Clinical trials: Dental Health
Healthy
The Effect of a Postbiotic on Oral Health in Healthy Adults
The goal of this randomised, placebo-controlled trial is to determine the effect of a chewable postbiotic tablet on the oral health of male and female healthy adults under conditions of short term oral-neglect (a short, temporary…
- Trial name
- LOOFAH2 (NCT07830862)
- Testing
- Postbiotic
- Where
- Canada
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- The Archer-Daniels-Midland Company
PERIODONTAL DISEASE
Dental Engagement Study Behavior Modification
This is a pilot study to determine whether knowledge gained by an individual of genetic risk for severe periodontitis changes the patient's health behavior as measured by an increased frequency of their preventive dental office…
- Trial name
- NCT02749318
- Testing
- IL-1 genetic test for risk of severe periodontitis
- Sponsor
- Interleukin Genetics, Inc.
Dental Plaque, Behavior
The Impact of a 21day School Brushing Intervention on the Knowledge, Behaviour and Oral Health of School Children
In this study we aim to study the effectiveness of a specially designed 21 day Brush Day and Night programme for school children aged 6-9 which aims to establish the habit of twice a day toothbrushing for oral health.
- Conditions
- Dental Plaque, Behavior, Behavior, Health
- Trial name
- NCT04001296
- Testing
- 21 day Brush Day and Night school programme
- Where
- 2 sites in Indonesia, Nigeria
- Volunteers
- 2,020 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Dentin Sensitivity
Real-World Study of a Calcium Sodium Phosphosilicate Anti-Sensitivity Toothpaste for Dentin Hypersensitivity Relief
The aim of this study is to evaluate the impact of a commercially available desensitizing dentifrice containing 5 percent (%) Calcium sodium phosphosilicate (CSPS) on oral health related quality of life (OHrQoL) in a DH (Dentin…
- Trial name
- NCT07300540
- Testing
- Calcium sodium phosphosilicate (CSPS) Toothpaste
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- HALEON
Tooth Discoloration, Periodontal Diseases
Evaluating the Efficacy of a Gum Health Formulation on Teeth Whitening in Patients With Gingivitis and Periodontitis
The purpose of this study is to evaluate the efficacy of a novel gum health formulation, when used in an intra-oral device or on a toothbrush, for teeth whitening and clinical improvements in periodontal diseases.
- Trial name
- NCT02906982
- Testing
- Gum health formulation in intra-oral device, Gum health formulation on toothbrush
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Glo Science, Inc.
Oral Health
Evaluation of a Daily Oral Care Lozenge on Oral Health and Quality of Life in Older Adults
The assessment of a daily oral care lozenge (PTx800) will be compared to a placebo control in a cohort of older adults who visit adult senior centers and who also have mild to moderate gingivitis.
- Trial name
- NCT03693027
- Testing
- PTx800 lozenges
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Primal Therapies Inc.
Gingivitis, Dental Plaque Accumulation
6-month Clinical Investigation Assessing the Efficacy of an Antimicrobial Mouthrinse in Reducing Established Plaque and Improving Gum Health
The goal of this clinical trial is to evaluate the clinical efficacy of an antimicrobial mouthrinse, with a particular focus on its effect on established plaque and the improvement of gum health.
- Trial name
- NCT07414173
- Testing
- Test Mouthrinse, Control Mouthrinse
- Where
- Germany
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dental Plaque
Dental Plaque Removal Ability of Prototype Power Toothbrush Versus a Manual Toothbrush in Healthy Participants
The aim of this study is to evaluate the ability of a prototype power toothbrush (PTB) versus a manual toothbrush in healthy, right-handed manual toothbrush (MTB) participants with no signs of periodontal disease or excessive…
- Trial name
- NCT03809910
- Testing
- Reference MTB, Reference PTB, Prototype PTB (Gum line mode)
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Gingivitis
Powered Toothbrush Versus Manual Toothbrush on Plaque and Gingivitis After a Six-Week Period of Home Use
The goal of this clinical trial is to learn if powered toothbrushing is more effective than manual toothbrushing in removing dental plaque. It will also learn about the safety of power toothbrushing.
- Trial name
- NCT07691814
- Testing
- power toothbrush, manual toothbrush
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Oral Health Literacy
Evaluation of the Know Your OQ™ Oral Health Literacy Tool in an Indian Population
This was a research study to evaluate the effectiveness of the questionnaire "Know Your OQ™" (Know Your Oral Health Quotient™) in changing people's level of knowledge about oral health in India and to evaluate the readability…
- Trial name
- KYOQIN (NCT06534112)
- Where
- India
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dentin Sensitivity
Impact of Long Term Management of Dentine Hypersensitivity (DH) With a Daily Use Anti-sensitivity Toothpaste on the Quality of Life Related to Oral Health
This multicentre, non-comparative design study will monitor the impact of long term management of DH with daily use of a sensitivity toothpaste on the quality of life of a population of sensitivity sufferers.
