Clinical trials: Costs
Arthroplasty, Replacement, Hip
Alberta Hip Improvement Project
A study to determine the effectiveness and safety of the use of metal-on-metal hip resurfacing (for example the birmingham hip) when compared to conventional total hip replacement.
- Trial name
- NCT00293774
- Where
- Canada
- Volunteers
- 1,632 people
- Sponsor
- Alberta Bone and Joint Health Institute
Lung Cancer, Thoracic Cancer
Signia Stapler Versus Vessel Sealer Extend Energy Device With SureForm Stapling in Robotic-Assisted Segmentectomy
Robotic-assisted thoracoscopic surgery (RTS) segmentectomy is safe and effective for patients with early-stage non-small cell lung cancer (NSCLC).
- Conditions
- Lung Cancer, Thoracic Cancer, Lung Neoplasm
- Trial name
- NCT05727735
- Testing
- Medtronic Signia Stapler, Da Vinci Vessel Sealer Extend Energy Device with SureForm Stapling
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Complication, Infection
Culture-guided Antimicrobial Prophylaxis in Men Undergoing Prostate Biopsy.
This study aims to assess the effectiveness and cost-effectiveness of rectal swab culture-guided antimicrobial prophylaxis to reduce infectious complications after transrectal prostate biopsy.
- Conditions
- Complication, Infection, Prostate Cancer
- Trial name
- pro-SWAP (NCT03228108)
- Testing
- Ciprofloxacin, Trimethoprim/Sulfamethoxazole, Fosfomycin
- Where
- 13 sites in Netherlands
- Volunteers
- 1,538 people
- Sponsor
- Radboud University Medical Center
Rheumatoid Arthritis
Optimal Management of Rheumatoid Arthritis Patients Requiring Biologic Therapy
That anti-TNF therapy and rituximab therapy are equally effective in treating patients with rheumatoid arthritis who meet the eligibility criteria for biologic therapy in the British Society for Rheumatology guidelines, and have…
- Trial name
- ORBIT (NCT01021735)
- Testing
- etanercept or adalimumab, Rituximab
- Where
- 8 sites in United Kingdom
- Volunteers
- 302 people
- Sponsor
- University of Glasgow
Neurodegenerative Diseases, Memory Disturbances
Health Technology Assessment of Diagnostic Approaches in Alzheimer's Disease
Background: New research criteria for the diagnosis of Alzheimer's disease (AD) have recently been developed to enable an early diagnosis of AD pathophysiology by relying on emerging biomarkers.
- Trial name
- NCT01450891
- Where
- 4 sites in Netherlands
- Volunteers
- 304 people
- Sponsor
- Maastricht University Medical Center
Critical Illness
Cost Effectiveness Analysis of Critical Care in Resource Limited Setting
The purpose of this study was to examine the cost effectiveness of critical care in a middle income country with limited resources. The main study hypothesis was that critical care is cost effective in low resources setting.
- Trial name
- CEACCLR (NCT02556476)
- Testing
- mechanical ventilation, neuromuscular blockade, renal replacement therapy
- Volunteers
- 148 people
- Sponsor
- University of Sarajevo
Multiple Sclerosis
Physical Function, Health and Employment for People With Multiple Sclerosis
Employment is low in people with MS, even when physical levels of functioning are high. The purpose of this study is to investigate if an individually tailored intervention combining individualized physiotherapy and work…
- Trial name
- NCT06110468
- Testing
- CoreDISTParticipation
- Where
- Norway
- Volunteers
- 114 people
- Sponsor
- Nordlandssykehuset HF
Anemia, Neoplasms
Cost-effectiveness Study of Epoetin Alfa and Darbepoetin Alfa in Adult Patients With Cancer Who Have Anemia
The purpose of this study is to evaluate the cost-effectiveness of epoetin alfa compared with darbepoetin alfa in the treatment of anemia in adults receiving chemotherapy for cancer.
- Trial name
- NCT00264108
- Testing
- Darbepoetin alfa, Epoetin alfa
- Where
- 20 sites in Netherlands
- Volunteers
- 492 people
- Sponsor
- Janssen-Cilag B.V.
Schizophrenia, Schizoaffective Disorder
Risperdal Consta and Health Care Utilization in Patients With Schizophrenia
The purpose of this study is to determine if Risperdal Consta will affect the healthcare utilization costs in chronically ill schizophrenic patients with multiple admissions to the psychiatric hospital compared to the previous…
- Trial name
- NCT00313391
- Testing
- Risperdal Consta
- Where
- United States
- Sponsor
- Emory University
Cerebral Palsy
Quantifying Energetic Demands of Walking for People With Cerebral Palsy
The purpose of this study is to examine the underlying mechanisms that contribute to high energy costs for people with cerebral palsy (CP) as they walk.
