Clinical trials: Delusions
Schizophrenia, Schizoaffective Disorder
Multi-disciplinary Treatment for Patients Experiencing First Episode of Psychosis
This study will assess the effectiveness of an experimental treatment intervention for adolescents and adults who have experienced their first episode of psychosis during the past two years.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder, Delusional Disorder
- Trial name
- NCT01216891
- Testing
- Multi-element, team-oriented treatment
- Where
- 2 sites in United States
- Volunteers
- 65 people
- Sponsor
- Research Foundation for Mental Hygiene, Inc.
Early Psychosis, Delusions
Intervention to Improve Coping With Negative Emotions in Patients With Psychosis (Feel-Good-Study)
The aim of the present single-centered pre-post study is to assess the feasibility and to investigate the putative efficacy of an emotion-oriented group intervention for patients with psychosis.
- Conditions
- Early Psychosis, Delusions, Emotional Distress, Self Esteem
- Trial name
- NCT04592042
- Testing
- Feel-Good- Group
- Where
- Germany
- Volunteers
- 36 people
- Sponsor
- Philipps University Marburg
Paranoia, Persecutory Delusion
Recovery From Paranoia: a Qualitative Exploration
Paranoia, the experience of undue or excessive mistrust, exists on a continuum which includes suspicious thoughts, ideas of reference, and persecutory delusions.
- Trial name
- NCT04824781
- Testing
- Qualitative interview
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- University of Oxford
Alzheimer's Disease, Dementia
A Study of the Effectiveness and Safety of Risperidone Versus Placebo in the Treatment of Patients With Hallucinations and Delusions Associated With Alzheimer's Disease
The purpose of this study is to assess the effectiveness and safety of risperidone (an antipsychotic medication) versus placebo for the treatment of patients with hallucinations and delusions associated with Alzheimer's disease.
- Trial name
- NCT00287742
- Testing
- risperidone
- Volunteers
- 33 people
- Sponsor
- Janssen Pharmaceutical K.K.
Delusions, Schizophrenia
Metacognitive Training in Schizophrenia
Over a period of 4 weeks, metacognitive training for schizophrenia patients (MCT), delivered both in a group and individually, is compared to cognitive remediation (CogPack training).
- Trial name
- MCT (NCT01029067)
- Testing
- Metacognitive training, Cognitive Remediation
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Psychotic Disorders, Schizophrenia
Development and Pilot Evaluation of Modified Cognitive Behavioural Therapy for Adolescents With Early Onset Psychosis
In the last decade cognitive behavioural therapy (CBT) approaches for patients with schizophrenia have been developed, which where especially designed to reduce severity of positive symptoms, readmission rates, treatment…
- Conditions
- Psychotic Disorders, Schizophrenia, Schizoaffective Disorder, Delusional Disorder
- Trial name
- mCBT (NCT00465920)
- Testing
- modified cognitive behavioural therapy (mCBT)
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- University of Cologne
Supported Accommodation Residents, Schizophrenia, Shizotypal and Delusional Disorders
Quantitative Investigation of Environment and Participation
Supported accommodation provides individuals with complex mental health difficulties the opportunity to maintain a tenancy with different levels of staff support provided to develop and maintain living skills and engage in social…
- Conditions
- Supported Accommodation Residents, Schizophrenia, Shizotypal and Delusional Disorders, Mood Affective Disorders, Disorders of Adult Personality and Behavior
- Trial name
- QIEP (NCT04106960)
- Testing
- No Intevention Used
- Where
- United Kingdom
- Volunteers
- 235 people
- Sponsor
- Queen Margaret University
Chronic Mental Illness, Chronic Physical Illness
Evaluation of the Texas Wellness Incentives and Navigation (WIN) Project
The Wellness Incentives and Navigation (WIN) project is designed to help improve health self-management and reduce the incidence and consequences of chronic disease among non-elderly adult Medicaid Supplemental Security Income…
- Trial name
- WIN (NCT02440906)
- Testing
- Patient-Directed Wellness Account, Health Navigator
- Where
- United States
- Volunteers
- 1,663 people
- Sponsor
- University of Florida
Psychosis Associated With Alzheimer's Disease
An Open-Label Study of ML-007C-MA in Adults With Alzheimer's Disease Psychosis
ML-007C-MA-222 is a 52-week, flexible-dose, open-label extension study designed to evaluate the long-term safety, tolerability, and effectiveness of ML007C-MA in participants with ADP who have completed the antecedent study (ie…
- Trial name
- NCT07459660
- Testing
- ML-007C-MA
- Where
- 8 sites in United States, Bulgaria and 1 more
- Volunteers
- 210 people
- Sponsor
- MapLight Therapeutics
Schizophrenia, Schizoaffective Disorder
Recovery From Psychosis in Schizophrenia - The Impact of Cognitive-Behavioral Therapy
This study examines the impact of Cognitive-Behavior Therapy (CBT) on symptoms, physiological arousal, stressors, and the ways to deal with them in individuals with schizophrenia and related disorders.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder
- Trial name
- NCT00791440
- Testing
- Cognitive-Behavior Therapy, Standard Psychiatric Treatment
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- New York State Psychiatric Institute
Persistent Delusional Disorder, Acute and Transient Psychotic Disorder, Unspecified
Enhancing Educational and Vocational Recovery in Adolescents and Young Adults With Early Psychosis Through Supported Employment and Education.
Psychotic disorders often develop a chronic course with devastating consequences for individuals, families, and societies usually with first onset during adolescence and early adulthood.
- Conditions
- Persistent Delusional Disorder, Acute and Transient Psychotic Disorder, Unspecified, Schizophrenia, Schizoaffective Disorder
- Trial name
- SEEearly (NCT05824117)
- Testing
- Individual Placement and Support (IPS)
- Where
- 6 sites in Germany
- Volunteers
- 184 people
- Sponsor
- Charite University, Berlin, Germany
Alzheimer's Disease Psychosis
ACP-204 in Adults With Alzheimer's Disease Psychosis
This is a master protocol for 3 independent, seamlessly enrolling, multicenter, randomized, double-blind, placebo-controlled, parallel-group studies in patients with ADP Substudy 1 (Phase 2) will evaluate efficacy and dose…
- Trial name
- NCT06159673
- Testing
- ACP-204
- Where
- 154 sites in United States, Brazil and 10 more
- Volunteers
- 1,074 people
- Sponsor
- ACADIA Pharmaceuticals Inc.
Schizophrenia, Delusional Disorders (ICD-10)
Cognitive Determinants of Psychoeducation and Information in Psychoses
The aim of the study is to examine whether the efficacy of psychoeducation in patients with schizophrenia or schizoaffective disorders is dependent on their cognitive performance level and if a preceding cognitive training can…
- Trial name
- COGPIP (NCT00646256)
- Testing
- COGPACK training, psychoeducation
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- German Research Foundation
Schizophrenia, Psychotic Disorders
Efficacy and Mechanisms of Change of an Emotion-oriented Version of Cognitive-behavioral Therapy for Psychosis
The aim of the present single-blind randomized-controlled therapy study is to assess the efficacy of a new form of Cognitive Behavioral Therapy for delusions with a focus on emotion regulation, improvement of self-esteem and…
- Conditions
- Schizophrenia, Psychotic Disorders, Delusions, Emotions
- Trial name
- CBTd-E (NCT02787135)
- Testing
- emotion-oriented Cognitive Behavior Therapy
- Where
- 2 sites in Germany
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Philipps University Marburg
Schizophrenia, Schizophreniform Disorder
Integrated Care in Psychotic Disorders With Severe Mental Illness
The study examine the effectiveness of an integrated care program including therapeutic assertive community treatment (ACT) for people with psychotic disorders fulfilling severe and persistent mental illness (SPMI, ACCESS-II…
- Conditions
- Schizophrenia, Schizophreniform Disorder, Schizoaffective Disorder, Delusional Disorder
- Trial name
- ACCESS-II (NCT01888627)
- Testing
- Integrated care
- Where
- Germany
- Volunteers
- 400 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Schizophrenia, Schizoaffective Disorder
Research Into Antipsychotic Discontinuation and Reduction Trial
Psychosis and schizophrenia are common and costly mental health problems. Psychosis is the name given to a group of mental conditions in which cause people to perceive or interpret things differently from those around them.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Delusional Disorder, Schizophreniform Disorders
- Trial name
- NCT03559426
- Testing
- Antipsychotic Reduction, Antipsychotic Maintenance
- Where
- United Kingdom
- Volunteers
- 253 people
- Sponsor
- University College, London
Paranoia in People With Schizophrenia-spectrum Diagnosis
Computerised Interventions for Thinking and Anxiety in Delusions (CITADEL) Trial
People with a schizophrenia spectrum diagnosis often experience distressing worries or beliefs about others intending to cause them harm (also known as paranoia).
- Trial name
- CITADEL (NCT01920685)
- Testing
- Anxiety intervention
- Where
- 2 sites in United Kingdom
- Volunteers
- 25 people
- Sponsor
- King's College London
Parkinson Disease, Parkinson Disease Psychosis
Characterization and Progression of Minor Phenomena in Parkinson's Disease (PD)
Parkinson's disease psychosis encompasses a range of symptoms, including minor phenomena, frank hallucinations, and delusions. Minor phenomena include passage hallucinations (fleeting sense of a person, animal or object passing…
- Conditions
- Parkinson Disease, Parkinson Disease Psychosis, Hallucinations, Delusion
- Trial name
- NCT05240339
- Testing
- Observation of minor phenomena
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Rochester
Schizophrenia, Hallucinations
Evaluation of Internet-based Cognitive Behavioral Self-help Treatments for People With Psychosis
Schizophrenia is a severe mental disorder which is accompanied by an enormous individual and societal burden. Despite established efficacy of cognitive behavioral therapy for psychosis (CBTp), its dissemination into routine…
- Conditions
- Schizophrenia, Hallucinations, Persecutory Delusion
- Trial name
- EviBaS (NCT02974400)
- Testing
- Internet-based, CBT-oriented, guided self-help
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 101 people
- Sponsor
- University of Bern
Schizophrenia
Using D-cycloserine to Enhance the Benefits of Cognitive Behavioral Therapy for Schizophrenia
This study will examine whether pretreatment with D-cycloserine before cognitive behavioral therapy can reduce impairments still present in people with stable cases of schizophrenia as well as determine which traits make…
- Trial name
- NCT00742079
- Testing
- D-cycloserine, Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Massachusetts General Hospital