- Trial name
- NCT02752958
- Testing
- stannous fluoride
- Where
- 2 sites in United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Gingivitis, Dental Plaque
A Meta-analysis Comparing Toothbrushes on Plaque Removal and Gingival Health
The aim of this analysis was to compare gingivitis- and plaque-reduction efficacy from randomized controlled trials (RCTs) up to six months long evaluating oscillating-rotating, sonic, and manual toothbrushes
- Trial name
- NCT05594004
- Testing
- Oscillating-rotating electric toothbrush, Sonic electric toothbrush, Manual toothbrush
- Where
- United States
- Volunteers
- 2,929 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Stabilization of a Full Lower Denture, Edentulism in Lower Jaw
Clinical Evaluation of the Mandibular Mini-Implant Overdenture
Stabilization of existing full lower dentures by means of mini-dental implants (MDI). To test whether 4 mini-implants placed at the front of the lower jaw can stabilize an immediately-modified existing lower denture.
- Conditions
- Stabilization of a Full Lower Denture, Edentulism in Lower Jaw, Lower Denture Made Within Last Few Years
- Trial name
- NCT01064843
- Testing
- Imtec MDI
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Solventum US LLC
Gingivitis
Efficacy of SALI-10 Oral Probiotics in Experimental Gingivitis
Gingivitis is among the most prevalent oral diseases worldwide, affecting an estimated 50-90% of adults. It is a reversible condition primarily caused by microbial plaque accumulation on teeth and gingival surfaces, which…
- Trial name
- NCT07256743
- Testing
- SALI-10 lozenge
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ostia Sciences
Gingiviits
Comparion of Effects of Two Different Power Toothbrushes on Plaque and Gum Health
The goal of this clinical trial is to learn if powered toothbrushing with a side-to-side motion is more effective than powered toothbrushing with oscillating-rotation motion in removing dental plaque.
- Trial name
- NCT07813546
- Testing
- oscillating-rotating powered toothbrush, side-to-side powered toothbrush
- Where
- United States
- Volunteers
- 295 people, healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Delivery Systems, Oral Health
Determining the Viability a Lozenge Dosage for Probiotics
Gingivitis is an oral disease condition affecting 50% to 90% of adults globally. Gingivitis is a reversible inflammatory condition caused by the accumulation of dental plaque and the associated disruption of the host-microbial…
- Trial name
- NCT06819761
- Testing
- Salivarius SALI-10
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Ostia Sciences
Oral Health
The Effects of an Oral Probiotic Intervention With or Without a Novel ADP-1 Toothpaste
Randomized double-blind, placebo-controlled trial on the effects of an oral probiotic intervention with or without a novel ADP-1 toothpaste Objective Determine the safety and effectiveness of oral probiotic intervention with or…
- Trial name
- NCT05330793
- Testing
- Oral probiotic
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- USANA Health Sciences
Parodontitis
Evaluation of the Efficacy of STERIFY GEL in the Treatment of Periodontitis Following Scaling and Root Planing
The purpose of this clinical study is to evaluate the safety and efficacy of treating periodontal disease with the STERIFY GEL medical device in combination with SRP procedure, in terms of periodontal pocket healing.
- Trial name
- SFYCT (NCT05975177)
- Testing
- Sterify Gel, Scaling and root planing
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- Sterify S.r.l.
Gingivitis
A Phase 3 Clinical Study Investigating the Gingivitis Efficacy of a Test Dentifrice Containing Stannous Fluoride
The purpose of this study is to evaluate and compare the gingival health of a test dentifrice (0.454% weight by weight [w/w] stannous fluoride) to a negative control dentifrice by comparing modified gingival index, bleeding index…
- Trial name
- NCT04123665
- Testing
- Stannous fluoride, Sodium monofluorophosphate
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dental Health
Oral Tissue Tolerance of a Mouthrinse
This study is 8 weeks long. People participating in this study will be asked to brush their teeth two times a day. Some people will get a mouthwash. People with a mouthwash will rinse two times a day after brushing their teeth.
- Trial name
- NCT01009554
- Testing
- Potassium Oxylate Mouthwash, Sodium Fluoride Dentifrice
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide