Clinical trials: Dentin Hypersensitivity
Dentin Sensitivity, Dentin Hypersensitivity
Efficacy of a Sonic Toothbrush and 8% Arginine Toothpaste in Reducing Dentinal Hypersensitivity
This clinical study evaluates the efficacy of an oral hygiene regimen consisting of an electric sonic toothbrush used in combination with an 8.0% arginine and calcium carbonate toothpaste in reducing dentinal hypersensitivity…
- Trial name
- NCT07871786
- Testing
- 8.0% Arginine Dentifrice, Electric Sonic Toothbrush, Adult Soft Bristle Manual Toothbrush
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Colgate Palmolive
Dentin Hypersensitivity
Clinical Study to Investigate the Antihypersensitivity Efficacy of a Novel Dentifrice
The aim of this clinical study is to demonstrate the superior antihypersensitivity efficacy of a novel stannous fluoride (SnF2) and potassium nitrate (KNO3) dentifrice (Investigational Product), compared to SnF2 only, KNO3 only…
- Trial name
- NCT07215767
- Testing
- Stannous fluoride and Potassium nitrate Dentifrice, Stannous fluoride Dentifrice, Potassium nitrate Dentifrice
- Where
- 3 sites in United States
- Volunteers
- 688 people, healthy volunteers welcome
- Sponsor
- HALEON
Dentin Hypersensitivity, Dentin Desensitizing Agents
Effectiveness of Two Different Desensitizing Dental Varnishes
Dental varnishes are commonly used to relieve dentin hypersensitivity by forming a protective film that occludes dentinal tubules and reduces fluid flow.
- Trial name
- NCT07622043
- Testing
- Fluoride-containing varnish, Fluoride-free varnish
- Where
- Liechtenstein
- Volunteers
- 66 people
- Sponsor
- Ivoclar Vivadent AG
Dentine Hypersensitivity
Study to Investigate the Effect of Changes in Dentinal Hypersensitivity on Oral Health Parameters
This exploratory study will investigate the effect of long-term management of Dentine Hypersensitivity (DH) by use of a sensitivity toothpaste on selected oral health parameters, such as changes in oral hygiene (as measured by…
- Trial name
- NCT07768969
- Testing
- Test Toothpaste
- Where
- United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- HALEON
Dentinal Sensitivity, Dentinal Hypersensitivity
Comparative Efficacy of Different Dentin Occluding Toothpaste Technologies
The purpose of this clinical study is to evaluate and compare how well three different types of toothpaste technologies work to relieve tooth sensitivity, also known as dentin hypersensitivity.
- Trial name
- SENSBZ (NCT07664592)
- Testing
- 8% arginine + Zinc toothpaste, 5% Calcium Sodium Phosphosilicate toothpaste, 8% arginine toothpaste
- Where
- Brazil
- Volunteers
- 132 people
- Sponsor
- Colgate Palmolive
Dentine Hypersensitivity
A Study to Evaluate the Dentinal Hypersensitivity Efficacy of Two Experimental Mouthwash Formulations
The aim of this study is to evaluate the clinical efficacy of two experimental mouthwash formulations, against a placebo mouthwash (without experimental ingredients).
- Trial name
- NCT07741032
- Testing
- 3% KNO3 Mouthwash, 2% HPC Mouthwash, 0% KNO3 Mouthwash
- Where
- Germany
- Volunteers
- 118 people
- Sponsor
- HALEON
Dentin Hypersensitivity
A Study Evaluating Oral-Health-Related Quality of Life and Treatment Patterns Among Dentin Hypersensitivity Sufferers
The primary purpose of this study is to characterize changes in Oral-Health-Related Quality of Life (OHrQoL), as measured by the Dentin Hypersensitivity Experience Questionnaire (DHEQ) over a 12-month period.
