Clinical trials: Cryotherapy
Solar Lentigines
A Fixed Triple Combination Cream for Solar Lentigines Associated to Cryotherapy
To evaluate safety and efficacy of Tri-Luma® cream as an adjunctive treatment to cryotherapy when used in the pre- and post-procedure phases for the treatment of solar lentigines on the back of the hands and in the prevention of…
- Trial name
- NCT01778179
- Testing
- Tri-luma, Cryotherapy (CRY-AC3® device)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hexsel Dermatology Clinic
Basal Cell Carcinoma (BCC)
Intralesional Cryosurgery for Basal Cell Carcinoma - a Feasibility Study
A feasibility study for the treatment of Basal Cell Carcinoma of the lower extremities in the elderly utilizing intralesional cryosurgery.
- Trial name
- NCT01633515
- Testing
- Intralesional cryotherapy
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Carmel Medical Center
Warts
Clinical Study : Efficacy and Safety of Three Cryotherapy Devices for Wart Treatment
The present study was set-up to evaluate clinical efficacy of Pixie® cryogenic pen versus two comparator cryogenic products (Wartner® and Wortie®) for the treatment of common and plantar warts.
- Trial name
- NCT03129373
- Testing
- Cryogenic treatment of warts
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Oystershell NV
Hemorrhoid, Hemorrhoidectomy
Cryotherapy for Post-Hemorrhoidectomy Pain
This prospective, patient-blinded randomized controlled trial will be conducted at Kasr Al-Ainy Hospital, Cairo University. Adult patients with grade III or IV hemorrhoids undergoing elective surgery will be randomized (1:1) to…
- Trial name
- NCT07714122
- Testing
- Milligan-Morgan Hemorrhoidectomy with Cryotherapy, Miligan-Morgan haemorroidectomy
- Where
- Egypt
- Volunteers
- 114 people
- Sponsor
- Cairo University
Post-operative Pain
Reduction of Post-endodontic Pain After 3 Irrigation Regime
The goal of this research was to relate the occurrence of post-endodontic pain after single-visit RCT using there irrigating regime.
- Trial name
- RPEP (NCT03559140)
- Testing
- Applied saline solution at 2.5 oC (Cryotherapy group), Applied saline solution at 8oC (Cryotherapy ), Applied saline solution at room temperature (No cryotherapy)
- Where
- Mexico
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Barrett's Esophagus, Esophageal Cancer
CryoSpray Ablation (TM) GI Patient Registry
The purpose of this study is to create a patient registry to collect and analyze post-510K approval information on subjects treated endoscopically with the CryoSpray Ablation™ System.
- Trial name
- NCT00747448
- Where
- 6 sites in United States
- Volunteers
- 199 people
- Sponsor
- CSA Medical, Inc.
Symptomatic Periapical Periodontitis
Influence of Intra-Canal Cryotherapy on Post-Endodontic Pain and Interleukin-6 Expression Using Different Irrigation Protocols: A Randomized Clinical Trial
the study was to evaluate the effect of intra-canal cryotherapy on post-endodontic pain and interleukin-6 expression in teeth with symptomatic apical periodontitis using different irrigation protocols.
- Trial name
- NCT04324398
- Testing
- Cryotherapy
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Solar Lentigo, Senile Lentigo
Tolerance and Performance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots.
CS5_3 aims to evaluate the tolerance and to adjust the mode of administration of 4 different conditions of cryotherapy treatments applied on the brown spots of the face and hands with 3 prototypes.
- Conditions
- Solar Lentigo, Senile Lentigo, Post-inflammatory Hyperpigmentation
- Trial name
- NCT05625815
- Testing
- Prototypes (816-v1 001) to (816-v1 050), Prototype (816-v1 051) to (816-v1 100), Prototypes (816-v1 101) to (816-v1 150)
- Where
- South Africa
- Volunteers
- 32 people
- Sponsor
- Cryonove Pharma
Soft Tissue Sarcoma
Ipilimumab + Nivolumab + Cryotherapy in Metastatic or Locally Advanced Soft Tissue Sarcoma
The purpose of this Phase 2 study is to 1. find out if the study drugs (ipilimumab plus nivolumab) in combination with cryotherapy will help participants with metastatic or locally advanced soft tissue sarcoma;. 2.
- Trial name
- NCT04118166
- Testing
- Ipilimumab, Cryoablation, Nivolumab
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Kristen Ganjoo
Muscle Fatigue (C23.888.592.612.612), Athletic Injuries (C26.857.500.124)
Recovery Optimization Intervention to Reduce the Risk of Injuries in Soccer Players
The goal of this clinical trial is to evaluate if recovery interventions using cold and hot water immersion can reduce the risk of injuries in amateur soccer players.
