Clinical trials: Dental Diseases
Necrotic Pulp, Apical Periodontitis
Regenerative Endodontic Treatment of Mature Necrotic Teeth With Apical Periodontitis
The aim of this prospective, randomized, controlled double-blind study is to evaluate the effectiveness of biodentine compared with MTA used as pulp space barrier on discoloration of teeth after regenerative based non-obturation…
- Trial name
- NCT04018456
- Testing
- Biodentine, White MTA
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Cairo University
Blood Coagulation Disorders
Dental Extractions in Patients Under Dual Antiplatelet Therapy
The purpose of this study is to compare two hemostatic agents in patients under dual antiplatelet therapy using the intraoral bleeding time after dental extractions.
- Trial name
- DUALex (NCT02918045)
- Testing
- HemCon Dental Dressing, Oxidized Cellulose Gauze
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo General Hospital
Dental Anxiety in Children, Dental Pain
Kaleidoscope Compared to Tell-Show-Do for Reducing Children Pain and Anxiety During Pulp Therapy
The goal of this clinical trial is to investigate if Kaleidoscope glasses help children feel less pain and worry during dental work. It will also explore if these glasses help children feel more comfortable with the dentist.
- Trial name
- NCT07595731
- Testing
- behavior management using Kaleidoscope glasses (SOL, country of origin: China)., behavior management using the Tell-Show-Do technique and Kaleidoscope glasses (SOL, country of origin: China)., behavior management using the Tell-Show-Do technique.
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Cairo University
Caries
A Strategy to Prevent the Recurrence of Dental Disease in Children Receiving Dental Treatment With General Anesthesia
The purpose of this study is to evaluate the effectiveness of a preventive strategy in increasing return to follow up and recall appointments.
- Trial name
- NCT05212142
- Testing
- verbal education, verbal education, visual aids, and motivational interviewing
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Virginia Commonwealth University
Liver Cirrhosis, Periapical Lesions
Oral Health Status in Patients With Cirrhosis and Effect of Dental Treatment on MELD Score of Cirrhosis Patients
It has been found that there is an association between prevalence of odontogenic infection and systemic diseases.Cirrhosis has also been associated with poor oral health status.Treating those patients accordingly can help in…
- Trial name
- NCT04399512
- Testing
- Nonsurgical root canal treatment
- Where
- India
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Dental Implant Failed, Teeth Absent
Gelatin Sponge VS PTFE Membrane for Socket Sealing After Immediate Implant Placement
Digital panoramas will be made to assess the implant sites. The included patients are assigned to their respective groups randomly.
- Conditions
- Dental Implant Failed, Teeth Absent, Soft Tissue Injuries
- Trial name
- NCT05982353
- Testing
- PTFE application, Gelatin sponge
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain, Postoperative
Safety and Efficacy of Intranasal Ketamine for the Treatment of Postoperative Dental Pain
Once patients' postoperative pain intensity reaches a moderate-to-severe level, they are randomized to receive intranasal ketamine or placebo.
- Trial name
- NCT00488787
- Testing
- intranasal ketamine
- Volunteers
- 40 people
- Sponsor
- Javelin Pharmaceuticals
Missing Teeth
Evaluation of the Abutment Type Following Oral Implants in Terms of the Surrounding Bone Height
Compare two different types of abutments (molded abutments and computer-designed 3D printed abutments) in terms of the amount of bone loss, and depth of periodontal pockets around the implant during different periods.
- Trial name
- NCT05350293
- Testing
- Molded abutment, 3D printed abutment
- Where
- Syria
- Volunteers
- 32 people
- Sponsor
- Damascus University
Dental Caries
Evaluation of the Salivary-free Amino Acids Levels (Glycine , Proline , Lysine , and Alanine ) With Caries Activity
This study will be aimed to investigated the correlation between levels of salivary amino acids (glycine , proline , lysine , alanine ) in the saliva of healthy children with and without active carious lesions and to estimate the…
- Trial name
- NCT06953557
- Testing
- To compare the effect of salivary glycine , proline , lysine and alanine concentration between participants with high caries activity and participants with negative caries activity
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Molar Incisor Hypomineralisation
Hydroxyapatite vs Fluoride Toothpaste for MIH Remineralization
Molar Incisor Hypomineralization (MIH) is a common developmental enamel defect affecting children, particularly in Dubai, where it contributes to hypersensitivity, esthetic concerns, plaque accumulation, and increased caries…
- Trial name
- MIH-CARE (NCT07177053)
- Testing
- non fluoridated hydroxyapatite tooth paste (KAREX KINDER tooth paste), fluoridated toothpaste (Colgate Total PROTECTION ACTIVE)
- Volunteers
- 160 people
- Sponsor
- Dubai Health
Dental Plaque
Oral Imaging for Porphyrin Biomarkers
The purpose of this study was to use the principle of fluorescence to identify oral diseases not readily visible to the naked eye.
