Clinical trials: Dental Sedation
Caries of Infancy, Dental Anxiety
Intranasal Sedation With Dexmedetomidine and Ketamine in Pediatric Dentistry (NASO II)
Parallel clinical trial focusing on procedural pediatric sedation in the dental setting. Children will be randomized to treatment according to a predetermined sequence of interventions consisting of: 1.
- Trial name
- NCT03290625
- Testing
- Dexmedetomidine Hydrochloride, Ketamine Hydrochloride
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Dental Anxiety
Efficacy of Oral Midazolam for Sedation and Amnesia in Preschool Children Undergoing Dental Procedures
Dental anxiety frequently impedes effective dental care in pediatric patients. This study aimed to compare the efficacy and safety of two doses (0.3 mg/kg and 0.6 mg/kg) of oral midazolam for sedation and amnesia in preschool…
- Trial name
- NCT06887712
- Testing
- Oral midazolam
- Where
- Vietnam
- Volunteers
- 80 people
- Sponsor
- Hanoi Medical University
Anxiety, Dental, Dental Decay
A Comparison of Oral Sedation-related Events of Three Multiagent Oral Sedation Regimens in Pediatric Dental Patients
This study will compare the post sedation events from three different multi-drug oral sedation regimens in order to help pediatric dentists determine the best course of action for their patients and prepare parents appropriately…
- Trial name
- NCT05126459
- Testing
- Regimen 1, Regimen #2, Regimen #3
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Loma Linda University
Dental Anxiety, Blood Pressure
Valerian for Conscious Sedation in Patients Submitted to Impacted Lower Third Molars Surgery
The aim of the present study was to evaluate the efficacy of Valeriana officinalis L. 100 mg in single oral doses one hour preoperative as conscious sedation during the impacted lower third molar surgery.
- Conditions
- Dental Anxiety, Blood Pressure, Heart Rate
- Trial name
- NCT01612130
- Testing
- 100 mg of Valeriana officinalis L
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Federal University of the Valleys of Jequitinhonha and Mucuri
Anxiety, Pain
Bispectral Index and Clinical Parameters Evaluation in Dental Procedures
BACKGROUND: The degree of consciousness during nitrous oxide use is still a matter of concern for both dentists and anesthesiologists.
- Trial name
- BIS-01 (NCT02671578)
- Testing
- Nitrous Oxide
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Francisco Groppo
Dental Sedation, Passive Smoking
The Effects of Passive Smoking on Vital Signs, Anxiety, and Recovery Times in Children Undergoing Primary Tooth Extraction Treatment Under Sedation
The aim of this clinical study is to evaluate the effects of passive smoking on the vital parameters of children undergoing primary tooth extraction under sedation and to assess their anxiety levels throughout the process until…
- Trial name
- NCT06780189
- Testing
- Tooth Extraction and Post-Procedure Monitoring Under Sedation in Children Exposed to Passive Smoking, Tooth Extraction and Post-Procedure Monitoring Under Sedation in Children Not Exposed to Passive Smoking
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Dental Care for Children
Evaluation Ofe the Anxiolytic Effect of EMONO in Children During Dental Care (MOPEA)
The EquiMolar Oxygen and Nitrous Oxyde mix (EMONO) is listed by the ANSM (National Agency for the Safety of Medicines and Health Products) as drugs with enhanced surveillance.
- Trial name
- MOPEA (NCT03998774)
- Testing
- Evaluate the anxiolytic effect during dental care with MEOPA in children
- Where
- France
- Volunteers
- 17 people
- Sponsor
- Nantes University Hospital
Blood Gas Monitoring, Transcutaneous
Biphasic Extrathoracic Cuirass Ventilation During Dental Treatment
The MRTX portable lightweight respirator (MRTX) provides noninvasive respiratory support using biphasic extrathoracic ventilation via a cuirass fitted around the patient's chest.The aim of the study is to evaluate the efficacy of…
- Trial name
- NCT00420069
- Testing
- MRTX device
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Child Behavior, Dental Caries in Children
Sedation Versus Protective Stabilization for Pediatric Dental Treatment
There is a lack of evidence on the effectiveness of moderate sedation in pediatric dentistry, compared to protective stabilization, which remains routinely used in the Brazilian context despite moral questions.
