Clinical trials: Croup
Stridor
Comparison Between Budesonide and Dexamethasone Treatments for Respiratory Discomfort After Extubation on Children
The study aims to analyze and compare the clinical effects of using inhaled budesonide or intravenous dexamethasone in the treatment of postextubation stridor on children admitted to the pediatric intensive care units at Hospital…
- Trial name
- BUDEXA (NCT02056379)
- Testing
- Budesonide, Dexamethasone
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Hospital Israelita Albert Einstein
Gastroesophageal Reflux Disease, Chronic Laryngitis
Laryngeal and Esophageal EGF-r Expression in Patients With Reflux Laryngitis
Saliva plays an important role in the homeostasis of the digestive tract mucosa. Salivary organic components, such as the Epidermal Growth Factor(EGF) have been found in defficient concentrations in patients with gastroesophageal…
- Trial name
- EGFR (NCT01806220)
- Testing
- Biopsy of the retrocrycoid laryngeal mucosa, Biopsy of the distal esophageal mucosa
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Sore-throat, Upper Respiratory Infection
Clinical Trial of a Mouth and Throat Rinse for the Treatment of Acute Sore Throat
The aim of this study is to confirm the efficacy, safety and tolerability of the Mouth and Throat Rinse in adult participants with acute sore throat (upper respiratory tract infection e.g., pharyngitis/laryngitis) compared to…
- Trial name
- NCT06244615
- Testing
- Verum (WO 6607)
- Where
- Ukraine
- Volunteers
- 154 people
- Sponsor
- Dr. August Wolff GmbH & Co. KG Arzneimittel
Asthma, Candidiasis, Oral
Study to Assess the Incidence of Local Oropharyngeal and Laryngeal Adverse Effects of Advair DISKUS 250/50 mcg BID
This Pilot study is designed to explore the rate of local side effects of fluticasone as delivered by Advair and to determine the best outcome measure to assess these effects.
- Conditions
- Asthma, Candidiasis, Oral, Voice Disorders
- Trial name
- NCT00235053
- Testing
- fluticasone/salmeterol DISKUS 250/50
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Allergy & Asthma Medical Group & Research Center
Respiratory Distress Syndrome, Pneumonia
Telemedicine in the Generals Practitioners Office
Pediatrician does physical examination through telemedicine and in real life to see whether the telemedicine consultation corresponds with the real life examination. Goal is to determine: 1. Check practical feasability 2.
- Conditions
- Respiratory Distress Syndrome, Pneumonia, Bronchiolitis, Croup
- Trial name
- NCT04168554
- Testing
- Telemedicine
- Volunteers
- 40 people
- Sponsor
- Rijnstate Hospital
Croup, Epinephrine, Administration, Inhalation
The Effect and Safety of Low Dose Nebulized Epinephrine in Croup
Croup is common illness presenting emergency department with dyspnea. The main treatment for croup is nebulized L-epinephrine and steroid.
- Trial name
- NCT01664507
- Testing
- conventional dose epinephrine, low dose epinephrine
- Where
- South Korea
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Laryngopharyngeal Reflux
Safety and Efficacy of Lansoprazole 30mg Twice Daily in Treatment of Laryngitis Associated With Gastroesophageal Reflux
The purpose of this study is to determine whether Lansoprazole 30mg taken twice daily is effective in the treatment of laryngitis due to gastroesophageal reflux.
- Trial name
- NCT00369265
- Testing
- Lansoprazole, Sugar pill
- Where
- 3 sites in United States
- Volunteers
- 18 people
- Sponsor
- American Institute for Voice and Ear Research
Pharyngitis
Efficacy and Safety of Meloxicam Suspension Versus Diclofenac Suspension or Nimesulide Suspension in Patients With a Diagnosis of Acute, Non-bacterial Pharyngitis, Pharyngotonsillitis or Laryngitis
The objective of this study was to assess the clinical efficacy and safety of meloxicam suspension 0.25 mg/kg/day once a day, versus diclofenac suspension 1 mg/kg/day twice a day or nimesulide suspension 4 mg/kg/day twice a day…
- Trial name
- NCT02229747
- Testing
- Meloxicam, Diclofenac, Nimesulide
- Volunteers
- 128 people
- Sponsor
- Boehringer Ingelheim
Acute Otitis Media, Allergic Rhinitis
A Trial of Point of Care Information in Ambulatory Pediatrics
Does presentation of clinical evidence for decision making at point-of-care improve prescribing patterns in ambulatory pediatrics?
- Conditions
- Acute Otitis Media, Allergic Rhinitis, Sinusitis, Constipation
- Trial name
- NCT00368823
- Testing
- Electronic point-of-care delivery system
- Where
- 2 sites in United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Washington
Laryngopharyngeal Reflux
Laryngopharyngeal Reflux and Proton Pump Inhibitor (PPI) Treatment
This study proposes to investigate prospectively, the presence of molecular markers for inflammation in laryngopharyngeal reflux (LPR) patients and to study the effect of a proton pump inhibitor (Aciphex) on these molecular…
- Trial name
- NCT00204698
- Testing
- Aciphex
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Utah
Laryngopharyngeal Reflux (LPR)
Quality of Life Validation in Laryngitis
The primary purpose of this study was to establish the psychometric properties of a new disease specific Quality of Life questionnaire, the LPR-HRQL.