- Trial name
- NCT03379337
- Testing
- Dental imaging
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Massachusetts Institute of Technology
Peri-Implantitis, Mucositis
Exploring the Relationship Among Dental Caries, Nutritional Habits and Peri-implantitis
Aim: A study was made of the prevalence, co-occurrence and association among caries, nutritional habits and peri-implant disease, with an analysis of the influence of other patient and implant factors upon peri-implant disease.
- Conditions
- Peri-Implantitis, Mucositis, Caries,Dental, Nutrition
- Trial name
- NCT04439877
- Testing
- Peri-implant disease diagnosis
- Where
- Spain
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Dental Caries
Effect of Sour Cherry Anthocyanins on Healthy Human Saliva
The experiment is based on earlier research where it was proven that chewing gum usage with anthocyanin rich sour cherry extract significantly reduces the amount of human salivary alpha-amylase in unstimulated saliva samples and…
- Trial name
- NCT05406011
- Testing
- Pelleted sour cherry (anthocyanin) containing chewing gum usage., Pelleted chewing gum for stimulated saliva sampling., Scaling
- Where
- Hungary
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Debrecen
Endodontic Disease, Endodontic Re-treatment Failure
Guided Versus Conventional Periapical Endodontic Surgery
This study is to compare the clinical and radiographic outcomes after guided periapical endodontic surgery versus conventional endodontic surgery.
- Trial name
- NCT04133181
- Testing
- 3D guide, Mock guide
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, Dental Fillings
SEM Evaluation of the Quantity of microRepair® on Resin Composite Surfaces: an in Vivo Randomized Clinical Trial.
The aim of this study is to evaluate the quantity of Biorepair Total Protection toothpaste on composite surfaces inside oral cavity.
- Trial name
- NCT04808557
- Testing
- Biorepair Total Protection, Sensodyne Repair & Protect
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Alveolar Bone Loss, Bone Resorption
Alveolar Management Following Teeth Extraction
Investigation of the volume stability of the alveolar ridge, the bone structure and soft tissue appearance at a delayed dental implantation using two bone substitute materials (1. Human-Spongiosa, gefriergetrocknet, CHB; 2.
- Trial name
- NCT03089619
- Testing
- Human-Spongiosa, collacone®
- Where
- Germany
- Volunteers
- 21 people
- Sponsor
- University Medicine Greifswald
Bone Loss, Inflammation
Healing of Bone/Soft Tissue to Different Abutment Biomaterials and the Impact on Marginal Bone Loss
In patients that require a dental implant, does zirconia compared to titanium, or cad-cam acrylic abutments, provide less inflammation, marginal bone loss or infection during the osseointegration period ?
- Trial name
- NCT01961635
- Testing
- dental implants, Zirconia abutments, Titanium Abutments
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Implantology Institute
Dental Caries
Predicting Caries Risk in Underserved Toddlers in Primary Healthcare Settings
The study aims to develop a questionnaire that can be used to help uncover a child's risk of developing dental caries (also known as tooth decay or a cavity).
- Trial name
- NCT01707797
- Where
- 3 sites in United States
- Volunteers
- 1,326 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Dental Caries
Occlusal ART Restorations in Primary Molars Using 3 Different GIC
The aim of this study is to evaluate the survival rate and the cost-effectiveness of occlusal-ART restorations using three GIC brands (Fuji IX, GC Europe; Maxxion R, FGM; Vitro Molar, DFL) in primary molars.
- Trial name
- NCT02377297
- Testing
- Restoration with Fuji IX, Restoration with Vitro Molar, Restoration with Maxxion R
- Where
- Brazil
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dental Implant Failure, Periodontal Bone Loss
A Retrospective Analysis of Failures of Oral Implants
The purpose of this retrospective study is to investigate and identify factors associated with the failure of dental implants within the population rehabilitated with dental implants at the Folktandvården Specialistklinik in…
- Trial name
- NCT02369562
- Testing
- Evaluation of the failure rate of dental implants
- Where
- Sweden
- Volunteers
- 2,670 people, healthy volunteers welcome
- Sponsor
- Malmö University
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