. Miscarriage would affect one in ten women during her lifetime.
- Trial name
- MisTher (NCT05653414)
- Testing
- short early psychological care associated with encouragement of early support consultation with generalist practitioner or midwife, encouragement of early support consultation with generalist practitioner or midwife
- Volunteers
- 932 people, healthy volunteers welcome
- Sponsor
- Université de Reims Champagne-Ardenne
Depression, Anxiety
Effect of Music Therapy in Mental Subhealth (EMTMS)
Mental health is increasingly at the forefront of concerns, especially since the start of COVID-19 pandemic. However, not all individuals under mental subhealth need pharmaceutical treatment.
- Trial name
- NCT05648539
- Testing
- The mini apps named "SOUL GYM" on the Wechat
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Jiangsu Province Nanjing Brain Hospital
Burnout, Stress
Effectiveness of Interventions to Improve Resiliency & Burnout in Behavioral Health Residential Staff
The goal of this clinical trial is to compare Integrated Resiliency Training and Task Sharing (IRTTS) to Workplace Improvement Learning Collaborative (WILC) in group homes for adults with serious mental illness and/or…
- Conditions
- Burnout, Stress, Coping Skills, Depression
- Trial name
- NCT05806112
- Testing
- Resiliency Training, Task Sharing, Workplace Improvement Learning Collaborative
- Where
- United States
- Volunteers
- 900 people
- Sponsor
- Massachusetts General Hospital
Conduct Problems, Anxiety Symptoms
Testing the Effectiveness of Supportive Parents - Coping Kids
The aim of this clinical trial is to test the effectiveness of the parent training intervention Supportive Parents - Coping Kids (SPARCK) for prevention of childhood mental health problems.
- Conditions
- Conduct Problems, Anxiety Symptoms, Depressive Symptoms
- Trial name
- SPARCK (NCT05800522)
- Testing
- Behavioral parent or child directed intervention, Supportive Parents - Coping Kids
- Where
- Norway
- Volunteers
- 252 people
- Sponsor
- Norwegian Center for Child Behavioral Development
Treatment Resistant Depression
Translational Biomarkers in Accelerated Neuromodulation for Treatment-resistant Depression
Background: 30-50% of patients with Major Depressive Disorder (MDD) do not respond adequately despite two or more antidepressant treatments with proper dosage and timing of administration, configuring a condition of…
- Trial name
- ReModula (NCT05798143)
- Testing
- Accelerated Repetitive Transcranial Magnetic Stimulation
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- ITAB - Institute for Advanced Biomedical Technologies
Inflammatory Bowel Diseases, Ulcerative Colitis
Gut Microbiome in Inflammatory Bowel Disease
Inflammatory bowel disease (IBD) is a chronic inflammatory condition for gastrointestinal tract. There have been numerous studies to reveal dysbiosis of fecal/mucosal microbiome composition in IBD patients but actual trend of…
- Conditions
- Inflammatory Bowel Diseases, Ulcerative Colitis, Crohn Disease
- Trial name
- NCT03589183
- Where
- South Korea
- Volunteers
- 1,500 people
- Sponsor
- Kyunghee University Medical Center
Hyperthermia, Major Depressive Disorder
Peripheral Neuroimmune Mechanisms of Hyperthermia
The goal of this study is to examine how whole-body hyperthermia affects the thermoinflammatory profile, which includes the combined immune and heat shock response, in patients with depression and whether these changes correlate…
- Conditions
- Hyperthermia, Major Depressive Disorder, Inflammation
- Trial name
- NCT05366270
- Testing
- WBH
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Treatment-resistant Depression
The Mechanisms of Underlying Accelerated Repetitive Transcranial Magnetic Stimulation for Treatment-resistant Depression
In this project, the investigators evaluate an accelerated schedule of repetitive transcranial magnetic stimulation for treatment-resistant depression.
- Trial name
- NCT05607654
- Testing
- active iTBS
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Pregnancy, Postpartum
HIIT vs MICT During Pregnancy and Health and Birth Outcomes in Mothers and Children
Regular exercise during pregnancy and postpartum leads to health benefits for mother and child. Inactivity during pregnancy and after delivery is now treated as risky behavior.
- Conditions
- Pregnancy, Postpartum, Childbirth, Health Status
- Trial name
- HIIT MAMA (NCT05009433)
- Testing
- High intensity interval training program for pregnant women, Moderate intensity continuous training program for pregnant women, Standard obstetric care with extended education on healthy lifestyle
- Where
- Poland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Depressive Disorder, Depression
Prediction and Validation of Unipolar Depression With Psychosocial-somatic Markers in a Naturalistic Cohort Recruited in an Outpatient Setting
The POKAL-PSY project is a study that monitors participants for five years. The goal of the study is to identify distinguishable subtypes of depression on the basis of biomarkers and to gain insight into their prognostic…
- Conditions
- Depressive Disorder, Depression, Depressive Symptoms, Depressive Episode
- Trial name
- POKAL-PSY (NCT05547711)
- Testing
- drawing blood
- Where
- Germany
- Volunteers
- 950 people, healthy volunteers welcome
- Sponsor
- Julia Eder
Geriatric Disorder, Depression
Quality Register for Geriatric Psychiatry
QualGeP (KVALAP) is a quality register in Viken Research network for Geriatric Psychiatry. The objectives of the register are to enhance our knowledge of old persons with severe psychiatric disorders, and to secure an optimal…
- Trial name
- KVALAP (NCT01415310)
- Where
- Norway
- Volunteers
- 19,000 people
- Sponsor
- Geir Selbaek
Mental Disorder, Mental Stress
Virtual Agents-based Digital Interventions to Improve Health
KANOPEE is a free smartphone application providing screening, follow-up tools and autonomous digital interventions to lower psycho-social stress and its repercussions on sleep and behaviors in the general population.
- Conditions
- Mental Disorder, Mental Stress, Insomnia, Depression
- Trial name
- KANOPEE (NCT05074901)
- Testing
- digital behavioral intervention
- Where
- France
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- University of Bordeaux
Major Depressive Disorder, Postpartum Depression
Maternal Mental Health Trial
Perinatal depression affects 10-15% of women postpartum and has a recurrence rate of 40%. Women who develop perinatal depression might be particularly susceptible to the rapid and large changes in sex steroid hormones…
- Trial name
- MAMA (NCT04685148)
- Testing
- Transdermal patch estradiol
- Where
- Denmark
- Volunteers
- 220 people
- Sponsor
- Vibe G Frøkjær, MD, PhD
Depression, Cost Benefit Analysis
Dysthymia: Associated Costs, Treatment and Change Process
The study evaluates cost and effect of inpatient versus outpatient treatment of dysthymia, as well as investigates the processes through which psychotherapy works in treating dysthymia.
- Conditions
- Depression, Cost Benefit Analysis, Psychotherapeutic Processes
- Trial name
- DFront (NCT04911829)
- Testing
- Psychotherapy
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Modum Bad
Depression, Anxiety
Creatine for Depressed Male and Female Methamphetamine Users
Assess the antidepressant/anxiolytic effect of creatine in male and female methamphetamine users Assess creatine's effect on methamphetamine use Assess the safety of creatine in male methamphetamine users with depression
- Conditions
- Depression, Anxiety, Methamphetamine Dependence
- Trial name
- NCT02568878
- Testing
- Creatine monohydrate
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Montana State University