- Conditions
- Muscle Fatigue (C23.888.592.612.612), Athletic Injuries (C26.857.500.124), Recovery of Function (G11.427.698.620), Cryotherapy (E02.095.301.250)
- Trial name
- NCT06920966
- Testing
- Cold Water Immersion (CWI), Hot water immersion (HWI), Thermography-Guided Immersion (TI)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Chronic Low Back Pain
Influence of Cryotherapy Combined to TENS Burst in Patients With Non-specific Chronic Lombar Pain
The purpose of this study is to analyze the effects of TENS Burst combined Cryotherapy on painful sensation, functional capacity and quality of life of patients with non-specific chronic pain.
- Trial name
- NCT03111199
- Testing
- Cryotherpy, TENS Burst, Education
- Where
- Brazil
- Volunteers
- 48 people
- Sponsor
- Wouber Hérickson de Brito Vieira
Postoperative Pain, Vital Pulp Therapies
Impact of Sodium Hypochlorite Irrigation at Different Concentrations, With and Without Cryotherapy, on Post Operative Pain in Permanent Mandibular Molar Teeth.
The aim of the present study will compare the impact of sodium hypochlorite irrigation at different concentrations with and without cryotherapy on post operative pain in permanent mandibular molar teeth.
- Trial name
- VPT-RCT-MTA (NCT07771816)
- Testing
- vital pulp therapy
- Where
- Egypt
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Progression of Prostate Cancer
FOcal RECurrent Assessment and Salvage Treatment
Radiotherapy is the commonest form of prostate cancer treatment in the UK. In one in four men, radiotherapy will fail to control the cancer. These men are offered hormonal treatment which has significant side effects.
- Trial name
- FORECAST (NCT01883128)
- Testing
- Whole Body MRI, Focal Salvage Therapy, MRI Targeted biopsies
- Where
- 2 sites in United Kingdom
- Volunteers
- 177 people
- Sponsor
- University College London Hospitals
Cryotherapy Effect, Warts
Cost-effectiveness of EndWarts® FREEZE - an Alternative Home Cryotherapy Device for Wart Treatment
This study aimed to study cost-effectiveness of EndWarts® FREEZE for wart treatment, compared to conventional liquid nitrogen cryotherapy
- Trial name
- NCT04781244
- Testing
- EndWarts® FREEZE, Liquid nitrogen
- Where
- Thailand
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Post-exercise Muscle Recovery
Phototherapy and Cryotherapy in Post-exercise Skeletal Muscle Recovery
Volunteers were divided randomly in five experimental groups. VAS (Visual Analogic scale) to measure DOMS (Delayed Onset Muscle Soreness) and blood samples was taken before any procedure.
- Trial name
- NCT02622971
- Testing
- PBMT, Cryotherapy
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Late Postvitrectomy Diabetic Hemorrhage.
Cryotherapy of Sclerotomy Sites for Prevention of Late Postvitrectomy Diabetic Hemorrhage
Late vitreous hemorrhage in postvitrectomized diabetic eyes may be due to fibrovascular tuft formation in sclerotomy sites. Cryotherapy of sclerotomy sites may prevent bleeding by regressing the fibrovascular tuft.
- Trial name
- NCT00370409
- Testing
- Cryotherapy
- Where
- Iran
- Volunteers
- 112 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Prostate, Prostate Cancer
Focal Therapy in Localized Prostate Cancer: a Prospective Registry
The principal aim of the registry is to collect data on focal therapy (FT) for the treatment of intermediate-risk prostate cancer across Europe.
- Trial name
- JR (NCT06772116)
- Testing
- Focal Therapy
- Volunteers
- 1,000 people
- Sponsor
- Institut Mutualiste Montsouris
Cutaneous Warts
Evaluation of the Efficacy of Cryotherapy Combined With Intralesional Hepatitis B Virus Vaccine Versus Either Therapy in the Treatment of Multiple Cutaneous Warts :a Comparative Study
1. investigate the efficacy and safety of combined cryotherapy with intralesional HBV vaccine injection in the treatment of multiple common warts. 2.
- Trial name
- NCT05902624
- Testing
- Hepatitis B Virus Vaccine(HBV)
- Volunteers
- 60 people
- Sponsor
- Assiut University
Prostate Cancer
Prostate Conformal Cryotherapy
The goal of this clinical research study is to learn if using cryotherapy to treat only the part of the prostate that contains cancer is an effective treatment for prostate cancer.
- Trial name
- NCT00877682
- Testing
- Cryoablation
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- M.D. Anderson Cancer Center
NSCLC, Cryotherapy
Post-Market Registry of Transbronchial Cryo-assisted RFA During Routine Standard Bronchoscopic Tumor Stagng and Resection
In order to secure the diagnosis of lung cancer, the investigator will perform a bronchoscopy in order to take tissue samples. These samples will be analyzed in the pathology. This is the routine standard.
- Conditions
- NSCLC, Cryotherapy, RFA
- Trial name
- Cronos (NCT07530744)
- Testing
- Cryotherapy
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- Elisabethinen Hospital