Clinical trials: Deconditioning
Deconditioning, Orthopedic Fractures
This Study Aims to Measure the Effect of Acute Hospitalisation on the Physical and Cognitive Functioning of Older Orthopaedic Patients (Aged 65 or Above).
This study aims to investigate the impact of hospitalisation on physical and cognitive performance in patients aged 65 and older admitted with an orthopaedic injury.
- Conditions
- Deconditioning, Orthopedic Fractures, Hospital Associated Deconditioning, Orthopaedic Injuries
- Trial name
- NCT06932224
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- University of Southampton
Geriatric, Haematologic Neoplasm
Feasibility of Physical Activity in Older Adults With Haematological Malignancies: ACCES Study
The aim of this study is to implement a simple and unsupervised home-based physical activity (PA) program for cancer patients in 2 oncogeriatric units in Toulouse Hospital (day hospital and week hospital).
- Trial name
- ACCES (NCT06102876)
- Testing
- Physical activity (PA) program
- Where
- France
- Volunteers
- 69 people
- Sponsor
- University Hospital, Toulouse
Old Injury
Prehabilitation & Rehabilitation in Oncogeriatrics: Adaptation to Deconditioning Risk and Accompaniment of Patients' With Cancer
With the conjunction of increased life expectancy and the increasing incidence of cancer with aging, older patient represent an increasing proportion of cancer patients.
- Trial name
- PROADAPT (NCT03659123)
- Testing
- standardized geriatric intervention
- Where
- 10 sites in France
- Volunteers
- 148 people
- Sponsor
- Hospices Civils de Lyon
Immune Thrombocytopenic Purpura
Physical Fitness of Children, Adolescents and Young Adults With Immune Thrombocytopenic Purpura
Patients with chronic immune thrombocytopenic purpura (ITP) live with an anxiety-inducing risk of haemorrhage that is unpredictable over several months or years.
- Trial name
- ITP-CPET (NCT07310342)
- Testing
- IPT-CPET
- Where
- 5 sites in France
- Volunteers
- 53 people
- Sponsor
- University Hospital, Bordeaux
Low Back Pain, Mechanical
Physical Deconditioning in COVID-19 Positive Patients and Non-Specific Low Back Pain
The purpose of this study is to take advantage of cohorts of patients followed for Coronavirus Disease 2019 (COVID19) expected to present poor physical fitness as the consequence of COVID19 to explore the relationship between…
- Trial name
- Phydel (NCT04990518)
- Where
- Switzerland
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Rehabilitation, Deconditioning
AI-Assisted TelerehabiLitAtion System (ATLAS) for Post-discharge Continuation of Rehabilitative Care
The study team proposes ATLAS (AI-Assisted TelerehabiLitAtion System) a two-part solution. The first-Rebee AI-assisted telerehabilitation device-assists in inpatient rehabilitation, and allows patients to continue with their…
- Trial name
- NCT06683963
- Testing
- Rebee
- Volunteers
- 450 people
- Sponsor
- SingHealth Community Hospitals
Sarcopenia in Elderly, Hospital Associated Deconditioning
Preventing Hospital Associated Disability in Older Patients: Individualized Nutrition and Exercise Strategy, a Feasibility Study
Aproximately a third of persons older than 70 years lose physical function and ability to take care of themselves during a stay at a hospital. This is associated to an increased risk of readmission and mortality.
- Conditions
- Sarcopenia in Elderly, Hospital Associated Deconditioning, Malnutrition Elderly, Physical Function
- Trial name
- PrevHAD FS (NCT07124338)
- Testing
- Exercise, supervised
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- Bispebjerg Hospital
Fractures, Bone, Stroke
Tele-Rehabilitation Pilot Evaluation Study
A proof of concept randomized controlled trial (RCT) only evaluated the National University of Singapore's (NUS) T-Rehab tele-rehabilitation (TR) system at a home setting where rehabilitation was provided on an individual level.
- Conditions
- Fractures, Bone, Stroke, Lower Limb Joint Replacement (Hip or Knee), Lower Limb Amputation
- Trial name
- NCT03409354
- Testing
- Tele-rehabilitation, Usual care
- Where
- Singapore
- Volunteers
- 14 people
- Sponsor
- National University of Singapore
Mobility Limitation, Spinal Fusion
Physical Therapy Using Virtual Reality/Augmented Reality
The purpose of this study is to determine if non-invasive distracting devices (Virtual Reality (VR) headset, Augmented Reality (AR) Headset) are more effective than the standard of care (i.e., no technology-based distraction) for…
- Conditions
- Mobility Limitation, Spinal Fusion, Acute Pain
- Trial name
- NCT03874507
- Testing
- Virtual Reality/Augmented Reality Headset
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- Stanford University
Atrophy, Muscular, Atrophy, Disuse
Blood Flow Restricted Electrical Stimulation During Immobilisation
Following injury or surgery to a limb, it is often immobilised to allow tissue healing. Short periods of disuse cause loss of muscle size and strength and impaired mechanical properties of tendons, which leads to reduced…
- Trial name
- NCT05093985
- Testing
- Neuromuscular electrical stimulation with blood flow restriction
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- St Mary's University College
Osteoarthritis
Home Telerehabilitation for Deconditioned Older Adults
The purpose of this study is to develop a home exercise program for patients 60 years of age and over who are deconditioned following their discharge from the hospital, or recruited from GLA outpatient clinics.
