Clinical trials: Depression, Anxiety
Medication Adherence, Depressive Symptoms
Testing THRIVE 365 for Black Sexual Minority Men (On The Daily)
The primary goal of this study is to test a minority stress model of psychological health outcomes for Black sexual minority men (BSMM) while using and not using a novel intervention named THRIVE 365.
- Conditions
- Medication Adherence, Depressive Symptoms, Anxiety Symptoms, Emotion Regulation
- Trial name
- OTD (NCT05376397)
- Testing
- iTHRIVE 365
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Anxiety Depression
Mobile Health and COVID-19
The proposed research focuses on evaluating the mobile application, Easing Anxiety Sensitivity for Everyone (EASE), to improve overall public health that concerns risks and mental health status during the coronavirus disease of…
- Trial name
- NCT05074693
- Testing
- EASE app, INSIGHT (Control) App
- Where
- 2 sites in United States
- Volunteers
- 822 people, healthy volunteers welcome
- Sponsor
- University of Houston
Depression, Postpartum, Efficacy, Self
A Dyadic Approach to Perinatal Depression in Primary Care: Maternal Infant and Dyadic Care
The purpose of this study is to assess the effectiveness of a parenting intervention+usual care compared to usual care on postpartum depression and other mental health and parenting outcomes, as well as the feasibility and…
- Conditions
- Depression, Postpartum, Efficacy, Self, Anxiety
- Trial name
- MInD (NCT04998721)
- Testing
- Promoting First Relationships-Brief, Perinatal Integrated Care
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Washington
Cognitive Impairment, Mild, Depressive Symptoms
Brain Stimulation and Enhancing Cognition in Older Adults
The aim of the current research is to evaluate the efficacy of a combination of Mindfulness-Based Stress Reduction (MBSR) and transcranial direct current stimulation (tDCS) to improve cognitive function in individuals with…
- Conditions
- Cognitive Impairment, Mild, Depressive Symptoms, Anxiety
- Trial name
- NCT03653351
- Testing
- Active Transcranial Direct Current Stimulation (tDCS)
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- Washington University School of Medicine
Anxiety Disorders, Depression
Personalized Feedback for Distress Intolerant Smokers
This project will develop and refine a computer-delivered integrated Personalized Feedback Intervention (PFI) that directly addresses smoking and distress tolerance.
- Conditions
- Anxiety Disorders, Depression, Psychological Distress, Tobacco Dependence
- Trial name
- NCT03918031
- Testing
- PFI for Smoking & Distress Tolerance, PFI for Smoking Only
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- University of Houston
Depression, Anxiety
Technology Enabled Services to Enhance Depression Care
This study will compare two digital mental health interventions (DMHIs). One DMHI will use an app called Vira (which is a product developed and managed by Ksana Health), along with low intensity coaching provided via phone and…
- Trial name
- NCT05406791
- Testing
- VIRA App, Mood Education App
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Northwestern University
Anxiety Depression, Disability Physical
Exploratory Study for Toivoa-001 on Human Factors
The Study will evaluate Rauha as an experimental digital therapeutic for persons with Disabilities suffering from anxiety and/or depression.
- Trial name
- NCT06477913
- Testing
- Rauha
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Toivoa Inc
Anxiety Disorder, Cognitive/Functional Effects
Health Education Materials With/Out a Physical Activity Program for Patients Who Have Undergone Treatment for High-Risk Stage II or Stage III Colon Cancer
RATIONALE: Participating in a physical activity program designed to increase free time physical activity and receiving written health education materials may influence the chance of cancer recurring as well as impact on physical…
- Conditions
- Anxiety Disorder, Cognitive/Functional Effects, Colorectal Cancer, Depression
- Trial name
- CHALLENGE (NCT00819208)
- Testing
- exercise intervention, counseling intervention, educational intervention
- Where
- 47 sites in United States, Australia and 4 more
- Volunteers
- 889 people
- Sponsor
- Canadian Cancer Trials Group
Depression, Anxiety
Epidemiology of Depression, Anxiety, and Cognitive Impairment
Many older adults have undetected health problems and lack basic prevention measures. Failure to identify and treat these conditions can lead to unnecessary morbidity and mortality and a decreased quality of life.
- Conditions
- Depression, Anxiety, Cognitive Impairment
- Trial name
- NCT00717041
- Where
- United States
- Volunteers
- 1,206 people
- Sponsor
- University of Rochester
Depression, Anxiety
Modulating Default Mode Network Function: A Transcranial Direct Current Stimulation (TDCS) Pilot Study
The primary purpose of this research is to gather scientific information about how different people's brains work when they look at different types of pictures.
- Trial name
- MDMN (NCT04598152)
- Testing
- TDCS - transcranial direct current stimulation
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Jay Fournier
Post-traumatic Stress Disorder, Traumatic Brain Injury
Multisite RCT of STEP-Home: A Transdiagnostic Skill-based Community Reintegration Workshop
In this proposal, the investigators extend their previous SPiRE feasibility and preliminary effectiveness study to examine STEP-Home efficacy in a RCT design.
