Clinical trials: Couples
Behavior and Behavior Mechanisms
Couple & Family Contexts
The purpose of this study is to understand the factors that lead to adolescent sexual risk behavior by investigating both the family contexts and romantic relationships that influence adolescent couples' decision-making.
- Trial name
- CFC (NCT01631721)
- Where
- United States
- Volunteers
- 2,960 people, healthy volunteers welcome
- Sponsor
- New York University
Relational Problems, Couples
The Effects of Relational Letter Writing
The main objective of this research is to explore the relational letter writing technique as an intervention for improving couples' relational well-being. This is a two-arm superiority randomized clinical trial.
- Trial name
- NCT05194683
- Testing
- Relational Letter Writing
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Universitat Oberta de Catalunya
Couples
Project Nexus: Providing Online Counseling for Home-Based HIV Testing
The proposed research aims to address the question: Compared to the current standard of care for home-based HIV tests, in which persons conduct and interpret HIV tests without counseling, does the addition of video conferencing…
- Trial name
- NCT02335138
- Testing
- Couples HIV Testing and Counseling (CHTC, CVCT), at-home test kit
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University of Michigan
HIV, Pregnancy
Promoting Male Involvement to Improve Prevention of Mother to Child Transmission (PMTCT) Uptake and Reduce Antenatal Infection
This study will evaluate the impact of combining two evidence-based interventions: a couples risk reduction intervention with an evidence based medication adherence intervention designed to enhance male participation in…
- Trial name
- NCT01448512
- Testing
- PartnerPlus Intervention, Usual Care
- Where
- South Africa
- Volunteers
- 478 people, healthy volunteers welcome
- Sponsor
- University of Miami
Perinatal Depression, Perinatal Anxiety
Cognitive Behavioral Couple Therapy for Perinatal Distress
The hypotheses of the study are There will be differences in perceived perinatal distress, dyadic coping strategies, social support, domains of quality of life, and well-being in couples at Pre- and Post-Test levels during the…
- Trial name
- NCT06001021
- Testing
- Psychopharmacological Intervention, Cognitive Behavioral Couple Therapy, Combination of Psychopharmacological Intervention and CBCT
- Where
- Pakistan
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Sameera Shafiq
Human Immunodeficiency Virus
Simunye: A Couples-focused Intervention for HIV Prevention and Care in South Africa
From a sample of 272 male-female couples (544 individuals, 272 men and 272 women) recruited from rural KaZulu-Natal, South Africa, couples will be randomized to receive either individual a package of dyadic counseling and testing…
- Trial name
- NCT05231707
- Testing
- A couples-focused intervention for HIV prevention and care in South Africa
- Where
- South Africa
- Volunteers
- 544 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Committed Couple Expecting a Child, Parenting
Impact Evaluation of Family Expectations: A Program to Strengthen the Relationships of Disadvantaged Expectant Couples
This study investigates the effectiveness of a program to strengthen the relationships of disadvantaged expectant couples, and to increase co-parenting, father involvement, and economic stability.
- Conditions
- Committed Couple Expecting a Child, Parenting, Family Relations
- Trial name
- NCT03058549
- Testing
- Family Expectations
- Where
- United States
- Volunteers
- 2,640 people, healthy volunteers welcome
- Sponsor
- Public Strategies
HIV Infections, Substance Use Disorders
Couples ART Adherence Intervention for PWID in Kazakhstan
The fastest growing HIV epidemics globally are driven by injection drug use, but only a small percentage of HIV-positive people who inject drugs (PWID) have achieved viral suppression.
- Trial name
- NCT03555396
- Testing
- SMART Couples 2, Standard of Care
- Where
- Kazakhstan
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Columbia University
Infertility, Assisted Reproductive Technology
Microbiome and Metabolome Profiles in Couples Undergoing IVF and Reproductive Outcomes
This prospective observational cohort study investigates the role of the microbiome and metabolome in couples undergoing in vitro fertilization.
- Conditions
- Infertility, Assisted Reproductive Technology, Pregnancy Complications, Pregnancy Loss, Early
- Trial name
- Mi IVF (NCT07532629)
- Where
- 3 sites in Sweden
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Human Immunodeficiency Virus
Testing Strategies for Couple Engagement in PMTCT and Family Health in Kenya
This study will test the efficacy and cost-effectiveness of an interdependence theory-based couples intervention in Kenya that reaches pregnant women and male partners through home visits by male-female pairs of lay health…
- Trial name
- Jamii Bora (NCT03547739)
- Testing
- Home visits, HIV Self-testing
- Where
- Kenya
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Alcohol; Use, Problem
Using EMA Data to Inform a Web-intervention for Couples Concerned About Drinking
Alcohol misuse is a prevalent and serious problem with significant harms to society, individuals, and their relationships. Romantic partners have a strong influence on their partner's behavior, uniquely positioning them as a…
- Trial name
- NCT06501677
- Testing
- WBI
- Where
- United States
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Stanford University
HIV/AIDS
Demand Creation for Couples' HIV Counseling and Testing
This study aims at assessing the effect of a demand-creation intervention on couples' HIV counseling and testing (couples' HCT) uptake among married couples who have never tested together as a couple.
