Clinical trials: Depression Disorder
Anxiety, Depression
Compassion Training and Mindfulness Training for Social Well-Being and Mental Health
Study Design, Aims, and Population: The present study is a three-arm randomized controlled trial (RCT). The primary aim is to test the relative efficacy of two 8-week online interventions - Compassion Cultivation Training (CCT)…
- Conditions
- Anxiety, Depression, Stress, Burnout
- Trial name
- NCT05227794
- Testing
- Compassion Cultivation Training (CCT), Mindfulness-Based Stress Reduction (MBSR)
- Where
- United States
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Yale University
Depressive; Episode, Major, Recurrent Depressive Disorder, Current Episode Moderate
Efficacy of Edupression.Com® in Depressive Patients
The aim of the study is to investigate the efficacy and adherence of the digital self-help programme edupression.com®.
- Conditions
- Depressive; Episode, Major, Recurrent Depressive Disorder, Current Episode Moderate, Recurrent Depressive Disorder, Current Episode Mild
- Trial name
- eFICASY (NCT04839822)
- Testing
- edupression.com®, Health tips, Surveys
- Where
- Austria
- Volunteers
- 250 people
- Sponsor
- Medical University of Vienna
Post-traumatic Stress Disorder, Depression
Randomized Control Trial of Group Intervention With Former War-affected Boys in the Democratic Republic of Congo
The purpose of this study is to evaluate, in a randomised control trial (RCT), the effectiveness of group-based, trauma-focused Cognitive Behaviour Therapy (TF-CBT) in reducing psychological distress in former child soldiers and…
- Conditions
- Post-traumatic Stress Disorder, Depression, Conduct Disorder
- Trial name
- NCT01494831
- Testing
- TF-CBT
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Anxiety Disorders, Depression
Personalized Feedback for Distress Intolerant Smokers
This project will develop and refine a computer-delivered integrated Personalized Feedback Intervention (PFI) that directly addresses smoking and distress tolerance.
- Conditions
- Anxiety Disorders, Depression, Psychological Distress, Tobacco Dependence
- Trial name
- NCT03918031
- Testing
- PFI for Smoking & Distress Tolerance, PFI for Smoking Only
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- University of Houston
Sleep Quality
Effects of Binaural Beat Music on Elderly Sleep
Background: Older people in long-term care institutions often have poor sleep quality and depression, which may negatively affect their health and welfare. Binaural beat music (BBM) has been proposed as a possible intervention.
- Trial name
- NCT05975853
- Testing
- Binaural beat music group (BBM group), Control group
- Where
- Taiwan
- Volunteers
- 64 people
- Sponsor
- National Cheng Kung University
Major Depressive Disorder
Genetic Study of Liver Enzymes in Patients With Side Effects From Antidepressants
The objective of this pilot study is to determine the genetic polymorphism rate of CYP450 2D6 and 2C19 metabolic enzymes in patients with significant adverse effects from antidepressants, compared to a population of patients who…
- Trial name
- NCT00360256
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Augusta University
Suicidal Ideation, Major Depressive Disorder
Low Amplitude Pulse Seizure Therapy Versus Standard Ultra-Brief Right Unilateral Electroconvulsive Therapy
This protocol proposes an initial randomized clinical trial that includes all patients with suicidal ideation (SI) at baseline, and with SI as the primary outcome measure to examine whether Right Unilateral Low-Amplitude Pulse …
- Conditions
- Suicidal Ideation, Major Depressive Disorder, Schizo Affective Disorder, Bipolar Disorder
- Trial name
- LAP-ST vs ECT (NCT06529029)
- Testing
- Sigma-Stim, RUL LAP-ST (Low-Amplitude Pulse Seizure Therapy - Right Unilateral)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Michigan State University
PTSD, Alzheimer Disease
First-In-Human (FIH), Single Ascending Dose (SAD) Study of FluoroEthylNorMemantine (FENM)
The goal of this First-In-Human (FIH) trial is to learn about safety and PharmacoKinetics (PK) in healthy adult volunteers. The main questions it aims to answer are: What is the safety of single ascending doses of the…
- Conditions
- PTSD, Alzheimer Disease, Brain Diseases, Neuro-Degenerative Disease
- Trial name
- NCT05921929
- Testing
- Fluoroethylnormemantine (FENM)
- Where
- Belgium
- Volunteers
- healthy volunteers welcome
- Sponsor
- ReST Therapeutics
Cancer
Islamic Spiritual Care Versus Psychological Support in Radiotherapy
This study evaluated the effects of IHSAN Model-based Islamic spiritual care compared with cognitive behavioral therapy (CBT)-based psychological support and routine care in Muslim patients with cancer receiving radiotherapy.
- Trial name
- NCT07861451
- Testing
- IHSAN Model-based Islamic Spiritual Care, CBT-based Psychological Support
- Where
- Turkey (Türkiye)
- Volunteers
- 137 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Stress Disorders, Post-Traumatic, Depression
Veteran Health Study
The purpose of The Veteran Health Study (CSP #569) is to better understand the mental and physical health of veterans as they get older.
