Clinical trials: Depression Disorders, open to volunteers
Major Depression
Interpersonal Psychotherapy for Adolescents and Young Adults
The purpose of the project is to study the effectiveness of Interpersonal Psychotherapy (IPT) for adolescents with depression. Specific aims are to analyze the effects, change mechanisms, predictors, and implementation of IPT for…
- Trial name
- NCT05575960
- Testing
- Interpersonal Psychotherapy for Adolescents (IPT-A)
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Linnaeus University
Depression, Major Depressive Disorder
Non-invasive BCI and Application Verification for Depressed People
Major Depressive Disorder (MDD) is a serious mental illness and public health problem that poses threat to both physical and mental health.
- Conditions
- Depression, Major Depressive Disorder, Bipolar Depression
- Trial name
- NCT06417437
- Testing
- SSRI, rTMS, Neuro-Feedback
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Schizophrenia, Schizoaffective Disorder
The Efficacy of Metacognitive Skills Training in the Context of Forensic Psychiatric Care
Deficiencies in social cognition are part of the core symptomatology of psychotic disorders. And deficiencies in social cognition, the closely related concept of metacognition, and, for example, paranoid attitudes are all…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Psychotic Disorders, Delusional Disorder
- Trial name
- NCT06005766
- Testing
- Metacognitive Skills Training (MCT), Treatment as usual
- Where
- Finland
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Jyvaskyla
Major Depressive Disorder
Psychopharmacotherapy for Depressive Patients
The primary purpose of this study is to compare the short (12 week) and long-term (1-year) efficacy and the tolerability between stepwise psychopharmacotherapy and antidepressant monotherapy for 12 weeks in adult patients with…
- Trial name
- BMDD-2022 (NCT06054321)
- Testing
- stepwise pharmacotherapy, antidepressant monotherapy group
- Where
- South Korea
- Volunteers
- 400 people
- Sponsor
- Chonnam National University Hospital
Obesity, Depressive Symptoms
The MIND-GUT Digital Pilot Intervention Study
This 12-week pilot study aims to evaluate the feasibility and effectiveness of a dietary intervention targeting diet, obesity, mental health, and the gut microbiome in promoting weight loss and enhancing mental health among obese…
- Conditions
- Obesity, Depressive Symptoms, Anxiety, Stress
- Trial name
- MINDGUT (NCT06374407)
- Testing
- Dietary intervention based on the MIND diet
- Where
- Sweden
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Skövde
Depression, Anxiety Disorders
An Exploratory Study Examining Biopsychosocial Markers of Anxiety and Depression
This research study is studying how thoughts, feelings, surroundings, and individual biology may contribute to why and how people experience anxiety or depression.
- Conditions
- Depression, Anxiety Disorders, Stress Related Disorder
- Trial name
- BPS (NCT05466851)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Singula Institute
Anxiety, Depressive Symptoms
Efficacy of Digital Problem Solving Application in Reduction of Anxiety, Depression and Substance Use Disorder Symptoms
The focus of this study is the impact of usage of a mobile application to support problem-solving therapy on symptoms of anxiety, depression and substance use.
- Conditions
- Anxiety, Depressive Symptoms, Substance Use Disorders
- Trial name
- Efficacy (NCT06346431)
- Testing
- DSPT - Digital Support for Problem-solving Therapy
- Volunteers
- 100 people
- Sponsor
- 7 Generation Games
Diary (Blank Journal), Intensive Care Unit
Efficacy of the Use of Diaries in Intensive Care Units
Randomized clinical trial that aims to evaluate the impact of the use of a diary in patients and relatives of patients admitted to an ICU in relation to usual practice in terms of health-related quality of life, the…
- Conditions
- Diary (Blank Journal), Intensive Care Unit, Patient, Family
- Trial name
- QUADERN (NCT05288140)
- Testing
- use of diary
- Where
- Spain
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Major Depressive Disorder
Stress Management in Depressive Disorder: Resilience Training vs. Yoga: Biological, Epigenetic, and Brain Correlates
The aim of this clinical trial is to evaluate the effects of a Resilience and Stress Management Intervention Program (RASMUS) compared with yoga on stress perception, coping strategies, depressive symptoms, anxiety, resilience…
- Trial name
- NCT06229652
- Testing
- RASMUS Resilience Training, Body-oriented Yoga
- Where
- Austria
- Volunteers
- 150 people
- Sponsor
- Medical University Innsbruck
Depression in Old Age, Chronic Pain
Development of a Healthcare Service Platform for Successful Aging
The goal of this living-lab clinical trial is to test the effectiveness of digital health monitoring and feedback platform for community dwelling older adults.
- Conditions
- Depression in Old Age, Chronic Pain, Sleep Disorder Insomnia Chronic
- Trial name
- NCT06270121
- Testing
- Living-lab digital intervention group
- Where
- South Korea
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Sunmi Song
Major Depression
Added Value of a Neuroendocrine Test Battery in the Response to Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment
The primary objective of the study is to determine the predictive value of the neuroendocrine tests TRH-∆∆TSH (thyreoliberin - thyreostimulin) and DST (dexamethasone suppression test) in the subsequent response to rTMS-TBS…
- Trial name
- Endo-rTMS (NCT05964192)
- Testing
- Repetitive transcranial magnetic stimulation (rTMS)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Rouffach
Aortic Stenosis, Anxiety
10-year Follow-up After Aortic Valve Replacement Surgery
There is a lack of data on patients self-reported outcomes (PROMs) on health-related quality of life (HRQoL)and symptoms on anxiety and depression 10 years after Surgical After Aortic Valve Replacement (SAVR), and patient…
- Conditions
- Aortic Stenosis, Anxiety, Depressive Symptoms, Quality of Life
- Trial name
- AVR-10year (NCT06255691)
- Volunteers
- 282 people
- Sponsor
- Oslo University Hospital
Depression, Anxiety, Trauma
Psychoeducation, Relaxation, PrOblem Solving, Activation, Cognitive Coping Therapy for Adolescents and Youth in HIV Care
The proposed PROACT study will test the effectiveness of a mental health intervention (psychotherapy) for multiple common mental health conditions (depressive, anxiety and trauma symptoms) among adolescents and youth with HIV in…
- Conditions
- Depression, Anxiety, Trauma, HIV-1-infection
- Trial name
- PROACT (NCT06247527)
- Testing
- Psychoeducation, Relaxation, PrOblem solving, Activation, Cognitive coping Therapy, Standard of care
- Where
- Kenya
- Volunteers
- 600 people
- Sponsor
- University of Nairobi
PTSD, Post Traumatic Stress Disorder, Major Depressive Disorder
Ketamine Treatment for PTSD and MDD in TBI
The goal of this clinical trial is to examine the use of sedative ketamine to treat depression and post-traumatic stress disorder (PTSD) in Veterans with mild to moderate traumatic brain injury (TBI).
- Conditions
- PTSD, Post Traumatic Stress Disorder, Major Depressive Disorder, Traumatic Brain Injury
- Trial name
- NCT06228391
- Testing
- IV ketamine, Midazolam
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Minneapolis Veterans Affairs Medical Center
Depression, Unipolar, Fall
Integrated Tele-Behavioral Activation and Fall Prevention for Low-income Homebound Seniors With Depression
This study will test clinical and cost effectiveness of an integrated tele- and bachelor's-level counselor/coach delivered behavioral activation (BA) and fall prevention (FP) for low-income homebound older adults.
- Trial name
- TBF (NCT05011864)
- Testing
- Behavioral Activation, Fall Prevention, Telephone support
- Where
- United States
- Volunteers
- 320 people
- Sponsor
- University of Texas at Austin
Autism, Autism Spectrum Disorder
The Supplementation Therapy in Autism and Response to Treatment Study
In addition to the "core" symptoms of ASD (i.e., impaired communication, impaired reciprocal social interaction and restricted, repetitive and stereotyped patterns of behaviors or interests), it is estimated that up to 70% of…
- Conditions
- Autism, Autism Spectrum Disorder, Autism Spectrum Disorder High-Functioning, Asperger Syndrome
- Trial name
- START (NCT06187090)
- Testing
- Oral Ultramicronized-Palmitoylethanolamide (um-PEA; 600 mg per day) in tablet form
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University of Udine
Major Depressive Disorder
Feasibility of Conducting a Clinical Trial Assessing Efficacy of Lactate as Adjunctive Therapy in Patients With Major Depressive Disorder
The goal of this clinical trial is to test the efficacy of lactate (a natural substance) in combination with standard antidepressant treatment, in patients hospitalized for a major depressive episode.
- Trial name
- NCT06168175
- Testing
- Sodium lactate
- Volunteers
- 46 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Depression, Anxiety
Effects of CBT-Based Intervention Among Patients With Liver Cancer
This study investigates the effects of a CBT- based intervention on depression, anxiety, immune function, quality of life, and overall survival.
- Conditions
- Depression, Anxiety, Liver Cancer, CBT
- Trial name
- NCT05942560
- Testing
- Cognitive behavioural therapy-based intervention, Educational group
- Where
- China
- Volunteers
- 160 people
- Sponsor
- The Nethersole School of Nursing
Malignant Tumor, Anxiety
Long-term Follow-up of Anxiety and Depression in Patients With Malignant Tumors
This study was a single-center prospective, real-world observational study with plans to enroll all eligible patients. The basic information, anxiety and depression, treatment and prognosis of these patients were collected.
- Conditions
- Malignant Tumor, Anxiety, Depression
- Trial name
- NCT05596344
- Testing
- Hospital Anxiety and Depression Scale
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Henan Cancer Hospital
Depression, Schizophrenia
Norwegian Adult Mental Health Registry
"The Norwegian Adult Mental Health Registry" (NAMHR) is a medical quality register collecting and systematizing data on patients and their treatment in specialist mental health care for adults in Norway.
- Conditions
- Depression, Schizophrenia, Bipolar Disorder, Eating Disorders
- Trial name
- NAMHR (NCT06115200)
- Volunteers
- 150,000 people
- Sponsor
- Helse Stavanger HF