- Trial name
- NCT00386256
- Testing
- Health Buddy, Home telehealth technology, Telephone counseling
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- US Department of Veterans Affairs
Older Adults, Physical Deconditioning
Progressing Home Health Rehabilitation for Older Adults
This research study explores the effects of a progressive, multi-component intervention following a stay in the hospital or rehabilitation facility.
- Trial name
- NCT02905370
- Testing
- Progressive Multi-Component (PMC), Enhanced Usual Care (EUC)
- Where
- United States
- Volunteers
- 353 people
- Sponsor
- University of Colorado, Denver
Frailty, Stroke
Body Composition, Frailty, and Function in Rehabilitation
The investigators are investigating if body composition measures - in particular muscle mass, body fat, and something called the phase angle - are able to reliably predict functional outcomes for patients who are in an acute…
- Conditions
- Frailty, Stroke, Debility Due to Disease
- Trial name
- NCT06527742
- Where
- Singapore
- Volunteers
- 345 people
- Sponsor
- Changi General Hospital
Hospital Associated Disability, Immobility
Targeting Muscle Strength Loss Due to Hospitalization in Older Adults by Blood-flow Restriction Combined With an Electromyography-driven Serious Game.
This study investigates a new training method designed to help older adults preserve their muscle strength during hospitalization.
- Conditions
- Hospital Associated Disability, Immobility, Older Adults (65 Years and Older)
- Trial name
- GHOSTLY+ (NCT07294131)
- Testing
- Gamified isometric strength training with blood flow restriction, Standard Physiotherapy
- Where
- 3 sites in Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Heart Defects, Congenital, Adolescent
Rehabilitation of Adolescents and Young Adults With Congenital Heart Diseases
The investigators aim to measure the impact of a rehabilitation program in congenital cardiology in terms of health related quality of life.
- Conditions
- Heart Defects, Congenital, Adolescent, Young Adult
- Trial name
- QUALIREHAB (NCT03690518)
- Testing
- Cardiac rehabilitation
- Where
- 17 sites in France
- Volunteers
- 142 people
- Sponsor
- University Hospital, Montpellier
Weightlessness, Weightlessness; Adverse Effect
A New Nutritional Countermeasure to Prevent the Deconditioning Induced by 60 Days of Antiorthostatic Bed Rest
The objective of this study is to investigate whether the cocktail of natural antioxidants XXS-2A-BR2 comprising vitamin E and coupled with omega-3 helps to prevent and / or reduce the deleterious effects induced by long term…
- Trial name
- LTBRCocktail (NCT03594799)
- Testing
- Bed Rest Control Group, Cocktail intervention
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre National d'Etudes Spatiales
Pancreas Adenocarcinoma (MSI-H), Deconditioning
Exercise to Improve Outcomes in Pancreatic Cancer
Pancreatic cancer surgery (Whipple's procedure) is a major operation that can lead to reduced physical fitness, delayed recovery, and difficulty starting chemotherapy after surgery.
- Trial name
- ExO-PanC (NCT07710495)
- Testing
- ExO-PanC Personalised Exercise Programme
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- University of Surrey
Old Age; Debility
Safety and Feasibility of a Novel In--Bed Resistance Training Device in Elderly Inpatients
The purpose of this study is to decrease deconditioning of elderly inpatients in acute care institutions and to assess the safety and feasibility of a newly developed resistance training device.
- Trial name
- NCT04026802
- Testing
- In-Bed Resistance Training Device, Standard of Care
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- NYU Langone Health
Haematological Cancer, Healthy
Pulsed Electromagnetic Fields in Preventing Physical Deconditioning in Patients Undergoing Prolonged Hospitalization
The goal of this clinical trial is to examine if pulsed electromagnetic fields (PEMF) can prevent or decrease physical deconditioning associated with prolonged hospitalisation and immobility of haematology patients.
- Trial name
- PEMF (NCT06744764)
- Testing
- PEMF (1mT), PEMF (0mT)
- Where
- 2 sites in Singapore
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Myocardial Injury
Myocardial Physiology And Microanatomy In Individuals Undergoing Heart Surgery
The main focus of the project is to determine to what degree myocardial energy metabolism is linked to impaired function in human cardiomyocytes, whether exercise training and remote ischemic preconditioning can restore…
- Trial name
- TRIMRIPC (NCT01308138)
- Testing
- Exercise training, remote ischemic preconditioning
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Norwegian University of Science and Technology