Clinical trials: Cross Infection
Post-Viral Fatigue Syndrome, Post-Viral Disorder (Disorder)
Study to Evaluate the Benefit of RUCONEST in Improving Neurological Symptoms in Post COVID-19 Infection
Randomized, Double Blind, Placebo Controlled, Proof-of-Concept Study to Evaluate the Benefit of RUCONEST in Improving Neurological Symptoms in Post-SARS-CoV-2 Infection.
- Conditions
- Post-Viral Fatigue Syndrome, Post-Viral Disorder (Disorder), Covid19
- Trial name
- NCT04705831
- Testing
- Ruconest
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- IMMUNOe Research Centers
Early Ventilator Associated Pneumonia
Duration of Antibiotic Treatment for Early VAP (DATE) Trial
Hypothesis: 4 days of antibiotic therapy, as compared to 8 days, is equally effective and results in decreased antibiotic exposure among surgical ICU patients with early VAP.
- Trial name
- DATE (NCT01994980)
- Testing
- Default 4 days antibiotic therapy
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Denver Health and Hospital Authority
Surgical Site Infections
St. Barbara Specialised Regional Hospital No. 5: Surveillance of Healthcare-Associated Infections
Retrospective laboratory-based data collection study of surgical site infections: Surveillance of Healthcare-Associated Infections in Orthopaedic and Trauma Surgery Unit in Sosnowiec, Poland;
- Trial name
- NCT03686553
- Testing
- laboratory-based data collection
- Volunteers
- 5,239 people
- Sponsor
- Polskie Towarzystwo Zakażeń Szpitalnych
Aging, Frailty
Effect of Infections and Global DNA Methylation on Frailty Trajectories in Hospitalized Older Patients (INFRAGEN)
This prospective multicenter study aims at exploring the impact of infections on intra-hospital and 3-month changes in the frailty profile of older inpatients.
- Conditions
- Aging, Frailty, Telomere Shortening, Inflammation
- Trial name
- INFRAGEN (NCT06430073)
- Volunteers
- 340 people
- Sponsor
- University Hospital of Ferrara
Antibiotic, Healthcare Associated Infection
Evaluating Antibiotic Stewardship Assisted by Computer in the University Hospital of Nancy (MACABAO)
Antibiotic resistance is one of the most pressing health threats that mankind faces now and in the coming decades. Antibiotic resistance leads to longer hospital stays, higher medical costs and increased mortality.
- Trial name
- MACABAO (NCT04976829)
- Testing
- Antibiotic stewardship and healthcare-associated infections surveillance assisted by computer
- Volunteers
- 100,000 people
- Sponsor
- Central Hospital, Nancy, France
Pneumonia, Ventilator-Associated
Bilateral Bronchoalveolar Lavage in Ventilator-associated Pneumonia
The purpose of this study is to assess microbiologic concordance rates between right- and left-lung bronchoalveolar lavage cultures from patients with suspected ventilator-associated pneumonia, identify predictors of concordance…
- Trial name
- NCT02542553
- Testing
- Bilateral BAL
- Volunteers
- 79 people
- Sponsor
- Catholic University of the Sacred Heart
Age-related Cognitive Decline
The Dortmund Vital Study: Impact of Biological and Lifestyle Factors on Cognitive Performace and Work Ability
The goal of the Dortmund Vital Study is to validate previous hypotheses and to generate and validate new hypotheses about the relationship of ageing, working conditions, genetic makeup, stress, metabolic functions, cardiovascular…
- Trial name
- DVS (NCT05155397)
- Where
- Germany
- Volunteers
- 627 people, healthy volunteers welcome
- Sponsor
- Technical University of Dortmund
Nosocomial Infections, Sepsis
Safety and Efficacy of Veronate® Versus Placebo in Preventing Nosocomial Staphylococcal Sepsis in Premature Infants
The purpose of this study is to show whether Veronate, a donor-selected staphylococcal human immune globulin intravenous (IGIV), can prevent an infection in the blood caused by staphylococcal bacteria in premature babies weighing…
- Conditions
- Nosocomial Infections, Sepsis, Staphylococcal Infections, Candidemia
- Trial name
- NCT00113191
- Testing
- Veronate
- Where
- 93 sites in United States, Canada
- Volunteers
- 2,000 people
- Sponsor
- Bristol-Myers Squibb
Periodontal Diseases, Gingival Diseases
Asprosin and Total Antioxidant/Oxidant Status in Diabetes and Periodontal Disease
The goal of this observational study is to learn about how different periodontal health status affects the levels of asprosin (a hormone) and total oxidant/antioxidant status in the gingival crevicular fluid and blood serum of…
- Conditions
- Periodontal Diseases, Gingival Diseases, Type 2 Diabetes
- Trial name
- NCT07691060
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Pneumonia
M-ROSE Combined With mNGS in Severe Hospital-acquired Pneumonia
The purpose of this study is to determine the value of M-ROSE（microbiological rapid on-site evaluation）in severe hospital-acquired pneumonia.
- Trial name
- NCT05300776
- Testing
- M-ROSE analysis
- Where
- China
- Volunteers
- 166 people
- Sponsor
- Chinese PLA General Hospital
Hemifacial Paralysis, Bell Palsy
Electrical Stimulation to Improve Recovery After Peripheral Nerve Injury
After nerve injury and facial palsy, many patients have permanent muscle and sensory dysfunction. Electrical stimulation (ES) of injured nerves may speed up axon growth and improve recovery.
- Trial name
- NCT03996525
- Testing
- Electrical Stimulation
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- The Hospital for Sick Children
Ventilator Associated Pneumonia (VAP), Evidence Based Practice
Effect of Implementing Evidence-based Practice and Nurse's Behavior Change on Quality of Care in Intensive Care Unit: Focus on Ventilator Associated Pneumonia in a Tertiary Hospital in Bangladesh
Quality of care is crucial for preventing adverse events such as infection in the intensive care units (ICUs). The most common ICU-acquired infections include pneumonia such as ventilator-associated pneumonia (VAP), Central Line…
- Trial name
- EBP in Nursing (NCT06624540)
- Testing
- This is a pre- and post- quasi-experimental study., Education with EBP
- Where
- 2 sites in Bangladesh, Japan
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- Hiroshima University
Chronic Hepatitis B
Residual Histological Disease Across Treatment Pathways in Chronic Hepatitis B
This retrospective, two-center observational study evaluates contemporary non-biopsy treatment pathways in treatment-naïve adults with chronic hepatitis B who underwent liver biopsy in routine clinical practice.
- Trial name
- CHB-PATH (NCT07843446)
- Where
- Turkey (Türkiye)
- Volunteers
- 1,201 people
- Sponsor
- Istanbul Medeniyet University
HIV/AIDS, Gender
Transgender Youth and PrEP: PK, Safety, Uptake & Adherence - PK Study
To address the critical scientific gaps in PrEP safety for transgender youth and to plan for appropriate implementation of PrEP in transgender youth communities, the study will be conducted in 3 integrated phases.
- Conditions
- HIV/AIDS, Gender, Behavior and Behavior Mechanisms
- Trial name
- NCT03652623
- Testing
- TDF/FTC
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Hektoen Institute for Medical Research
Coronavirus Disease, SARS-CoV-2 Infection
ImmuneSense™ COVID-19 Cross-Reactivity Study
Adaptive Biotechnologies has developed a clinical test called T-Detect COVID Test that can identify a T-cell response to the SARS-CoV-2 virus, indicating recent or prior infection This study aims to evaluate the potential…
- Trial name
- NCT05112874
- Where
- United States
- Sponsor
- Adaptive Biotechnologies
Nosocomial Infections
Multi-center Observational Study to Evaluate Epidemiology and Resistance Patterns of Common ICU-Infections (MOSER)
Most literature on ICU infections and the resistant patterns comes from the western literature. This data may not truly reflect the incidence, epidemiology and resistance patterns in developing countries such as India.
- Trial name
- MOSER (NCT01346735)
- Testing
- No intervention
- Where
- India
- Volunteers
- 381 people
- Sponsor
- Indian Society of Critical Care Medicine
Infections, Nosocomial, Infections, Respiratory Tract
Antibacterial Effect of Zinc Oxide Nanoparticles on Acinetobacter Baumannii Isolated From Patients With Hospital Acquired Infections in Sohag University Hospitals, Egypt
A. baumannii is known as the most frequently isolated organism in intensive care units (ICUs), causing a variety of nosocomial infections, including pneumonia, urinary tract infections (UTIs), bacteremia as well as skin and soft…
- Trial name
- NCT06628076
- Testing
- Culture specific antibiotic therapy, Antibiotic, Biofilm assessment
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Sohag University
Healthcare Associated Infection, Clostridium Difficile Infection
Pulsed UV Xenon Disinfection to Prevent Resistant Healthcare Associated Infection
The objective is to conduct a prospective, sham controlled, double-blinded, interventional crossover trial to compare standard terminal cleaning plus PX-UV (intervention) with standard terminal cleaning plus sham PX-UV (control)…
- Conditions
- Healthcare Associated Infection, Clostridium Difficile Infection, Infection Due to Multidrug Resistant Bacteria
- Trial name
- NCT03349268
- Testing
- Pulsed xenon ultraviolet (PX-UV) Device
- Where
- United States
- Volunteers
- 25,732 people
- Sponsor
- University of Michigan
HIV, AIDS
HIV Indicator Diseases Survey Across Europe - UK Arm
In Europe many patients infected with HIV remain undiagnosed, although this percentage varies between 15-80% across the continent. In the UK it is estimated to be 27%.
- Conditions
- HIV, AIDS, Indicator Diseases/Indicator Conditions
- Trial name
- NCT01196468
- Testing
- HIV test (serological or salivary), Interview
- Where
- 2 sites in United Kingdom
- Volunteers
- 2,000 people
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Intubated Patient Requiring a Gastric Tube
Impact of the Choice of Gastric Tube Placement Sites on the Incidence of Ventilator Associated Pneumonia
In intensive care, many gastric tubes are inserted on a regular basis. There are different practices in terms of the location of the gastric tube.
- Trial name
- SONG (NCT05915663)
- Testing
- nasogastric tube and orogastric tube, orogastric tube and nasogastric tube
- Where
- 16 sites in France
- Volunteers
- 2,400 people
- Sponsor
- Centre Hospitalier le Mans