Clinical trials: Dental
Severe Atrophy of the Edentulous Maxilla
"Tunnel" Flap vs Trapezoidal Flap for Lateral Sinus Lift
The goal of this clinical trial is to evaluate the efficacy of the lateral sinus lift procedure using the tunnel technique flap in comparison to the traditional lateral sinus lift in partially or totally edentulous patients with…
- Trial name
- NCT06105489
- Testing
- Lateral Sinus Lift using tunnel flap technique, Lateral Sinus Lift using crestal incision flap
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- Studio Dentistico Associato Sivolella
Missing Teeth
Dental Implant Treatment for Two Adjacent Teeth in the Maxillary Aesthetic Region: an Evaluation After 10 Years
Background Replacement of two missing adjacent teeth is considered a difficult treatment in implant dentistry and even more challenging if located in the anterior region due to aesthetic demands.
- Trial name
- 2implants (NCT05359549)
- Testing
- Two endosseous dental implants (NobelReplace Groovy®) were placed 10 years ago
- Where
- Netherlands
- Volunteers
- 25 people
- Sponsor
- University Medical Center Groningen
Dental Implant, Computer-assisted
Accuracy of Static Computer-assisted Implant Surgery in Distal Free-end Scenarios
Technological advances have influenced the approach to implant treatment. One of the fields presently experiencing rapid development is static computer-assisted guided surgery (sCAIS), which allows transfer of the virtual implant…
- Trial name
- NCT06404385
- Testing
- Static computer-assisted guided surgery with analogic guide, Static computer-assisted guided surgery with CAD-CAM surgical guide
- Where
- Spain
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Dental Pain
A Study of ARRY-371797 in Subjects Undergoing Third Molar Extraction
This is a Phase 2 study designed to test the ability of investigational study drug ARRY-371797 to reduce pain either perioperatively or postoperatively in a third molar extraction pain model, and to further evaluate the drug's…
- Trial name
- NCT00542035
- Testing
- ARRY-371797, p38 inhibitor; oral
- Where
- 2 sites in United States
- Volunteers
- 103 people
- Sponsor
- Pfizer
Dental Implant, Computer
Accuracy of Computer- Guided Implant Surgery in Partially Edentulous Patients.
The dental implant placed freehand with a digital planing is vastly increasing. The accuracy between the planned and the placed implants still not well determined.
- Trial name
- NCT06277076
- Testing
- Computer Implant guided Surgery
- Where
- Lebanon
- Volunteers
- 13 people
- Sponsor
- Saint-Joseph University
Dental Caries of Root Surface, Surgery
Intraoral Imaging at Clinical Crown Lengthening
Crown lengthening surgery is done when a tooth needs to be fixed with a crown. Sometimes, not enough of the tooth sticks out above the gum to support a crown.
- Trial name
- NCT03064217
- Testing
- Making impression at surgery
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Edentulism
Clinical Performance Evaluation of Two Different Dental Implants
In brief, the aim of this randomized controlled trial is to evaluate the patient satisfaction and the clinical performance of two types of implants: 1) HA-coated hybrid dental implant and 2) non-coated moderately rough dental…
- Trial name
- HAHy-vs-C (NCT03845335)
- Testing
- dental implant-supported restoration
- Where
- 4 sites in Italy
- Volunteers
- 600 people
- Sponsor
- Elite Odontoiatrica
Dental Trauma
the Effect of Educational Program on Teachers' Knowledge Self-reported Practice Towards TDIs
The study aims at evaluating the effect of an oral health educational program on the knowledge and self-reported protocol of primary school teachers in Beni-Suef towards traumatic dental injuries.
- Trial name
- NCT04462744
- Testing
- educational program
- Where
- Egypt
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Inflammation, Dental Caries
Effectiveness of Toothpaste Tablets on Plaque, Gingival Health and Caries Experiences
Objectives: To evaluate the effectiveness of toothpaste tablets when compared to conventional dentifrices in removing plaque. Methods: 50 participants are randomized into two groups: Denttabs toothpaste tablets (T) and Colgate's…
- Trial name
- NCT07124533
- Testing
- Toothpaste Tablet, Conventional Toothpaste
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Dental Implant, Tooth Loss
Flap Vs Flapless Technique for Delayed Implant Placement in the Maxillary Esthetic Zone
This randomized comparative clinical trial aims to evaluate the clinical, radiographic, and esthetic outcomes of flap versus flapless techniques for delayed dental implant placement in the maxillary esthetic zone.
- Conditions
- Dental Implant, Tooth Loss, Partial Edentulism, Maxillary Tooth Loss
- Trial name
- NCT07654452
- Testing
- Flap Implant Placement, Flapless Implant Placement
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Chronic Periodontitis, Periodontal Bone Loss
Use of the xCELLigence System for Quantification of Bacterial Biofilm's Real Time Formation and Antibiotics Selection.
The aim of the study is to develop an in vitro model of growth of oral biofilms, and validate xCELLigence system for the selection of an effective antibiotic treatment for each patient.
