Clinical trials: Cutaneous Ulcer
Heel Pressure Ulceration Prevention Strategies
Evaluation of Heel Offloading Devices for Reducing Heel Contact Pressures in Healthy Volunteers
Prevention of heel pressure ulceration is a major clinical concern. Clinical research has shown that heel-offloading devices are effective at preventing heel ulceration when compared to no offloading or sub-optimal offloading…
- Trial name
- NCT02811965
- Testing
- Pillow Condition 1, Pillow Condition 2, Heel Foam Pillow
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- DeRoyal Industries, Inc.
Diabetic Foot Ulcer
Efficacy and Safety Study of Dermal-Living Skin Replacement to Treat Diabetic Foot Ulcers
The purpose of this study is to test the efficacy and side effects, if any, of Dermal - LSR combined with standard treatment. We hypothesize the treatment will provide beneficial results for diabetic patients suffering foot…
- Trial name
- NCT00368693
- Testing
- Dermal - Living Skin Replacement (Dermal-LSR)
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Varicose Ulcer
Vein Fitness System vs Compressive Therapy for Venous Ulcers: a Bayesian Adaptive Trial
The objective of this Bayesian Adaptive trial is to compare a control group versus a comprehensive ulcer healing protocol. The latter involves a combination of compressive therapy, miokinetic drainage and muscle strengthening for…
- Trial name
- NCT03127904
- Testing
- Vein Fitness, Compressive therapy and wound care
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Pró Circulação®
Varicose Ulcer, Veins Diseases
Treatment of Insufficient Superficial and Perforating Veins of the Lower Limb Using HIFU
This is a single-center prospective study with a planned accrual of 35 patients with diagnosed symptomatic Lower Limb Veins System (Superficial, Perforating) Insufficiency (including recurrence at the thigh/groin level after…
- Conditions
- Varicose Ulcer, Veins Diseases, Vein, Varicose
- Trial name
- Archimedes01 (NCT03304834)
- Testing
- ECHOPULSE
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Theraclion
Varicose Ulcer
Endovenous Ablation Combined With Fat Grafting for Venous Ulcers
The aim of this trial is to determine if fat grafting may have applicability to venous ulcers by comparing healing and recurrence rates in patients who receive combined fat grafting and endovenous ablation with patients who…
- Trial name
- NCT05241704
- Testing
- Fat grafting, Endovenous ablation of superficial venous reflux
- Where
- Ireland
- Volunteers
- 20 people
- Sponsor
- National University of Ireland, Galway, Ireland
Diabetic Foot, Amputation
Pattern and Type of Amputation and Mortality Rate Associated With Diabetic Foot in Jeddah, Saudi Arabia: A Retrospective Cohort Study
This study explored the pattern and type of amputations performed on patients with diabetic foot who were admitted to our institution, as well as the 7-year mortality rate of patients with diabetic foot at the same institution.
- Trial name
- NCT05123157
- Testing
- NO intervention
- Where
- Saudi Arabia
- Volunteers
- 358 people
- Sponsor
- King Abdulaziz University
Diabetic Foot Ulcer, Diabetic Foot
Effect of Self-foot Exercise on the Incidence of Plantar Foot Diabetic Ulcer Recurrence
The incidence of diabetic foot ulcer recurrence in one year can reach 35%. Plantar foot diabetic foot ulcer is the most frequently diabetic foot ulcer recurrence.
- Trial name
- NCT04624516
- Testing
- self-structured foot exercise
- Where
- Indonesia
- Volunteers
- 50 people
- Sponsor
- Maria Suryani
Pressure Ulcers
A Pilot Study of the Envision® Surface
This study is to evaluate the clinical safety and effectiveness of the Envision® surface.
- Trial name
- NCT00405834
- Testing
- Envision® Patient Support System
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Hill-Rom
Disability or Chronic Disease Leading to Disablement, Pressure Ulcer
Treatment of Osteomyelitis-associated Pressure Ulcers by Surgical Flaps and Anti-bacterial Agents
People with neuromotor disability (i.e. following an inborn or acquired spinal cord, cerebral or peripheral neurological lesion) are at high risk of osteomyelitis-associated pressure ulcers.
- Conditions
- Disability or Chronic Disease Leading to Disablement, Pressure Ulcer, Osteomyelitis
- Trial name
- NCT05713149
- Testing
- Surgical flap and anti-bacterial agents
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Institut de Sante Parasport Connecte Synergies
Diabetic Foot Ulcer
Trial of Herb Yuyang Ointment to Diabetic Foot Ulcer
The purpose of this study is to determine if dressing change with a kind of herb Yuyang ointment is clinically more efficacious and safer than Conventional treatment in the treatment of diabetic foot ulcers.
- Trial name
- NCT00839865
- Testing
- herb ointment
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Guiyang No.1 People's Hospital
Medical Device Site Erosion
Nursing Interventions on Prevention Medical Device Related Pressure Injury (MDRPI)
This study aims to assess the effect of implementing nursing interventions on preventing medical device related pressure injury in critically ill patients.
