Clinical trials: Deep Caries
Caries; Dentin
SMART With Different Modifications in Asymptomatic Deep Carious Lesions of Primary Molars.
This study aimed to evaluate the clinical success of the 'Silver Modified Atraumatic Restorative Technique '(SMART) with different modifications in asymptomatic deep carious lesions of primary molars.
- Trial name
- NCT06645860
- Testing
- SDF+KI+LED Light 20s, SDF+KI
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Deep Dental Caries
Outcomes of Partial Pulpotomy Treatment in Cariously Exposed Teeth
The aim of this clinical trial is to learn how successful Biodentine and Theracal PT dental filling materials are in treating deep tooth decay in adults. It will also provide information about post-treatment pain.
- Trial name
- NCT06802549
- Testing
- Biodentine (calcium silicate-based cement) (Septodont, Saint Maur de Fossés, France), Theracal PT (resin modified calcium silicate-based cement) (Bisco Inc., Schaumburg, IL, USA)
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Firat University
Pulpitis - Irreversible
Pulpotomy vs Root Canal Treatment for Teeth With Symptomatic Irreversible Pulpitis
This study is a randomised controlled trial for complete pulpotomy as an alternative to root canal treatment for teeth with clinical diagnosis of symptomatic irreversible pulpitis (i.e.
- Trial name
- NCT05964933
- Testing
- Complete Pulpotomy, Pulpectomy and Root Canal Treatment
- Where
- Singapore
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Deep Caries
Indirect Pulp Treatment in Primary Teeth
Conservative approaches such as indirect pulp capping techniques became popular over the last years for the management of deep carious lesions.
- Trial name
- NCT04763057
- Testing
- NeoPUTTY MTA, calcium hydroxide
- Volunteers
- 88 people
- Sponsor
- Cairo University
Deep Caries
Indirect Pulp Treatment of Young Permanent Molars Using Photo-Activated Oral Disinfection Versus Calcium Hydroxide
This study aimed to assess the clinical and radiographic success for photo-activated oral disinfection (PAD) and calcium hydroxide in indirect pulp treatment (IPT) of young permanent molars.
- Trial name
- NCT03631277
- Testing
- photo-activated oral disinfection, Calcium Hydroxide
- Volunteers
- 32 people
- Sponsor
- Cairo University
Deep Caries, Pulp Exposure, Dental
Selective Removal to Soft Dentine vs Selective Removal to Firm Dentine for Deep Posterior Caries Lesions
Removal of infected dentin contaminated with bacteria and remaining affected dentin detected as firm is the conventional strategy for the management of cavitated caries lesions.
- Conditions
- Deep Caries, Pulp Exposure, Dental, Dental Caries
- Trial name
- NCT04052685
- Testing
- Selective removal to soft dentin (SRSD), Selective removal to firm dentine (SRFD)
- Where
- Turkey (Türkiye)
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- burcu gözetici
Dental Caries
Investigation of the Effect of Deep Margin Elevation Technique on the Clinical Performance of Endocrown Restorations Produced by Computer-Aided Design and Computer-Aided Manufacturing (CAD/CAM) System
The aim of this clinical study is to investigate the impact of the deep margin elevation technique on the clinical performance of CAD/CAM endocrown restorations in deep Class II cavities.
- Trial name
- NCT06222918
- Testing
- Deep Margin Elevation (G-ænial Universal Injectable)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dentin Caries
Evaluation of the Remineralizing and Antibacterial Effect of Natural Versus Synthetic Materials on Deep Carious Dentin
The present study will be performed to evaluate: 1. The remineralizing effect of natural materials versus synthetic materials on deep carious dentin after selective caries removal. 2.
- Trial name
- NCT04145102
- Testing
- hesperidine, propolis, silver diamine fluoride
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Deep Dental Caries
Attitude and Practice for Deep Caries Management Between Egyptian and Indian Dentists : a Cross Sectional Study
Study type: Observational Study To assess and compare the attitudes, and practices of dentists in Egypt and India regarding the removal of deep dentin caries and preferred restorative strategies.
- Trial name
- NCT06806254
- Where
- Egypt
- Volunteers
- 766 people, healthy volunteers welcome
- Sponsor
- Cairo University
Symptomatic Irreversible Pulpitis (SIP), Extremely Deep Caries
Outcome of Partial Pulpotomy in Permanent Mandibular Molars With Symptomatic Irreversible Pulpitis After Wound Lavage With Calcium Hypochlorite or Sodium Hypochlorite
The aim of this randomised control trial is to compare the effect of wound lavage using 2.5% Ca(OCl)₂ and 2.5% NaOCl on the outcome of partial pulpotomy in mature permanent mandibular molars with symptomatic irreversible pulpitis…
- Trial name
- NCT07748676
- Testing
- Partial pulpotomy using calcium hypochlorite as wound lavage agent, Partial pulpotomy using sodium hypochlorite as wound lavage agent
- Where
- India
- Volunteers
- 106 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
DME, Dental Caries
The Effect of Bulk Filling Flowable Composite on Caries Recurrence in Deep Marginal Elevation: A Randomized Clinical Trial
Deep marginal elevation usinge a bioactive dental material in deep subgingival Class II restorations, S-PRG filler-containing materials offer significant benefits due to their bioactive properties, Their ability to release…
- Conditions
- DME, Dental Caries, Dental, Deep Margin Elevation
- Trial name
- NCT06900868
- Testing
- Assigned Interventions
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Dental Caries
Evaluation of Antimicrobial Photodynamic Therapy as an Adjunct Treatment of Deep Carious Lesions in Children
This project aims to evaluate the effect of antimicrobial photodynamic therapy (aPDT) in deep carious lesions. This study was approved by the Research Ethics Committee and was conducted on 53 patients between 3 and 12 years.