- Trial name
- NCT04119180
- Testing
- Ketamine 50 MG/ML, Midazolam Hcl 2Mg/Ml Syrup, Protective stabilization
- Where
- 2 sites in Brazil
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Dental Extraction
Use of Remimazolam and Fentanyl for Procedural Sedation in Patients Undergoing Dental Extraction
The goal of this clinical trial is to learn if a combination of the two established sedation drugs remimazolam and fentanyl, can put the subject to sleep during a scheduled extraction procedure.
- Trial name
- NCT06793358
- Testing
- fentanyl and Remimazolam
- Where
- United States
- Sponsor
- Indiana University
Dental Anxiety
Midazolam Sedation in Dentally Anxious Patients
Use lay language. To compare patient level of cooperation during dental care under conscious sedation with midazolam according to the administration route
- Trial name
- NCT01874717
- Testing
- Conscious sedation for dental care, midazolam
- Where
- France
- Volunteers
- 131 people
- Sponsor
- University Hospital, Clermont-Ferrand
Dental Anxiety
The Impact of Nitrous Oxide Sedation on Dental Fear and Anxiety Scores in Children Aged 6-10 Years
Dental anxiety (DA) is highly prevalent among children undergoing dental procedures, with 50-80% experiencing fear that disrupts treatment and exacerbates oral health outcomes.
- Trial name
- N₂O (NCT07384988)
- Testing
- Nitrous Oxide Sedation, psychological support
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shaoxing Maternity and Child Health Care Hospital
Dental Anxiety, Sedation Complication
Remimazolam in the Extraction of Impacted Wisdom Teeth
Benzodiazepines, represented by midazolam, are often used for sedation in outpatient surgery in dentistry. However, midazolam has the problems of slow consciousness recovery and long recovery time, which brings trouble to the…
- Conditions
- Dental Anxiety, Sedation Complication, Anterograde Amnesia
- Trial name
- NCT05350085
- Testing
- Remimazolam besylate, Midazolam
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Peking Union Medical College Hospital
Deep Sedation, Dental Treatment
High-flow Nasal Oxygenation During Deep Sedation in Pediatric Dental Patients
It is important to choose an appropriate oxygenation technique during intravenous deep sedation in pediatric dental treatment. The study is to evaluate the efficacy and safety of high-flow nasal oxygenation in intravenous deep…
- Conditions
- Deep Sedation, Dental Treatment, Pediatric Patients
- Trial name
- NCT05762692
- Testing
- High-flow nasal oxygenation device
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Peking University
Dental Caries, Tooth Extraction
Treating Children With Extensive Dental Needs
The goal of this qualitative study, using Grounded Theory, is to gain deeper knowledge about dentists' experiences from treating in particular young children with an extensive treatment need (mainly due to caries).
- Conditions
- Dental Caries, Tooth Extraction, Conscious Sedation, Attitude
- Trial name
- NCT06863103
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Malmö University
Nitrous Oxide Inhalation Sedation
Comparison of the Silhouette and Porter Brown Systems Used in Inhalation Sedation
This is a randomised non-blinded controlled clinical trial, which involves the measurement of efficiency and acceptability of the Silhouette Mask system and compares it with the Porter Brown Mask system used for Inhalation…
- Trial name
- NCT04734509
- Testing
- Silhouette breathing system
- Where
- United Kingdom
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Mental Retardation
Effect of Valproate on Propofol
The aim of this study is to evaluate the effect of valproate on the required dose of propofol for sedation in patients with mental retardation.
- Trial name
- NCT01170377
- Where
- Japan
- Volunteers
- 50 people
- Sponsor
- Okayama University
Child Behavior, Dental Caries
Midazolam and Ketamine Effect Administered Through the Nose for Sedation of Children for Dental Treatment
Randomised clinical trial to test the efficacy, safety and cost-effectiveness of sedatives; masked, controlled, parallel design with three arms, phase 4.
- Trial name
- NASO (NCT02447289)
- Testing
- Intranasal ketamine, Oral ketamine, Intranasal midazolam
- Where
- Brazil
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias