Clinical trials: Deep Endometriosis
Deep Infiltrating Endometriosis (DIE), Infertility
Ultra-Long GnRH-a Pretreatment for FET Outcomes in Patients With Deep Infiltrating Endometriosis
Deep infiltrating endometriosis is a severe form of endometriosis that may reduce fertility and negatively affect pregnancy outcomes after assisted reproductive treatment.
- Trial name
- DIE-GnRHa-FET (NCT07696351)
- Testing
- Triptorelin (GnRH agonists), Hormone Replacement Therapy (HRT)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Li-jun Ding
Endometriosis, Dysuria
Percutaneous Posterior Tibial Nerve Stimulation in Post-operative Voiding Dysfunction After Deep Endometriosis Surgery
Symptomatic endometriosis can be responsible for urinary problems as well as symptoms of clinical bladder hyperactivity and/or symptoms of bladder pain before or during miction that can persist after bladder voiding.
- Trial name
- NCT04228692
- Testing
- Self-catheterization only, Posterior tibial nerve stimulation + self-catheterization
- Where
- France
- Volunteers
- 4 people
- Sponsor
- Hospices Civils de Lyon
Deep Endometriosis, Recto Vaginal Node
Estimation of Vascularization After Treatment of Deep Rectovaginal Endometriosis Node by Rectal Shaving
Indocyanine green is a dye, using in surgery to bring out the intraoperative evaluation of tissue perfusion. After intravenous injection of indocyanine green, using a near infrared light, the vascularisation becomes fluorescent.
- Trial name
- INDIE (NCT03080558)
- Testing
- Indocyanine green
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Clermont-Ferrand
Endometriosis, Rectum
Endoscopic Rectal UltraSound With Elastosonography and Contrast in Deep Pelvic Endometriosis With Bowel Involvement
The aim of the study will be to determine the diagnostic and prognostic value of elastosonography and the use of the contrast agent (Sonovue®) in the endoscopic ultrasound exploration of deep pelvic endometriosis.
- Trial name
- NCT03138954
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Société Française d'Endoscopie Digestive
Endometriosis
Deep Neural Network Stratification for Use Detecting Endometriosis in Women Affected by Chronic Pelvic Pain (EndoCheck)
The goal of this observational study is to determine the clinical validity of a deep neural network algorithm that utilizes protein biomarker detection of Endometriosis - "EndoCheck" - as an "aid in diagnosis" for endometriosis…
- Trial name
- NCT05245695
- Testing
- Observational study, no intervention
- Where
- 10 sites in United States
- Volunteers
- 1,200 people
- Sponsor
- Aspira Women's Health
Indocyanine Green (ICG), Robotic Surgical Procedure
Assessing the Efficacy of Indocyanine Green for Ureter Identification During Robot-Assisted Surgery in Advanced-Stage Endometriosis
The goal of this side-randomized, self-controlled trial, 1-site study is to explore the efficacy of Indocyanine Green Fluorescence (ICG) for Intraoperative Ureter Identification During Robot-Assisted Single-Site Surgery in…
- Conditions
- Indocyanine Green (ICG), Robotic Surgical Procedure, Deep Infiltrating Endometriosis (DIE), Endometriosis Pelvic
- Trial name
- NCT07144904
- Testing
- Indocyanine Green (ICG)-Assisted Ureteral Identification, Standard Ureteral Identification without ICG
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Baylor College of Medicine
Pelvic Endometriosis, Endometriosis Outside Pelvis
Near-infrared Fluorescence Imaging as a Supportive Tool for Localisation of Deep Infiltrating Endometriosis During Laparoscopy
The aim of the study is to establish a new and more accurate method to visualize the peritoneal changes caused by endometriosis using Indocyanine Green mediated fluorescence imaging.
- Trial name
- NCT03332004
- Testing
- Indocyanine Green
- Where
- Italy
- Volunteers
- 27 people
- Sponsor
- Catholic University of the Sacred Heart
Endometriosis, Deep Endometriosis
Retrospective Analysis of Results of Surgery for Deep Bowel Endometriosis
identification of patients operated becaus of bowel endometriosis at the endometriosis center, University Hospital Muenster, Germany, starting 2009, Analysis of Patient history, surgical procedurie, intraoperative complications…
- Conditions
- Endometriosis, Deep Endometriosis, Bowel Endometriosis, Reproductive Issues
- Trial name
- NCT04669769
- Testing
- interview
- Where
- Germany
- Volunteers
- 151 people
- Sponsor
- University Hospital Muenster
Endometriosis
Quality of Life in Patients Undergoing Colorectal Resection for Deep Infiltrating Endometriosis
The aim of this study is to evaluate the quality of life of patients undergoing colorectal resection for deep infiltrating endometriosis of the bowel.
