Clinical trials: CryoAblation
Atrial Fibrillation
Patient-reported Outcome Follow-up Based on the Northern Shanghai Community Chronic Disease Management System
Influence of patient-reported outcome follow-up based on the northern Shanghai community chronic disease management system on the follow-up compliance and satisfaction of patients with atrial fibrillation after cryoablation.
- Trial name
- NCT05511662
- Testing
- PRO follow up
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Shanghai 10th People's Hospital
Atrial Fibrillation
Safety and Efficacy of CryoCor™ Cryoablation for PAF
A multi-center, randomized, controlled study of cryoablation vs medical management for the treatment of PAF
- Trial name
- NCT00231296
- Testing
- Cardiac CryoCor Cryoablation System, Medical management
- Where
- 24 sites in United States
- Volunteers
- 174 people
- Sponsor
- Boston Scientific Corporation
Benign Thyroid Nodule
Cryoablation of Benign Thyroid Nodules: a Pilot Study
This study will evaluate the clinical response and safety of ultrasound guided percutaneous cryoablation in the treatment of benign thyroid nodules as an alternative to the surgery.
- Trial name
- NCT06014229
- Testing
- cryoablation
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- University of Sao Paulo General Hospital
Breast Cancer
Cryoablation for Invasive Breast Carcinoma Following Neoadjuvant Therapy
Cryoablation is a procedure that uses a hollow, thin tube called a cryoprobe to freeze and destroy cancer tissue. The goal of this clinical research study is to learn about the level of effectiveness of using ultrasound-guided…
- Trial name
- NCT01388777
- Testing
- Visica 2™ Treatment System, Cryoablation, Surgical Resection
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- M.D. Anderson Cancer Center
Prostate Cancer
Feasibility Study of Prostate Tumor Localization for Focal Cryoablation of Prostate Carcinoma
The purpose of the present study is to find out if MRI techniques examining (1) the motion of water molecules in the prostate (diffusion sensitive MRI), (2) the difference in blood flow to the prostate (dynamic contrast enhanced…
- Trial name
- NCT00851682
- Testing
- MRI scan
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Washington University School of Medicine
Lung Adenocarcinoma, Cryotherapy Effect
Cryoablation in Combination (or Not) With Pembrolizumab and Pemetrexed-carboplatin in 1st-line Treatment for Patients With Metastatic Lung Adenocarcinoma
This study aims to compare the one-year survival benefit of the association of cryoablation-pembrolizumab-pemetrexed-carboplatin versus pembrolizumab-pemetrexed-carboplatin in metastatic lung adenocarcinoma patients.
- Trial name
- CRYOMUNE (NCT04339218)
- Testing
- Cryoablation, Pembrolizumab, Pemetrexed
- Where
- France
- Volunteers
- 214 people
- Sponsor
- Institut Bergonié
Paroxysmal Atrial Fibrillation
The OneFreeze Study
The One Freeze study is a prospective multi-center randomized controlled trial to assess the safety and efficacy of one vs. two cryoablations per pulmonary vein for the treatment of atrial fibrillation.
- Trial name
- OneFreeze (NCT02217254)
- Testing
- Atrial fibrillation catheter ablation using the Medtronic Arctic Front Ablation System
- Where
- 3 sites in United States, Canada
- Volunteers
- 90 people
- Sponsor
- University of California, San Francisco
Renal Cell Cancer
Percutaneous Tumor Ablation Vs Partial Nephrectomy for Small Renal Mass: the Impact of Histologic Variant and Tumor Size
The aim, of this study is to investigate recurrence rates in patients with T1 renal cell carcinoma (RCC) undergone partial nephrectomy (PN), radiofrequency ablation (RFA) or cryoablation (Cryo).
- Trial name
- CRYO-BO-2021 (NCT06829888)
- Volunteers
- 955 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Therapy, Soft Tissue Lesion
Infant and Child European Cryoablation Project ICECaP
A registry to audit the current range of applications, technical success rate, safety profile, complication rate and efficacy of cryoablation procedures being performed in children.
- Conditions
- Therapy, Soft Tissue Lesion, Cryoablation, Pediatric
- Trial name
- NCT03721783
- Testing
- Cryoablation
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Breast Cancer, Breast Neoplasm
CRYoablation for Small Tumors As Local Treatment - SIX Trial
To demonstrate the non-inferiority of cryoablation compared to breast surgery for the local treatment of early-stage breast cancer and to conduct a cost-minimization analysis comparing direct costs between treatments.
- Trial name
- CRYSTAL - SIX (NCT06839001)
- Testing
- cryoablation, Breast Surgery (Lumpectomy or Mastectomy)
- Where
- 2 sites in Brazil
- Volunteers
- 750 people
- Sponsor
- Hospital do Coracao
Breast Cancer
Cryoablation Therapy in Treating Patients With Invasive Ductal Breast Cancer
This phase II trial is studying how well cryoablation therapy works in treating patients with invasive ductal breast cancer. Cryoablation kills tumor cells by freezing them.