- Conditions
- Post-traumatic Stress Disorder, Traumatic Brain Injury, Substance Related Disorders, Depression
- Trial name
- STEP-Home (NCT03868930)
- Testing
- STEP-Home, PCGT
- Where
- 2 sites in United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
COVID-19, Pregnancy Complications
Health and Wellbeing of Pregnant and Post-Partum Women During the COVID-19 Pandemic
The purpose of this study is to assess the health and wellbeing of pregnant and recently pregnant women during the COVID-19 pandemic using an online survey.
- Conditions
- COVID-19, Pregnancy Complications, Mental Health Wellness 1, Anxiety
- Trial name
- NCT04385238
- Testing
- This is an online survey with no intervention.
- Where
- United States
- Volunteers
- 6,894 people
- Sponsor
- Pregistry
Anxiety Disorders, Depressive Disorder
Harnessing Mobile Technology to Reduce Mental Health Disorders in College Populations
The prevalence of mental health problems among college populations has risen steadily in recent decades, with one third of today's students struggling with anxiety, depression, or an eating disorder (ED).
- Conditions
- Anxiety Disorders, Depressive Disorder, Eating Disorders
- Trial name
- iAIM EDU (NCT04162847)
- Testing
- SilverCloud Health Intervention
- Where
- 4 sites in United States
- Volunteers
- 6,205 people
- Sponsor
- Washington University School of Medicine
Anxiety Disorders
Expectation of Unpleasant Events in Anxiety Disorders
Fear and anxiety are normal responses to a threat. However, anxiety is considered abnormal when the response to the threat is excessive or inappropriate.
- Trial name
- NCT00055224
- Testing
- Threat of shock
- Where
- United States
- Volunteers
- 921 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Depression, Anxiety
A Transdiagnostic Course for Common Mental Health Problems in Primary Care
This study investigates the feasibility of a transdiagnostic course that is intended to work for a large variety of patient groups with clinically significant depression or anxiety in primary care.
- Trial name
- NCT04522713
- Testing
- Behavioral activation, evidence-based sleep strategies including sleep restriction, exposure-based strategies, promotion of physical activity and recuperating activities, psychoeducational material
- Where
- 2 sites in Sweden
- Volunteers
- 91 people
- Sponsor
- Karolinska Institutet
Cancer, Quality of Life
The PRISM Intervention: a Multi-site Randomized Controlled Trial for Adolescents and Young Adults With Advanced Cancer
Multi-Site Randomized Controlled Trial testing the efficacy of the Promoting Resilience in Stress Management (PRISM) intervention among Adolescents and Young Adults with Advanced Cancer
- Conditions
- Cancer, Quality of Life, Anxiety, Depression
- Trial name
- PRISM-AC (NCT03668223)
- Testing
- Promoting Resilience in Stress Management (PRISM)
- Where
- 5 sites in United States
- Volunteers
- 269 people
- Sponsor
- Dana-Farber Cancer Institute
Cardiac Failure, Heart Failure
Insomnia Self-Management in Heart Failure
Chronic insomnia may contribute to the development and exacerbation of heart failure (HF), incident mortality and contributes to common and disabling symptoms (fatigue, dyspnea, anxiety, depression, excessive daytime sleepiness…
- Conditions
- Cardiac Failure, Heart Failure, Congestive Heart Failure, Heart Failure, Congestive
- Trial name
- HSS (NCT02660385)
- Testing
- Cognitive Behavioral Therapy for Insomnia, Self-Management Education for Heart Failure
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- Yale University
Depressive Disorder, Anxiety Disorder
Pharmacokinetics and Tolerability of Vortioxetine (Lu AA21004) in Child and Adolescent Patients With Depressive or Anxiety Disorder
The objective of the study is to evaluate the pharmacokinetics of vortioxetine and its metabolites in connection with multiple oral dosing in child and adolescent patients with a DSM-IV-TR diagnosis of Depressive or Anxiety…
- Trial name
- NCT01491035
- Testing
- Vortioxetine
- Where
- 7 sites in United States, Germany
- Volunteers
- 48 people
- Sponsor
- H. Lundbeck A/S
Symptoms of Depression and Anxiety
Mindfulness Intervention Using Virtual Reality in Older Adults With Symptoms of Anxiety and Depression in Ecuador
The availability of affordable hardware and rapidly growing content that can be freely accessed in the public domain raises the possibility of VR being used across the world globally and, in a very broad range of settings…
- Trial name
- NCT06219642
- Testing
- Mindfulness using virtual reality
- Where
- Ecuador
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Universidad San Francisco de Quito
Depression, Depression in Old Age
Trial to Test Effectiveness of Depression Intervention for Mistreated Older Adults
The investigators developed EM/PROTECT, a behavioral intervention for depressed EM (elderly mistreatment) victims, to work in synergy with EM mistreatment resolution services that provide safety planning, support services, and…
- Conditions
- Depression, Depression in Old Age, Elder Abuse, Anxiety
- Trial name
- NCT04258579
- Testing
- PROTECT with Technology Augmentation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Weill Medical College of Cornell University