- Trial name
- ENDO-RESECT (NCT03824054)
- Testing
- colorectal resection
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Catholic University of the Sacred Heart
Endometriosis
TENS Self-applied in the Complementary Treatment of Deep Endometriosis
Objective: to evaluate the effectiveness of Transcutaneous Electrical Nerve Stimulation (TENS) self-applied for the treatment of pain and the impact of this therapy on quality of life and sexuality of women with deep…
- Trial name
- tici_mira (NCT02769052)
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- University of Campinas, Brazil
Gynecological Surgeries
A Real-World Study to Evaluate the Clinical Performance and Safety of da Vinci SP Surgical System for Single-Port Gynecological Surgeries(SPiM-RWS-GYN)
Study name：A Real-World Study to Evaluate the Clinical Performance and Safety of da Vinci SP Surgical System for Single-Port Gynecological Surgeries Study purpose：This clinical trial is a real-world study to evaluate the clinical…
- Trial name
- NCT06082011
- Testing
- da Vinci SP Surgical System
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Ruijin Hospital
Deep Infiltrating Endometriosis
Impact of Deep Endometriosis Surgery on Bladder Function
It has been demonstrated that ligaments, both cardinal and uterosacral contain a considerable amount of autonomic nerve tissues.
- Trial name
- NCT02238678
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
Endometriosis
Improvement in Quality of Life and Pain Scores After Laparoscopic Management of Deep Infiltrating Endometriosis
This is a retrospective cohort study that evaluates the postoperative pain findings of a consecutive series of laparoscopic surgeries for deep infiltrating endometriosis (DIE).
- Trial name
- NCT04062916
- Testing
- BSGE pelvic pain questionnaire and VAS scores
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Acibadem Fulya Hastanesi
Endometriosis
Feasibility and Potential Aids of Intra-operative Endo-vaginal Ultrasound When Performing Rectal Shaving for Endometriosis
The protocol of this study consists in the inclusion of patients with endometriosic rectal involvement with a scheduled intervention.
- Trial name
- ECHOENDO (NCT05499884)
- Testing
- Endovaginal ultrasound
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Lille
Endometriosis, Infertility
Impact of Complete Surgery of Colorectal Deep Infiltrating Endometriosis on Fertility
The ENDOFERT Study is an open, multicenter, randomized, parallel-group, controlled trial. This study includes patients presenting colorectal DIE and infertility.
- Trial name
- ENDOFERT (NCT02948972)
- Testing
- complete surgery, In vitro fertilization without surgery
- Where
- 5 sites in France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Lille
Endometriosis, Deep Endometriosis
Ureteric Identification Using Indocyanine Green Dye Versus Conventional Ureteric Stenting to Reduce Post-operative Pain and Surgical Morbidity During Endometriosis Surgery
Endometriosis is a common (around 1 in 10 women), non-cancerous condition where tissue similar to the womb lining is found growing elsewhere, most commonly inside the pelvis.
- Trial name
- ICE (NCT06852248)
- Testing
- Ureteric stenting, Indocyanine green (ICG) dye
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- University Hospitals of North Midlands NHS Trust
Endometriosis
Treatment by HIFU With Focal One® of Posterior Deep Infiltrating Endometriosis Lesions With Intestinal Involvement.
Deep invasive endometriosis (DIE) includes lesions of the rectosigmoid. Theses lesions are associated with painful symptoms that can alter quality of life.
- Trial name
- NCT03613298
- Testing
- HIFU (Focal One®)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- EDAP TMS S.A.
Deep Infiltrating Endometriosis, Pelvic Pain, Dysmenorrhea Dyspareunia
Nerve Fiber Density in DIE Nodules & Pelvic Pain
Deep infiltrating endometriosis (DIE) is a highly symptomatic form of endometriosis linked to severe dysmenorrhea, dyspareunia, dyschezia, dysuria, and chronic pelvic pain.
- Trial name
- DIENerveDens (NCT07274956)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Deep Endometriosis, Recurrences
Recurrences After Surgery for Deep Endometriosis Depending on the Involvement of the Surgical Margins in the Specimen
The recurrence of endometriosis after surgery a formidable challenge for the gynecologist. Recurrence rates reported in the literature are very high, being 21.5% at 2 years and 40-50% at 5 years.
- Conditions
- Deep Endometriosis, Recurrences, Margins in the Specimen, Laparoscopy
- Trial name
- NCT01949597
- Testing
- laparoscopic surgery for deep endometriosis
- Where
- Spain
- Sponsor
- Fundacion Dexeus
Endometriosis, Deep Endometriosis
The Association Between Deep Endometriosis and the Occurrence of Colorectal Carcinoma
The goal of this study is to identify the molecular or genetic mechanisms that may predispose patients with bowel endometriosis to an increased risk of colorectal carcinoma.
- Conditions
- Endometriosis, Deep Endometriosis, Bowel Endometriosis, Colorectal Carcinoma
- Trial name
- NCT07386431
- Volunteers
- 30 people
- Sponsor
- University Medical Centre Ljubljana