Clinical trials: Crying
Colic
Effect of a Prebiotic on Colic and Crying and Fussing Behaviour in Infants
Colic, or inconsolable crying and fussing, affects around 20% of babies who are 3 months of age or younger. To date, there are no known treatments that have been found to help reduce colic and its symptoms in babies.
- Trial name
- CRI (NCT02586558)
- Testing
- Experimental Infant formula, Reference group
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- McMaster University
Stool Assessment, Skin Rash
GI Symptoms in Infants Fed Goat Milk-based Infant Formula
A cross-sectional observational survey was conducted in Brazil, Mexico, Russia, and The Netherlands by recruiting parents/legal guardians through social media.
- Conditions
- Stool Assessment, Skin Rash, Urticaria, Regurgitation
- Trial name
- NCT06755424
- Where
- Netherlands
- Volunteers
- 425 people, healthy volunteers welcome
- Sponsor
- Ausnutria Hyproca B.V.
Anesthesia Outcomes, Anesthesia Complication
Does Style of Pre-sedation Instructions Improve Patient Outcomes in Ambulatory Anesthesia for Oral and Maxillofacial Surgery?
This randomized controlled trial aims to evaluate the impact of a brief guided visualization exercise on anesthesia-related outcomes in oral and maxillofacial surgery in patients scheduled for ambulatory anesthesia in the oral…
- Conditions
- Anesthesia Outcomes, Anesthesia Complication, Anesthesia and Procedure Related Time Intervals, Anesthesia Recovery Period
- Trial name
- NCT06768021
- Testing
- Guided visualization and standardized pre-sedation instructions, Standardized pre-sedation instructions only
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Alameda Health System
Infantile Colic
Effect of Probiotics on Infantile Colic Symptoms
The aim of this clinical trial is to assess the impact of B. lactis B94 on participants with infantile colic. It is hypothesized that participants given the probiotic formula will have a significant reduction in their crying…
- Trial name
- EPIC (NCT06385054)
- Testing
- Probiotic
- Where
- 10 sites in France
- Volunteers
- 70 people
- Sponsor
- Lallemand Health Solutions
Shaken Baby Syndrome, Crying
Effects of PURPLE Cry Intervention
The proposed study is designed to investigate whether the PURPLE Crying program attains efficacy by optimizing the neural response in the anterior insula, and augmenting activity in regions of the brain known to be important for…
- Conditions
- Shaken Baby Syndrome, Crying, Trauma
- Trial name
- NCT02227979
- Testing
- The Purple Cry Intervention, Control Intervention
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Emory University
Abuse, Child, Crying
Take 5 + Audio Clip Randomized Control Trial
At Yale New Haven Hospital, parents on the postpartum ward receive a Take 5 program to help train and prepare parents for strategies to manage their infant's crying.
- Conditions
- Abuse, Child, Crying, Parent-Child Relations
- Trial name
- NCT04608877
- Testing
- Take 5 and Audio Clip, Take 5 Only
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Yale University
Pain
The Effect of Gentle Human Touch and Kangaroo Care on Pain and Crying Physiological Parameters During Hepatitis-B Vaccination in a Newborn
Many short- and long-term consequences, including altered physiological parameters, issues with feeding and sleep, chronic pain syndrome, difficulty focusing, anxiety, cognitive behavioral disorders, adjustment disorders, and…
- Trial name
- NCT06196502
- Testing
- Gentle Human Touch (GHT), Kangaroo Care, Lactation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Preterm, Chronobiology
The Effect of Oral Feeding Model With a Chronobiological Approach in Neonates
The ideal food for healthy term babies as well as preterm babies and sick term babies is breast milk. There are many studies showing that the composition of breast milk can vary from mother to mother, according to the baby's…
- Conditions
- Preterm, Chronobiology, Human Milk/Breastfeeding, Bottle Feeding
- Trial name
- NCT06821672
- Testing
- Chronobiological Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Bilgi University
Upper Respiratory Tract Infection, Nasal Congestion and Inflammations
Examination of the Effectiveness of Nasal Irrigation Techniques in Infants With Nasal Congestion
The research investigates the effects of high-volume and low-volume nasal irrigation techniques applied to relieve nasal congestion in infants with nasal congestion due to upper respiratory tract infections.
- Trial name
- NCT06002594
- Testing
- group low-volume irrigation, group high-volume irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Newborn; Vitality, Premature Infants
Infant Crying, a Bioacoustic Prognostic Signal for Neurodevelopment
Crying is a vital communication signal for the baby. Product of a complex physiological process, it reflects not only the organization and functioning of the cortical central nervous system and the function of sympathetic and…
- Conditions
- Newborn; Vitality, Premature Infants, Infant Development
- Trial name
- BABYCRY_1000 (NCT06332521)
- Testing
- Acoustic signal analysis method
- Where
- France
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Nursing Caries
Heel Warming With Mild and Hot Thermofor Applied Before Heel Lance
Heel warming with thermophor during heel blood collection is a cost-effective and easy-to-apply method. In previous studies, it has been shown that applying heat to the heel reduces the pain of taking heel blood, increases…
- Trial name
- NCT05228366
- Testing
- Heel warming with mild thermofor group, Heel warming with hot thermofor group, Ineffective heel warming with thermofor group
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Isparta University of Applied Sciences
Infant Colics
Impact of Probiotic Preparation VSL#3 on Infants Colics
Infantile colic is one of the most commonly reported medical problems within the first three months of life causing appreciable distress for both parents and pediatricians.
- Trial name
- NCT01869426
- Testing
- VSL#3 drops
- Where
- Italy
- Volunteers
- 62 people
- Sponsor
- Policlinico Hospital
Infantile Colic, Infant Sleeping Habits
Role of ProTectis on Infant Colic and Its Effect on Infant Crying Time and Maternal Mental Health
This study will work on hypothetical assumption that compared to the arm supplemented with placebo (control) group; the L reuteri (intervention) group will lower daily crying/fussing time per 24 hours at one month post…
- Conditions
- Infantile Colic, Infant Sleeping Habits, Maternal Mental Health.
- Trial name
- PRIC-SMM (NCT02094092)
- Testing
- ProTectis drops (five drops per day) for 21 days
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Ferozsons Laboratories Ltd.
Multiple Sclerosis
Safety and Efficacy of AVP-923 for Pseudobulbar Affect in Multiple Sclerosis Patients
Pseudobulbar Affect is a condition characterized by frequent episodes of laughing and crying out of proportion. Other terms used to describe this condition include emotional lability, emotionalism, emotion incontinence, emotional…
- Trial name
- NCT00050232
- Testing
- AVP-923
- Where
- 20 sites in United States
- Volunteers
- 96 people
- Sponsor
- Avanir Pharmaceuticals
Nasal Congestion, Nursing
Effects of Different Nasal Irrigation Methods on Pain Level, Crying and Procedure Times in Nasal Congestion in Infants
This study aimed to evaluate the effects of different nasal irrigation (NI) methods for relieving nasal obstruction on pain, crying and procedure times, and physiologic parameters in infants with acute upper respiratory tract…
- Trial name
- NCT06691620
- Testing
- Nasal irrigation with isotonic saline, Nasal irrigation with hypertonic saline, Nontraumatic nasopharyngeal aspiration
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Infantile Colic
Effects of Vivatlac Baby on Crying Behavior of Colicky Babies
Open trial with two parallel arms, assessing the effects of Simethicone and Vivatlac Baby in babies diagnosed for infantile colic.
- Trial name
- NCT04487834
- Testing
- Simethicone Solution, Vivatlac Baby
- Where
- 2 sites in Poland
- Volunteers
- 87 people
- Sponsor
- The President Stanisław Wojciechowski State University of Applied Sciences in Kalisz
Pain, Acute, Newborn
Effect of Mother's Touch and Nurse's Therapeutic Touch on Pain Level and Crying Time During Heel Blood Collection
This prospective study is planned as a randomized controlled study with the purpose of determining the effect of Mother's Touch and Nurse's Therapeutic Touch on pain levels and crying times by newborns during heel blood…
- Conditions
- Pain, Acute, Newborn, Crying
- Trial name
- NCT06350084
- Testing
- Mother's Touch, Nurse's Therapeutic Touch
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Burdur Mehmet Akif Ersoy University
Pain, Fear
The Effect of the Helfer Skin Tap and Buzzy Application on Vaccination Pain, Fear and Crying Duration
To minimize the pain and discomfort during vaccination, one of three different methods will be used. One method involves using 'Buzzy,' a small, bee-shaped device that provides vibration and a cooling sensation; another involves…
- Conditions
- Pain, Fear, Crying
- Trial name
- NCT07749235
- Testing
- Bee Buzzy, Helfer Skin TAp
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ege University
Crying Time in Colicky Infants
Effects on Crying Time in Colicky Infants With the Supplementation of Lactobacillus Reuteri DSM 17938
Infant colic is a common condition characterized by excessive crying. The otherwise healthy infant aged less than 3 months is difficult to console during the periods with crying.
- Trial name
- NCT02574065
- Testing
- L. reuteri DSM 17938
- Where
- China
- Volunteers
- 116 people
- Sponsor
- Shanghai Children's Hospital
Pain Management, Newborn Pain
Nonpharmacological Methods in Heel Stick Pain
In the present study, the randomized controlled and experimental design is used because it was aimed to determine the effects of two different warming methods (warming with a thermophore heating pad and warming with a warm towel)…
- Trial name
- NCT06847048
- Testing
- Thermophore pad warming group, Warm towel warming group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Diler Yilmaz