Clinical trials: Cost Benefit Analysis
Esthetic Zone, Single Tooth Lost
Cost Effectiveness of Various Implant Placement Protocols in the Esthetic Zone
Loss of teeth in the anterior upper jaw significantly affects both well-being and chewing function. Nowadays, dental implants are the treatment of choice for replacing missing teeth with fixed dental prostheses and are often…
- Conditions
- Esthetic Zone, Single Tooth Lost, Accuracy of Dental Implants, Dimensional Changes
- Trial name
- NCT05940662
- Testing
- Immediate Implant Placement, Early Implant Placement, Late Implant Placement
- Where
- Switzerland
- Volunteers
- 160 people
- Sponsor
- University of Bern
Stroke Sequelae
Telerehabilitation for Post-stroke Patients
In the last few years, there has been an increasing shift towards outpatients setting in the care of patients with stroke. Unfortunately, this led to a high percentage of discharged patients who did not receive an adequate amount…
- Trial name
- NCT04413240
- Testing
- Telerehabilitation, Conventional rehabilitation
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Universita di Verona
Surgical Site Infection
Comparative Effectiveness and Cost-Benefit Analysis of Vancomycin Powder in High Risk Spine Surgery Patients
Despite the use of prophylactic systemic antibiotics and improved surgical technique, surgical site infections remain a serious concern.
- Trial name
- NCT01566422
- Testing
- Vancomycin powder
- Where
- United States
- Sponsor
- Vanderbilt University Medical Center
Postoperative Complications, Cost-Benefit Analysis
Advanced Recovery Room Care II - Improved Recovery After Surgery
Moderate-risk surgical patients have a very high incidence of early serious postoperative complications (approximately 50% at Royal Adelaide Hospital, RAH).
- Trial name
- ARRCII (NCT04769518)
- Testing
- Advanced Recovery Room Care (ARRC)
- Where
- Australia
- Volunteers
- 857 people
- Sponsor
- University of Adelaide
HIV
Gathering Records to Evaluate Antiretroviral Treatment-South Africa
To achieve global goals for the treatment of HIV, most high-prevalence countries are experimenting with and scaling up differentiated service delivery models (DSD).
- Trial name
- GREAT (NCT04149782)
- Testing
- Routine medical record data collection
- Where
- South Africa
- Volunteers
- 7,000,000 people
- Sponsor
- Boston University
Drug-resistant Tuberculosis, HIV Coinfection
Pragmatic Use of Next-generation Sequencing for Management of Drug-resistant Tuberculosis
TS ELiOT is a stepped-wedge, cluster randomized trial assessing the effect of a next-generation sequencing-based strategy on rifampin-resistant tuberculosis management and patient outcomes.
- Conditions
- Drug-resistant Tuberculosis, HIV Coinfection, Cost-Benefit Analysis
- Trial name
- TSELiOT (NCT05553236)
- Testing
- Targeted next-generation sequencing
- Where
- South Africa
- Volunteers
- 2,500 people
- Sponsor
- University of California, San Francisco
Pregnancy Complications Nos, Labor/Delivery Problems Nos
Early Postnatal Discharge in a French Perinatal Network
The purpose of this "before-after" study is to determine the effectiveness of a multidimensional intervention to increase the rate for early discharge of low-risk mothers and the healthy newborn in a perinatal network.
- Conditions
- Pregnancy Complications Nos, Labor/Delivery Problems Nos, Vitality; Newborn
- Trial name
- SORPRISE (NCT02298569)
- Testing
- multi-pronged program to improve early postpartum discharge
- Where
- 5 sites in France
- Volunteers
- 800 people
- Sponsor
- University Hospital, Grenoble
Colorectal Neoplasm
Enhancing Prevention Pathways Toward Tribal Colorectal Health
Recent improvements in colorectal cancer (CRC) incidence, mortality, stage at diagnosis, and survival in the general U.S. population have been attributed to routine screening with prompt removal of polyps, early detection, and…
- Trial name
- NCT02882620
- Testing
- High Intensity (Group 1), Medium Intensity (Group 2), Reference Group (Group 3)
- Where
- United States
- Volunteers
- 1,788 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Parenting, Parent-Child Relations
Delivering Evidence-Based Parenting Services to Families in Child Welfare Using Telehealth
The goal of this randomized controlled trial is to compare Promoting First Relationships - Home Visit (PFR-HV) to Promoting First Relationships - Telehealth (PFR-T) among parents of 6-12 month olds in the child welfare system.
- Conditions
- Parenting, Parent-Child Relations, Child Behavior, Child Maltreatment
- Trial name
- NCT06109766
- Testing
- Promoting First Relationships
- Where
- United States
- Volunteers
- 357 people, healthy volunteers welcome
- Sponsor
- University of Washington
Colorectal Neoplasms
Quality of Life of Patients With Colorectal Neoplasm and Cost-Effectiveness Analysis of Colorectal Cancer Screening
Introduction: Colorectal cancer (CRC) is the second most common cancer among Chinese in Hong Kong and the second leading cause of cancer death in this population.
- Trial name
- NCT02038283
- Where
- 3 sites in Hong Kong
- Volunteers
- 587 people
- Sponsor
- The University of Hong Kong
Chronic Disease
Biomarker Cost-Benefit Analysis of EFNEP
The goal of this integrated project is to assess whether EFNEP is a cost-effective nutrition education intervention that generates sustained improvement in chronic disease biomarkers.
- Trial name
- NCT05558085
- Testing
- Expanded Food and Nutrition Education Program (EFNEP)
- Where
- 4 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- South Dakota State University
Hyperglycemia, Obesity
Primary Care Community Partnerships to Prevent Diabetes
The purpose of this study is to determine if providing free-of-charge access to a group-based lifestyle intervention delivered in partnership with the community is cost-effective for the prevention of type 2 diabetes.
- Conditions
- Hyperglycemia, Obesity, Diabetes Mellitus
- Trial name
- RAPID (NCT00656682)
- Testing
- Dietitian Counseling Alone, Dietitian Plus Community Group Lifestyle
- Where
- United States
- Volunteers
- 509 people
- Sponsor
- Northwestern University
Postoperative Complications
Clinical Outcomes and Costs Analyses in Use of Goal Directed Therapy
The aim of the study is to evaluate clinical and economic impact of Goal Directed Fluid Therapy according to NICE haemodynamic protocol.
- Trial name
- NCT01995786
- Testing
- Goal Directed Fluid Therapy FloTrac/Vigileo
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Regina Elena Cancer Institute
Neoplasms
Pharmacogenomic and Pharmacokinetic Safety and Cost-saving Analysis in Patients Treated With Fluoropyrimidines
The primary purpose of this study is to prospectively determine whether capecitabine and 5-FU-induced toxicity is preventable by dose reduction prior to start of the first administration in patients heterozygous or homozygous…
- Trial name
- NCT00838370
- Testing
- Capecitabine, 5-fluorouracil
- Where
- 3 sites in Netherlands
- Volunteers
- 22 people
- Sponsor
- The Netherlands Cancer Institute
Emotional Disorder
Cost-effectiveness of a Transdiagnostic Psychological Treatment for Emotional Disorders in Primary Care
The aim of this study is to test the cost-effectiveness and cost-utility of adding a transdiagnostic group cognitive-behavioural therapy (TD-CBT) to treatment as usual (TAU) for emotional disorders in primary care .
- Trial name
- PsicAP-Costs2 (NCT05314920)
- Testing
- Transdiagnostic cognitive-behavioral therapy (TD-CBT), Bernstein and Borkovec progressive muscle relaxation (PMR)
- Where
- 4 sites in Spain
- Volunteers
- 300 people
- Sponsor
- Instituto de Investigación Marqués de Valdecilla
HIV
Gathering Records to Evaluate Antiretroviral Treatment-Zambia (GREAT )
To achieve global goals for the treatment of HIV, most high-prevalence countries are experimenting with and scaling up differentiated service delivery models (DSD).
- Trial name
- GREAT (NCT04158882)
- Testing
- Routine medical record data collection
- Where
- Zambia
- Volunteers
- 1,200,000 people
- Sponsor
- Boston University
Chronic Pain, Musculoskeletal Pain
Implementation of a Behavioural Medicine Approach in Physical Therapy for Treatment of Chronic Pain
Implementation of a behavioral medicine (BM) approach in physical therapy (PT) for patients with persistent musculoskeletal pain is in accordance with the state of science.
- Trial name
- NCT03118453
- Testing
- Active implementation clinics, Passive implementation clinics
- Where
- 3 sites in Sweden
- Volunteers
- 109 people
- Sponsor
- Mälardalen University
Depressive Disorder
Increasing Cost-effectiveness of Inpatient Treatment of Affective Disorders
The cost-effectiveness of a new, guideline oriented sequential inpatient - outpatient treatment model will be investigated. Secondary outcomes are: patient satisfaction, practitioners' satisfaction and influence on work.
- Trial name
- INCA (NCT00662428)
- Testing
- Symptom based discharge management, Treatment as usual
- Where
- 5 sites in Germany
- Volunteers
- 202 people
- Sponsor
- University Hospital Freiburg
Arhythmia
Comparison and Analysis of Functionality, Safety, Cost-effectiveness, and Environmental Impact of Reprocessed and New Ablation Catheters in Electrophysiological Procedures.
This study evaluates whether re-sterilized (reprocessed) ablation catheters are as effective and safe as new ablation catheters when used for electrophysiological procedures.
- Trial name
- RE-USE EP (NCT07522424)
- Testing
- Ablation - new, Ablation - reprocessed
- Where
- Croatia
- Volunteers
- 200 people
- Sponsor
- Ivan Zeljkovic
Prostatic Hyperplasia
Establishing the Benefits of Adherence to Enlarged Prostate Treatment: A Validation Study Linking Adherence to Outcomes Using the Market Scan Database
Adherence and length of therapy with 5-alpha reductase inhibitor (5ARI) treatment may be associated with improved clinical outcomes of enlarged prostate (EP) as well as lower health care costs.
- Trial name
- NCT01381510
- Testing
- 5-alpha Reductase Inhibitor (5ARI)
- Volunteers
- 54,459 people
- Sponsor
- GlaxoSmithKline