- Conditions
- Stress Disorders, Post-Traumatic, Depression, Diabetes, Cardiovascular Disease
- Trial name
- NCT01175629
- Where
- United States
- Volunteers
- 7,568 people
- Sponsor
- US Department of Veterans Affairs
Atrial Fibrillation
Effects of Mindfulness on Atrial Fibrillation
This study aims to investigate the effect of MUSE (R) Headbands on patients with Atrial Fibrillation who is awaiting pulmonary vein isolation ablation procedure. Patients are randomized in 2 arms.
- Trial name
- NCT02564302
- Testing
- MUSE Headband
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Newmarket Electrophysiology Research Group Inc
Intimate Partner Violence (IPV), Anxiety
Effectiveness of Community-based Approach in Reducing the Intimate Partner Violence (IPV) Exposure and Outcome
Abstract Background: There is a little known about the effectiveness of Community-Based Approach (CBA) on reduction of intimate partner violence (IPV) exposure, anxiety, depression and PTSD symptoms as outcomes in collectivist…
- Conditions
- Intimate Partner Violence (IPV), Anxiety, Depression, Post-traumatic Stress Disorder (PTSD)
- Trial name
- NCT06768502
- Testing
- Community Based Approach (CBA)
- Where
- Rwanda
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Rwanda
Depressive Disorder, Treatment-Resistant
Brain Connectivity and Inflammatory Markers During Short-Term Psychotherapy for Treatment-Resistant Depression
Some adults continue to experience depression despite treatment with antidepressant medicines. This study aimed to explore relationships between depression symptoms, brain function, and blood markers of inflammation, and changes…
- Trial name
- NCT07847242
- Testing
- Short-Term Dynamic Psychotherapy, Mindfulness-Based Cognitive Therapy
- Where
- South Korea
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Korea University Ansan Hospital
Sleep Disorders, Obstructive Sleep Apnea
Efficacy and Safety of Armodafinil for Adults With Excessive Sleepiness Obstructive Sleep Apnea/Hypopnea and Depression
The primary objective of the study is to evaluate whether armodafinil at a target dosage of 200 mg/day is more effective than placebo treatment in improving excessive sleepiness in patients with obstructive sleep apnea/hypopnea…
- Conditions
- Sleep Disorders, Obstructive Sleep Apnea, Major Depressive Disorder, Dysthymic Disorder
- Trial name
- NCT00518986
- Testing
- armodafinil
- Where
- 62 sites in United States
- Volunteers
- 249 people
- Sponsor
- Cephalon
Self Efficacy, Neoplasms (Cancer / Tumors)
Identifying and Mobilizing Personal Resources to Improve Well-Being in Cancer Participants Using the CAERES Protocol
Cancer patients often experience emotional distress, fatigue, and reduced quality of life that may not be fully addressed by medical treatment alone.
- Conditions
- Self Efficacy, Neoplasms (Cancer / Tumors), Cancer-related Fatigue, Post-Traumatic Growth, Psychological
- Trial name
- CAERES (NCT07582666)
- Testing
- CAERES (Cancer Auto-Evaluation of RESources) Psychosocial Intervention
- Where
- 3 sites in Switzerland
- Volunteers
- 32 people
- Sponsor
- UniDistance Suisse
Depressive Disorder, Major
A Study of Participants With Moderate or Severe Major Depressive Disorder (MDD) Requiring Urgent Symptom Control in a Psychiatric Emergency
The purpose of the study is to describe the clinical outcomes (severity of depression, severity of suicidality \& frequency of suicidal thinking, suicide events) and quality of life (QoL) of participants with symptoms of major…
- Trial name
- POWER (NCT04829669)
- Sponsor
- Janssen-Cilag Ltd.
Major Depressive Disorder
ECT Pulse Amplitude and Medial Temporal Lobe Engagement
Electroconvulsive therapy (ECT) remains the gold-standard treatment for patients with depressive episodes. During a typical four-week ECT series, most depressive episodes will respond to treatment and people will improve their…
- Trial name
- NCT02999269
- Testing
- MECTA Spectrum 5000Q Amplitude
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of New Mexico
Anxiety Depression, HIV/AIDS
Acupuncture Therapy VS Chiropractor Group Therapy to Reduce Anxiety and Depression.
This study aims to determine and compare acupuncture therapy and chiropractor group therapy to reduce anxiety and depression among HIV/AIDS patients at Being Alive, Los Angeles.
- Trial name
- NCT05936905
- Testing
- Acupuncture, Chiropractic
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Yo San University of Traditional Chinese Medicine
Post-Traumatic Stress Disorder, Major Depressive Episode
Terrorist Attack - Continuity of Care
On November 13th 2015, a terrorist attack killed 129 victims in Paris. An emergency crisis unit (CUMP) has been activated in Paris in the days following the attack and a subunit was in charge to answer to the phone calls of…
- Trial name
- CUMP75 (NCT03770156)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Depression, Postpartum
The Effect of Magnesium on Maternal Mood, Cognitive Function, and Birth Experience
Magnesium is sometimes used to prevent seizures in the setting of hypertensive disorders of pregnancy. The primary aim of this study is to determine if women who receive magnesium are less likely to experience postpartum…
- Trial name
- NCT02454322
- Testing
- Magnesium Sulfate
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Northwestern University