Clinical trials: Dementia Education
Healthy, Mild Cognitive Impairment
Does Acoustic Stimulation During Sleep Boost Slow Wave Sleep and Memory Performance?
With aging the amount of slow wave sleep decreases drastically and this disruption is markedly exaggerated in older adults suffering from mild cognitive impairment and Alzheimer's disease.
- Conditions
- Healthy, Mild Cognitive Impairment, Alzheimer Disease
- Trial name
- NCT04277104
- Testing
- Closed loop acoustic stimulation
- Where
- Switzerland
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Bern
Dementia
A Novel Machine Learning Algorithm to Predict the Lewy Body Dementias
Parkinson's disease dementia (PDD) and Dementia with lewy bodies (DLB) are dementia syndromes that overlap in many clinical features, making their diagnosis difficult in clinical practice, particularly in advanced stages.
- Trial name
- MLDLB (NCT04448340)
- Testing
- machine learning model
- Where
- Greece
- Volunteers
- 200 people
- Sponsor
- National and Kapodistrian University of Athens
Lewy Body Disease, Parkinson Disease Dementia
Learning to PERSEVERE: Peer Mentor Support and Caregiver Education in Lewy Body Dementia
The investigators propose to adapt, improve, and implement a peer mentor support and caregiver education (PERSEVERE) program to improve LBD-specific caregiving mastery.
- Conditions
- Lewy Body Disease, Parkinson Disease Dementia, Dementia With Lewy Bodies
- Trial name
- NCT04649164
- Testing
- Peer mentor support and caregiver intervention, Focus group to provide feedback on educational materials and mentoring program
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Cognitive Change
Impact of Challenging Engagement on Cognition in Older Adults
The study will enroll 90 participants in the "Impact of Challenging Engagement" study and assign them to one of three groups: high-demand photography, moderate-demand photography, and active placebo.
- Trial name
- engAGE (NCT03962439)
- Testing
- High-Demand Photography, Moderate-Demand Photography, At-Home Engagement
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Mild Cognitive Impairment (MCI), Dementia
Integration of VR and AR Dementia Prevention Health Education Progrom for Older Adults With Mild Cognitive Impairment
The goal of this randomized controlled trial is to evaluate the effectiveness of Virtual Reality (VR)-based cognitive health education for older adults with mild cognitive impairment (MCI) in Taiwan.
- Conditions
- Mild Cognitive Impairment (MCI), Dementia, Health Literacy, Self-Efficacy
- Trial name
- NCT06888986
- Testing
- VR Dementia Prevention Health Education Module
- Where
- Taiwan
- Volunteers
- 139 people
- Sponsor
- National Taiwan Normal University
PTSD, Depression
Trauma and Truth Interventions (NET) Versus Conflict Resolution and Social Skills Trainings for Vulnerable Youths in Northern Uganda
More than 300,000 children are fighting in armed conflicts all over the world. In Uganda an estimated number of 25,000 children have been abducted and forced to fight or work as porters and sex slaves on the side of the rebels…
- Conditions
- PTSD, Depression, Aggression
- Trial name
- NCT00893750
- Testing
- NET Truth Education, Conflict Resolution and Social Competence Skills, Traditional Ways of Coping
- Where
- Uganda
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Konstanz
Alzheimer's Disease
Safety and Effect on Memory of PYM50028 in Mild Alzheimer's Disease
The purpose of this study is to assess the effect of PYM50028 administered once daily for up to 12 weeks on the memory and other faculties of subjects with dementia due to Alzheimer's disease.
- Trial name
- NCT00130429
- Testing
- PYM50028
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- Phytopharm
Caregivers, Alzheimer's Disease
Meditation or Education for Alzheimer Caregivers
The goal is to determine how 6-week stress reduction techniques may decrease stress in primary caregivers of people with Alzheimer's disease. The 3 intervention programs are meditation, education, and respite care.
- Trial name
- NCT00558402
- Testing
- Meditation, Education, Respite only
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Oregon Health and Science University
Cognitive Impairment, Atrial Fibrillation
Atrial Fibrillation Follow-up Investigation to Recover Memory and learnING Trial
The objective of the study is to evaluate the effectiveness of cognitive training in people with atrial fibrillation and cognitive decline over 12-week cognitive training.
- Trial name
- AFFIRMING (NCT05374642)
- Testing
- cognitive training, active control
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Anzhen Hospital
Migraine Disorders, Headache Disorders
Predicting Migraine Attacks Based on Environmental and Behavioral Changes as Detected From the Smartphone
This study is conducted at the Henry Ford Health System with Lifegraph's behavioral monitoring technology, to examine the relation between migraine attacks and behavioral and environmental changes as detected from the smartphone…
- Conditions
- Migraine Disorders, Headache Disorders, Headache Disorders, Primary, Brain Diseases
- Trial name
- Migraine (NCT03762902)
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Lifegraph Ltd.
Alzheimer's Disease
Imaging of Cognition, Learning, and Memory in Aging
This investigation is designed to study how the brain functions when it is performing explicit memory tasks, and furthermore how the brain systems supporting performance on these tests change as a function of aging.
- Trial name
- NCT01297114
- Testing
- Florbetaben
- Where
- United States
- Volunteers
- 294 people, healthy volunteers welcome
- Sponsor
- Yaakov Stern
Alzheimer Disease, Preclinical Alzheimer's Disease
Amyloid Prediction in Early Stage Alzheimer's Disease Through Speech Phenotyping - FUTURE Extension
The primary objective of the study is to evaluate whether a set of algorithms analysing acoustic and linguistic patterns of speech, can predict change in Preclinical Alzheimer's Clinical Composite with semantic processing (PACC5)…
- Conditions
- Alzheimer Disease, Preclinical Alzheimer's Disease, Prodromal Alzheimer's Disease, Alzheimer's Disease (Incl Subtypes)
- Trial name
- FUTURE-US (NCT04951284)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Novoic Limited
Dementia
Evaluation of the PACE/PACENET BHL Caregiver Program
This project will conduct a retrospective clinical database review and a one-time research interview to evaluate outcomes among a sub-set of caregivers (CGs) who were enrolled in the Behavioral Health Laboratory (BHL) Caregiver…
- Trial name
- CREST (NCT02463708)
- Testing
- BHL COTP
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- University of Pennsylvania