Clinical trials: Denture Retention
Denture Retention
A Clinical Study to Assess the Effectiveness of Use of Three Experimental Denture Adhesives Compared to Using No-Adhesive
The aim of the proposed clinical study is to investigate the efficacy of three experimental denture adhesive creams to improve denture hold over a period of 13 hours.
- Trial name
- NCT07496164
- Testing
- Experimental Denture Adhesive 1, Experimental Denture Adhesive 2, Experimental Denture Adhesive 3
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- HALEON
Denture Retention
A Study to Assess the Effectiveness of a Marketed Denture Adhesive in Real-World Setting
The purpose of this decentralised study in a real-world setting is to assess the effectiveness of a marketed denture adhesive (Poligrip Power Max Hold + Seal) in preventing food entrapment under dentures (self-assessed).
- Trial name
- NCT07273149
- Testing
- Poligrip Power Max Hold + Seal
- Where
- United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- HALEON
Denture Retention
A Clinical Study to Evaluate the Maximum Maxillary Bite Force (BF) When Using Two Novel Denture Adhesives Compared to Using No-Adhesive
The purpose of this study is to investigate the hold properties of two experimental denture adhesives using established maximum incisal BF methodology.
- Trial name
- NCT05173974
- Testing
- Super Poligrip Free, Experimental Denture Adhesive 1, Experimental Denture Adhesive 2
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- HALEON
Denture Retention
To Evaluate Oral Health and Quality of Life Associated With Use of a Denture Adhesive
The aim of this study is to evaluate the use of a denture adhesive and its ability to demonstrate the improvement in overall gum-health and to improve the oral health related quality of life (OHrQoL) in participants who wear full…
- Trial name
- NCT03807700
- Testing
- Experimental Denture Adhesive
- Where
- Canada
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Denture Retention
A Clinical Study to Assess Force Required to Dislodge Upper Denture With and Without Use of a Novel Denture Adhesive
The purpose of this study is to investigate the hold properties of an investigational denture adhesive using an established methodology called the maximum incisal bite force (BF), and Kapur-Olshan (KO) index for denture retention…
- Trial name
- NCT04473521
- Testing
- Investigational denture adhesive cream, Super Poligrip Free
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Denture Retention
A Study to Investigate Food Occlusion Efficacy of a Denture Adhesive in Denture Wearers
The purpose of this study is to determine the ability of a marketed denture adhesive to restrict food ingress underneath dentures during eating.
- Trial name
- NCT03709810
- Testing
- Marketed Denture Adhesive (Super Poligrip Max Seal), No Adhesive
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- GlaxoSmithKline
Denture Retention
A Study to Investigate a Method to Measure Food Occlusion by Denture Adhesives in Denture Wearers
The purpose of this study is to evaluate a methodology to determine the ability of a denture adhesive to restrict food ingress underneath dentures during eating.
- Trial name
- NCT03345108
- Testing
- Denture Adhesive Cream (Conventional Application), Denture Adhesive (Continuous Strip Application), No Adhesive
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Denture Retention
A Clinical Bite Force Study of Two Marketed Adhesives Against no Adhesive
The objective of this study will be to compare bite force (BF) measurements over a 12-hour period of a currently marketed denture adhesive cream based on carbomer technology (test), with a positive control and a negative/no…
- Trial name
- NCT03037307
- Testing
- Test Product, Positive Contol, Negative Control
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Denture Retention
Evaluation of a Experimental Denture Adhesive to Prevent Food Ingress
In this clinical study, an experimental denture adhesive with a precision tip nozzle was tested to evaluate the relative efficacy to reduce the ingress of food under the denture compared to use of no adhesive or a standard…
- Trial name
- NCT02928380
- Testing
- Experimental Denture Adhesive, Reference (Marketed) Denture Adhesive
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Denture Retention
A Bite Force Study Comparing Two New Test Adhesives With Currently Marketed Denture Adhesive
The objective of this 4-treatment, 4-period, randomized, crossover, proof of principle bite force study will be to compare bite force measurements over a 12 hour period across two (test) cream denture adhesives, with a currently…
- Trial name
- NCT02937870
- Testing
- Test Product 1, Test Product 2, Reference Product
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline