Clinical trials: Decision-Making
Healthy Volunteer
A Cross-Cultural Assessment of the Motivations of Healthy Participants in Phase I Research
Background: Individuals often participate in clinical trials to seek new therapies and free medical treatments for their illnesses or chronic conditions.
- Trial name
- NCT01485250
- Where
- 3 sites in United States, Belgium and 1 more
- Volunteers
- 1,278 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Scar; Previous Cesarean Section, Vaginal Birth After Cesarean
University of North Carolina-Healthwise Partnership Project on Birth Options Decision Aid
This is pilot quasi-experimental study of women with one or two prior cesarean deliveries who are now pregnant and eligible for a trial of labor after cesarean delivery, to assess whether a decision aid, providing knowledge about…
- Conditions
- Scar; Previous Cesarean Section, Vaginal Birth After Cesarean, Decision Making, Shared
- Trial name
- B-READY (NCT04053413)
- Testing
- Decision Aid
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Solid, Liquid, Central Nervous System Tumors
Next Generation Sequencing of Normal Tissues Prospectively in Pediatric Oncology Patients
The development of next generation sequencing (NGS) techniques, including whole genome (WGS), exome (WES) and RNA sequencing has revolutionized the ability of investigators to query the molecular mechanisms underlying tumor…
- Trial name
- NCT02530658
- Testing
- Study Introduction Visit, Informed Consent Visit, Informed Consent Follow-Up Visit
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- St. Jude Children's Research Hospital
Contraception, Decision Making
Computerized Contraceptive Decision Aid
The purpose of this study is to conduct a randomized clinical trial of a web-based contraceptive decision aid compared to routine contraceptive counseling to evaluate the effect of the contraceptive decision aid on the…
- Conditions
- Contraception, Decision Making, Satisfaction, Evaluation
- Trial name
- CDM RCT (NCT01479985)
- Testing
- CDM Tool
- Volunteers
- 253 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Acute Cystitis
Dispensing of Antibiotics in Pharmacies for Cystitis According to a Delegation Protocol, Impact of a Decision Support Tool. PHARIBO: PHarmacy and Resolved Antibiotherapy for Urinary Tract Infections
The purpose of this trial is to demonstrate that when treating acute cystitis without risk of complication, pharmacists may use share Decision Making tool to help patients to better understand the stakes of taking antibiotics and…
- Trial name
- PHARIBO (NCT07118748)
- Testing
- Share making decision tool, Delegation protocol
- Where
- 26 sites in France
- Volunteers
- 506 people
- Sponsor
- University Hospital, Bordeaux
Coronary Artery Disease
Observational Study of Angiographic Coregistered Optical Coherence Tomography in Patients Undergoing PCI
To define and evaluate the impact of angiographic coregistered OCT on physicians decision-making through prospective data collection in PCI procedures.
- Trial name
- NCT02919943
- Testing
- Percutaneous Coronary Intervention
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Charite University, Berlin, Germany
Stress
The Effect of Mindfulness Program on Clinical Stress Nursing Students
Nurses are important members of the team in the provision of health services, which determine and help the health needs of the individual, family and society, while working towards the protection and development of health, as…
- Trial name
- NCT06259955
- Testing
- Mindfulness
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Gazi University
Lung Neoplasms
TELESCOPE- TELEhealth Shared Decision-making COaching
Hypothesis 1a: The investigators anticipate that navigator decision coaching, compared to enhanced usual care (EUC) will result in higher quality SDM for lung cancer screening (LCS )(primary outcome), greater knowledge of lung…
- Trial name
- NCT05491213
- Testing
- TELESCOPE, Remote Decision Coaching with Navigation Intervention
- Where
- 2 sites in United States
- Volunteers
- 594 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Coagulopathy, Thromboelastography
ROTEM Interpretation AI vs Experts
This prospective multicenter observational study aims to evaluate the agreement between artificial intelligence (AI)-based interpretation and expert interpretation of rotational thromboelastometry (ROTEM) findings in clinically…
- Conditions
- Coagulopathy, Thromboelastography, Agreement
- Trial name
- ROTEMAI (NCT07502950)
- Testing
- Large Language Model (LLM) artificial intelligence assesment
- Volunteers
- 400 people
- Sponsor
- Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.
