Clinical trials: Dentin Sensitivity
Inflammation, Pulpitis
Assessing of Tooth Sensitivity Using Ibuprofen Before in Office-tooth Bleaching
Ibuprofen has been recognized as anti-inflammatory and analgesic. The purpose of this study is to determine the effect of ibuprofen 400 mg on tooth sensitivity (TS) caused by in-office bleaching.
- Trial name
- NCT01530217
- Testing
- Ibuprofen.
- Volunteers
- 30 people
- Sponsor
- Universidade Estadual de Ponta Grossa
Dentin Sensitivity
Study to Investigate the Efficacy of an Occluding Dentifrice in Providing Relief From Dentine Hypersensitivity
This will be a single centre, two week, randomised, examiner blind, two treatment arm, parallel design, stratified (by maximum baseline Schiff sensitivity score of the two selected test teeth), controlled study, in participant…
- Trial name
- NCT02773758
- Testing
- Stannous Fluoride Dentifrice, Sodium monofluorophosphate Dentifrice
- Where
- Canada
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentin Sensitivity
Efficacy of Two Experimental Oral Rinses in Providing Long Term Relief From Dentinal Hypersensitivity
This study will investigate the longitudinal efficacy of two experimental oral rinses containing 1.5% weight/weight (w/w) dipotassium oxalate monohydride (KOX), formulated at pH 4.5 and pH 7 respectively, for the relief of…
- Trial name
- NCT02542943
- Testing
- Experimental Oral Rinse 1, Experimental Oral Rinse 2, Standard fluoride toothpaste
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Tooth Sensitivity
Diode Low-power Laser Before In-office Bleaching
Background: The aim of study was to investigate the effectiveness of low-level laser therapy (LLLT) use before in-office bleaching to prevent risk and intensity of tooth sensitivity.
- Trial name
- NCT05865275
- Testing
- Low-level laser treatment, tooth bleaching procedure
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Tooth Discoloration
Effects of Bio-active Desensitizer on Reduction of Tooth Sensitivity Caused by In-office Bleaching.
The main aim of this randomized controlled clinical trial is to evaluate the efficacy of a bioactive glass desensitizer in reducing tooth sensitivity associated with in-office vital tooth bleaching.
- Trial name
- NCT06532526
- Testing
- Predicta® Bioactive Desensitizer (PBD, PARKELL, EDGEWOOD, NY, USA), Gel with 1.23% sodium fluoride (EAZIGEL, VERICOM CO., LTD. SOUTH KOREA)
- Where
- Jordan
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Dentine Hypersensitivity
Comparision of the Clinical Efficacy of Different Desensitizing Toothpastes
Dentin hypersensitivity is a common problem in society. Untreated hypersensitivity affects the patient's quality of life, complicates plaque control and increases the risk of caries and periodontal disease.
- Trial name
- NCT06197555
- Testing
- Sodium Monofluorophosphate, Stannous Fluoride, Nano-Hydroxyapatite
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Altinbas University
Enamel Hypomineralization, Tooth Erosion
Hydroxyapatite Toothpastes and Enamel Remineralization:
This randomized controlled clinical trial aims to evaluate the efficacy of two commercially available toothpastes containing hydroxyapatite in the remineralization of early enamel lesions.
- Trial name
- HEREMI (NCT07069218)
- Testing
- Biorepair® Total Protection Plus Toothpaste, Bioniq® Toothpaste
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Pavia
Pain, Dentin Sensitivity
Effect of an Experimental Gel Containing Copaiba Oil-resin in the Control of Dentin Hypersensitivity
This randomized, single-blind, placebo-controlled clinical trial aims to clinically evaluate the effect of an experimental gel containing copaiba oleo-resin in the control of dentin hypersensitivity (DH) in non-carious cervical…
- Conditions
- Pain, Dentin Sensitivity, Dentin Desensitizing Agents
- Trial name
- NCT06872749
- Testing
- KF2 (Potassium nitrate gel), experimental Copaiba gel
- Where
- Brazil
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Dentinal Hypersensitivity, Plaque, Dental
Evaluation of Dental and Periodontal Health After IPR in Patients in Orthodontic Treatment With Clear Aligners
This study aimed to evaluate dental and periodontal health after interproximal enamel reduction and to compare Laser diode (a device used in the Orthodontic Program) and sodium fluoride (often used in the Orthodontic Program and…
- Conditions
- Dentinal Hypersensitivity, Plaque, Dental, Bleeding Gum
- Trial name
- NCT06685016
- Testing
- Evaluation of Dentin hypersensitivity with VAS scale
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Dentin Sensitivity
Nano-hydroxyapatite With Potassium Nitrate in the Therapy of the Dental Sensitivity
The chief aim of this study is to evaluate the difference in tooth sensitivity after having used a gel containing nano - hydroxyapatite and potassium nitrate This randomized double-blind clinical study is designed to compare the…
- Trial name
- NCT02895321
- Testing
- Cavex Bite&White ExSense, Colgate, Protection Caries
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- Università degli Studi di Sassari
Color, Bleaching Sensitivity
Whitening Efficacy and Tooth Sensitivity of Different Concentrations of Hydrogen Peroxide Photoactivated With Violet or Blue LEDs
This is a randomized, controlled, double-blind and repeated-measures clinical trial evaluated the photoactivation of hydrogen peroxide gels in different concentrations with blue or violet LED in terms of whitening efficacy and…
- Trial name
- NCT06165458
- Testing
- 6% hydrogen peroxide gel + violet LED, 6% hydrogen peroxide gel + blue LED, 35% hydrogen peroxide gel + violet LED
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Dentin Hypersensitivity, Tooth Hypersensitivity
Diode Laser Plus CPP-ACPF vs CPP-ACPF Alone for Dentin Hypersensitivity
This study aims to compare the effectiveness of diode laser photobiomodulation combined with CPP-ACPF varnish versus CPP-ACPF varnish alone in reducing dentin hypersensitivity.
- Trial name
- NCT07449169
- Testing
- Diode laser photobiomodulation combined with CPP-ACPF varnish, CPP-ACPF varnish
- Volunteers
- 70 people
- Sponsor
- Cairo University
Dentin Sensitivity
Effect of Glutaraldehyde on Dentin Hypersensitivity After Non-surgical Periodontal Treatment
This randomized, placebo-controlled, triple-blind trial aims to evaluate the effect of glutaraldehyde associated or not with 37% phosphoric acid conditioning on dentin hypersensitivity reduction after non-surgical periodontal…
- Trial name
- NCT04207450
- Testing
- Phosphoric Acid 37% + Solução aquosa de glutaraldeído a 5%
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Dentin Hypersensitivity, Dentin Desensitizing Agents
Effectiveness of Two Different Desensitizing Dental Varnishes
Dental varnishes are commonly used to relieve dentin hypersensitivity by forming a protective film that occludes dentinal tubules and reduces fluid flow.
- Trial name
- NCT07622043
- Testing
- Fluoride-containing varnish, Fluoride-free varnish
- Where
- Liechtenstein
- Volunteers
- 66 people
- Sponsor
- Ivoclar Vivadent AG
Tooth Bleaching, Pain
Efficacy of an Experimental Gel Based on Libidibia Ferrea on Post-bleaching Tooth Sensitivity
This randomized, parallel, single-blind, placebo-controlled clinical trial aims to investigate the effects of an experimental 0.5% Libidibia ferrea gel on the control of post-bleaching tooth sensitivity and its influence on…
- Conditions
- Tooth Bleaching, Pain, Dentin Desensitizing Agents
- Trial name
- NCT07599514
- Testing
- KF2 - Potassium nitrate, Jucá - Libidibia ferrea gel
- Where
- Brazil
- Volunteers
- 75 people
- Sponsor
- Universidade Federal do Para
Dentin Hypersensitivity
Evaluation of Biomimetic Mineralization Plus Soft Laser Irradiation in Dentin Hypersensitivity Management
Randomized clinical trial to investigate the efficacy of diode laser , Biomimetic mineralization desensitizing agents Curodont D'Senz (CS) gel both in combination and alone, and the efficacy of bifluoride 10 (5 % sodium fluoride)…
- Trial name
- Rct (NCT06829277)
- Testing
- Sodium fluoride varnish, Curodont De Senz, Curodont De Senz plus laser irradiation
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- MTI University
Dentin Hypersensitivity
The Efficacy of a Toothpaste to Reduce Sensitivity
Hypersensitivity
- Trial name
- NCT00763269
- Testing
- Triclosan, Silicon dioxide, fluoride, Triclosan, fluoride
- Where
- United States
- Volunteers
- 626 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dentin Sensitivity, Tooth Bleaching
Evaluation of Sensitivity With and Without Sonic Activation of a Desensitizing Gel Before in Office Bleaching in Adults
This randomized, controlled clinical trial, triple-blind, split-mouth type was conducted aiming to assess the absolute risk of sensitivity with and without sonic activation of a desensitizing gel previously to the in-office…
- Trial name
- NCT03039270
- Testing
- With sonic activation (SMART Device®), Control (Without sonic activation)
- Where
- Brazil
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Federal University of Amazonas