- Trial name
- NCT02492061
- Testing
- Demand creation for couples' HCT
- Volunteers
- 3,076 people, healthy volunteers welcome
- Sponsor
- Makerere University
Prostate Cancer
Sexual and Urological Rehabilitation to Men Operated for Prostate Cancer and Their Partners
Today prostate cancer (PC) treatment with curative intent is primarily surgical removal of the prostate gland (prostatectomy) which may be associated with immediate and long lasting erectile dysfunction and decline in urinary…
- Trial name
- PROCAN (NCT02103088)
- Testing
- Sexual and urological intervention
- Where
- Denmark
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Danish Cancer Society
Depression, Couples (Persons)
Social Interaction and Compassion in Depression
The purpose of this study is to determine how a CBCT® (Cognitively Based Compassion-Training) for couples affect aspects of health and especially social interactions in depressed female patients and their romantic partners.
- Trial name
- SIDE (NCT03080025)
- Testing
- CBCT® (Cognitively Based Compassion-Training)
- Where
- Germany
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
HIV
Home-based Partner Education and Testing (HOPE) Study
The purpose of this study is to investigate the impacts of home-based couple HIV-testing and counseling and male partner education on partner HIV testing and other critical maternal and infant health outcomes during pregnancy and…
- Trial name
- HOPE (NCT01784783)
- Testing
- HOPE Intervention, INVITE Intervention
- Where
- Kenya
- Volunteers
- 601 people, healthy volunteers welcome
- Sponsor
- University of Washington
Neoplasms, Fatigue
COMPANION: A Couple Intervention Targeting Cancer-related Fatigue
Chronic cancer-related fatigue (CCRF) is a disturbing condition that persists in up to 25% of cancer patients after completion of treatment.
- Trial name
- COMPANION (NCT05636696)
- Testing
- Samen Minder Moe (Dutch intervention name)
- Where
- 2 sites in Netherlands
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Mariët Hagedoorn
Human Papillomavirus Infection
Transmission Reduction and Prevention With HPV Vaccination (TRAP-HPV) Study
Human papillomavirus (HPV) is a member of the Papillomaviridae family of DNA viruses that is capable of infecting humans. HPV infection can cause cancers of the cervix, vulva, vagina, and anus in women or cancers of the anus and…
- Trial name
- TRAP-HPV (NCT01824537)
- Testing
- HPV vaccine, Gardasil 9, Hepatitis A vaccine
- Where
- Canada
- Volunteers
- 372 people, healthy volunteers welcome
- Sponsor
- McGill University
Pregnancy, Postpartum Period
The Effect of Sexual Education-Counseling According to PLISSIT Model of Couples' Sexual Functions During Pregnancy and Postpartum
Sexuality is a natural part of human life at every stage of life. It is a multidimensional phenomenon influenced by biological, psychological, social, interpersonal and cultural factors.
- Conditions
- Pregnancy, Postpartum Period, Sexual Dysfunction, PLISSIT Model
- Trial name
- NCT06762301
- Testing
- sexual education and counseling, Routine clinical care
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Relationship Distress, Marital Conflict
A Pilot Study of OurRelationship.dk, a Web-based Self-help-Program for Couples With High Levels of Conflict or Distress
The aim of this study is twofold 1) to conduct a pilot test of methods for a larger scale RCT study evaluating the efficacy of OurRelationship offered to couples with high levels of conflict or distress and at least one child at…
- Conditions
- Relationship Distress, Marital Conflict, Family Relationship
- Trial name
- NCT04588012
- Testing
- The online self-help Program OurRelationship developed by prof. Brian Doss and prof. Andrew Christensen., The off line self-help course "Pas på Parforholdet".
- Where
- Denmark
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Control of Pregnancy, Prevention of Sexually Transmitted Infections
A Clinical Investigation to Assess the Performance of a Polyurethane Condom Versus a Latex Condom in Healthy Monogamous Couples
This investigation is designed to evaluate the performance rate of a polyurethane (PU) condom versus a standard natural rubber latex (NRL) condom.
- Trial name
- NCT04134039
- Testing
- Polyurethane (PU) condom, Natural Rubber Latex (NRL) condom
- Where
- Thailand
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited