Clinical trials: Cryotherapy Effect
Breast Cancer Female
Chemotherapy - Induced Peripheral Neuropathy
The purpose of this study was to examine the efficacy of cryotherapy with frozen gloves for the prevention of the chemotherapy-induced peripheral neuropathy (CIPN) of the hand.
- Trial name
- NCT05138042
- Testing
- Cryotherapy (frozen glove)
- Where
- Taiwan
- Volunteers
- 22 people
- Sponsor
- Chung Shan Medical University
Peripheral Intravenous Phlebitis, Injection Site Pain
Ice Application for Oxacillin-Related Phlebitis and Pain
This randomized controlled trial evaluated whether ice application could reduce pain and peripheral intravenous phlebitis associated with oxacillin administration.
- Conditions
- Peripheral Intravenous Phlebitis, Injection Site Pain, Pain
- Trial name
- NCT07820956
- Testing
- Ice Application, Room-Temperature Water-Bag Application
- Where
- Taiwan
- Volunteers
- 86 people
- Sponsor
- Central Taiwan University of Science and Technology
Muscle Strength
Cold and Isometric Strength
Cryotherapy has a wide range of clinical applications in rehabilitation, used for activities such as controlling inflammation, pain control or management of edema after an injury or surgery.
- Trial name
- NCT02884193
- Testing
- Brief Cooling, Prolonged Cold
- Where
- Chile
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Quiropraxia y Equilibrio
Atrial Fibrillation
A Time-to-effect Based Dosing Strategy in Cryoballoon Ablation of Patients With Paroxysmal Atrial Fibrillation
This study aims to validate a new dosage of cryotherapy based on time to effect in pulmonary vein ablation procedures in patients with paroxysmal atrial fibrillation.
- Trial name
- plusONE (NCT02789358)
- Testing
- Conventional cryotherapy dosage, Experimental cryotherapy dosage, Arctic Front Advance ST Cryoenergy Balloon Catheter
- Where
- Spain
- Volunteers
- 140 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Lung Neoplasms, Airway Obstruction
RejuvenAir™ System Lobectomy Safety and Histology Study
Cryotherapy has a long history of safe use in various medical procedures. RejuvenAir System radial spray cryotherapy is a novel procedure being developed as a treatment for conditions associated with abnormal bronchial function…
- Conditions
- Lung Neoplasms, Airway Obstruction, Lung Cancer
- Trial name
- Lobectomy (NCT02106143)
- Testing
- RejuvenAir™ Radial Spray Cryotherapy
- Where
- 3 sites in Ireland, Netherlands and 1 more
- Volunteers
- 11 people
- Sponsor
- CSA Medical, Inc.
Cryotherapy Effect
Cryoanalgesia for Arterial Puncture Pain
Arterial puncture is a painful procedure performed to assess patients' acid-base and respiratory status. Pain is a stressful situation for unconscious patients as they cannot communicate their feeling verbally.
- Trial name
- NCT05251688
- Testing
- Cryoanalgesia
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Mansoura University
Dental Pulp Necrosis
Pain and Microbial Reduction of Antimicrobial Corticosteroid Mixture Versus Cryotherapy in Necrotic Teeth
The aim of this study is to compare the effect of antimicrobial-corticosteroid mixture and cryotherapy as final root canal irrigating solutions on post-instrumentation pain in single-canal teeth with necrotic pulps.
- Trial name
- MIXCRYO (NCT05739682)
- Testing
- Local anaesthetic injection of 4% articaine with 1:100000 epinephrine, Tooth isolation, Access cavity preparation
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Cairo University
Pain, Postoperative, Hysterectomy
Abdominal Ice Packs for Pain Control and Reduction of Narcotic Use Following Laparoscopic Hysterectomy
The purpose of this study is to evaluate the effect of using ice packs on the abdomen immediately after laparoscopic hysterectomy surgery on pain control and narcotic pain medication use.
- Conditions
- Pain, Postoperative, Hysterectomy, Narcotic Use, Cryotherapy Effect
- Trial name
- NCT03341533
- Testing
- Ice packs plus usual post-op analgesia, Usual post-op analgesia
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- Mayo Clinic
Dysmenorrhea Primary
Effect of Cryotherapy on Primary Dysmenorrhoea
Dysmenorrhea is a menstrual disorder defined by the presence of painful cramps of uterine origin that occur during menstruation.
- Trial name
- NCT06320145
- Testing
- Cryotherapy, core stability exercises
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Granuloma, Pyogenic, Cryotherapy Effect
Evaluation of Cryotherapy in Granuloma Pyogenicum
Surgical excision needs general anesthesia and might have complications due to anesthesia. Cryotherapy can be used in an outpatient setting and doesn't need general anesthesia.
- Trial name
- NCT05692427
- Testing
- Cryopen - Cryotherapy
- Where
- Austria
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Cancer, Pleural Neoplasms
Safety, Efficacy, and Side Effects Study of Interventional Cryotherapy in the Pleural Space("ICE PLS")
The purpose of this study is to evaluate the safety, efficacy, and side effects of the CryoSpray Ablation(TM) System (CSA(TM) System) to treat neoplastic lesions on the parietal pleural surface.
- Trial name
- NCT00747916
- Testing
- CryoSpray Ablation (TM) System
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- CSA Medical, Inc.
Post-endodontic Pain
Effect of Submucosal Cryotherapy on Postoperative Endodontic Pain
The goal of this clinical trial is to compare submucosal Cryotherapy with different anti-inflammatory drugs in the reduction of post-endodontic pain in upper premolars with symptomatic irreversible pulpitis.
- Trial name
- NCT06090500
- Testing
- Cryotherapy, Diclofenac sodium, Dexamethasone sodium phosphate
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
MIH, Molar-Incisor Hypomineralization
Effects of Silver Diamine Fluoride and Intraoral Cryotherapy on Local Anesthesia in MIH-Affected Molars
Molar-incisor hypomineralization (MIH) is a developmental enamel defect of unclear etiology that affects permanent first molars and often permanent incisors, leading to increased porosity, hypersensitivity, and poor prognosis.
- Conditions
- MIH, Molar-Incisor Hypomineralization, Caries Assessment
- Trial name
- NCT07326241
- Testing
- Standard Local Anesthesia, Intraoral Cryotherapy, Silver Diamine Fluoride (SDF)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Root Canal Treatment, Intra-operative Pain
This Clinical Trial Aims to Compare the Effectiveness of Two Intra-pulpal Cryotherapy Techniques-Endo-ice and Ice Sticks-in Decreasing Intra-operative Pain and Enhancing the Success of Local Anesthesia During Pulpectomy of Mandibular Molars With Symptomatic Irreversible Pulpitis.
The goal of this clinical trail is to compare the analgesic effect of endo-ice and ice-sticks in reducing intra-operative pain during pulpectomy in molars with Symptomatic Irreversible Pulpitis.
- Conditions
- Root Canal Treatment, Intra-operative Pain, Symptomatic Irreversible Pulpitis, Cryotherapy Effect
- Trial name
- NCT07264829
- Testing
- Endo-ice (Refrigerant Spray), Ice-sticks
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Dow University of Health Sciences
Functional Status, Muscle Tone
Effects of Cryotherapy on Ankle Function
The ankle joint is commonly used and also stricken by high loads and injuries in sports. One technique in emphasis is cryotherapy, a physiotherapeutical intervention characterized by the use of low temperatures for tissue…
- Trial name
- NCT05331092
- Testing
- Cryotherapy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- São Paulo State University
Symptomatic Irreversible Pulpitis and Post Operative Pain
Ultrasonic Activated Irrigation and Intracanal Cryotherapy for Reducing Pain After Root Canal Treatment
This randomized controlled trial aims to evaluate the effect of ultrasonic activated irrigation with and without intracanal cryotherapy on postoperative pain following single-visit root canal treatment in teeth with symptomatic…
- Trial name
- NCT07663227
- Testing
- Ultrasonic Activated Irrigation, Intracanal cryotherapy
- Volunteers
- 60 people
- Sponsor
- Dr Arsalan Ali Khan
Cancer
Cryotherapy for Neuropathy in Children
This study aimed to assess the efficacy of cryotherapy in controlling Peripheral Neuropathy in cancer children
- Trial name
- NCT04536207
- Testing
- Cryotherapy (apparatus)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- South Valley University
Myeloma, Mucositis
Cryotherapy Against Oral Mucositis After High-dose Melphalan
In this prospective, randomised, controlled, open-label, Phase III, non-inferiority clinical trial trial patients with a diagnosis of myeloma who were undergoing autologous HSCT were randomised 1:1 to receive cryotherapy for 7…
- Conditions
- Myeloma, Mucositis, Cryotherapy Effect
- Trial name
- NCT03704597
- Testing
- cryotherapy
- Volunteers
- 100 people
- Sponsor
- Sahlgrenska University Hospital
Postoperative Pain After Cesarean Section, Postoperative Pain
Abdominal Ice Application After Cesarean Section
Cesarean section is one of the most commonly performed surgical procedures worldwide, and effective postoperative pain control is important for maternal recovery and patient comfort.
- Conditions
- Postoperative Pain After Cesarean Section, Postoperative Pain, Cesarean Section
- Trial name
- ICE-CS (NCT07626138)
- Testing
- Abdominal Ice Application, Standard Postoperative Care
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Nigde Omer Halisdemir University
Muscle Soreness
Neuromuscular Responses to Recovery Techniques
Cold water immersion (CWI) and percussive massage therapy (PMT) are commonly used re-covery techniques in team sports. In particular, despite its wide use, PMT has been scarcely investigated in the literature, especially…
- Trial name
- NCT06433856
- Testing
- Cold Water Immersion, Percussive Massage Therapy
- Where
- Italy
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Trieste