Clinical trials: Dental Caries
Dental Caries, Class II Dental Caries
Class II Restorations With High-Filled Flowable Composites
In the study, Class II restorations will be performed with G-aenial Universal Injectable (GC/ Tokyo, Japan), Grandio Flow (VOCO/ Germany), and Clearfil Majesty Flow (Kuraray/ Japan) composites will evaluated.
- Trial name
- NCT06346795
- Testing
- High-filling flowable dental composite
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Periodontal Disease, Periapical Disease
Periodontal and Periapical Inflammation and Pregnancy
This is a retrospective chart review of patient records at the University of Mississippi Medical Center. We are not actively recruiting patients for this study.
- Conditions
- Periodontal Disease, Periapical Disease, Pregnancy, Diabetes
- Trial name
- NCT00490165
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Roger Johnson
Incipient Interproximal Caries
Can SAP P11-4 Affect The Appearance of Interproximal Cavities on an X-ray in a Military Population
The primary objective of the protocol is to learn about how SAP P 11-4 (produced commercially as Curodont products) can be used in a military population to treat incipient dental caries, or developing cavities that are still…
- Trial name
- NCT07829328
- Testing
- 0.05% Sodium Fluoride with Self-Assembling Peptides
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Tripler Army Medical Center
Caries, Dental
Prevention of Adult Caries Study (PACS)
Adult tooth decay is an infectious disease that afflicts the majority of Americans aged 55 and older and is the most common chronic disease at midlife with an ever growing economic toll.
- Trial name
- NCT00357877
- Testing
- 10% w/v chlorhexidine acetate coating FDA IND #45466
- Where
- 4 sites in United States
- Volunteers
- 983 people
- Sponsor
- Tufts University
Obesity, Dental Caries
Nutrition Knowledge for Spanish-speaking Parents
Providing child nutrition information is a major goal of every pediatric well-child visit. Unfortunately, due to a wide array of issues, doing this effectively during clinic visits is challenging and insufficient.
- Trial name
- NCT01296945
- Testing
- Kiosk, paper, Kiosk PLUS paper
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Dental Caries, White Spot Lesions
QLF and Digital Imaging for Caries Activity Assessment After Orthodontic Treatment
This prospective longitudinal observational study aims to evaluate the diagnostic performance and agreement of Smartphone photography, intraoral 3D imaging, Quantitative Light-Induced Fluorescence Digital (QLF-D), and ICDAS…
- Conditions
- Dental Caries, White Spot Lesions, Caries Lesion Activity, Post-Orthodontic Enamel Demineralization
- Trial name
- NCT07608471
- Volunteers
- 30 people
- Sponsor
- Universidad El Bosque, Bogotá
Caries Active, Caries Root
Surface Caries Feature Study
Dental caries (dental cavity) is very common and can impact oral health and oral health-related quality of life. Dental caries is when the tooth surfaces break down, and if left untreated, can cause tooth pain.
- Conditions
- Caries Active, Caries Root, Caries,Dental, Caries; Initial
- Trial name
- NCT07048444
- Testing
- N/A as observational study
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- 3Shape A/S
Pregnancy Related, Dental Caries
The Effects of Pregnancy on Oral Health
The aim of this study was to evaluate the effects of pregnancy on salivary pH, flow rate, caries experience and periodontal status.
- Conditions
- Pregnancy Related, Dental Caries, Periodontal Diseases, Saliva Altered
- Trial name
- NCT06343337
- Testing
- Evaluation of DMFT index, CPI scores, salivary pH and flow rate in pregnant and non-pregnant woman
- Where
- Turkey (Türkiye)
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Muğla Sıtkı Koçman University
Dental Caries, Dental Caries in Children
Atraumatic Versus Silver-Modified Atraumatic Restorative Treatment in Primary Molars
The goal of this clinical trial is to evaluate and compare the short-term effectiveness of two minimally invasive treatments-Atraumatic Restorative Treatment (ART) and Silver-Modified Atraumatic Restorative Treatment (SMART)-in…
- Trial name
- NCT07023939
- Testing
- ART: Atraumatic restorative treatment, SMART: Silver-Modified Atraumatic Restorative Treatment
- Where
- Lebanon
- Volunteers
- 34 people
- Sponsor
- Beirut Arab University
Decayed Teeth
Vital and Non-vital Posterior Teeth Restored With Onlays and Single Crowns Using Three Different Restorative Materials.
The objective of this study is to assess the survival rate and the biological and technical outcomes of onlays and single crowns made out of different restorative materials on vital and non-vital teeth.
- Trial name
- NCT07259265
- Testing
- Crown preparation, Onlay preparation
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Dr. med. dent. Malin Strasding
Plaque, Patient Satisfaction
Recycling of Three Pressable Ceramics With Different Weight Percentage
Introduction: Green dentistry, is high-technology approach that reduces the environmental impact of dental practices, improper disposal of dental materials wastes results in environmental hazards.