- Trial name
- NCT00723294
- Testing
- cryosurgery, therapeutic conventional surgery
- Where
- 16 sites in United States
- Volunteers
- 99 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Metastatic Cancer
In-Situ Therapeutic Cancer Vaccine for Metastatic Cancer Combining AlloStim With Tumor Cryoablation
This is a Phase I/II study to investigate the feasibility of creating a personalized therapeutic cancer vaccine within the body. A vaccine contains a source of tumor antigen and an adjuvant.
- Trial name
- NCT00861107
- Testing
- AlloStim-7, percutaneous tumor cryoablation, AlloStim8 or AlloStim-9
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mirror Biologics, Inc.
Prostate Cancer
Targeted Cryoablation of Prostate Cancer Lesions: An Investigator-initiated Trial
This clinical trial is to provide a minimally invasive treatment option in which the targeted prostate cancer tissue is killed by cryoablation at extremely low temperatures only in the specific area of cancer "that should be…
- Trial name
- PROCRY (NCT05500846)
- Testing
- The Visual Ice Cryoablation System
- Where
- 2 sites in Japan
- Volunteers
- 51 people
- Sponsor
- Osamu Ukimura
Prostate Cancer
Cryotherapy With or Without Short-term Adjuvant Androgen-Deprivation Therapy in Prostate Cancer
This is an open-label randomized clinical study comparing primary prostate cryoablation alone (No-ADT group) with cryoablation plus short-term adjuvant androgen-deprivation therapy (Adj-ADT group) in the treatment of patients…
- Trial name
- NCT01398657
- Testing
- Adjuvant Androgen-Deprivation Therapy
- Where
- Taiwan
- Volunteers
- 182 people
- Sponsor
- National Taiwan University Hospital
Renal Tumor
Percutaneous Cryoablation Versus Partial Nephrectomy for T1b Renal Tumor
The aim of our study is to assess the long-term oncological and functional outcomes of cryoablation for T1b renal tumors, as well as such important parameters as the patient's quality of life after treatment, and to compare the…
- Trial name
- NCT04506671
- Testing
- Renal biopsy, Cryoablation, Partial nephrectomy
- Where
- Russia
- Volunteers
- 142 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Biliary Tract Cancer (BTC)
Cryoablation Combined With QL1706 (Iparomlimab/Tuvonralimab) Plus Lenvatinib in Patients With Advanced Biliary Tract Cancer.
This study will evaluate the efficacy and safety of cryoablation combined with QL1706 (iparomlimab/tuvonralimab) plus lenvatinib in patients with advanced biliary tract cancer (BTC) who have progressed after first-line treatment.
- Trial name
- CASTLE-ZS-04 (NCT07829874)
- Testing
- QL1706 (Iparomlimab/Tuvonralimab), Lenvatinib, Cryoablation
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Fudan University
Atrial Fibrillation
Continued Access Protocol
This Continued Access Protocol has been written to allow ongoing treatment of subjects at selected investigational sites while the marketing application for the Arctic Front® Cryoablation System is under review.
- Trial name
- CAP-AF (NCT00889681)
- Testing
- Arctic Front Cardiac Cryoablation System
- Where
- 10 sites in United States
- Volunteers
- 81 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Lung Cancer
Study of Core Needle Biopsy and Cryoablation of an Enlarging Tumor in Patients With Metastatic Lung Cancer and Metastatic Melanoma Receiving Post-progression Immune Checkpoint Inhibitor Therapy
This research study is studying cryoablation (a treatment to kill cancer cells with extreme cold) combined with continued treatment with current immune checkpoint inhibitor as a possible treatment for lung cancer.
- Trial name
- NCT03290677
- Testing
- Cryoablation, Biopsy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Atrial Fibrillation (Paroxysmal), Arrhythmias, Cardiac
CoolLoop Paroxysmal Atrial Fibrillation
This clinical investigation evaluates the safety of cryoablation (sclerotherapy of muscle tissue of the heart by freezing) in paroxysmal atrial fibrillation with the newly developed CoolLoop® cryoablation catheter.
- Conditions
- Atrial Fibrillation (Paroxysmal), Arrhythmias, Cardiac, Cardiovascular Diseases, Heart Diseases
- Trial name
- CoolLoop PAF (NCT02553239)
- Testing
- CoolLoop®
- Where
- 4 sites in Austria, Germany and 1 more
- Volunteers
- 20 people
- Sponsor
- afreeze GmbH
Prostate Cancer
Phase I Clinical Trial of Cryoimmunotherapy Against Prostate Cancer
20 patients with invasive castration resistant prostate cancer and radiologically verified metastases will be enrolled into the Phase I Clinical Trial. The trial is a dendritic cell based immunotherapy.
- Trial name
- CryoIT (NCT02423928)
- Testing
- Dendritic cell based cryoimmunotherapy, Cyclophosphamide, ipilimumab
- Where
- Norway
- Volunteers
- 18 people
- Sponsor
- Alden Cancer Therapy II