Clinical trials: Dental Malocclusion
Malocclusion, Narrow Maxilla
Clear Orthodontic Expander Versus Hyrax
This study will be conducted to evaluate the effectiveness of a clear expander fabricated from 2-mm biocompatible polyethylene terephthalate glycol (PETG) thermoforming material integrated with an expansion screw in achieving…
- Trial name
- COE-Hyarx (NCT07362160)
- Testing
- New clear expander, Hyrax expander
- Where
- Iraq
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Malocclusion, Orthodontic Anchorage Procedures
Evaluation of the Accuracy of Palatal Orthodontic Miniscrew Placement.
This randomized clinical trial has the objective of comparing the accuracy of palatal paramedian miniscrew placement using static computer-assisted surgery (s-CAS) and dynamic computer-assisted surgery (d-CAS).
- Conditions
- Malocclusion, Orthodontic Anchorage Procedures, Orthodontics
- Trial name
- NCT07378618
- Testing
- Computer-guided Miniscrew insertion
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Injury of Trigeminal Nerve, Surgery
Sensory Retraining Facilitates Sensory Recovery After Mandibular Nerve Injury
The purpose of this study is to determine whether sensory retraining exercise could improve lip numbness caused by bilateral sagittal split of mandible.
- Conditions
- Injury of Trigeminal Nerve, Surgery, Mandibular Prognathism
- Trial name
- NCT01586598
- Testing
- sensory retraining protocol
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Chang Gung Memorial Hospital
Class II Malocclusion
Conventional Versus 3D Printed Twin Block Appliances in Growth Modification of Class II Malocclusion
The present study was conducted to evaluate the outcomes of conventionl versus 3D printed twin block appliances in growth modification of class II malocclusion (comparative clinical study) in both groups.
- Trial name
- RCT (NCT07792525)
- Testing
- Twin Block
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Anterior Open Bite
Molar Intrusion in Open Bite Treatment
This experimental study will evaluate the effect of different methods for the molar intrusion (compared with the control group) in adolescent and adult patients with open bite malocclusion.
- Trial name
- NCT02865213
- Testing
- OBA, Miniplates, Miniscrews
- Where
- Syria
- Volunteers
- 45 people
- Sponsor
- Damascus University
Dental Crowding, Malocclusion, Angle Class I
The Reliability and Validity of Little's Irregularity Index Assessment
The primary aim of the current study was to estimate the validity, reliability, and repeatability of LII measurements
- Trial name
- LII (NCT07745855)
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Al-Azhar University
Deep Bite Malocclusion
Bonded Bite Turbos Were Bonded to Palatal Surfaces of Maxillary Incisors for Sixty Patients With Anterior Deep Overbite to Check Acceptance Rate of Patients to These Bite Turbos.
Background: Bonded composite bite turbos are an efficient tool in the treatment of deep bite malocclusion. Patient satisfaction with orthodontic appliances has been correlated with treatment success.
- Trial name
- ABT-SAT (NCT07143916)
- Testing
- bonded anterior bite turbos
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Class II Malocclusion, Division 1
Pain, Discomfort, and Acceptance During Using Electrical Stimulation to Accelerate Orthodontic Teeth Movement
Forty patients with class II division 1 malocclusion who will require extraction of the upper first premolars as a part of the orthodontic treatment plan will be invited to participate in the study.
- Trial name
- NCT05920525
- Testing
- Electrical stimulation, Traditional retraction of the front upper teeth
- Where
- Syria
- Volunteers
- 40 people
- Sponsor
- Damascus University
Crossbite (Posterior), Expansion of Maxillary Arch
Comparison of Maxillary Dental Expansion Using Smartee Clear Aligner With and Without S11 Expander: A Randomized Clinical Trial
To compare the effects of Smartee S11 expander with conventional clear aligner expansion using cone beam computed tomography (CBCT).
- Conditions
- Crossbite (Posterior), Expansion of Maxillary Arch, Clear Aligner Appliance
- Trial name
- RCT expansion (NCT07533682)
- Testing
- maxillary expander with transpalatal strap S11, conventional expantion
- Where
- Saudi Arabia
- Volunteers
- 30 people
- Sponsor
- Aisha Ali Qahtani
Overbite (Excessive) Deep
Orthodontic Approaches to Correct Deep Bite in Mixed Dentition Patients
A deep bite is a bite where the upper front teeth cover almost all, if not all the lower front teeth. Currently there is no clarity which of the available treatment approaches is better when these patients still have some baby…
- Trial name
- NCT03641196
- Testing
- Fixed appliance, Composite bite plane
- Where
- Canada
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Malocclusion of Anterior Teeth
Clinical Evaluation of Zirconium Dioxide Nano-Coated Arch Wires
"This clinical trial aims to evaluate the clinical performance and efficiency of zirconium dioxide nano-coated orthodontic archwires compared to conventional archwires.