- Conditions
- Plaque, Patient Satisfaction, Caries, Cervical, Post Operative Pain
- Trial name
- NCT06575803
- Testing
- clinical measurements and evaluation
- Where
- 2 sites in Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
Dental Caries, Tooth Fractures
Comparison of Conventional and CAD/CAM Dental Restorations
Dental restorations (crowns, inlays or onlays) can be made conventionally or by CAD/CAM. The current literature is weak and does not separate the medical results of these two techniques.
- Conditions
- Dental Caries, Tooth Fractures, Tooth Resorption
- Trial name
- EVACFAOD (NCT02494427)
- Testing
- CAD/CAM manufactured fixed unitary dental prostheses, Conventionally manufactured unitary dental prostheses
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Black Stain Dental, Dental Black Stain, Black Stain*, Black Stains, Tooth Stains
Assessment of Salivary Bacterial Level and Dental Caries Experience in a Group of Egyptian Children With Black Stained Teeth
Black stains (BS) are type of extrinsic discoloration of the tooth. It's characterized as dark lines or an incomplete coalescence of dark dots found mostly on cervical third of the crown.
- Trial name
- NCT03563469
- Testing
- Salivary bacterial and pH level
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Cairo University
Caries, Caries,Dental
Extraction of the Compromised First Permanent Molars
Compromised first permanent molars (FPM), whether diagnosed with severe molar incisor hypomineralization (MIH), irreversible pulpities, or necrosis, require frequent re-treatment consequently entering the restorative cycle, which…
- Trial name
- FPM (NCT06231823)
- Testing
- Extraction
- Where
- Egypt
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
White Spot Lesion of Tooth, Long Term Adverse Effects
Comparison of Efficacy Of Probiotic Toothpaste and Chlorhexidine Mouthwash To Reduce S.Mutans
Orthodontic appliance causes increase in plaque accumulation, especially around brackets, wires and attachments. Advances in orthodontics in recent time have led to improved quality of appliance and treatment procedures…
- Conditions
- White Spot Lesion of Tooth, Long Term Adverse Effects, Caries, Dental, Orthodontic Appliance Complication
- Trial name
- NCT03004196
- Testing
- Probiotic Toothpaste, Dr. Reddy's Clohex, Control Group
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Peoples University, Bhanpur, Bhopal
Dental Caries (Diagnosis), Dental Plaque (Diagnosis)
Intra Oral Scan and CBCT Aided Diagnosis of Dental Plaque and Caries
In this prospective controlled trial, patients will be enrolled at the University Hospital Ghent. Inclusion criteria are: age between 18 and 70 years old, presence of 20 or more teeth, and have a minimum one carious tooth…
- Trial name
- NCT06945354
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- University Ghent
Early Childhood Caries, Dental Caries in Children
Treatment of Early Childhood Caries Using Silver Diammine Fluoride and Sodium Fluoride Tricalciumphosphate and the Effects on Oral Health Related Quality of Life
There is still a need for the assessment of different minimal intervention strategies and treatments focusing on the prevention and arrest of carious lesions of primary molars The evidence-based clinical practice guideline on…
- Conditions
- Early Childhood Caries, Dental Caries in Children, Dental Caries Extending Into Dentin, Dental Caries
- Trial name
- NCT05772039
- Testing
- Topical application of 38% Silver Diammine Fluoride Solution, Topical application of 5% Sodium Fluoride with functional Tricalcium phosphate Varnish
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- Universiti Sains Malaysia
White Spot Lesions
P11-4 and Fluoride Varnish for Remineralization of Post-orthodontic Lesions
This clinical study aims to compare the remineralizing effects of self-assembling peptide P11-4 (SAP11-4) with fluoride varnish in the treatment of post-orthodontic non-cavitated carious lesions (NCLs).
- Trial name
- NCT06749977
- Testing
- Remineralization with SAP11-4, Remineralization with sodium fluoride varnish
- Where
- Bulgaria
- Volunteers
- 45 people
- Sponsor
- Medical University of Sofia
Primary Teeth, Dental Caries
Assessment of Stainless Stain Crowns Placed Using the Hall Technique and Traditional Technique
The purpose of this study is to evaluate and compare the clinical performance of Stainless Stain Crowns Placed Using the Hall Technique and Traditional Technique
- Conditions
- Primary Teeth, Dental Caries, Dentin, Carious
- Trial name
- NCT03433157
- Testing
- Hall technique, Traditional technique
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Deep Caries, Dental Caries
Evaluation of Bioactive Giomer Material Versus Nanohybrid Resin Composite in Deep Marginal Elevation
This study will be conducted to evaluate the clinical, radiographic and periodontal performance of bioactive Giomer compared to nanohybrid resin composite restoration in deep subgingival proximal cavities extending below the CEJ…
- Trial name
- NCT06497231
- Testing
- Beautifil II LS, Nanohybrid resin composite material
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
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