- Conditions
- Chronic Periodontitis, Periodontal Bone Loss, Resistance Bacterial
- Trial name
- NCT03863249
- Testing
- SCALE AND ROOT PLANING, ADJUNTIVE ANTIBIOTICS, MICROBIAL SAMPLING
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- University of Valencia
Palatal Donor Site Wound Healing, Platelet Rich Fibrin
Characterizing the Effects of Platelet-Rich Fibrin (PRF) as a Palatal Wound Dressing on Quality of Life and Sleep Following Mucogingival Surgery. Study Was Conducted at the Air Force Post Graduate Dental School. All HIPPA Consents and Research Informed Consents Are Located at JBSA-Lackland.
The goal of this clinical trial (2-arm) is to determine if the application of platelet rich fibrin (PRF) to palatal donor sites influence patients quality of life, sleep efficiency, and healing following mucogingival surgery.
- Conditions
- Palatal Donor Site Wound Healing, Platelet Rich Fibrin, Sleep Quality, Pain
- Trial name
- NCT07637838
- Testing
- Platelet rich fibrin, Control Group: collagen matrices or oxidized cellulose membrane
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- 59th Medical Wing
Osteoporosis
Osteoporosis and Dental Implant
The purpose of this study is to evaluate the influence of alendronate therapy on the wound healing after dental implants in patients with osteoporosis.
- Trial name
- OPOZAHN (NCT00727493)
- Testing
- alendronate once weekly 70mg
- Where
- Germany
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Dental Caries
Sealing Manifest Occlusal Caries Lesions in the Permanent Dentition
The research project "SEAL-DK" is focusing on advantages and disadvantages of two treatment strategies: non-invasive fissure sealing and invasive restorative treatment of manifest occlusal caries lesions in permanent teeth in…
- Trial name
- SEAL-DK (NCT02573090)
- Testing
- Non-invasive resin based fissure sealing, Invasive resin based restoration
- Volunteers
- 521 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Dental Implant, Tooth Extractions
Effects of Implant Placement Depth (4 mm Versus 6 mm) on Crestal Bone Stability in Immediate Implant Placement: A Clinical Study With 1-Year Post-Restorative Results
The aim of a study was to analyze the effect of implant placement depth (4 mm versus 6 mm below the mid-facial gingival margin) on marginal bone loss (MBL) around implant and implant stability during immediate implant placement…
- Conditions
- Dental Implant, Tooth Extractions, Marginal Bone Loss Around Implants, Primary Stability of the Implants
- Trial name
- NCT07574710
- Testing
- Implants were positioned 4 mm below the mid-facial gingival margin, Implant was placed 6 mm below free gingival margin
- Where
- Lithuania
- Volunteers
- 35 people
- Sponsor
- Tomas Linkevicius
Accuracy of AI App, Accuracy of AI Assisted Surgical Guides
Accuracy of AI Assisted Surgical Guide (AISG)
The purpose of this study is to evaluate and compare the accuracy of conventional static surgical guide and AI-assisted static surgical guide in implant placement in the esthetic zone of partially edentulous maxilla , This study…
- Trial name
- AISG (NCT07711613)
- Testing
- Implant placement using Conventional static surgical guide, Implant placement using AI assisted surgical guide
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Suez Canal University
Dental Caries
Evaluation of Preventive Regimens With Different Toothpastes vs Fluoride Varnish & Toothpaste in High Caries Patients
This study will be conducted in order to determine the prevention effect of caries preventive regimen using herbal toothpaste and regimen using fluoride toothpaste versus fluoride toothpaste and fluoride varnish on the caries…
- Trial name
- NCT04436913
- Testing
- Himalaya complete care toothpaste, Signal toothpaste, Signal toothpaste and fluoride varnish
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Bone Atrophy
Efficacy in Alveolar Bone Regeneration With Autologous MSCs and Biomaterial in Comparison to Autologous Bone Grafting
A randomized controlled clinical multi center trial to assess the efficacy of a combination of autologous mesenchymal stem cells and biomaterial in jaw bone regeneration prior to dental implant placement in comparison to standard…
- Trial name
- Maxibone (NCT04297813)
- Testing
- Advanced medicinal Therapy (MSC combined with biomaterial), Autologous bone graft
- Where
- 6 sites in Denmark, France and 2 more
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Biofilm, Dental Plaque
Comparison of Biofilm Characteristics Between an in Situ Biofilm Model of Supragingival Plaque and Natural Teeth
The purpose of this study is to determine in situ the bacterial viability, thickness and bacterial diversity of a biofilm formed on different substrates in comparison to a naturally tooth-formed oral biofilm.
- Trial name
- NCT02769260
- Testing
- Toothbrushing
- Where
- Spain
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Postoperative Pain, Postsurgical Pain
Influence of Insertion Torque and Bone Type on Post-operative Pain
The objectives of this clinical study were to assess the effect of different ITs and bone types on POP levels and survival rates and to investigate the effect of different patient- and site-related factors on POP levels and…
- Conditions
- Postoperative Pain, Postsurgical Pain, Dental Implant Failed
- Trial name
- NCT06412380
- Testing
- Implant insertion
- Where
- United Arab Emirates
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of Sharjah