- Trial name
- MDRPI (NCT06513936)
- Testing
- The skin care Bundle, Routine care
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Damanhour University
Diabetic Foot Ulcer
A Prospective, Randomized, Double-Blind Multicenter Study Comparing CDO Therapy to Standard MWT in the Treatment of DFUs
The purpose of this study was to evaluate the safety and effectiveness of Continuous Diffusion of Oxygen (CDO) therapy for the treatment of Diabetic Foot Ulcers.
- Trial name
- NCT01645891
- Testing
- CDO electrochemical tissue oxygenation system, Moist Wound Therapy
- Where
- 33 sites in United States
- Volunteers
- 146 people
- Sponsor
- Electrochemical Oxygen Concepts, Inc.
Diabetic Foot Ulcer
Surgical Offloading Procedures for Diabetic Foot Ulcers
100 consenting subjects with Texas grade 1a diabetic foot ulcers will be randomized to surgical offloading or non-operative offloading.
- Trial name
- NCT03414216
- Testing
- Group 1 early offloading surgery, Group 2 - off-loading in fiberglass cast
- Volunteers
- 100 people
- Sponsor
- Assaf Harofeh MC
Pressure Injury, Transepidermal Water Loss
Effects of Patient-centered Skin Care in Critical Care
Many critical diseases can damage skin and tissue integrity due to natural immobility, hemodynamic instability, poor tissue perfusion, use of medical devices and many other internal and external factors.
- Conditions
- Pressure Injury, Transepidermal Water Loss, sk
- Trial name
- NCT05948306
- Testing
- Critical Patient-Centered Skin Care Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Istanbul Bilgi University
Pressure Injury, Nursing Caries
Mobile Application-Assisted Pressure Injury Management
Pressure injuries develop due to decreased movement, especially in bedridden individuals receiving home care. In Turkey, the management of pressure injuries is carried out by nurses in acute and long-term care settings, and…
- Conditions
- Pressure Injury, Nursing Caries, Application Site Wound
- Trial name
- NCT06848049
- Testing
- Mobile Aplication, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Fenerbahce University
Diabetic Foot
Effect of Photobiomodulation as a Preventive Treatment for Diabetic Foot
This study seeks to evaluate the effect of photobiomodulation (PBM) in the prevention of Diabetic foot (DF), in patients at moderate and high risk for its development, through a controlled, randomized, double-blind clinical…
- Trial name
- NCT06353568
- Testing
- Photobiomodulation, Simulation of Photobiomodulation, Therapeutic education
- Where
- Brazil
- Volunteers
- 64 people
- Sponsor
- University of Nove de Julho
Diabetic Foot
Diabetic Foot Ulcer Prevention System (DFUPS) - Part 2
The purpose of this study is to investigate whether regular measurement of skin foot temperature with a novel device (DFUPS) will prevent ulcer recurrence in diabetic patients at high risk of foot ulceration.
- Trial name
- DFUPS (NCT02579070)
- Testing
- DFUPS
- Where
- 3 sites in United Kingdom
- Volunteers
- 110 people
- Sponsor
- King's College Hospital NHS Trust
Diabetic Foot Ulcer
A Follow-up Study to Evaluate the Safety of ALLO-ASC-DFU in ALLO-ASC-DFU-101 Clinical Trial
This is an open-label follow up study to evaluate the safety for the subjects with ALLO-ASC-DFU treatment in phase 1 clinical trial (ALLO-ASC-DFU-101) for 23 months.
- Trial name
- NCT03183726
- Testing
- ALLO-ASC-DFU
- Volunteers
- 4 people
- Sponsor
- Anterogen Co., Ltd.
Diabetes, Diabetic Foot Ulcer
ExpressGraft-C9T1 Skin Tissue as a Treatment of Diabetic Foot Ulcers
This study is designed as a prospective, open-label trial focused on assessing the safety and tolerability of ExpressGraft-C9T1 skin tissue in the treatment of diabetic foot ulcers (DFU).
- Conditions
- Diabetes, Diabetic Foot Ulcer, Non-healing Wound
- Trial name
- NCT02657876
- Testing
- ExpressGraft-C9T1 Skin Tissue
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Stratatech, a Mallinckrodt Company
Debridement Care, Leg Ulcer
Effectiveness of Musicotherapy in Reducing Pain Induced by Leg Ulcer Care
Venous leg ulcer is the final stage of chronic venous disease and only develops due to advanced chronic venous insufficiency. The problems caused by venous disease are initially minor and often neglected, but can impact the…
- Conditions
- Debridement Care, Leg Ulcer, Leg Ulcers Venous, Pain
- Trial name
- MUS-ICAT (NCT06153589)
- Testing
- Musicotherapy
- Where
- France
- Volunteers
- 180 people
- Sponsor
- University Hospital Center of Martinique