Alzheimer Disease, Neurodegenerative Diseases
Decision-making, Ethical Consent, and Interactive Dialogue in Ongoing Neurocognitive Decline - DECISION
DECISION Study - Summary Title: Decision-making, Ethical Consent, and Interactive Dialogue in Ongoing Neurocognitive Decline The DECISION study aims to develop and validate a simplified yet robust tool for assessing the capacity…
- Trial name
- DECISION (NCT07514520)
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Healthy Volunteers, Obesity
Effect of Ghrelin on Decision-Making
This study evaluates the effect of the "hunger hormone" ghrelin on human decision-making. Participants will be given an injection of ghrelin or saline on different study days and will then be asked to make a series of…
- Trial name
- NCT03198143
- Testing
- Ghrelin, Saline
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Jenny Tong, MD, MPH
Inflammatory Bowel Diseases
IBD Shared Decision Making Intervention
The purpose of this clinical trial is to implement a multi-component shared decision making intervention for families of children with IBD.
- Trial name
- NCT03228615
- Testing
- SDM Intervention
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Neoplasms, Heart Failure
Preparing Family Caregivers to Make Medical Decisions for Their Loved Ones
The overarching goal of the project is to improve the process and experience of surrogate decision-making by family caregivers. Since feeling unprepared to make surrogate decisions is a major contributor to caregiver stress, the…
- Conditions
- Neoplasms, Heart Failure, Kidney Diseases, Lung Diseases
- Trial name
- NCT02429479
- Testing
- Making Your Wishes Known, Standard advance care planning
- Where
- 2 sites in United States
- Volunteers
- 285 people
- Sponsor
- Milton S. Hershey Medical Center
Acute Respiratory Failure
Research on Respiratory Support Decision-Making for Mechanically Ventilated ICU Patients Based on a Physiological World Model
Mechanical ventilation is essential for ICU patients with respiratory failure, yet ventilator adjustment and weaning decisions remain experience-dependent and highly variable.
- Trial name
- NCT07834671
- Where
- China
- Volunteers
- 4,232 people
- Sponsor
- Ruijin Hospital
Diabetes Mellitus, Type 2
Scripps Digital Diabetes: Cloud-Based Continuous Glucose Monitoring (CB CGM)
Individuals with diabetes in the hospital often experience poor glycemic control, which places them at greater risk for infection, neurological and cardiac complications, mortality, longer lengths of stay, readmissions, and…
- Trial name
- NCT04269655
- Testing
- Cloud-Based Continuous Glucose Monitoring
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Scripps Whittier Diabetes Institute
Breast Cancer Screening
Trial of a Mammography Decision Aid for Women Aged 75 and Older
The aim of this study is to test whether an educational pamphlet on mammography designed for women aged 75 and older improves older women's decision-making around mammography screening.
- Trial name
- NCT02198690
- Testing
- Mammography decision aid, Home safety pamphlet
- Where
- 4 sites in United States
- Volunteers
- 541 people
- Sponsor
- Beth Israel Deaconess Medical Center
Labor, Induced, Patient Preference
Should I Have an Elective Induction?
The goal of the proposed study is to perform a pilot test of a patient-centered decision support tool to help pregnant people and providers work together in making informed, shared decisions regarding whether or not to opt for…
- Trial name
- SELECTION (NCT05838313)
- Testing
- Elective Induction of Labor Decision Support Tool
- Where
- 2 sites in United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Pregnancy Preterm, Premature Birth
The Periviable GOALS Decision Support Tool
The Periviable GOALS (Getting Optimal Alignment around Life Support) decision support tool (DST) is meant to facilitate informed shared decision-making regarding neonatal resuscitation for families facing the threat of a…
- Conditions
- Pregnancy Preterm, Premature Birth, Pregnancy Complications, Obstetric Labor, Premature
- Trial name
- NCT05264779
- Testing
- Periviable GOALS DST
- Where
- 12 sites in United States
- Volunteers
- 300 people
- Sponsor
- Indiana University
Asthma
Primary Care Implementation and Evaluation of Coach McLungs
The goal of this study is to evaluate the implementation of the Coach McLungsSM shared decision making (SDM) intervention into primary care across a large healthcare system.
- Trial name
- NCT05059210
- Testing
- Coach McLungs Intervention
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Wake Forest University Health Sciences
Heart Failure
Risk EValuation And Its Impact on ClinicAL Decision Making and Outcomes in Heart Failure
Heart failure is a complex and heterogenous disease with mortality and morbidity that equals more cancers. Numerous studies have examined the ability to improve prognostication from heart failure, ranging from basic statistical…
- Trial name
- REVeAL-HF (NCT03845660)
- Testing
- Electronic Alert
- Where
- United States
- Volunteers
- 3,124 people
- Sponsor
- Yale University