Clinical trials: Depression Disorders, open to volunteers
Depression, Anxiety
Studying Impact of Religiosity and Spirituality on Depression and Anxiety
The aim of the study is to detect correlation between religiosity/spirituality and severity of depression and anxiety as well as finding impact on quality of life in patients, suffering from one of those disorders or both, who…
- Trial name
- NCT06642298
- Volunteers
- 52 people
- Sponsor
- Assiut University
Mindfulness, Self-Compassion
Focus Group Study on the Feeling Tone Mindfulness Course
This is an academic research study aiming to explore the acceptability, feasibility, and effectiveness of a four-week feeling tone mindfulness course by gathering qualitative feedback from course participants in a focus group…
- Conditions
- Mindfulness, Self-Compassion, Depression, Anxiety
- Trial name
- NCT06621108
- Testing
- Focus group session
- Where
- Hong Kong
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Thyroid Nodule
Health-Related Quality of Life and Emotions in Patients with Thyroid Nodules
The purpose of this observational research is to evaluate and compare the health-related quality of life and emotional well-being of patients with thyroid nodules before and after treatment.
- Trial name
- NCT06610604
- Testing
- thermal ablation, thyroidectomy
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Ming-an Yu
TBI (Traumatic Brain Injury), Depressive Disorder, Major
InMotion - Telehealth Delivered Exercise Promotion to Treat Major Depression After TBI
The purpose of this randomized controlled trial is to evaluate whether the InMotion intervention, delivered via telehealth (using a HIPAA-compliant video platform or phone), which uses evidence-based behavioral and motivational…
- Conditions
- TBI (Traumatic Brain Injury), Depressive Disorder, Major, Clinical Depression, Mood Depressed
- Trial name
- NCT06005194
- Testing
- InMotion
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Washington
Treatment Resistant Depression
Psilocybin for Hospitalized Patients with Treatment-resistant Depression
The purpose of this study is to determine the safety and feasibility of performing psilocybin-assisted psychotherapy in patients hospitalized for treatment-resistant depression.
- Trial name
- PSIHOS-D (NCT06378229)
- Testing
- Psilocybin
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent
Perinatal Depression, PerinatalAnxiety
Perinatal Depression & Anxiety (PDA) and Maternal Gut Microbiome
Perinatal depression and anxiety (PDA) are the leading causes of maternal mortality in developed countries. Women with a history of depression have a 20 fold higher risk of PDA at subsequent pregnancies.
- Trial name
- NCT06074250
- Testing
- Fish oil, Probiotics, Prebiotics
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- The Canadian College of Naturopathic Medicine
Herpes Zoster
Risk Factors of Anxiety and Depression in Patients With Herpes Zoster Neuralgia
The goal of this observational study is to explore risk factors of anxiety and depression in patients with herpes zoster neuralgia, and the changes of certain serum biomarkers and functional brain magnetic resonance images of…
- Trial name
- NCT06449547
- Testing
- Hospital Anxiety and Depression Scale
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Huazhong University of Science and Technology
Major Depressive Disorder
Effects of rTMS Compared to SSRI as Early Treatment of Depression (Early-TMS)
The aim of this randomized multicentre phase 2 clinical trial is to compare the effects of rTMS and SSRI medication as early treatment of depression.
- Trial name
- Early-TMS (NCT06545474)
- Testing
- bilateral theta burst stimulation, SSRI treatment
- Volunteers
- 106 people
- Sponsor
- University Hospital Tuebingen
Major Depressive Disorder, Suicidal Behavior
Basal Plasma Lithium Levels and Suicidal Events
Suicidal behavior is a major public health issue and there are currently no specific treatments for it. However, lithium, the reference treatment for bipolar disorder, have been shown to be effective in preventing suicidal risk.
- Conditions
- Major Depressive Disorder, Suicidal Behavior, Bipolar Disorder
- Trial name
- LIPS (NCT05409794)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 158 people
- Sponsor
- University Hospital, Montpellier
Major Depressive Disorder \(MDD, Depressive Disorder, Major
Electrical Vestibular Nerve Stimulation (VeNS) as a Treatment for Major Depressive Disorder (MDD)
Trial title: A Randomized, Double Blind Sham Controlled Clinical Trial to Evaluate the Efficacy of Electrical Vestibular Nerve Stimulation (VeNS), Compared to a Sham Control for Treatment of Major Depressive Disorder (MDD) …
- Trial name
- NCT06470035
- Testing
- Active VeNS Device
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 170 people
- Sponsor
- Neurovalens Ltd.
Major Depressive Disorder, Treatment Resistant Depression
Identifying Local Field Potential Biomarkers for Treatment-Resistant Major Depression With Deep Brain Stimulation
Major depressive disorder (MDD) is a complex and severe mental illness, characterized by multiple symptoms, and is a leading cause of non-fatal health loss.