- Trial name
- NCT00641264
- Testing
- Omeprazole, Quality of Life questionnaire
- Volunteers
- 90 people
- Sponsor
- AstraZeneca
Asthma
Study Of Airway Physiology In Adults. SERETIDE DISKUS® Inhaler and FLIXOTIDE® Inhaler Are Trademarks of GSK Croup of Companies.
Comparison of two asthma treatments by lung function measures.
- Trial name
- NCT00370591
- Testing
- Salmeterol/fluticasone propionate and fluticasone propionate
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- GlaxoSmithKline
Recurrent Upper-Respiratory Tract Infections
CLEARI (Clinical Efficacy Assessment on Recurrent Upper-Respiratory Tract Infections) Study
The purpose of this study is to assess the efficacy and safety of J022X ST for prevention of Recurrent Upper-Respiratory Tract Infections (RURTI) compared to placebo in children of younger age who develop infectious diseases more…
- Trial name
- NCT01948856
- Testing
- J022X ST
- Where
- 24 sites in Italy, Lithuania and 3 more
- Volunteers
- 1,003 people
- Sponsor
- Pierre Fabre Medicament
Pneumonia, Bronchiolitis
Diagnosing Respiratory Disease in Children Using Cough Sounds 2
The purpose of this prospective study is to evaluate the efficacy of the ResAppDx software application in the diagnosis of childhood acute respiratory disease, including pneumonia, bronchiolitis, asthma/reactive airways disease…
- Conditions
- Pneumonia, Bronchiolitis, Asthma Exacerbation, Croup
- Trial name
- SMARTCOUGH-C-2 (NCT03392363)
- Testing
- Recordings of Infants and Children's Cough Sounds
- Where
- 3 sites in United States
- Volunteers
- 1,470 people
- Sponsor
- ResApp Health Limited
Laryngotracheobronchitis, Croup
Efficacy Of Oral Dexamethasone Versus Parenteral Dexamethasone In The Management Of Mild To Moderate Croup
Croup (laryngotracheobronchitis) is a viral infection of the upper airway that causes throat swelling, leading to a barking cough, stridor, and hoarseness.
- Trial name
- NCT06959407
- Testing
- oral dexamethasone, intramuscular dexamethasone
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Arooj Khan
Acute Pharyngitis, Acute Laryngitis
Non Interventional Study (NIS) Regarding the Application of Ectoin Mund- & Rachenspray in Patients With Acute Laryngitis and/or Acute Pharyngitis
In this observational study insights regarding the tolerability and influence on the quality of life of the topical treatment Ectoin Mund- and Rachenspray compared to Emser Pastillen in patients with acute Pharyngitis/ Laryngitis…
- Trial name
- NCT02160912
- Where
- 8 sites in Germany
- Volunteers
- 95 people
- Sponsor
- Bitop AG
Gastroesophageal Reflux, Laryngitis
Prospective Double-blinded Randomized Controlled Trial of 12-weeks High Dose Rabeprazole (Pariet) in the Treatment of Reflux Laryngitis in Chinese Patients
The purpose of this study is to evaluate the efficacy of rabeprazole (pariet) versus placebo in treating reflux laryngitis in Chinese patients.
- Trial name
- NCT00517114
- Testing
- Rabeprazole 20mg twice daily
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Hospital Authority, Hong Kong
Sinusitis, Otitis
Complicated Infections in Otorhinolaryngology
This observational study aims to learn more about complicated infections treated by otorhinolaryngologists. The main questions to answer are: What is the management of complicated sinonasal infections in Ljubljana, Slovenia, What…
- Conditions
- Sinusitis, Otitis, Laryngitis, Lymphadenitis
- Trial name
- ENT_infect (NCT06023550)
- Testing
- Treatment with surgery and/or conservative measures
- Where
- Slovenia
- Volunteers
- 2,550 people
- Sponsor
- University Medical Centre Ljubljana
Asthma, Respiratory Tract Infections
VItamin D in pregnanCy for prevenTion Of eaRlY Childhood Asthma
The overall aim of the study is to develop a nutritional preventive vitamin D supplementation strategy in pregnancy for early childhood asthma/persistent wheeze during the first three years of life as we hypothesize that…
- Conditions
- Asthma, Respiratory Tract Infections, Gastrointestinal Infection, Croup
- Trial name
- VICTORY (NCT06570889)
- Testing
- Cholecalciferol D3, Olive oil
- Where
- Denmark
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Professor Klaus Bønnelykke
Croup
Community Care for Croup (RCT)
This randomized clinical trial was to compare the effectiveness of prednisone 2mg/kg/day for 3 days vs. dexamethasone 0.6mg/kg for 1 day for treatment of children with mild or moderate croup.
- Trial name
- NCT01042145
- Testing
- Prednisone, Dexamethasone
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Washington University School of Medicine