Clinical trials: Dental Sedation
Dental Anxiety
Nebulized Midazolam, Dexmedetomidine, and Their Combination in Sedation of Preschoolers Undergoing Dental Treatment
The aim of the study is to evaluate the effect of nebulized Midazolam, Dexmedetomidine, and their combination as procedural, moderate sedative agents in preschoolers undergoing dental treatment.
- Trial name
- NCT03827408
- Testing
- Midazolam group (MDZ), Dexmedetomidine group (DEX), Combination of Midazolam and Dexmedetomidine (MDZ/DEX)
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Nourhan M.Aly
Caries of Infancy, Dental Anxiety
Intranasal Sedation With Dexmedetomidine and Ketamine in Pediatric Dentistry (NASO II)
Parallel clinical trial focusing on procedural pediatric sedation in the dental setting. Children will be randomized to treatment according to a predetermined sequence of interventions consisting of: 1.
- Trial name
- NCT03290625
- Testing
- Dexmedetomidine Hydrochloride, Ketamine Hydrochloride
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Dental Anxiety, Sedation Complication
Remimazolam in the Extraction of Impacted Wisdom Teeth
Benzodiazepines, represented by midazolam, are often used for sedation in outpatient surgery in dentistry. However, midazolam has the problems of slow consciousness recovery and long recovery time, which brings trouble to the…
- Conditions
- Dental Anxiety, Sedation Complication, Anterograde Amnesia
- Trial name
- NCT05350085
- Testing
- Remimazolam besylate, Midazolam
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Peking Union Medical College Hospital
Deep Sedation, Dexmedetomidine
Intranasal Dexmedetomidine for Deep-sedated Pediatric Dental Patients
It is important to choose an appropriate analgesia/sedation technique in pediatric dental treatment. Premedication combined with intravenous anesthesia is often used in deep sedation technique for pediatric dental treatment and…
- Trial name
- NCT04509414
- Testing
- Dexmedetomidine, Midazolam
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University
Sedative Overdose
Local Anesthesia Impact on Dental Sedation
The goal of this observational study is to investigate the impact of local anesthesia in health children who were sedated for dental procedures.
- Trial name
- NCT06218173
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ankara University
Dental Caries, Tooth Extraction
Treating Children With Extensive Dental Needs
The goal of this qualitative study, using Grounded Theory, is to gain deeper knowledge about dentists' experiences from treating in particular young children with an extensive treatment need (mainly due to caries).
- Conditions
- Dental Caries, Tooth Extraction, Conscious Sedation, Attitude
- Trial name
- NCT06863103
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Malmö University
Dental Anxiety, Blood Pressure
Valerian for Conscious Sedation in Patients Submitted to Impacted Lower Third Molars Surgery
The aim of the present study was to evaluate the efficacy of Valeriana officinalis L. 100 mg in single oral doses one hour preoperative as conscious sedation during the impacted lower third molar surgery.
- Conditions
- Dental Anxiety, Blood Pressure, Heart Rate
- Trial name
- NCT01612130
- Testing
- 100 mg of Valeriana officinalis L
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Federal University of the Valleys of Jequitinhonha and Mucuri
Dental Care for Disabled
Optimization of Procedural Sedation Protocol Used for Dental Care Delivery in People With Mental Disability
The study aims to compare procedural sedation protocols, specifically applied for the delivery of regular dental care in persons with a mental disability.
- Trial name
- OptiSeDent (NCT02078336)
- Testing
- Midazolam Mylan, Lorazepam Mylan, Valium + Akineton + Dehydrobenzperidol + Atropine sulfate
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Dental Pain
Buffered Local Anesthetic
The purpose of this research study is to compare responses in children during dental injections of local anesthetic (used for numbing), while children are under deep sedation (breathing on their own, often with a loss of…
- Trial name
- NCT05757648
- Testing
- Non-buffered Anesthetic, Buffered Anesthetic, Onset
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Anxiety State, Pediatric ALL
Anxiolytic Effects of Lavender and Orange Oil
The aim of this study is to determine the possible anxiety reducing effects of lavender oil and orange oil on parents with children receiving dental care under sedation during perioperative wait.
