Clinical trials: Daily Disposable Soft Contact Lenses
Contact Lens
Evaluation of Wear Experience With a Daily Disposable Contact Lens
To evaluate the wear experience of current two-week contact lens wearers after they have been fit into a daily disposable contact lens. This is a single arm, non-comparative study.
- Trial name
- NCT04296877
- Testing
- Daily Disposable Contact Lens
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Myopia
Performance of DAILIES TOTAL1 Daily Disposable Contact Lenses in Habitual Soft Lens Wearers Who Report Substantial Digital Device Use
The purpose of this study is to evaluate the performance of DAILIES TOTAL1 daily disposable contact lenses with regards to subjective symptoms (comfort, dryness, vision) in lens wearers who use identify themselves as substantial…
- Trial name
- FOX (NCT06308666)
- Testing
- Delefilcon A contact lenses
- Where
- Canada
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Soft Contact Lenses, Myopia
DAILIES TOTAL1 Versus ACUVUE TruEye - Effects on the Biology of the Ocular Surface and Lid Margin
This is a prospective, single center, randomized, bilateral crossover, dispensing clinical trial to evaluate the effects of the water gradient lens, DAILIES TOTAL1, on the biology of corneal epithelium over two months of daily…
- Trial name
- TruEyeTotal1 (NCT02347631)
- Testing
- Soft Contact Lens - Daily Disposable Alcon Dailies Total 1 and ACUVUE TruEye, Soft Contact Lens - Acuvue TruEye and Alcon DAILIES TOTAL 1.
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Astigmatism Bilateral
Comparison of Two Daily Disposable Soft Contact Lenses
The aim of this study was to investigate the short-term clinical performance and subjective acceptance of the two study lenses.
- Trial name
- NCT03779503
- Testing
- midafilcon A, somofilcon A
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Presbyopia Condition
A Randomized, Active-Controlled, Double-Masked, Crossover Study to Evaluate the Clinical Performance of Deseyne (Vifilcon C) Daily Disposable Soft Contact Lens for Presbyopia Extended Depth of Focus (EDOF)
The goal of this clinical trial is to learn if the contact lens we are testing will work to extend the range of clear focus at distance to provide an increase in clear vision at closer ranges without the additional need for…
- Trial name
- EDOF (NCT06698731)
- Testing
- Test lens, Control lens
- Where
- 3 sites in United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Bruno Vision Care
Visual Acuity
A Comparison of Two Daily Disposable Soft Contact Lenses
Approximately 120 subjects will be comparing two soft contact lenses for one week each.
- Trial name
- NCT02427477
- Testing
- senofilcon A, delefilcon A
- Where
- 6 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Refractive Error - Myopia Bilateral
Study to Evaluate the Clinical Performance of Deseyne (Vifilcon C) Daily Disposable Soft Contact Lens
This clinical study is to provide clinical performance data comparing the test lens (Deseyne [vifilcon C] daily disposable soft contact lens) to a control lens (1-Day Acuvue Moist [etafilcon A] daily disposable soft contact lens)…
- Trial name
- NCT05927753
- Testing
- Deseyne Daily Disposable Contact Lens (Test Device)
- Where
- 3 sites in United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Bruno Vision Care
Refractive Errors
Clinical Assessment of a Daily Disposable Soft Silicone Hydrogel Contact Lens
The purpose of this study is to assess the clinical performance of DAILIES TOTAL1® spherical soft contact lenses over approximately 1 week of daily wear.
- Trial name
- NCT06044948
- Testing
- Delefilcon A contact lenses
- Where
- 6 sites in United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Contact Lens
Wear Experience With Daily Contact Lenses Over a Long Day
This study is evaluating the wear experience of a daily contact lens after 10, 12, 14, and 16 hours of lens wear.
- Trial name
- NCT04535310
- Testing
- Precision1® Daily Disposable Contact Lens
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Myopia
A Clinical Comparison of Three Soft Daily Disposable Contact Lenses
This study aims to compare the clinical performance of the somfilcon A, nelfilcon A II 2 and omafilcon A II 2 daily disposable contact lenses.