- Trial name
- NCT06542094
- Testing
- Deep Brain stimulation
- Where
- China
- Volunteers
- 12 people
- Sponsor
- West China Hospital
Treatment Resistant Depression
Efficacy of Deep Brain Stimulation(DBS) for Treatment-Resistant Depression(TRD)
The primary purpose of this study is to investigate the effect of deep brain stimulation (DBS) implantation in patients with Treatment-resistant Depression (TRD) targeting the ventral capsule/ventral striatum (VC/VS), Brodmann…
- Trial name
- DBS for TRD (NCT06542900)
- Testing
- Deep Brain Stimulation (DBS)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xuanwu Hospital, Beijing
Depression, Unipolar, Depression Moderate
The Cerebral and Cognitive Changes After Intermittent Theta Burst Stimulation (iTBS) Treatment for Depression
The present project aims to assess the neurocognitive impact of a two-week once-a-day regimen of intermittent theta burst stimulation (iTBS) compared to sham iTBS, when targeting the left dorsolateral prefrontal cortex (LDLPFC)…
- Trial name
- NCT06534684
- Testing
- Intermittent Theta Burst Stimulation
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- University Hospital of North Norway
Psychosis, Mania
Combining mHealth and Nurse-delivered Care to Improve the Outcomes of People With Serious Mental Illness in West Africa
In West Africa, most people with serious mental illness receive care from traditional or faith healers at prayer camps. The stepped-wedge cluster randomized trial aims to evaluate the effectiveness of a dual-pronged intervention…
- Conditions
- Psychosis, Mania, Depression
- Trial name
- NCT05703711
- Testing
- mHealer
- Where
- Ghana
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Washington
Major Depressive Disorder, MDD
Operation of Brain Stimulation Equipment Under Remote Viewing Effectiveness Registry
The goal of this observational study is to record and analyze factors putatively affecting the clinical outcomes among patients undergoing transcranial magnetic stimulation (TMS) treatment for major depressive disorder (MDD) or…
- Conditions
- Major Depressive Disorder, MDD, Generalized Anxiety Disorder, GAD
- Trial name
- OBSERVER (NCT06512324)
- Testing
- Ampa One TMS System
- Where
- 2 sites in United States
- Volunteers
- 5,000 people
- Sponsor
- Biomedical Discoveries and Neuroscientific Foundations LLC
Depression, Anxiety
CES and EGChatbot in Reducing Anxiety, Depression, Insomnia, and Mental Risk
The objective of this three-year study is to provide comprehensive care to young adults presenting with ARMS. The aim is use an exercise group (EGChat) developed by prior study and CES to decrease cognitive mental risks, improve…
- Trial name
- NCT06493695
- Testing
- Both EGChat and CES intervention, Exercise Chatbot, CES (Cranial Electrotherapy Stimulation)
- Where
- Taiwan
- Volunteers
- 180 people
- Sponsor
- China Medical University Hospital
Pregnancy, Primiparous Women
Maternal Reflective Functioning During the Transition to Motherhood
The goal of this clinical trial is to learn about Maternal Reflective Function (MRF) during the transition to motherhood. The main questions it aims to answer are: Does MRF mediates the connection between risk factors for mental…
- Trial name
- NCT06476626
- Testing
- Maternal Reflective Function Workshop
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Mental Health Issue, Depression, Anxiety
A Study on Young Individuals' Mental Health in Sweden
The goal of this observational study is to increase our knowledge about the mental health of young individuals and to establish a valid and comprehensive method for assessing mental health in young individuals (15-29 years) that…
- Conditions
- Mental Health Issue, Depression, Anxiety, Well-Being, Psychological
- Trial name
- UPIC (NCT06490120)
- Testing
- sampling method
- Where
- Sweden
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Depression, Anxiety
Psychiatric Outreach Nurses Supporting Adolescent Mental Health
The study evaluates the effectiveness and cost-effectiveness of the outreach work of psychiatric registered nurses (RN) and the experiences of professionals in the field. The service is provided in school environment.
- Trial name
- JAPSY (NCT06438276)
- Testing
- Psychiatric outreach nurse service
- Where
- Finland
- Volunteers
- 160 people
- Sponsor
- University of Eastern Finland
Anxiety, PTSD
Evaluation of the H.O.O.V.E.S. Healing Intensives Program
The aim of this study is to measure the impact of these H.O.O.V.E.S. healing intensives on Veteran participants using several psychological instruments.
- Conditions
- Anxiety, PTSD, Depression
- Trial name
- NCT06300255
- Testing
- H.O.O.V.E.S. Healing Intensives
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- VA Salt Lake City Health Care System