- Conditions
- Anxiety State, Pediatric ALL, Dental Anxiety, Oil; Inhalation
- Trial name
- NCT04079309
- Testing
- Lavender/Orange
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ankara University
Dental Cares
Use of 50% Nitrous Oxide / 50% Oxygen Premix in Primary Care Dental Centers
A 50% nitrous oxide / 50% oxygen premix is administrated to the patient during the realization of dental cares. This openly clinical trial is done in 36 French primary care dental centers, especially on anxious and phobic…
- Trial name
- NCT00643838
- Testing
- Kalinox 170 bar
- Where
- France
- Volunteers
- 549 people
- Sponsor
- Air Liquide Santé International
Behavior, Child
Oral Sedation With and Without Nitrous Oxide
Aims: The objective of the current study was to evaluate the effectiveness of oral midazolam-hydroxyzine with/without nitrous oxide. Design: This was a randomized split mouth, cross over and triple-blinded clinical study.
- Trial name
- NCT03728894
- Testing
- Midazolam-hydroxyzine with 100% O2, Midazolam-hydroxyzine with 50% N2O/O2
- Where
- Syria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Latakia University
Child Behavior, Dental Caries in Children
Sedation Versus Protective Stabilization for Pediatric Dental Treatment
There is a lack of evidence on the effectiveness of moderate sedation in pediatric dentistry, compared to protective stabilization, which remains routinely used in the Brazilian context despite moral questions.
- Trial name
- NCT04119180
- Testing
- Ketamine 50 MG/ML, Midazolam Hcl 2Mg/Ml Syrup, Protective stabilization
- Where
- 2 sites in Brazil
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Dental Anxiety
Effectiveness of Children Experiencing Nitrous Oxide/Oxygen Inhalation Sedation at an Assessment Visit Before Having Treatment.
The purpose of this study is to find out the effect of experience of dental sedation at assessment on children's anxiety before the actual treatment session.
- Trial name
- NCT06056492
- Testing
- Experience of nitrous oxide sedation at assessment
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Dr Richard Balmer
Surgery
Evaluation of the Use of RELAX Glasses on Anxiety of Patients Undergoing Dental Extraction > 2 Teeth, Under Local Anesthesia, Compared With Those Not Using Glasses
The vast majority of tooth extraction surgery is performed under local anaesthetic, and can be a source of anxiety. In their 2015 article, Appukuttan et al studied the anxiety felt by 1148 patients prior to tooth extraction, and…
- Trial name
- BRIGAND (NCT06589908)
- Testing
- RELAX glasses
- Where
- France
- Volunteers
- 106 people
- Sponsor
- Centre Hospitalier de Valenciennes
Anxiety
High-Concentration Nitrous Oxide for Dental Procedural Sedation in Children
The use of nitrous oxide as a sedative agent is very common in pediatric dentistry. In concentrations up to 50% it is considered as mild sedation and it is very safe.
- Trial name
- NCT02886351
- Testing
- Nitrous Oxide
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bnai Zion Medical Center
Blood Gas Monitoring, Transcutaneous
Biphasic Extrathoracic Cuirass Ventilation During Dental Treatment
The MRTX portable lightweight respirator (MRTX) provides noninvasive respiratory support using biphasic extrathoracic ventilation via a cuirass fitted around the patient's chest.The aim of the study is to evaluate the efficacy of…
- Trial name
- NCT00420069
- Testing
- MRTX device
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Mental Retardation
Effect of Valproate on Propofol
The aim of this study is to evaluate the effect of valproate on the required dose of propofol for sedation in patients with mental retardation.
- Trial name
- NCT01170377
- Where
- Japan
- Volunteers
- 50 people
- Sponsor
- Okayama University
Anti-anxiety Agents, Moderate Sedation
Sublingual Versus Intranasal Administration of Dexmedetomidine for Sedation of Children Undergoing Dental Treatment
The aim of this study is to assess the efficacy of Dexmedetomidine drug either used sublingually or intranasally in managing healthy children during dental treatment
- Trial name
- NCT04237532
- Testing
- Intranasal Dexmedetomidine, Sublingual Dexmedetomidine
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Nourhan M.Aly
Dental Sedation
Intranasal Versus Nebulized Midazolam in Behaviuor Modification of Preschool Children Undergoing Dental Treatment
The aim of the current study is to compare the effect of intranasal versus nebulized route of administration of midazolam as moderate sedative agents in preschoolers undergoing dental treatment.
- Trial name
- NCT05883150
- Testing
- Nebulized Midazolam, Intranasal Midazolam
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Nourhan M.Aly