- Trial name
- NCT07337109
- Where
- United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- HALEON
Dentin Hypersensitivity
A Study to Investigate the Tooth Whitening and Dentin Hypersensitivity Effectiveness of Two Experimental Toothpastes
The aim of this exploratory clinical study is to investigate the tooth whitening potential, Dentin Hypersensitivity (DH) efficacy, and oral tolerability of two experimental toothpastes in a DH population with appropriate tooth…
- Trial name
- NCT07297732
- Testing
- Test Toothpaste 1, Test Toothpaste 2, Reference Toothpaste
- Where
- United States
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- HALEON
Dentin Hypersensitivity
Hypersensitivity Reduction Efficacy: 5% Potassium Nitrate Toothpaste Compared to Colgate Cavity Protection Toothpaste
Assess the clinical efficacy of 5% Potassium Nitrate Toothpaste (Colgate-Palmolive Company, New York, NY, USA) on providing dentinal hypersensitivity relief (tactile and air blast) in comparison to Colgate Cavity Protection…
- Trial name
- NCT06956599
- Testing
- test toothpaste, Control toothpaste
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Sensitivity, Tooth
Dentinal Hypersensitivity Reduction Efficacy Study
Assess the clinical efficacy of CSPR Toothpaste containing 8% arginine to provide dentinal hypersensitivity relief
- Trial name
- NCT06960148
- Testing
- CSPR Toothpaste, Colgate Dental Cream Toothpaste
- Where
- China
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dentinal Hypersensitivity
Dentinal Hypersensitivity Reduction
The objective of this clinical study is to assess the efficacy of a dentifrice containing stannous fluoride (Colgate-Palmolive Company, New York, NY, USA) as compared to a commercially-available potassium-based toothpaste…
- Trial name
- NCT06244290
- Testing
- Colgate SNF, Sensodyne Extra Whitening, Colgate Fluoride (CDC)
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dentin Hypersensitivity
Phase 2 Study of KH001 in Long-term Relief From Dentin Hypersensitivity
The purpose of this study is to evaluate the efficacy and safety of KH001 in subjects with dentin hypersensitivity.
- Trial name
- NCT06464939
- Testing
- KH001
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- HysensBio Co., Ltd
Dentin Hypersensitivity
A Study to Evaluate the Efficacy and Safety of KH001 in Patients with Dentin Hypersensitivity
The purpose of this study is to evaluate the efficacy and safety of KH001 in patients with dentin hypersensitivity.
- Trial name
- NCT06264453
- Testing
- KH001
- Where
- South Korea
- Volunteers
- 171 people
- Sponsor
- HysensBio Co., Ltd
Dentin Sensitivity
Evaluation of the Safety and Tolerability of KH001 in Dentin Hypersensitivity Patients
This is a phase 1/2a study in dentin hypersensitivity patients to assess the safety, tolerability, efficacy and pharmacokinetics of single and multiple doses of KH001.
- Trial name
- NCT04804514
- Testing
- KH001
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- HysensBio Co., Ltd
Dentin Hypersensitivity
A Comparison Study of Hypersensitivity Treatment
The goal of this clinical trial is to evaluate the effect of 3M™ Clinpro™ Fluoride Aqueous Solution (experimental) on Dentin Hypersensitivity (DHS) in comparison to 3M™ Vanish™ (commercialized, control] in patients who have DHS.
- Trial name
- NCT05768373
- Testing
- 3M™ Clinpro™ Fluoride Aqueous Solution, 3M™ Vanish™
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Solventum US LLC
Dentinal Hypersensitivity
Efficacy of Sensi-IP Toothpaste in the Treatment of Dentinal Hypersensitivity Compared to a Sodium Fluoride Toothpaste
The study is designed as a prospective, randomized, parallel arm, double blinded, pilot clinical trial.The primary objective is to evaluate the efficacy of Sensi-IP +NaF as compared to a NaF toothpaste in the reduction of dentin…
- Trial name
- NCT06166745
- Testing
- Sensi-IP toothpaste, Sodium Fluoride Toothpaste
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- IR Scientific Inc.
Dentin Hypersensitivity
The Effect of the Egg Shell Nanoparticles Combined With Titanium Dioxide Nanoparticles
Dentin hypersensitivity is one of the most commonly occurring clinical dental conditions which is characterized by short and sharp pain which arises from exposed dentin in response to external stimuli, which typically are…
- Trial name
- NCT06025084
- Testing
- Egg Shell nanoparticles
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Egymedicalpedia
Dentin Hypersensitivity
A Clinical Study to Assess the Effects of Various Dentifrice Technologies on Dentinal Hypersensitivity
The objective of this study is to evaluate the efficacy (changes in dentinal hypersensitivity) and safety (oral soft tissue evaluation) after use of one of four dentifrices in subjects with pre-existing hypersensitivity over an…
- Trial name
- NCT03965039
- Testing
- Dipotassium oxalate toothpaste, Stannous fluoride toothpaste, Potassium nitrate toothpaste
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Dentin Sensitivity
Effectiveness of Two Water-Based Potassium Oxalate Desensitizers on Dental Hypersensitivity
This study will compare the safety and effectiveness of two water-based potassium oxalate desensitizers on existing dentinal hypersensitivity.
- Trial name
- NCT02152826
- Testing
- Potassium oxalate
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Dentin Hypersensitivity, Dentin Sensitivity
Study to Characterize the Efficacy of a Dual Active Dentifrice for the Relief of Dentin Hypersensitivity
This exploratory study will characterize the efficacy profile of an experimental dual active 5 percent (%) potassium nitrate/0.454% stannous fluoride dentifrice, compared to a single active 0.454% stannous fluoride desensitizing…
- Trial name
- NCT03943095
- Testing
- Potassium Nitrate, Stannous Fluoride
- Where
- Canada
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline