Clinical trials: Craving
Opioid Use Disorder, Tobacco Use Disorder
Deep Transcranial Magnetic Stimulation for Tobacco Cessation in Adults With Opioid Use Disorder
This pilot study will evaluate the use of deep transcranial magnetic stimulation (Deep TMS) to help adults with opioid use disorder (OUD) who are receiving medications for opioid use disorder (MOUD) such as buprenorphine or…
- Trial name
- NCT07770555
- Testing
- Deep TMS System With H4 Coil
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Payel Roy
Alcohol Dependence
CRF1 Antagonist GSK561679 in Alcoholism
Objective: To evaluate GSK561679, an orally available, brain penetrant selective CRH1 antagonist for its ability to reduce alcohol craving in recently detoxified alcohol dependent women in response to stress or alcohol-associated…
- Trial name
- NCT01187511
- Testing
- GSK561679
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Eating Behavior, Overweight
Snacks and Satiety
This study is designed to compare two types of snacks (almonds or a cereal-based snack), eaten between meals, on measures of appetite, including appetitive hormones, self-reported feelings of hunger and fullness, and food intake…
- Conditions
- Eating Behavior, Overweight, Obesity
- Trial name
- NCT03947281
- Testing
- Almond snack, Cereal-based snack
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Substance-Related Disorders
Transcranial Direct Current Stimulation on Inhibitory Control in Addictions.
The research in neuroscience of the last 20 years is defined, in addition to continuing to advance in the field of behavioral and pharmacological therapy, by the birth and development of a new therapeutic category, called…
- Trial name
- NCT05350033
- Testing
- tDCS - tDCS
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Universidad de Almeria
Healthy, Nutrition, Healthy
Postprandial Metabolic and Appetite Responses to Different Food Intake Sequences in Athletes
Emerging evidence suggests that following a 'carbohydrate-last meal pattern', wherein foods rich in protein, fat, fiber, and/or polyphenols are consumed before sources of simple carbohydrate (CHO) in a meal, results in reduced…
- Conditions
- Healthy, Nutrition, Healthy, Postprandial Hyperglycemia, Hunger
- Trial name
- NCT06365385
- Testing
- Carbohydrate-last meal pattern, Carbohydrate-first meal pattern
- Where
- Portugal
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Cocaine Dependence, Cocaine Use Disorder
Predicting Relapse After Cocaine Inpatient Cessation
Can brain MRI at entry of cocaine inpatient cessation attempt predict relapse during a three month follow-up ? Hypothesis : White matter losses in the prefrontal cortex are associated with relapse to cocaine use.
- Trial name
- QUIT-COC (NCT02416050)
- Testing
- Brain MRI imagery
- Where
- France
- Volunteers
- 87 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cocaine Abuse, Heroin Abuse
Effect of Clonidine on Responses to Imagery Scripts
Background: Research has shown that clonidine, a drug originally prescribed to treat high blood pressure and some symptoms of opioid withdrawal, can help block stress-induced relapse to heroin and cocaine seeking in rats.
- Trial name
- NCT00318760
- Testing
- Clonidine
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Depression, Anxiety
Ecological Momentary Assessment of State-Dependent Decision-Making and Metacognition Across a Psychopathology Continuum
Background: Making decisions during daily life is a complicated behavior. Even simple choices can be affected by a range of emotions, stresses, and moods.
- Conditions
- Depression, Anxiety, Addiction, Emotion
- Trial name
- NCT07801079
- Where
- 2 sites in United States
- Volunteers
- 420 people
- Sponsor
- National Institute of Mental Health (NIMH)
Alcohol Dependence, Cocaine Dependence
Human Behavioral Pharmacology Laboratory (HBPL) Study of Varenicline's Impact on Cocaine and Alcohol Craving
This is a Phase II within-subjects double-blind placebo-controlled human laboratory study. The purpose of the study is to determine the efficacy of varenicline (Chantix) for reducing cue-induced cocaine and alcohol craving.
- Trial name
- NCT01151813
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Pennsylvania