- Trial name
- NCT02920983
- Testing
- somofilcon A, nelfilcon A II 2, omafilcon A ll 2
- Where
- United Kingdom
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia, Myopia, Progressive
Myopia Progression With a Novel Extended Depth of Focus Contact Lens
Myopia has been increasing in prevalence and severity throughout the world over the last 30 years. Increasing levels of myopia are associated with increased frequencies and severity of various ocular pathologies, including…
- Trial name
- NCT03358862
- Testing
- NaturalVue Multifocal Contact Lens
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aller, Thomas A., OD
Myopia
Evaluation of the Performance of Different Daily Disposable Lens Designs in Habitual Soft Contact Lens Wearers
The main objective of the study is to refit existing soft lens wearers with two different daily disposable contact lens types, Lens A and Lens B, to determine their performance after one week of wear.
- Trial name
- NCT04668989
- Testing
- stenfilcon A - (Test lens), kalifilcon A - (Control Lens)
- Where
- 4 sites in United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Healthy, Healthy Participants
Do Daily Disposable Soft Contact Lenses Require Frequent Checks After the Initial Fitting is Complete in Adults Under 40 With No Contraindications
Patients who want to wear contact lenses often need to visit the optician multiple times. For example, they might go for an eye test, then return for the contact lens fitting, come back to pick up the lenses, and then again for…
- Trial name
- CLARIFI (NCT07370168)
- Where
- United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Aston University
Ocular Physiology
Clinical Evaluation of Delefilcon A and Verofilcon A Daily Disposable Toric Soft Contact Lenses Over One Week of Wear
This is a bilateral-wear, dispensing, randomized, controlled, double-masked, 2-sequence × 2-period crossover study to evaluate ocular physiology following contact lens wear.
- Trial name
- NCT05502289
- Testing
- TEST LENS, CONTROL LENS
- Where
- 6 sites in United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Astigmatism
Performance Evaluation of Two Daily Disposable Toric Lens Designs in Habitual Soft Contact Lens Wearers
The objective of the study is to compare the clinical performance of two different daily disposable, SiHy toric contact lens types, Lens A and Lens B, in existing soft lens wearers when worn for one week each.
- Trial name
- NCT04831515
- Testing
- Lens A, Lens B
- Where
- 4 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia, Soft Contact Lenses
A Clinical Trial Assessing the Efficacy and Safety of ST-1 Silicone Hydrogel Daily Disposable Soft Contact Lenses Compared to Miru 1day UpSide
This study will enroll 63 eligible subjects (126 eligible eyes, complete at least 108 evaluable eyes) in approximately 6 different medical centers in Taiwan, in order to evaluate the efficacy and safety of ST-1 silicone hydrogel…
- Conditions
- Myopia, Soft Contact Lenses, Daily Disposable Soft Contact Lenses
- Trial name
- NCT07345416
- Testing
- ST-1, Miru 1day UpSide
- Where
- 6 sites in Taiwan
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Menicon Co., Ltd.
Ocular Physiology
Evaluation of Delefilcon A and Senofilcon A Daily Disposable Toric Soft Contact Lenses Over Two Weeks of Wear
This will be a multi-site, bilateral, dispensing, randomized, controlled, double-masked, 2×2 crossover study to evaluate ocular physiological response.
- Trial name
- NCT06161012
- Testing
- Senofilcon A contact lenses (TEST), Delefilcon A contact lenses (CONTROL)
- Where
- 6 sites in United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Tear Film Hyperosmolarity
Tear Osmolarity Changes in Habitual Contact Lens Wearers
Tear osmolarity refers to the amount of osmotically active particles in tears and has been reported as one of the best diagnostic test for dry eye disease.
- Trial name
- NCT03531346
- Testing
- Daily-disposable soft contact lens
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Astigmatism
Evaluation of Delefilcon A and Senofilcon A Daily Disposable Toric Soft Contact Lenses Over One Week of Wear
This is a prospective, multi-site, 4-visit, bilateral, dispensing, randomized, controlled, double-masked, 2x2 crossover study to evaluate subjective comfort, overall opinion and end of day comfort following wear of two different…
- Trial name
- NCT06749496
- Testing
- Test Lens, Control Lens
- Where
- 12 sites in United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Ocular Physiology
Feasibility Evaluation of Daily Disposable Toric Soft Contact Lenses Manufactured With an Alternative Hydration Process
This is a bilateral wear, dispensing, randomized, controlled, double-masked, 2-sequence × 2-period crossover study to evaluate ocular physiology following approximately one week of contact lens wear.
- Trial name
- NCT05427539
- Testing
- TEST LENS, CONTROL LENS
- Where
- 6 sites in United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.