- Trial name
- NCT04303078
- Testing
- Varying levels of harness support during walking
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Washington
Smoking Cessation
A Cost-effectiveness Study of Nicotine Patches Distributed Through a Quitline
The study is to understand whether distribution of two different supplies of nicotine patches through a telephone quitline has an effect on quit rates. The two different supplies are four vs.
- Trial name
- NCT01889771
- Testing
- Nicotine Patch
- Volunteers
- 1,495 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Clinical Trial
Raising Healthy Children: A Hybrid Trial of the Family Check-Up 4 Health in Primary Care
This study is a hybrid implementation-effectiveness trial of the Family Check-Up 4 Health (FCU4Health), an adapted version of the Family Check-Up, in pediatric primary care.
- Trial name
- FCU4Health (NCT03013309)
- Testing
- Family Check-Up 4 Health, Treatment as usual
- Where
- 3 sites in United States
- Volunteers
- 240 people
- Sponsor
- Arizona State University
Surgical Site Infection
Antibiotic Prophylaxis in Clean Surgery. Impact on Surgical Site Infection
This is a randomized control study of antibiotic uses in clean non prosthetic surgeries. One group will be given antibiotic prophylaxis, other will receive a placebo.
- Trial name
- NCT03595852
- Testing
- Cefazolin
- Where
- Rwanda
- Volunteers
- 138 people
- Sponsor
- University of Rwanda
Mild Cognitive Impairment (MCI), Exercises
High-Amplitude Functional Exercises in Older Adults With Mild Cognitive Impairment
This study will investigate the effects of dual-task-based high-amplitude functional exercises on balance and functional mobility in older adults with mild cognitive impairment.
- Trial name
- NCT07762235
- Testing
- Dual-Task-Based High-Amplitude Functional Exercise Program, Traditional Balance and Mobility Exercise Group
- Volunteers
- 36 people
- Sponsor
- Istinye University
Rehabilitation, Spinal Fusion
Effect of a Case Manager to Assist the Rehabilitation for Lumbar Spinal Fusion Patients. A Randomised Controlled Trial.
The aim of the current study is to examine the effect of a case manager-assisting rehabilitation program compared to usual physical rehabilitation for patients undergoing a lumbar spinal fusion on functional disability, pain, and…
- Conditions
- Rehabilitation, Spinal Fusion, Case Managers
- Trial name
- NCT03433443
- Testing
- Case manager assisted rehabilitation, Usual physical rehabilitation
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Diabetic Macular Edema
Safety, Efficacy and Cost-efficacy of Ranibizumab (Monotherapy or Combination With Laser) in the Treatment of Diabetic Macular Edema (DME)
To evaluate, specifically within the Canadian medical environment, the efficacy, safety and cost-efficacy of ranibizumab administered either as combination therapy (ranibizumab plus laser photocoagulation), or as monotherapy in…
- Trial name
- RESPOND (NCT01135914)
- Testing
- ranibizumab, Laser
- Where
- 20 sites in Canada
- Volunteers
- 241 people
- Sponsor
- Novartis Pharmaceuticals
Asthma
CDC Medicaid Asthma Home Visit Project
Asthmatic children age 3-17 from low income households in King County are randomly assigned into a community health worker (CHW) intervention group and a control group.
- Trial name
- NCT02258308
- Testing
- CHW intervention
- Volunteers
- 373 people
- Sponsor
- Public Health - Seattle and King County
Premature Birth, Brain Injuries
Adding Motion to Contact: A New Model for Low-cost Family Centered Very-early Onset Intervention in Very Preterm-born Infants
This project is a Randomised Clinical Trial that includes a tactile-kinesthetic somatosensory stimulation or family centred education intervention with families of preterm infants at risk for sensori-motor disorders.
- Trial name
- NTM (NCT05542108)
- Testing
- Multisensory Stimulation and Family Education Group, Family Education Only Group (FEG)
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- University of Pisa
Malaria, Soil Transmitted Helminths
Effectiveness and Cost-effectiveness of Integrated Model for Malaria and Helminth Control
Malaria remains a major health problem, especially among children living in sub-Saharan Africa where more than 90% of the disease and deaths occur.
- Conditions
- Malaria, Soil Transmitted Helminths, Schistosomiasis, Seasonal Malaria Chemoprevention
- Trial name
- MALHELMIN (NCT06182176)
- Testing
- Sulphadoxine-pyrimethamine and Amodiaquine
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Colon Cancer, Colonoscopy
Impact of a Novel Patient Educational Booklet on Colonoscopy Quality
Background: Achievement of colonoscopy outcomes depends on high-quality bowel preparation by patients; yet inadequate preparation is common.
- Trial name
- NCT00975247
- Testing
- Receiving an educational booklet
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- VA Greater Los Angeles Healthcare System