- Trial name
- NCT07813117
- Testing
- Zirconium dioxide nano-coated archwire, Conventional orthodontic archwire
- Volunteers
- 20 people
- Sponsor
- Al-Azhar University
Class II Malocclusion, Class II Malocclusion, Division 1
Comparison of Early Interceptive Orthodontic Appliances (Traditional and Novel) and Later Fixed Appliance Treatment in Class II Malocclusion.
Background Approximately 15% of children have a Class II malocclusion, where the maxilla is positioned anterior to the mandible, and around 90% of these children also present with an increased overjet.
- Conditions
- Class II Malocclusion, Class II Malocclusion, Division 1, Overjet
- Trial name
- MACTWin (NCT07404696)
- Testing
- Head gear activator, Twin Block, Invisalign mandibular advancement
- Where
- 3 sites in Sweden
- Volunteers
- 144 people
- Sponsor
- Vastra Gotaland Region
Class II Malocclusion, Class III Malocclusion
Canine Retraction With Temporary Anchorage Devices
Various malocclusions require the extraction of the first premolars and retraction of the canines with the need for maximum anchorage.
- Conditions
- Class II Malocclusion, Class III Malocclusion, Crowding, Tooth, Bimaxillary Protrusion
- Trial name
- NCT04887974
- Testing
- canine retraction
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Future University in Egypt
Class II Division 1 Malocclusion
Distalization Using Infrazygomatic Crest Miniscrews and Zygomatic Miniplates: A Randomized Clinical Trial
The main objective of this study is to quantify the distal movement of maxillary central incisors and molars achieved with infrazygomatic miniscrews in comparison with zygomatic miniplate anchorage.
- Trial name
- NCT04191070
- Testing
- infrazygomatic miniscrew, zygomatic miniplate
- Where
- India
- Volunteers
- 42 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Class II Malocclusion
Evaluation of Maxillary Molar Distalization With Two Bone Supported Protocols Using Cone Beam Computed Tomography
The goal of this clinical trial is to to evaluate and compare the skeletal and dental changes of bone supported Fast Back and bone supported modified Leaf Spring Self-Activated Expander in bilateral distalization of maxillary…
- Trial name
- NCT06308640
- Testing
- Fast Back Rapid Distalizer, Modified Leaf Spring Self-Activated Expander
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tanta University
Malocclusion, Angle Class II, Division 1
Comparison Between Two Methods in the Acceleration of the Retraction of Upper Canines
Patients at the Orthodontic Department of University of Damascus Dental School will be examined and subjects who meet the inclusion criteria will be included.
- Trial name
- NCT03659188
- Testing
- Cortico-alveolar perforations, Traditional Corticotomy
- Where
- Syria
- Volunteers
- 51 people
- Sponsor
- Damascus University
Malocclusion
OrthoPulse 2.0 and 2.1 Feasibility Evaluation
OrthoPulse is a device that uses near-infrared light therapy in order to decrease orthodontic treatment time. The aim of this study is to evaluate OrthoPulse products modified with extended arrays, OrthoPulse 2.0 and OrthoPulse…
- Trial name
- BX13 (NCT03683017)
- Testing
- OrthoPulse 2.0, OrthoPulse 2.1, Invisalign 3.5 Day Wear
- Where
- 7 sites in United States, Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Biolux Research Holdings, Inc.
Malocclusion, Tooth Movement
Additional Palatal Force in Maxillary Canine Distalization
In orthodontic treatment involving extraction of the maxillary first premolars, the canine is distalized into the extraction space using sliding mechanics.
- Trial name
- NCT07862790
- Testing
- Combined buccal and palatal distalizing force, Buccal distalizing force
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people
- Sponsor
- Atlas University
Malocclusion, Angle Class I, Crowding
The Role of Low Level Laser Therapy in Acceleration of Teeth Alignment in Lingual Orthodontic Patients
We will treat patients with class I malocclusion who have moderate crowding (4-6 mm) according to Little's irregularity index and asses the efficacy of low level laser therapy in accelerating orthodontic tooth movement .
- Trial name
- NCT03646942
- Testing
- low level laser therapy, Lingual Orthodontics
- Where
- Syria
- Volunteers
- 36 people
- Sponsor
- Damascus University
Orthodontic Pain (D013850), Malocclusion
Comparison of Three Orthodontic Separators for Pain, Plaque, and Tooth Separation
Orthodontic separators are small devices placed between teeth before fitting braces to create space for bands. This procedure may cause pain, discomfort, and changes in oral hygiene, which can affect plaque buildup and daily…
- Conditions
- Orthodontic Pain (D013850), Malocclusion, Orthodontic Treatment
- Trial name
- SEP-ORTHO (NCT07532044)
- Testing
- Elastomeric Separator, Kesling Separator, Tie wire separator
- Where
- Pakistan
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Islamabad Medical and Dental College