- Trial name
- NCT02908789
- Testing
- Antimicrobial photodynamic therapy (aPDT), Without Antimicrobial phothodynamic therapy
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Dental Caries, Dental Pulp Exposure
Stepwise and One Step Techniques In Deep Dentin Lesion
This double blind, randomized, controlled clinical trial aimed to observe the success of stepwise (SW) and one step (OneS) excavation techniques in the management of deep dentin caries.
- Trial name
- NCT04351048
- Testing
- Stepwise Excavation, One Step Excavation
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- TIJEN PAMIR
Deep Carious Lesions, Partial Caries Removal
This Study Aims to Clinically Assess and Radiographically Measure the Formed Dentin Bridge Over the Pulp, Utilizing Three-dimensional Imaging Following the Application of a Bioactive Restorative System Versus a Conventional Restorative System After Selective Caries Removal to Soft Dentin Over 2
This clinical trial aims to evaluate dentin bridge formation over the pulp following selective caries removal in permanent teeth with deep carious lesions (ICDAS scores 5-6).
- Conditions
- Deep Carious Lesions, Partial Caries Removal, Dentin Bridge
- Trial name
- NCT07171775
- Testing
- Experimental - Bioactive Restorative System, Active Comparator -Conventional Restorative System
- Volunteers
- 66 people
- Sponsor
- Cairo University
Dental Caries
Evaluation of the Antibacterial Effect of Laser Diode and Zinc Oxide Nano Particles in Cavity Disinfection
this is a randomized controlled clinical trial, evaluating the antibacterial effect of laser diode and zinc oxide nano-particles when used as cavity disinfectants.Two groups, including 15 patients each, will be randomly allocated…
- Trial name
- NCT03478150
- Testing
- zinc oxide nano-particles, laser diode
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, Pulp Exposure, Dental
Clinical Study Evaluating Solventum™ Vitrebond™ Pulp Protect Liner/Base for Direct Capping of Pulpal Exposure
This research study is looking at the safety and effectiveness of Solventum™ Vitrebond™ Pulp Protect Liner/Base for direct pulp capping (DPC) on permanent teeth that have pulp exposure due either to deep cavities, trauma, or…
- Conditions
- Dental Caries, Pulp Exposure, Dental, Tooth Decay, Dental Decay
- Trial name
- NCT07231237
- Testing
- Vitrebond™ Pulp Protect Liner/Base
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Solventum US LLC
Moderate Pulpitis, Severe Pulpitis
Outcome of Partial Pulpotomy in Moderate and Severe Pulpitis
The aim of the study is to compare the outcome of Partial Pulpotomy in mature permanent teeth with moderate and severe pulpitis.
- Conditions
- Moderate Pulpitis, Severe Pulpitis, Extremely Deep Caries
- Trial name
- NCT07123025
- Testing
- Partial Pulpotomy in Moderate Pulpitis, Partial Pulpotomy in Severe Pulpitis
- Where
- India
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Deep Caries
Pre-operative Radiograph of Deep Carious Lesions as a Predictive Tool for Pulpal Exposure
Preserving pulpal vitality is a major challenge when excavating deep caries lesions without severe symptomatology. Pulpal exposure alters success of the treatment (dropping from 93% for indirect pulp treatment with selective…
- Trial name
- R2 (NCT04607395)
- Testing
- pre-operative radiograph
- Where
- France
- Volunteers
- 358 people
- Sponsor
- Hospices Civils de Lyon
Pulpotomy, Deep Caries
Clinical and Radiographic Evaluation of Bioceramic Putty MTA Versus MTA in Pulpotomy of Immature Permanent Molars
The present study aims to evaluate the clinical and radiographic success of bioceramics putty MTA versus MTA in the pulpotomy of immature permanent molars The main question it aims to answer is: Will the biocermaics putty MTA…
- Trial name
- MTA (NCT06219824)
- Testing
- premixed Bio-ceramic MTA, Conventional MTA
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Indirect Pulp Treatment
The Use of 2% Chlorhexidine Gluconate With Mineral Trioxide Aggregate in Indirect Pulp Treatment of Primary Molars
The aim of this study was to compare the clinical and radiographic success rates of indirect pulp treatment (IPT) performed by combining 2% chlorhexidine gluconate with mineral trioxide aggregate (MTA) versus IPT performed with…
- Trial name
- NCT04770792
- Testing
- 2% chlorhexidine gluconate with mineral trioxide aggregate., Mineral trioxide aggregate.
- Where
- Saudi Arabia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University