Clinical trials: Curcumin
Wrinkle Appearance, Skin Pigment
Cosmetic Effects of Topical Acetyl Zingerone
Cosmeceuticals are an emerging market within dermatology and the growth of natural products and derivatives of natural products has accelerated in use within the field.
- Conditions
- Wrinkle Appearance, Skin Pigment, Erythema, Side Effect
- Trial name
- NCT03530787
- Testing
- Acetyl Zingerone Topical Cream, Topical cream
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Chronic Periodontitis
Clinical and Anti-inflammatory Effect of Curcumin Oral Gel as Adjuncts in Treatment of Periodontal Pocket
application of 1% curcumin gel in clinical study design will be used . The study will be conducted in Al-Najaf specialised dentistry center.
- Trial name
- NCT04355416
- Testing
- curcumin Oral gel, subgingival scaling and root planing
- Where
- Iraq
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Inflammation, Knee Pain Chronic
Effects of UC-II, Glucosamine and Curcumin Supplementation on Knee Pain and Inflammation.
This research evaluated the effects of UCII, glucosamine and curcumin supplementation on knee pain and inflammation.
- Trial name
- NCT06581094
- Testing
- UCII, glucosamine and curcumin
- Where
- Taiwan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Uterine Cervical Dysplasia
Trial on Safety and Pharmacokinetics of Intravaginal Curcumin
The main objective of this study is to determine the maximum tolerable dose and safety of intravaginal curcumin in a normal population of women (women with no evidence of cervical cytological abnormalities by pap testing).
- Trial name
- NCT01035580
- Testing
- Curcumin
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Emory University
Healthy
Photodynamic Therapy (PDT) for Oral Disinfection
Photodynamic therapy (PDT) is a technique used for the oral disinfection. In dentistry, PDT for microbial inactivation may reduces both dental plaque and risk of developing caries as well as contributes to treat gingivitis…
- Trial name
- NCT02152475
- Testing
- mouthwash with curcumin, blue LED illumination
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Effect of Resveratrol and Curcumin on Inflammation
Effect of Antioxidant Intake on Cardiovascular Risk
The general objective of this project is to investigate the acute effect of consuming a dietary supplement combining resveratrol and curcumin on the inflammatory response following the consumption of a high-fat meal in healthy…
- Trial name
- NCT01964846
- Testing
- Resveratrol, curcumin
- Where
- Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Laval University
Periodontitis
Curcumin-Simvastatin-EDTA in the Treatment of Periodontitis
Among the root conditioning materials is the Ethylenediaminetetraacetic acid (EDTA). EDTA exposes the collagen fibers on dentin surfaces and also enhances early cell colonization.
- Trial name
- NCT04044417
- Testing
- currettage, curcumin simvastatin paste, EDTA root conditioning
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Healthy Participants
Pilot Assessment of the Safety of a Combination of Curcumin, Omega-3, and Vitamin D Supplements
Curcumin, Omega-3 and Vitamin-D (COD) are commonly used dietary supplements, which are licensed natural health products in Canada.
- Trial name
- PASCOD (NCT05414838)
- Testing
- Curcumin, Omega-3 and Vitamin-D (COD)
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Positivity for Helicobacter Pylori
The Impact of Addition of Curcumin for 10 Days Triple Therapy, on the Eradication Rate of Helicobacter Pylori Infection
Background and Aims H.pylori is a common human pathogen by which almost 50% of the world population is infected. According to the accepted guidelines, once H.pylori infection has been diagnosed,first line therapy with three drugs…
- Trial name
- CurHP (NCT02018328)
- Testing
- Curcumin
- Where
- 2 sites in Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Gingold Belfer Rachel
Oral Ulcer, Orthodontic Appliances, Fixed
Effectiveness of a Curcumin Mouthwash in Preventing Traumatic Ulcers in Patients With Fixed Orthodontic Appliances
The study is a randomized controlled trial. The participants will be equally allocated into 2 groups to compare clinical effectiveness of curcumin mouthwash in fixed orthodontic patients during the first month of treatment.
- Trial name
- NCT05147376
- Testing
- Curcumin mouthwash
- Where
- Thailand
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Optic Atrophy, Hereditary, Leber
A Randomized, Double-blind, Placebo-controlled Trial of Curcumin in Leber's Hereditary Optic Neuropathy (LHON)
Background Leber's Hereditary Optic Neuropathy (LHON) is a maternally inherited ocular disorder associated with a mutation in mtDNA .
- Trial name
- NCT00528151
- Testing
- curcumin
- Where
- Thailand
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Bioavailability
Enhanced Absorption of curQ+ or Liposomal Curcumin Formulations Versus 95% Curcumin Powder in Healthy Subjects
This study is intended to evaluate how significantly a proprietary curcumin formulation (curQ+® or liposomal curcumin) results in greater GI absorption compared to 95% curcumin extract over a 6-hour time period following a single…
- Trial name
- NCT06177483
- Testing
- 95% curcumin extract powder, curQ+ curcumin formulation, liposomal curcumin formulation
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- ESM Technologies, LLC
Typhoid Carrier, Typhoid Fever
Curcumin Extract Added to Ciprofloxacin for Typhoid Carriers Among Food Handlers of the Free Nutritious Meal Program
Some people keep carrying Salmonella Typhi after they recover from typhoid fever. These carriers have no symptoms. They can still pass the bacteria into food.
- Conditions
- Typhoid Carrier, Typhoid Fever, Salmonella Typhi Infection
- Trial name
- NCT07908030
- Testing
- Curcumin extract, Ciprofloxacin
- Where
- Indonesia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universitas Sebelas Maret
Inflammation, Atherosclerosis
Effects of Short-term Curcumin and Multi-polyphenol Supplementation on the Anti-inflammatory Properties of HDL
Polyphenol supplements, including curcumin and resveratrol, are known to decrease inflammation, but previous polyphenol supplements were poorly absorbed and thus their effects were reduced.
- Conditions
- Inflammation, Atherosclerosis, Cardiovascular Disease
- Trial name
- PSI (NCT02998918)
- Testing
- PolyResveratrol Supplementation, Curcumin Supplementation
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Periodontitis
Efficacy of Curcumin Gel Combined With Non-surgical Periodontal Therapy on Salivary Procalcitonin Level in the Treatment of Periodontitis Patients
Objectives: To evaluate the efficacy of curcumin gel as an adjunct to scaling and root planing (SRP) on the salivary procalcitonin level in the treatment of periodontitis.
- Trial name
- NCT05667376
- Testing
- Local drug delivery, curcumin gel
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Reham abdelfatah
Memory, Cognitive Function Decline
Cognitive Effects of Bioavailable Curcumin
An estimated 50% of older adults complain of memory changes that worsen as they age. Although numerous commercially available dietary supplements claim cognitive benefits, relatively few well-designed, longitudinal…
- Trial name
- NCT07251985
- Testing
- Curcumin
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Diabetes
Effects of Curcumin on Postprandial Blood Glucose, and Insulin in Healthy Subjects
Previous animal studies have shown that extracts of Curcumin lowers blood glucose.
- Trial name
- NCT01029327
- Where
- Sweden
- Volunteers
- healthy volunteers welcome
- Sponsor
- Skane University Hospital
Pharmacokinetics of Novel Curcumin Formulations, Safety of Novel Curcumin Formulations
Oral Bioavailability of Curcumin From Micronized Powder and Liquid Micelles in Healthy Young Women and Men
Background: The oral bioavailability of curcumin is low due to its limited intestinal uptake, rapid metabolism and excretion from the body.
- Trial name
- NCT01925287
- Testing
- curcumin
- Where
- Germany
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Hohenheim
Wound Healing, Alveolitis of Jaw
Effect of Curcumin Topical Spray on Wound Healing After Tooth Extraction
This randomized, single-blind, controlled clinical trial aims to evaluate the effects of a topical curcumin spray on post-extraction wound healing and postoperative symptoms in adults undergoing first molar extraction.
- Conditions
- Wound Healing, Alveolitis of Jaw, Tooth Extraction, Curcumin
- Trial name
- NCT07874789
- Testing
- Curcumin Topical Spray, Chlorhexidine Topical Spray
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Oral Submucous Fibrosis
Topical Application of Curcumin Orabase in Oral Submucous Fibrosis (OSMF)
Curcumin (diferuloylmethane) is the chief component of the spice turmeric and is derived from the rhizome of the East Indian plant Curcuma longa.
- Trial name
- NCT02645656
- Testing
- Curcumin Arm
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- SVS Institute of Dental Sciences